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Search results 101 to 117 out of 117 for Ttbk1

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Type Details Score
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Protein
Q3UVR3
Organism: Mus musculus/domesticus
Length: 1243  
Fragment?: false
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Protein
Q3UVR3-2
Organism: Mus musculus/domesticus
Length: 1201  
Fragment?: false
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Allele
Ttbk1<em1Smoc> | MGI:7293029
Name: tau tubulin kinase 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Protein Coding Gene
MGI:2155779 | Ttbk2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
20096481 | -
First Author: Vázquez-Higuera JL
Year: 2011
Journal: Neurobiol Aging
Title: Genetic variations in tau-tubulin kinase-1 are linked to Alzheimer's disease in a Spanish case-control cohort.
Volume: 32
Issue: 3
Pages: 550.e5-9
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Protein Domain
IPR042714 | TTBK1_STKc
Type: Domain
Description: STKs (serine/threonine-protein kinases) catalyse the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. TTBK is a neuron-specific kinase that phosphorylates the microtubule-associated protein tau and promotes its aggregation. Higher vertebrates contain two TTBK proteins, TTBK1 and TTBK2, both of which have been implicated in neurodegeneration. Genetic variations in TTBK1 are linked to Alzheimer's disease (AD). Hyperphosphorylated tau is a major component of paired helical filaments that accumulate in the brain of AD patients []. Studies in transgenic mice show that TTBK1 is involved in the phosphorylation-dependent pathogenic aggregation of tau [, ].
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Publication
33228809 | J:311837
First Author: McMillan P
Year: 2020
Journal: Acta Neuropathol Commun
Title: Adult onset pan-neuronal human tau tubulin kinase 1 expression causes severe cerebellar neurodegeneration in mice.
Volume: 8
Issue: 1
Pages: 200
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Publication
19118186 | J:144029
First Author: Sato S
Year: 2008
Journal: J Neurosci
Title: Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgenic mice expressing tau-tubulin kinase 1.
Volume: 28
Issue: 53
Pages: 14511-21
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Protein
Q6PCN3
Organism: Mus musculus/domesticus
Length: 1308  
Fragment?: false
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