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Search results 1101 to 1116 out of 1116 for Mapk8

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0.017s

Type

Details

Score

Strain

MGI:5003652 | STOCK Tg(Mapk8-EGFP)FV33Gsat/Mmucd

Attribute String:

mutant stock, transgenic

•

Allele

Gt(ROSA)26Sor<tm1(CAG-MAP2K7*/MAPK8,-EGFP)Ftw> | MGI:5494696

Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 1, F Thomas Wunderlich
Allele Type:	Targeted
Attribute String:	Conditional ready, Constitutively active, Humanized sequence, Inserted expressed sequence, Reporter

•

Publication

31533924 | J:284125

First Author:	Qin Y
Year:	2019
Journal:	Development
Title:	WDR62 is involved in spindle assembly by interacting with CEP170 in spermatogenesis.
Volume:	146
Issue:	20

•

Protein Domain

IPR038498 | OspF/SpvC_sf

Type:

Homologous_superfamily

Description:

This entry includes the virulence protein SpvC and the phosphothreonine lyase OspF. OspF catalyses the removal of the phosphate group from the phosphothreonine in the mitogen-activated protein kinases such as MAPK2/ERK2, MAPK3/ERK1, MAPK8 and MAPK14 in an irreversible reaction, thus preventing the downstream phosphorylation of histone H3. This epigenetic modification results in inhibition of the transcription of a specific subset of proinflammatory genes, and ultimately to a reduced immune response against the invading pathogen. The diminished immune response enhances the bacterium's ability to disseminate and multiply within the host [, , ].The spv region of the Salmonella virulence plasmids consists of five genes located on an 8-kb fragment, shown to be essential for virulence in mice []. SpvC (also known as mkfA and VirA []) is part of this gene cluster and is utilised by the microbe upon entry into macrophages, although the exact mechanism is unclear.

•

Protein Domain

IPR003519 | OspF/SpvC

Type:

Family

Description:

•

Genotype

Symbol:	Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Ckmm-cre)5Khn/?
Background:	involves: C57BL/6 * FVB
Zygosity:	cn
Has Mutant Allele:	true

•

Publication

17159983 | -

First Author:	Arbibe L
Year:	2007
Journal:	Nat Immunol
Title:	An injected bacterial effector targets chromatin access for transcription factor NF-kappaB to alter transcription of host genes involved in immune responses.
Volume:	8
Issue:	1
Pages:	47-56

•

Publication

17305427 | -

First Author:	Kramer RW
Year:	2007
Journal:	PLoS Pathog
Title:	Yeast functional genomic screens lead to identification of a role for a bacterial effector in innate immunity regulation.
Volume:	3
Issue:	2
Pages:	e21

•

Publication

17303758 | -

First Author:	Li H
Year:	2007
Journal:	Science
Title:	The phosphothreonine lyase activity of a bacterial type III effector family.
Volume:	315
Issue:	5814
Pages:	1000-3

•

Publication

1400193 | -

First Author:	Roudier C
Year:	1992
Journal:	J Bacteriol
Title:	Characterization of translation termination mutations in the spv operon of the Salmonella virulence plasmid pSDL2.
Volume:	174
Issue:	20
Pages:	6418-23

•

Publication

1378053 | -

First Author:	Krause M
Year:	1992
Journal:	J Bacteriol
Title:	Regulation of plasmid virulence gene expression in Salmonella dublin involves an unusual operon structure.
Volume:	174
Issue:	13
Pages:	4482-9

•

Publication

29749399 | J:269488

First Author:	Heaton WL
Year:	2018
Journal:	Leukemia
Title:	Autocrine Tnf signaling favors malignant cells in myelofibrosis in a Tnfr2-dependent fashion.

•

Publication

15254788 | J:96648

First Author:	Katoh M
Year:	2004
Journal:	Int J Mol Med
Title:	Identification and characterization of ARHGAP24 and ARHGAP25 genes in silico.
Volume:	14
Issue:	2
Pages:	333-8

•

Publication

28218919 | J:251277

First Author:	Wang PX
Year:	2017
Journal:	Nat Med
Title:	Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates.
Volume:	23
Issue:	4
Pages:	439-449

•

Publication

29106399 | J:252611

First Author:	Awazawa M
Year:	2017
Journal:	Nat Med
Title:	A microRNA screen reveals that elevated hepatic ectodysplasin A expression contributes to obesity-induced insulin resistance in skeletal muscle.
Volume:	23
Issue:	12
Pages:	1466-1473

•

Publication

- | J:100256

First Author:	The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year:	2005
Journal:	Database Download
Title:	MGI download of GENSAT transgene data

•

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Search results 1101 to 1116 out of 1116 for Mapk8

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