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Search results 201 to 300 out of 401 for Cope

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Type Details Score
Publication
6088227 | -
First Author: Zahradka P
Year: 1984
Journal: Eur J Biochem
Title: Poly(ADP-ribose) polymerase is a zinc metalloenzyme.
Volume: 142
Issue: 3
Pages: 503-9
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Protein Domain
IPR008288 | PARP
Type: Family
Description: Poly(ADP-ribose) synthase and poly(ADP-ribose) polymerase (PARP, also known as ADPRT) catalyse the DNA-dependent covalent attachment of ADP-ribose to various nuclear proteins []. They are used by the eukaryotic cell to cope with numerous environmental and endogenous genotoxic agents that cause DNA strand breaks. PARP plays a role in many cellular processes, including DNA repair, recombination, cell proliferation and death, as well as genomic stability []. The DNA-binding region of the protein contains a pair of zinc finger domains, which have been shown to bind DNA in a zinc-dependent manner []. PARP also contains a BRCT domain involved in cell cycle checkpoint functions responsive to DNA damage [], a catalyic domain and a regulatory domain.
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Publication
29073063 | J:285000
First Author: Torregrosa-Muñumer R
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: PrimPol is required for replication reinitiation after mtDNA damage.
Volume: 114
Issue: 43
Pages: 11398-11403
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Publication
8009221 | J:36115
First Author: Müller U
Year: 1994
Journal: Science
Title: Functional role of type I and type II interferons in antiviral defense.
Volume: 264
Issue: 5167
Pages: 1918-21
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Publication
15864262 | -
First Author: Gerdes K
Year: 2005
Journal: Nat Rev Microbiol
Title: Prokaryotic toxin-antitoxin stress response loci.
Volume: 3
Issue: 5
Pages: 371-82
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Publication
17538026 | -
First Author: Jin QW
Year: 2007
Journal: Mol Biol Cell
Title: The nucleolar Net1/Cfi1-related protein Dnt1 antagonizes the septation initiation network in fission yeast.
Volume: 18
Issue: 8
Pages: 2924-34
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Publication
30643283 | J:273578
First Author: Kelkar DS
Year: 2019
Journal: Nat Chem Biol
Title: A chemical-genetic screen identifies ABHD12 as an oxidized-phosphatidylserine lipase.
Volume: 15
Issue: 2
Pages: 169-178
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Publication
28561733 | J:276378
   
First Author: Paulino C
Year: 2017
Journal: Elife
Title: Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A.
Volume: 6
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Publication
27212239 | J:233671
First Author: Wang QC
Year: 2016
Journal: Cell
Title: TMCO1 Is an ER Ca(2+) Load-Activated Ca(2+) Channel.
Volume: 165
Issue: 6
Pages: 1454-1466
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Publication
21873995 | J:315472
First Author: Takahashi N
Year: 2011
Journal: Nat Chem Biol
Title: TRPA1 underlies a sensing mechanism for O2.
Volume: 7
Issue: 10
Pages: 701-11
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Publication
27841882 | J:260936
First Author: Shingu T
Year: 2017
Journal: Nat Genet
Title: Qki deficiency maintains stemness of glioma stem cells in suboptimal environment by downregulating endolysosomal degradation.
Volume: 49
Issue: 1
Pages: 75-86
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Publication
30146480 | J:272551
First Author: Chee YC
Year: 2018
Journal: Dev Cell
Title: Intrinsic Xenobiotic Resistance of the Intestinal Stem Cell Niche.
Volume: 46
Issue: 6
Pages: 681-695.e5
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Publication
33271062 | J:302995
First Author: Najafov A
Year: 2021
Journal: Mol Cell
Title: RIPK1 Promotes Energy Sensing by the mTORC1 Pathway.
Volume: 81
Issue: 2
Pages: 370-385.e7
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Publication
20600911 | J:163006
First Author: Yefimova MG
Year: 2010
Journal: Neurobiol Dis
Title: Polyglutamine toxicity induces rod photoreceptor division, morphological transformation or death in spinocerebellar ataxia 7 mouse retina.
Volume: 40
Issue: 1
Pages: 311-24
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Publication
36198265 | J:329914
First Author: Gao F
Year: 2022
Journal: Cell Rep
Title: A non-canonical retina-ipRGCs-SCN-PVT visual pathway for mediating contagious itch behavior.
Volume: 41
Issue: 1
Pages: 111444
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Publication
16432513 | J:105783
First Author: Kawano T
Year: 2006
Journal: Nat Med
Title: Prostaglandin E2 EP1 receptors: downstream effectors of COX-2 neurotoxicity.
Volume: 12
Issue: 2
Pages: 225-9
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Publication
17276353 | J:129768
First Author: Guo F
Year: 2007
Journal: Cell Metab
Title: The GCN2 eIF2alpha kinase regulates fatty-acid homeostasis in the liver during deprivation of an essential amino acid.
Volume: 5
Issue: 2
Pages: 103-14
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Publication
25959047 | J:224889
 
First Author: Ip WK
Year: 2015
Journal: Nat Commun
Title: Macrophages monitor tissue osmolarity and induce inflammatory response through NLRP3 and NLRC4 inflammasome activation.
Volume: 6
Pages: 6931
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Publication
28753606 | J:244004
First Author: Ruiz R
Year: 2017
Journal: PLoS Genet
Title: The RhoJ-BAD signaling network: An Achilles' heel for BRAF mutant melanomas.
Volume: 13
Issue: 7
Pages: e1006913
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Publication
15649694 | J:134624
First Author: von Kienlin M
Year: 2005
Journal: Neurobiol Dis
Title: Altered metabolic profile in the frontal cortex of PS2APP transgenic mice, monitored throughout their life span.
Volume: 18
Issue: 1
Pages: 32-9
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Publication
26674215 | J:228281
 
First Author: Gali Ramamoorthy T
Year: 2015
Journal: Nat Commun
Title: The transcriptional coregulator PGC-1β controls mitochondrial function and anti-oxidant defence in skeletal muscles.
Volume: 6
Pages: 10210
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Publication
23395000 | J:196610
First Author: Huber AL
Year: 2013
Journal: Mol Cell
Title: p58(IPK)-mediated attenuation of the proapoptotic PERK-CHOP pathway allows malignant progression upon low glucose.
Volume: 49
Issue: 6
Pages: 1049-59
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Publication
25751136 | J:221896
 
First Author: Matsuda T
Year: 2015
Journal: Nat Commun
Title: TLR9 signalling in microglia attenuates seizure-induced aberrant neurogenesis in the adult hippocampus.
Volume: 6
Pages: 6514
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Publication
28970536 | J:255756
First Author: Neueder A
Year: 2017
Journal: Sci Rep
Title: HSF1-dependent and -independent regulation of the mammalian in vivo heat shock response and its impairment in Huntington's disease mouse models.
Volume: 7
Issue: 1
Pages: 12556
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Publication
27829143 | J:240977
First Author: Marshall KL
Year: 2016
Journal: Cell Rep
Title: Touch Receptors Undergo Rapid Remodeling in Healthy Skin.
Volume: 17
Issue: 7
Pages: 1719-1727
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Publication
27428651 | J:238123
First Author: Shemesh Y
Year: 2016
Journal: Nat Neurosci
Title: Ucn3 and CRF-R2 in the medial amygdala regulate complex social dynamics.
Volume: 19
Issue: 11
Pages: 1489-1496
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Publication
29320729 | J:271148
First Author: Nasser W
Year: 2018
Journal: Cell Rep
Title: Corneal-Committed Cells Restore the Stem Cell Pool and Tissue Boundary following Injury.
Volume: 22
Issue: 2
Pages: 323-331
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Publication
22949508 | J:189241
First Author: Khalil H
Year: 2012
Journal: Mol Cell Biol
Title: Caspase-3 protects stressed organs against cell death.
Volume: 32
Issue: 22
Pages: 4523-33
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Publication
16923392 | J:115988
First Author: Oyadomari S
Year: 2006
Journal: Cell
Title: Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload.
Volume: 126
Issue: 4
Pages: 727-39
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Publication
35996084 | J:347236
First Author: Kaneko T
Year: 2022
Journal: J Physiol Sci
Title: Hypothalamic orexinergic neurons modulate pain and itch in an opposite way: pain relief and itch exacerbation.
Volume: 72
Issue: 1
Pages: 21
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Publication
22169038 | J:179377
First Author: Libert S
Year: 2011
Journal: Cell
Title: SIRT1 activates MAO-A in the brain to mediate anxiety and exploratory drive.
Volume: 147
Issue: 7
Pages: 1459-72
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Publication
34555357 | J:334103
First Author: Scheiblich H
Year: 2021
Journal: Cell
Title: Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes.
Volume: 184
Issue: 20
Pages: 5089-5106.e21
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Publication
17765680 | J:145116
First Author: Yamamoto K
Year: 2007
Journal: Dev Cell
Title: Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1.
Volume: 13
Issue: 3
Pages: 365-76
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Publication
35707720 | J:328998
First Author: Macchi C
Year: 2022
Journal: iScience
Title: Monocarboxylate transporter 1 deficiency impacts CD8+ T lymphocytes proliferation and recruitment to adipose tissue during obesity.
Volume: 25
Issue: 6
Pages: 104435
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Publication
24300895 | J:248759
First Author: Revollo JR
Year: 2013
Journal: Sci Signal
Title: HES1 is a master regulator of glucocorticoid receptor-dependent gene expression.
Volume: 6
Issue: 304
Pages: ra103
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Publication
19426692 | J:323307
First Author: Tenorio-Laranga J
Year: 2009
Journal: Biochem Pharmacol
Title: Sex-dependent compensated oxidative stress in the mouse liver upon deletion of catechol O-methyltransferase.
Volume: 77
Issue: 9
Pages: 1541-52
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Publication
15105825 | J:90345
First Author: Espejel S
Year: 2004
Journal: EMBO Rep
Title: Shorter telomeres, accelerated ageing and increased lymphoma in DNA-PKcs-deficient mice.
Volume: 5
Issue: 5
Pages: 503-9
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Publication
15748210 | J:96887
First Author: Scalzo AA
Year: 2005
Journal: Immunol Cell Biol
Title: NK gene complex haplotype variability and host resistance alleles to murine cytomegalovirus in wild mouse populations.
Volume: 83
Issue: 2
Pages: 144-9
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Publication
38382525 | J:346122
First Author: Zaffagnini G
Year: 2024
Journal: Cell
Title: Mouse oocytes sequester aggregated proteins in degradative super-organelles.
Volume: 187
Issue: 5
Pages: 1109-1126.e21
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Publication
31747588 | J:300797
First Author: Hsieh YL
Year: 2019
Journal: Cell Rep
Title: NPGPx-Mediated Adaptation to Oxidative Stress Protects Motor Neurons from Degeneration in Aging by Directly Modulating O-GlcNAcase.
Volume: 29
Issue: 8
Pages: 2134-2143.e7
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Publication
26417950 | J:227063
 
First Author: Santos FJ
Year: 2015
Journal: Elife
Title: Corticostriatal dynamics encode the refinement of specific behavioral variability during skill learning.
Volume: 4
Pages: e09423
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Publication
18413607 | J:248220
First Author: Gertz M
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Activation of the lifespan regulator p66Shc through reversible disulfide bond formation.
Volume: 105
Issue: 15
Pages: 5705-9
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Publication
8258325 | J:16155
First Author: Marusić-Galesić S
Year: 1993
Journal: Eur J Immunol
Title: Increased number of cytotoxic T cells within CD4+8- T cells in beta 2-microglobulin, major histocompatibility complex class I-deficient mice.
Volume: 23
Issue: 12
Pages: 3115-9
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Publication
9875670 | J:52328
First Author: Amici A
Year: 1998
Journal: Cancer Immunol Immunother
Title: Genetic immunization against neu/erbB2 transgenic breast cancer.
Volume: 47
Issue: 4
Pages: 183-90
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Publication
14960357 | J:88771
First Author: Bartholdy B
Year: 2004
Journal: Gene
Title: Transcriptional control of B cell development and function.
Volume: 327
Issue: 1
Pages: 1-23
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Publication
18285820 | J:132680
First Author: Hakem R
Year: 2008
Journal: EMBO J
Title: DNA-damage repair; the good, the bad, and the ugly.
Volume: 27
Issue: 4
Pages: 589-605
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Publication
31471318 | J:282969
First Author: Ko HR
Year: 2019
Journal: J Biol Chem
Title: SIAH1 ubiquitin ligase mediates ubiquitination and degradation of Akt3 in neural development.
Volume: 294
Issue: 42
Pages: 15435-15445
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Publication
22238096 | J:179904
First Author: Xiong X
Year: 2012
Journal: J Neurosci
Title: A conditioning lesion protects axons from degeneration via the Wallenda/DLK MAP kinase signaling cascade.
Volume: 32
Issue: 2
Pages: 610-5
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Publication
25712477 | J:220246
First Author: Galluzzi L
Year: 2015
Journal: EMBO J
Title: Autophagy in malignant transformation and cancer progression.
Volume: 34
Issue: 7
Pages: 856-80
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Publication
27043084 | J:236641
First Author: Su KH
Year: 2016
Journal: Nat Cell Biol
Title: HSF1 critically attunes proteotoxic stress sensing by mTORC1 to combat stress and promote growth.
Volume: 18
Issue: 5
Pages: 527-39
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Publication
28988825 | J:255960
First Author: Andrzejewski S
Year: 2017
Journal: Cell Metab
Title: PGC-1α Promotes Breast Cancer Metastasis and Confers Bioenergetic Flexibility against Metabolic Drugs.
Volume: 26
Issue: 5
Pages: 778-787.e5
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Publication
29148973 | J:254994
   
First Author: Marrack P
Year: 2017
Journal: Elife
Title: The somatically generated portion of T cell receptor CDR3α contributes to the MHC allele specificity of the T cell receptor.
Volume: 6
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Publication
29674659 | J:263598
First Author: Abe Y
Year: 2018
Journal: Nat Commun
Title: Histone demethylase JMJD1A coordinates acute and chronic adaptation to cold stress via thermogenic phospho-switch.
Volume: 9
Issue: 1
Pages: 1566
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Publication
19424842 | J:275981
First Author: Nadon NL
Year: 2008
Journal: Age (Dordr)
Title: Design of aging intervention studies: the NIA interventions testing program.
Volume: 30
Issue: 4
Pages: 187-99
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Publication
32692974 | J:297181
First Author: Lee AK
Year: 2020
Journal: Mol Cell
Title: Translational Repression of G3BP in Cancer and Germ Cells Suppresses Stress Granules and Enhances Stress Tolerance.
Volume: 79
Issue: 4
Pages: 645-659.e9
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Publication
32943635 | J:297263
First Author: Gremke N
Year: 2020
Journal: Nat Commun
Title: mTOR-mediated cancer drug resistance suppresses autophagy and generates a druggable metabolic vulnerability.
Volume: 11
Issue: 1
Pages: 4684
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Publication
26435690 | J:319609
First Author: Ajiro M
Year: 2015
Journal: Int J Biol Sci
Title: Adapted Resistance to the Knockdown Effect of shRNA-Derived Srsf3 siRNAs in Mouse Littermates.
Volume: 11
Issue: 11
Pages: 1248-56
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Publication
36230562 | J:330139
 
First Author: Lin Z
Year: 2022
Journal: Cancers (Basel)
Title: Lin28 Regulates Cancer Cell Stemness for Tumour Progression.
Volume: 14
Issue: 19
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Publication
15301529 | -
First Author: Yeremenko N
Year: 2004
Journal: Biochemistry
Title: Supramolecular organization and dual function of the IsiA chlorophyll-binding protein in cyanobacteria.
Volume: 43
Issue: 32
Pages: 10308-13
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HT Experiment
E-GEOD-25574 | Hypothalamic transcriptome plasticity in two rodent species reveals divergent differential gene expression but conserved pathways
Series Id: GSE25574
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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Publication
20660158 | J:182847
First Author: Muaddi H
Year: 2010
Journal: Mol Biol Cell
Title: Phosphorylation of eIF2α at serine 51 is an important determinant of cell survival and adaptation to glucose deficiency.
Volume: 21
Issue: 18
Pages: 3220-31
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Publication
17210579 | J:120898
First Author: Takeda K
Year: 2007
Journal: J Biol Chem
Title: Apoptosis signal-regulating kinase (ASK) 2 functions as a mitogen-activated protein kinase kinase kinase in a heteromeric complex with ASK1.
Volume: 282
Issue: 10
Pages: 7522-31
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Publication
21170151 | J:309913
First Author: Wu CC
Year: 2010
Journal: Protein Cell
Title: p38γ regulates UV-induced checkpoint signaling and repair of UV-induced DNA damage.
Volume: 1
Issue: 6
Pages: 573-83
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Publication
19259266 | J:147381
First Author: Valverde O
Year: 2009
Journal: PLoS One
Title: GPR3 receptor, a novel actor in the emotional-like responses.
Volume: 4
Issue: 3
Pages: e4704
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Publication
28827409 | J:249343
First Author: Martín-Pardillos A
Year: 2017
Journal: Blood
Title: Genomic and functional integrity of the hematopoietic system requires tolerance of oxidative DNA lesions.
Volume: 130
Issue: 13
Pages: 1523-1534
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Publication
11978729 | J:76204
First Author: Crozatier B
Year: 2002
Journal: FASEB J
Title: Role of creatine kinase in cardiac excitation-contraction coupling: studies in creatine kinase-deficient mice.
Volume: 16
Issue: 7
Pages: 653-60
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Publication
32417750 | J:298328
 
First Author: Ferreiro E
Year: 2020
Journal: Neurobiol Aging
Title: Chronic hyperglycemia impairs hippocampal neurogenesis and memory in an Alzheimer's disease mouse model.
Volume: 92
Pages: 98-113
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Publication
34987384 | J:317692
 
First Author: Wu H
Year: 2021
Journal: Front Pharmacol
Title: Genetic Ablation of the Mitochondrial Calcium Uniporter (MCU) Does not Impair T Cell-Mediated Immunity In Vivo.
Volume: 12
Pages: 734078
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Publication
19342649 | J:147736
First Author: Zimmerli C
Year: 2009
Journal: J Immunol
Title: Adaptive immune response in JAM-C-deficient mice: normal initiation but reduced IgG memory.
Volume: 182
Issue: 8
Pages: 4728-36
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Publication
21183592 | J:185879
First Author: Bothwell SP
Year: 2011
Journal: J Am Soc Nephrol
Title: Mouse model for Lowe syndrome/Dent Disease 2 renal tubulopathy.
Volume: 22
Issue: 3
Pages: 443-8
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Publication
28825721 | J:251029
First Author: Li XX
Year: 2017
Journal: Oncogene
Title: Knockdown of IRE1α inhibits colonic tumorigenesis through decreasing β-catenin and IRE1α targeting suppresses colon cancer cells.
Volume: 36
Issue: 48
Pages: 6738-6746
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Publication
26065429 | J:232960
First Author: Yu H
Year: 2015
Journal: J Cell Sci
Title: Stk40 represses adipogenesis through translational control of CCAAT/enhancer-binding proteins.
Volume: 128
Issue: 15
Pages: 2881-90
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Publication
29167172 | J:281976
First Author: Ren G
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Podocytes exhibit a specialized protein quality control employing derlin-2 in kidney disease.
Volume: 314
Issue: 3
Pages: F471-F482
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Publication
28739879 | J:287656
First Author: Nzoumbou-Boko R
Year: 2017
Journal: J Immunol
Title: Trypanosoma musculi Infection in Mice Critically Relies on Mannose Receptor-Mediated Arginase Induction by a TbKHC1 Kinesin H Chain Homolog.
Volume: 199
Issue: 5
Pages: 1762-1771
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Publication
21977017 | J:262358
 
First Author: Ramanantsoa N
Year: 2011
Journal: Front Physiol
Title: Impaired ventilatory and thermoregulatory responses to hypoxic stress in newborn phox2b heterozygous knock-out mice.
Volume: 2
Pages: 61
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Publication
25340339 | J:232540
First Author: Traboulsi H
Year: 2014
Journal: PLoS Genet
Title: Dynamic partnership between TFIIH, PGC-1α and SIRT1 is impaired in trichothiodystrophy.
Volume: 10
Issue: 10
Pages: e1004732
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Publication
10856830 | J:63068
First Author: Shall S
Year: 2000
Journal: Mutat Res
Title: Poly(ADP-ribose) polymerase-1: what have we learned from the deficient mouse model?
Volume: 460
Issue: 1
Pages: 1-15
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Publication
28993643 | J:254569
First Author: Marrocco J
Year: 2017
Journal: Nat Commun
Title: A sexually dimorphic pre-stressed translational signature in CA3 pyramidal neurons of BDNF Val66Met mice.
Volume: 8
Issue: 1
Pages: 808
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Publication
19299509 | J:149916
First Author: Grimm C
Year: 2009
Journal: J Biol Chem
Title: Life and death of sensory hair cells expressing constitutively active TRPML3.
Volume: 284
Issue: 20
Pages: 13823-31
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Publication
9518481 | J:53869
First Author: Dantzer F
Year: 1998
Journal: Nucleic Acids Res
Title: Functional association of poly(ADP-ribose) polymerase with DNA polymerase alpha-primase complex: a link between DNA strand break detection and DNA replication.
Volume: 26
Issue: 8
Pages: 1891-8
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Publication
27338930 | J:247252
First Author: Raha S
Year: 2016
Journal: Eur J Immunol
Title: Disruption of de novo fatty acid synthesis via acetyl-CoA carboxylase 1 inhibition prevents acute graft-versus-host disease.
Volume: 46
Issue: 9
Pages: 2233-8
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Publication
32845913 | J:295940
First Author: Gong Y
Year: 2020
Journal: PLoS One
Title: Tumor-infiltrating CD62L+PD-1-CD8 T cells retain proliferative potential via Bcl6 expression and replenish effector T cells within the tumor.
Volume: 15
Issue: 8
Pages: e0237646
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Publication
26123823 | J:251645
 
First Author: Lehman SL
Year: 2015
Journal: Sci Rep
Title: Signaling through alternative Integrated Stress Response pathways compensates for GCN2 loss in a mouse model of soft tissue sarcoma.
Volume: 5
Pages: 11781
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Publication
24899640 | J:216246
First Author: Rogon C
Year: 2014
Journal: Mol Biol Cell
Title: HSP70-binding protein HSPBP1 regulates chaperone expression at a posttranslational level and is essential for spermatogenesis.
Volume: 25
Issue: 15
Pages: 2260-71
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Publication
23358455 | J:223057
First Author: Lin C
Year: 2013
Journal: PLoS Genet
Title: Delineating a conserved genetic cassette promoting outgrowth of body appendages.
Volume: 9
Issue: 1
Pages: e1003231
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Publication
19196952 | J:149786
First Author: Hernández Vallejo SJ
Year: 2009
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