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Search results 101 to 199 out of 199 for Vps33b

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Type Details Score
Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
23918659 | J:203128
First Author: Tornieri K
Year: 2013
Journal: Hum Mol Genet
Title: Vps33b pathogenic mutations preferentially affect VIPAS39/SPE-39-positive endosomes.
Volume: 22
Issue: 25
Pages: 5215-28
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Protein Coding Gene
MGI:2144805 | Vipas39
Type: protein_coding_gene
Organism: mouse, laboratory
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HT Experiment
E-GEOD-83192 | Liver tissue from liver specific Vps33b knockout (Vps33bfl/fl-AlfpCre) and control (Vps33bfl/fl) mice
Series Id: GSE83192
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Gene
490808 | VIPAS39
Type: gene
Organism: dog, domestic
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Gene
681989 | Vipas39
Type: gene
Organism: rat
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Gene
453069 | VIPAS39
Type: gene
Organism: chimpanzee
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Gene
508872 | VIPAS39
Type: gene
Organism: cattle
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Gene
423377 | VIPAS39
Type: gene
Organism: chicken
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Gene
415096 | vipas39
Type: gene
Organism: zebrafish
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Gene
706315 | VIPAS39
Type: gene
Organism: macaque, rhesus
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Gene
100145706 | vipas39
Type: gene
Organism: frog, western clawed
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Gene
734344 | vipas39.L
Type: gene
Organism: frog, African clawed
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Allele
Vipas39<tm1c(KOMP)Mbp> | MGI:5816979
Name: VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog; targeted mutation 1c, Mouse Biology Program, UC Davis
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Vipas39<+> | MGI:4437851
 
Name: VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog; wild type
Allele Type: Not Specified
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Allele
Vipas39<tm1(KOMP)Vlcg> | MGI:4881322
Name: VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog; targeted mutation 1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Vipas39<Gt(CSI697)Byg> | MGI:3880260
 
Name: VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog; gene trap CSI697, BayGenomics
Allele Type: Gene trapped
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Allele
Vipas39<Gt(OST10101)Lex> | MGI:4137501
 
Name: VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog; gene trap OST10101, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Vipas39<Gt(OST240479)Lex> | MGI:4246659
 
Name: VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog; gene trap OST240479, Lexicon Genetics
Allele Type: Gene trapped
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Genotype
Genotype
Symbol: Vipas39/Vipas39 Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: C57BL/6 * C57BL/6J * C57BL/6N
Zygosity: cn
Has Mutant Allele: true
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Protein Coding Gene
MGP_CAROLIEiJ_G0017990 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0019983 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0019941 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0019916 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0019920 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0019726 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2144805 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0020372 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0019276 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0019698 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0019811 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0019798 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0019885 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0019837 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0020404 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0019040 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0019329 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0029749 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0018835 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
 
Probe: MGI:3584634
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:3585330
Age: embryonic day 18.0
Note: Expression was detected in the inner neuroblastic layer.
Specimen Label: E18
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3584634
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3585330
Age: postnatal day 0-1
Image: P0/1
Note: Expression was detected in the inner neuroblastic layer.
Specimen Label: P0/1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:3584634
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3585330
Age: postnatal day 2-3
Note: Expression was detected in the inner neuroblastic layer.
Specimen Label: P2/3
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:3584634
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585330
Age: postnatal day 6-7
Image: P6/7
Specimen Label: P6/7
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:3584634
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585330
Age: postnatal day 8-10
Image: P8/10
Specimen Label: P8/10
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:3584634
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585330
Age: postnatal adult
Image: Adult
Specimen Label: Adult
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:3584634
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598824
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3585330
Age: embryonic day 16.0
Specimen Label: Embryo
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:3584634
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1647028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585330
Age: postnatal day 6
Note: Expression was widespread.
Specimen Label: CNS
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:3584634
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603924
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3585330
Age: embryonic day 16.0
Note: Expression was widespread.
Specimen Label: Embryo
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:3584634
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915726
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:3585330
Age: embryonic day 18.0
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: E18
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3584634
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3585330
Age: postnatal day 0-1
Image: P0/1
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P0/1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:3584634
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1915727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3585330
Age: postnatal day 2-3
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P2/3
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:3584634
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3585330
Age: postnatal day 4-5
Note: Expression was detected in the vitreal outer neuroblastic layer.
Specimen Label: P4/5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:3584634
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585330
Age: postnatal adult
Image: Adult
Specimen Label: Adult
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:3584634
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1859224
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:3585330
Age: embryonic day 16.0
Note: Expression was detected in the inner and outer neuroblastic layer. The expression was higher in the inner layer.
Specimen Label: E16
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:3584634
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3574228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3585330
Age: postnatal day 6-7
Image: P6/7
Note: Expression was detected in amacrine cells.
Specimen Label: P6/7
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:3584634
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3574228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3585330
Age: postnatal day 8-10
Image: P8/10
Note: Expression was detected in amacrine cells.
Specimen Label: P8/10
Detected: true
Specimen Num: 7
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Allele
Vipas39<tm1e(KOMP)Mbp> | MGI:4840844
Name: VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog; targeted mutation 1e, Mouse Biology Program, UC Davis
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Vipas39<Gt(IST12430C11)Tigm> | MGI:4078257
 
Name: VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog; gene trap IST12430C11, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Vipas39<tm1a(KOMP)Mbp> | MGI:4840775
Name: VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog; targeted mutation 1a, Mouse Biology Program, UC Davis
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Vipas39<Gt(XS0879)Wtsi> | MGI:4331868
 
Name: VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog; gene trap XS0879, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Vipas39<Gt(AC0572)Wtsi> | MGI:4344567
 
Name: VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog; gene trap AC0572, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Vipas39<Gt(PST1343)Mfgc> | MGI:4122409
 
Name: VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog; gene trap PST1343, Mammalian Functional Genomics Centre
Allele Type: Gene trapped
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Allele
Vipas39<Gt(E125F08)Wrst> | MGI:3909465
 
Name: VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog; gene trap E125F08, German Gene Trap Consortium
Allele Type: Gene trapped
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Allele
Vipas39<Gt(EUCE0083a02)Hmgu> | MGI:4379436
 
Name: VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog; gene trap EUCE0083a02, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Vipas39<Gt(XS0066)Wtsi> | MGI:3877263
 
Name: VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog; gene trap XS0066, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Vipas39<Gt(CC0685)Wtsi> | MGI:3870382
 
Name: VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog; gene trap CC0685, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Vipas39<Gt(E203B01)Wrst> | MGI:3918375
 
Name: VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog; gene trap E203B01, German Gene Trap Consortium
Allele Type: Gene trapped
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DO Term
DOID:0111353 | arthrogryposis, renal dysfunction, and cholestasis 1
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Allele
Vps33b<tm1.1Arte> | MGI:5770088
Name: vacuolar protein sorting 33B; targeted mutation 1.1, TaconicArtemis
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Protein Domain
IPR027121 | VPS33
Type: Family
Description: Vacuolar protein sorting-associated protein 33 (Vps33) is essential for vacuolar biogenesis, maturation and function. It is involved in the sorting of vacuolar proteins from the Golgi apparatus and their targeting to the vacuole []. In worm, fly, zebrafish and mammals two homologues of yeast Vps33p have been detected (termed VPS33A and VPS33B in humans). These homologues may reflect the evolution of organelle/tissue-specific functions in multicellular organisms. It is thought that VPS33B may be required for transport to conventional lysosomes, while VPS33A is mainly involved in biogenesis of melanosomes and related lysosomal compartments [, ].
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Genotype
Genotype
Symbol: Vps33b/Vps33b Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: C57BL/6 * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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DO Term
DOID:0050763 | ARC syndrome
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Publication
12538872 | J:81830
First Author: Suzuki T
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: The mouse organellar biogenesis mutant buff results from a mutation in Vps33a, a homologue of yeast vps33 and Drosophila carnation.
Volume: 100
Issue: 3
Pages: 1146-50
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Publication
12868054 | -
First Author: Iwaki T
Year: 2003
Journal: Yeast
Title: Characterization of vps33+, a gene required for vacuolar biogenesis and protein sorting in Schizosaccharomyces pombe.
Volume: 20
Issue: 10
Pages: 845-55
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Publication
10894945 | J:63246
First Author: Carim L
Year: 2000
Journal: Cytogenet Cell Genet
Title: Cloning, mapping and expression analysis of VPS33B, the human orthologue of rat Vps33b.
Volume: 89
Issue: 1-2
Pages: 92-5
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Protein Domain
IPR043155 | VPS33_dom3b
Type: Homologous_superfamily
Description: Members of the Sec1 family include Sec1, Sly1, Slp1/Vps33, Vps45/Stt10 (yeast), Unc-18 (nematode), Munc-18b/muSec1, Munc-18c (mouse), Rop (Drosophila), Munc-18/n-Sec1/rbSec1A and rbSec1B (rat) [].The nSec1 polypeptide chain can be divided into three domains. The first domain, consists of a five-stranded parallel β-sheet flanked by five α-helices. The second domain, like the first one, has an α-β-alpha fold, however the β-sheet of domain 2 features five parallel strands with an additional antiparallel strand on one edge. The third domain is a large insertion between the third and fourth parallel strands of domain 2, and can be subdivided in two [].Vacuolar protein sorting-associated protein 33 (Vps33) is essential for vacuolar biogenesis, maturation and function. It is involved in the sorting of vacuolar proteins from the Golgi apparatus and their targeting to the vacuole []. In worm, fly, zebrafish and mammals two homologues of yeast Vps33p have been detected (termed VPS33A and VPS33B in humans). These homologues may reflect the evolution of organelle/tissue-specific functions in multicellular organisms. It is thought that VPS33B may be required for transport to conventional lysosomes, while VPS33A is mainly involved in biogenesis of melanosomes and related lysosomal compartments [, ].This superfamily entry represents the C-terminal region of domain 3 (called domain 3b) found in VPS33.
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Protein
Q9D2N9
Organism: Mus musculus/domesticus
Length: 598  
Fragment?: false
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Protein
Q80XK7
Organism: Mus musculus/domesticus
Length: 598  
Fragment?: false
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Publication
19109425 | J:159132
First Author: Zhu GD
Year: 2009
Journal: Mol Biol Cell
Title: SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery.
Volume: 20
Issue: 4
Pages: 1223-40
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Publication
23861251 | J:203707
First Author: Kahr WH
Year: 2013
Journal: Blood
Title: Abnormal megakaryocyte development and platelet function in Nbeal2(-/-) mice.
Volume: 122
Issue: 19
Pages: 3349-58
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Protein
A0A0U1RPK8
Organism: Mus musculus/domesticus
Length: 104  
Fragment?: true
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Protein
S4R1H4
Organism: Mus musculus/domesticus
Length: 143  
Fragment?: false
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Protein
P59016
Organism: Mus musculus/domesticus
Length: 617  
Fragment?: false
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Protein
Q8C076
Organism: Mus musculus/domesticus
Length: 617  
Fragment?: false
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Publication
8769846 | J:31434
First Author: Halachmi N
Year: 1996
Journal: J Neurochem
Title: The Sec1 family: a novel family of proteins involved in synaptic transmission and general secretion.
Volume: 66
Issue: 3
Pages: 889-97
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Publication
10746715 | -
First Author: Misura KM
Year: 2000
Journal: Nature
Title: Three-dimensional structure of the neuronal-Sec1-syntaxin 1a complex.
Volume: 404
Issue: 6776
Pages: 355-62
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Publication
- | J:157064
     
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
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Publication
15226823 | J:93300
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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