This entry represents the DEAD-box helicase domain found in DDX47 from animals and Rrp3 from yeasts. This domain contains the ATP-binding region. Rrp3 is involved in rRNA processing []. DDX47 (also called E4-DEAD box protein) can shuttle between the nucleus and the cytoplasm, and has an RNA-independent ATPase activity [, ].
This entry represents the RNA recognition motif of NOP8 (also known as NOP132). In humans, NOP132 associates with proteins involved in ribosome biogenesis and RNA metabolism, including the DEAD-box RNA helicase protein, DDX47 []. Budding yeast NOP8 is required for 60S ribosomal subunit synthesis [].
