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Search results 1 to 100 out of 841 for Vldlr

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rabbit, European
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Protein Domain
Type: Family
Description: Very low-density lipoprotein receptor (VLDLR) mediates the binding and uptake of apoE-containing lipoproteins, such as VLDL and beta-VLDL []. It prevents the migration of retinal vascular endothelial cells into the photoreceptor cell layer and subretinal space []and mediates an anti-angiogenic signal in the retina []. It is involved in adipose tissue inflammation and mediates VLDL-induced lipid accumulation and induction of inflammation and ER stress in adipocytes and macrophages [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Xia CH
Year: 2013
Journal: PLoS One
Title: Deletion of LRP5 in VLDLR knockout mice inhibits retinal neovascularization.
Volume: 8
Issue: 9
Pages: e75186
Gene
Type: gene
Organism: human
Publication
First Author: Nguyen A
Year: 2014
Journal: J Biol Chem
Title: Very low density lipoprotein receptor (VLDLR) expression is a determinant factor in adipose tissue inflammation and adipocyte-macrophage interaction.
Volume: 289
Issue: 3
Pages: 1688-703
Publication
First Author: Jiang A
Year: 2009
Journal: Invest Ophthalmol Vis Sci
Title: Loss of VLDL receptor activates retinal vascular endothelial cells and promotes angiogenesis.
Volume: 50
Issue: 2
Pages: 844-50
Protein
Organism: Mus musculus/domesticus
Length: 873  
Fragment?: false
Publication
First Author: Shin KC
Year: 2017
Journal: Nat Commun
Title: Macrophage VLDLR mediates obesity-induced insulin resistance with adipose tissue inflammation.
Volume: 8
Issue: 1
Pages: 1087
Publication
First Author: Xia CH
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: The role of Vldlr in intraretinal angiogenesis in mice.
Volume: 52
Issue: 9
Pages: 6572-9
Publication
First Author: Huynh H
Year: 2017
Journal: Cell Rep
Title: mTOR Inhibition Subdues Milk Disorder Caused by Maternal VLDLR Loss.
Volume: 19
Issue: 10
Pages: 2014-2025
Publication
First Author: Zhao S
Year: 2007
Journal: Dev Dyn
Title: Selective expression of LDLR and VLDLR in myelinating oligodendrocytes.
Volume: 236
Issue: 9
Pages: 2708-12
Publication
First Author: Rebustini IT
Year: 2012
Journal: Development
Title: miR-200c regulates FGFR-dependent epithelial proliferation via Vldlr during submandibular gland branching morphogenesis.
Volume: 139
Issue: 1
Pages: 191-202
Publication
First Author: Barr AM
Year: 2007
Journal: Neuropharmacology
Title: The reelin receptors VLDLR and ApoER2 regulate sensorimotor gating in mice.
Volume: 52
Issue: 4
Pages: 1114-23
Publication
First Author: Hack I
Year: 2007
Journal: Development
Title: Divergent roles of ApoER2 and Vldlr in the migration of cortical neurons.
Volume: 134
Issue: 21
Pages: 3883-91
Publication  
First Author: Fraley ER
Year: 2016
Journal: Sci Rep
Title: Mice with Dab1 or Vldlr insufficiency exhibit abnormal neonatal vocalization patterns.
Volume: 6
Pages: 25807
Publication  
First Author: Su J
Year: 2013
Journal: Neural Dev
Title: Contributions of VLDLR and LRP8 in the establishment of retinogeniculate projections.
Volume: 8
Pages: 11
Publication
First Author: Augustin M
Year: 2016
Journal: PLoS One
Title: Multi-Functional OCT Enables Longitudinal Study of Retinal Changes in a VLDLR Knockout Mouse Model.
Volume: 11
Issue: 10
Pages: e0164419
Publication  
First Author: Hirota Y
Year: 2020
Journal: Development
Title: VLDLR is not essential for reelin-induced neuronal aggregation but suppresses neuronal invasion into the marginal zone.
Volume: 147
Issue: 12
Protein
Organism: Mus musculus/domesticus
Length: 258  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 721  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 498  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 89  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 804  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 845  
Fragment?: false
Publication
First Author: Takahashi S
Year: 2003
Journal: Mol Cell Biochem
Title: The very low density lipoprotein (VLDL) receptor--a peripheral lipoprotein receptor for remnant lipoproteins into fatty acid active tissues.
Volume: 248
Issue: 1-2
Pages: 121-7
Publication
First Author: Roubtsova A
Year: 2011
Journal: Arterioscler Thromb Vasc Biol
Title: Circulating proprotein convertase subtilisin/kexin 9 (PCSK9) regulates VLDLR protein and triglyceride accumulation in visceral adipose tissue.
Volume: 31
Issue: 4
Pages: 785-91
Publication  
First Author: Dumanis SB
Year: 2012
Journal: Mol Neurodegener
Title: FE65 as a link between VLDLR and APP to regulate their trafficking and processing.
Volume: 7
Pages: 9
Publication
First Author: Hirota Y
Year: 2015
Journal: J Comp Neurol
Title: Reelin receptors ApoER2 and VLDLR are expressed in distinct spatiotemporal patterns in developing mouse cerebral cortex.
Volume: 523
Issue: 3
Pages: 463-78
Publication
First Author: Zhou X
Year: 2011
Journal: PLoS One
Title: Nanoceria inhibit the development and promote the regression of pathologic retinal neovascularization in the Vldlr knockout mouse.
Volume: 6
Issue: 2
Pages: e16733
Publication
First Author: Yakovlev S
Year: 2012
Journal: Blood
Title: Identification of VLDLR as a novel endothelial cell receptor for fibrin that modulates fibrin-dependent transendothelial migration of leukocytes.
Volume: 119
Issue: 2
Pages: 637-44
Publication
First Author: Johnson V
Year: 2015
Journal: PLoS One
Title: Neurite Mistargeting and Inverse Order of Intraretinal Vascular Plexus Formation Precede Subretinal Vascularization in Vldlr Mutant Mice.
Volume: 10
Issue: 7
Pages: e0132013
Publication
First Author: Larouche M
Year: 2008
Journal: PLoS One
Title: The Reelin receptors Apoer2 and Vldlr coordinate the patterning of Purkinje cell topography in the developing mouse cerebellum.
Volume: 3
Issue: 2
Pages: e1653
Publication  
First Author: Sakai K
Year: 2009
Journal: Brain Res
Title: A neuronal VLDLR variant lacking the third complement-type repeat exhibits high capacity binding of apoE containing lipoproteins.
Volume: 1276
Pages: 11-21
Publication
First Author: Sharaf A
Year: 2013
Journal: PLoS One
Title: ApoER2 and VLDLr are required for mediating reelin signalling pathway for normal migration and positioning of mesencephalic dopaminergic neurons.
Volume: 8
Issue: 8
Pages: e71091
Publication
First Author: Hu W
Year: 2008
Journal: Invest Ophthalmol Vis Sci
Title: Expression of VLDLR in the retina and evolution of subretinal neovascularization in the knockout mouse model's retinal angiomatous proliferation.
Volume: 49
Issue: 1
Pages: 407-15
Publication
First Author: Schnaufer C
Year: 2009
Journal: Cell Tissue Res
Title: Outgrowing olfactory axons contain the Reelin receptor VLDLR and navigate through the Reelin-rich cribriform mesenchyme.
Volume: 337
Issue: 3
Pages: 393-406
Publication  
First Author: Kyosseva SV
Year: 2013
Journal: Exp Eye Res
Title: Nanoceria inhibit expression of genes associated with inflammation and angiogenesis in the retina of Vldlr null mice.
Volume: 116
Pages: 63-74
Publication
First Author: Luque JM
Year: 2003
Journal: Brain Res Dev Brain Res
Title: Localization of ApoER2, VLDLR and Dab1 in radial glia: groundwork for a new model of reelin action during cortical development.
Volume: 140
Issue: 2
Pages: 195-203
HT Experiment
Series Id: GSE78831
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication      
First Author: Ufret-Vincenty R
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for spotty.
Publication
First Author: Trommsdorff M
Year: 1999
Journal: Cell
Title: Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2.
Volume: 97
Issue: 6
Pages: 689-701
Publication
First Author: Ma X
Year: 2024
Journal: Commun Biol
Title: Deficient RPE mitochondrial energetics leads to subretinal fibrosis in age-related neovascular macular degeneration.
Volume: 7
Issue: 1
Pages: 1075
Publication
First Author: Bovenschen N
Year: 2004
Journal: Br J Haematol
Title: Clearance of coagulation factor VIII in very low-density lipoprotein receptor knockout mice.
Volume: 126
Issue: 5
Pages: 722-5
Publication
First Author: Fredriksson K
Year: 2014
Journal: J Immunol
Title: The very low density lipoprotein receptor attenuates house dust mite-induced airway inflammation by suppressing dendritic cell-mediated adaptive immune responses.
Volume: 192
Issue: 10
Pages: 4497-509
Publication
First Author: Oshio Y
Year: 2021
Journal: Sci Rep
Title: Very low-density lipoprotein receptor increases in a liver-specific manner due to protein deficiency but does not affect fatty liver in mice.
Volume: 11
Issue: 1
Pages: 8003
Publication
First Author: Li C
Year: 2007
Journal: Arch Ophthalmol
Title: Biochemical alterations in the retinas of very low-density lipoprotein receptor knockout mice: an animal model of retinal angiomatous proliferation.
Volume: 125
Issue: 6
Pages: 795-803
Publication
First Author: Goudriaan JR
Year: 2004
Journal: J Lipid Res
Title: The VLDL receptor plays a major role in chylomicron metabolism by enhancing LPL-mediated triglyceride hydrolysis.
Volume: 45
Issue: 8
Pages: 1475-81
Publication
First Author: Chen Y
Year: 2007
Journal: J Biol Chem
Title: Very low density lipoprotein receptor, a negative regulator of the wnt signaling pathway and choroidal neovascularization.
Volume: 282
Issue: 47
Pages: 34420-8
Publication
First Author: Heckenlively JR
Year: 2003
Journal: Retina
Title: Mouse model of subretinal neovascularization with choroidal anastomosis.
Volume: 23
Issue: 4
Pages: 518-22
Publication
First Author: Perman JC
Year: 2011
Journal: J Clin Invest
Title: The VLDL receptor promotes lipotoxicity and increases mortality in mice following an acute myocardial infarction.
Volume: 121
Issue: 7
Pages: 2625-40
Publication
First Author: Tao H
Year: 2011
Journal: Biochem Pharmacol
Title: Very low density lipoprotein receptor promotes adipocyte differentiation and mediates the proadipogenic effect of peroxisome proliferator-activated receptor gamma agonists.
Volume: 82
Issue: 12
Pages: 1950-62
Publication
First Author: Hiesberger T
Year: 1999
Journal: Neuron
Title: Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation.
Volume: 24
Issue: 2
Pages: 481-9
Publication
First Author: Oka K
Year: 1994
Journal: Eur J Biochem
Title: Mouse very-low-density-lipoprotein receptor (VLDLR) cDNA cloning, tissue-specific expression and evolutionary relationship with the low-density-lipoprotein receptor.
Volume: 224
Issue: 3
Pages: 975-82
Publication
First Author: Weiss KH
Year: 2003
Journal: J Comp Neurol
Title: Malformation of the radial glial scaffold in the dentate gyrus of reeler mice, scrambler mice, and ApoER2/VLDLR-deficient mice.
Volume: 460
Issue: 1
Pages: 56-65
Publication
First Author: Yagyu H
Year: 2002
Journal: J Biol Chem
Title: Very low density lipoprotein (VLDL) receptor-deficient mice have reduced lipoprotein lipase activity. Possible causes of hypertriglyceridemia and reduced body mass with VLDL receptor deficiency.
Volume: 277
Issue: 12
Pages: 10037-43
Publication
First Author: Goudriaan JR
Year: 2001
Journal: Arterioscler Thromb Vasc Biol
Title: Protection from obesity in mice lacking the VLDL receptor.
Volume: 21
Issue: 9
Pages: 1488-93
Publication
First Author: Shao Y
Year: 2019
Journal: Stem Cells
Title: Canonical Wnt Signaling Promotes Neovascularization Through Determination of Endothelial Progenitor Cell Fate via Metabolic Profile Regulation.
Volume: 37
Issue: 10
Pages: 1331-1343
Publication
First Author: Qiao L
Year: 2008
Journal: Diabetes
Title: Adiponectin reduces plasma triglyceride by increasing VLDL triglyceride catabolism.
Volume: 57
Issue: 7
Pages: 1824-33
Publication
First Author: Zhang G
Year: 2007
Journal: PLoS One
Title: The Pafah1b complex interacts with the reelin receptor VLDLR.
Volume: 2
Issue: 2
Pages: e252
Publication
First Author: Assadi AH
Year: 2003
Journal: Nat Genet
Title: Interaction of reelin signaling and Lis1 in brain development.
Volume: 35
Issue: 3
Pages: 270-6
Publication
First Author: Blake SM
Year: 2008
Journal: EMBO J
Title: Thrombospondin-1 binds to ApoER2 and VLDL receptor and functions in postnatal neuronal migration.
Volume: 27
Issue: 22
Pages: 3069-80
Publication
First Author: Yang X
Year: 2022
Journal: Immunity
Title: Very-low-density lipoprotein receptor-enhanced lipid metabolism in pancreatic stellate cells promotes pancreatic fibrosis.
Volume: 55
Issue: 7
Pages: 1185-1199.e8
Publication
First Author: Shan L
Year: 2008
Journal: Biochem Biophys Res Commun
Title: PCSK9 binds to multiple receptors and can be functionally inhibited by an EGF-A peptide.
Volume: 375
Issue: 1
Pages: 69-73
Publication
First Author: Hellwig S
Year: 2012
Journal: PLoS One
Title: Reelin together with ApoER2 regulates interneuron migration in the olfactory bulb.
Volume: 7
Issue: 11
Pages: e50646
Publication
First Author: Trotter JH
Year: 2011
Journal: J Neurosci
Title: ApoER2 function in the establishment and maintenance of retinal synaptic connectivity.
Volume: 31
Issue: 40
Pages: 14413-23
Publication
First Author: Tao H
Year: 2010
Journal: Am J Physiol Endocrinol Metab
Title: Peroxisome proliferator-activated receptor-gamma regulates the expression and function of very-low-density lipoprotein receptor.
Volume: 298
Issue: 1
Pages: E68-79
Publication
First Author: Tacken PJ
Year: 2000
Journal: J Lipid Res
Title: LDL receptor deficiency unmasks altered VLDL triglyceride metabolism in VLDL receptor transgenic and knockout mice.
Volume: 41
Issue: 12
Pages: 2055-62
Publication
First Author: Ma X
Year: 2021
Journal: J Biol Chem
Title: ADAM17 mediates ectodomain shedding of the soluble VLDL receptor fragment in the retinal epithelium.
Volume: 297
Issue: 4
Pages: 101185
Publication
First Author: Akopians AL
Year: 2008
Journal: Eur J Neurosci
Title: Contribution of the Reelin signaling pathways to nociceptive processing.
Volume: 27
Issue: 3
Pages: 523-37
Publication
First Author: Jakob B
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Intersectin 1 is a component of the Reelin pathway to regulate neuronal migration and synaptic plasticity in the hippocampus.
Volume: 114
Issue: 21
Pages: 5533-5538
Publication
First Author: Chen Q
Year: 2016
Journal: Mol Cell Biol
Title: Functional Differences of Very-Low-Density Lipoprotein Receptor Splice Variants in Regulating Wnt Signaling.
Volume: 36
Issue: 20
Pages: 2645-54
Publication
First Author: DiBattista AM
Year: 2015
Journal: Biochim Biophys Acta
Title: Very low density lipoprotein receptor regulates dendritic spine formation in a RasGRF1/CaMKII dependent manner.
Volume: 1853
Issue: 5
Pages: 904-17
Publication
First Author: Yip YP
Year: 2004
Journal: J Comp Neurol
Title: Components of the reelin signaling pathway are expressed in the spinal cord.
Volume: 470
Issue: 2
Pages: 210-9
Publication
First Author: Perez-Garcia CG
Year: 2004
Journal: Eur J Neurosci
Title: Reelin receptors in developing laminated brain structures of mouse and human.
Volume: 20
Issue: 10
Pages: 2827-32
Publication
First Author: Ha S
Year: 2017
Journal: J Neurosci
Title: C-Terminal Region Truncation of RELN Disrupts an Interaction with VLDLR, Causing Abnormal Development of the Cerebral Cortex and Hippocampus.
Volume: 37
Issue: 4
Pages: 960-971
Publication
First Author: Pilz A
Year: 1995
Journal: Genomics
Title: Comparative mapping of 50 human chromosome 9 loci in the laboratory mouse.
Volume: 25
Issue: 1
Pages: 139-49
Publication  
First Author: Jong MC
Year: 1999
Journal: Biochem J
Title: Reversal of hyperlipidaemia in apolipoprotein C1 transgenic mice by adenovirus-mediated gene delivery of the low-density-lipoprotein receptor, but not by the very-low-density-lipoprotein receptor.
Volume: 338 ( Pt 2)
Pages: 281-7
Publication
First Author: Kobayashi K
Year: 1996
Journal: J Biol Chem
Title: Reversal of hypercholesterolemia in low density lipoprotein receptor knockout mice by adenovirus-mediated gene transfer of the very low density lipoprotein receptor.
Volume: 271
Issue: 12
Pages: 6852-60
Publication
First Author: Deane R
Year: 2008
Journal: J Clin Invest
Title: apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain.
Volume: 118
Issue: 12
Pages: 4002-13
Publication
First Author: van der Hoogt CC
Year: 2006
Journal: Biochim Biophys Acta
Title: Apolipoprotein CI causes hypertriglyceridemia independent of the very-low-density lipoprotein receptor and apolipoprotein CIII in mice.
Volume: 1761
Issue: 2
Pages: 213-20
Publication
First Author: Andrade N
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: ApoER2/VLDL receptor and Dab1 in the rostral migratory stream function in postnatal neuronal migration independently of Reelin.
Volume: 104
Issue: 20
Pages: 8508-13
Publication
First Author: Herrick TM
Year: 2004
Journal: Brain Res Mol Brain Res
Title: High affinity binding of Dab1 to Reelin receptors promotes normal positioning of upper layer cortical plate neurons.
Volume: 126
Issue: 2
Pages: 121-8
Publication
First Author: Gåfvels ME
Year: 1994
Journal: Endocrinology
Title: Cloning of a complementary deoxyribonucleic acid encoding the murine homolog of the very low density lipoprotein/apolipoprotein-E receptor: expression pattern and assignment of the gene to mouse chromosome 19.
Volume: 135
Issue: 1
Pages: 387-94
Publication
First Author: Xiao X
Year: 2020
Journal: Int J Biol Sci
Title: ROBO4 deletion ameliorates PAF-mediated skin inflammation via regulating the mRNA translation efficiency of LPCAT1/LPCAT2 and the expression of PAF receptor.
Volume: 16
Issue: 6
Pages: 1086-1095
Publication
First Author: Kohno T
Year: 2020
Journal: J Neurosci
Title: Reelin-Nrp1 Interaction Regulates Neocortical Dendrite Development in a Context-Specific Manner.
Volume: 40
Issue: 43
Pages: 8248-8261
Publication
First Author: Bock HH
Year: 2003
Journal: Curr Biol
Title: Reelin activates SRC family tyrosine kinases in neurons.
Volume: 13
Issue: 1
Pages: 18-26
Publication
First Author: Sharaf A
Year: 2015
Journal: Cell Tissue Res
Title: Localization of reelin signaling pathway components in murine midbrain and striatum.
Volume: 359
Issue: 2
Pages: 393-407
Publication
First Author: Tiebel O
Year: 1999
Journal: Atherosclerosis
Title: Mouse very low-density lipoprotein receptor (VLDLR): gene structure, tissue-specific expression and dietary and developmental regulation.
Volume: 145
Issue: 2
Pages: 239-51
Publication  
First Author: Dairaghi L
Year: 2018
Journal: Front Cell Neurosci
Title: Reelin Can Modulate Migration of Olfactory Ensheathing Cells and Gonadotropin Releasing Hormone Neurons via the Canonical Pathway.
Volume: 12
Pages: 228
Publication
First Author: Sentürk A
Year: 2011
Journal: Nature
Title: Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration.
Volume: 472
Issue: 7343
Pages: 356-60