|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 200 out of 4877 for Nlrp3

0.039s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Publication
First Author: Sokolova M
Year: 2018
Journal: Am J Physiol Endocrinol Metab
Title: NLRP3 inflammasome mediates oxidative stress-induced pancreatic islet dysfunction.
Volume: 315
Issue: 5
Pages: E912-E923
Publication  
First Author: Ma H
Year: 2021
Journal: Front Immunol
Title: NLRP3 Inflammasome Contributes to Host Defense Against Talaromyces marneffei Infection.
Volume: 12
Pages: 760095
Publication
First Author: Suresh R
Year: 2016
Journal: J Cell Sci
Title: Complement-mediated 'bystander' damage initiates host NLRP3 inflammasome activation.
Volume: 129
Issue: 9
Pages: 1928-39
Publication
First Author: Sandanger Ø
Year: 2016
Journal: Biochem Biophys Res Commun
Title: NLRP3 inflammasome activation during myocardial ischemia reperfusion is cardioprotective.
Volume: 469
Issue: 4
Pages: 1012-20
Publication
First Author: Zhang L
Year: 2021
Journal: Cell Rep
Title: Peli1 facilitates NLRP3 inflammasome activation by mediating ASC ubiquitination.
Volume: 37
Issue: 4
Pages: 109904
Publication
First Author: Kim S
Year: 2010
Journal: Eur J Immunol
Title: Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome.
Volume: 40
Issue: 6
Pages: 1545-51
Publication
First Author: Karki R
Year: 2020
Journal: J Immunol
Title: IRF8 Regulates Gram-Negative Bacteria-Mediated NLRP3 Inflammasome Activation and Cell Death.
Volume: 204
Issue: 9
Pages: 2514-2522
Publication
First Author: Hooftman A
Year: 2020
Journal: Cell Metab
Title: The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation.
Volume: 32
Issue: 3
Pages: 468-478.e7
Publication  
First Author: Yang CS
Year: 2015
Journal: Nat Commun
Title: Small heterodimer partner interacts with NLRP3 and negatively regulates activation of the NLRP3 inflammasome.
Volume: 6
Pages: 6115
Publication
First Author: Yao X
Year: 2017
Journal: Nat Commun
Title: Remodelling of the gut microbiota by hyperactive NLRP3 induces regulatory T cells to maintain homeostasis.
Volume: 8
Issue: 1
Pages: 1896
Publication
First Author: Kalbitz M
Year: 2016
Journal: FASEB J
Title: Complement-induced activation of the cardiac NLRP3 inflammasome in sepsis.
Volume: 30
Issue: 12
Pages: 3997-4006
Publication
First Author: Xie K
Year: 2020
Journal: Inflamm Res
Title: Hydrogen attenuates sepsis-associated encephalopathy by NRF2 mediated NLRP3 pathway inactivation.
Volume: 69
Issue: 7
Pages: 697-710
Publication
First Author: Bruchard M
Year: 2015
Journal: Nat Immunol
Title: The receptor NLRP3 is a transcriptional regulator of TH2 differentiation.
Volume: 16
Issue: 8
Pages: 859-70
Publication
First Author: Daley D
Year: 2017
Journal: J Exp Med
Title: NLRP3 signaling drives macrophage-induced adaptive immune suppression in pancreatic carcinoma.
Volume: 214
Issue: 6
Pages: 1711-1724
Publication
First Author: Mayes-Hopfinger L
Year: 2021
Journal: Nat Commun
Title: Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis.
Volume: 12
Issue: 1
Pages: 4546
Publication
First Author: Allam R
Year: 2013
Journal: Eur J Immunol
Title: Histones trigger sterile inflammation by activating the NLRP3 inflammasome.
Volume: 43
Issue: 12
Pages: 3336-42
Publication
First Author: Gong T
Year: 2017
Journal: J Immunol
Title: Plant Lectins Activate the NLRP3 Inflammasome To Promote Inflammatory Disorders.
Volume: 198
Issue: 5
Pages: 2082-2092
Publication
First Author: Park YJ
Year: 2023
Journal: EMBO J
Title: MARCH5-dependent NLRP3 ubiquitination is required for mitochondrial NLRP3-NEK7 complex formation and NLRP3 inflammasome activation.
Volume: 42
Issue: 19
Pages: e113481
Publication
First Author: Youm YH
Year: 2015
Journal: Nat Med
Title: The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.
Volume: 21
Issue: 3
Pages: 263-9
Publication
First Author: Embry CA
Year: 2011
Journal: Sci Signal
Title: Mechanism of impaired NLRP3 inflammasome priming by monophosphoryl lipid A.
Volume: 4
Issue: 171
Pages: ra28
Publication
First Author: Moon JS
Year: 2015
Journal: J Clin Invest
Title: UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis.
Volume: 125
Issue: 2
Pages: 665-80
Publication
First Author: Rühl S
Year: 2015
Journal: Eur J Immunol
Title: Caspase-11 activates a canonical NLRP3 inflammasome by promoting K(+) efflux.
Volume: 45
Issue: 10
Pages: 2927-36
Publication
First Author: Gurung P
Year: 2015
Journal: J Clin Invest
Title: An NLRP3 inflammasome-triggered Th2-biased adaptive immune response promotes leishmaniasis.
Volume: 125
Issue: 3
Pages: 1329-38
Publication
First Author: Faro J
Year: 2019
Journal: Biol Reprod
Title: Intra-amniotic inflammation induces preterm birth by activating the NLRP3 inflammasome†.
Volume: 100
Issue: 5
Pages: 1290-1305
Publication
First Author: Tumurkhuu G
Year: 2016
Journal: Circ Res
Title: Ogg1-Dependent DNA Repair Regulates NLRP3 Inflammasome and Prevents Atherosclerosis.
Volume: 119
Issue: 6
Pages: e76-90
Publication
First Author: Brydges SD
Year: 2013
Journal: J Clin Invest
Title: Divergence of IL-1, IL-18, and cell death in NLRP3 inflammasomopathies.
Volume: 123
Issue: 11
Pages: 4695-705
Publication
First Author: Place DE
Year: 2018
Journal: Am J Pathol
Title: ASK Family Kinases Are Required for Optimal NLRP3 Inflammasome Priming.
Volume: 188
Issue: 4
Pages: 1021-1030
Publication
First Author: Antonopoulos C
Year: 2015
Journal: J Biol Chem
Title: Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome Signaling.
Volume: 290
Issue: 33
Pages: 20167-84
Publication
First Author: Wynosky-Dolfi MA
Year: 2014
Journal: J Exp Med
Title: Oxidative metabolism enables Salmonella evasion of the NLRP3 inflammasome.
Volume: 211
Issue: 4
Pages: 653-68
Publication
First Author: Boaru SG
Year: 2015
Journal: Biochem Biophys Res Commun
Title: NLRP3 inflammasome expression is driven by NF-κB in cultured hepatocytes.
Volume: 458
Issue: 3
Pages: 700-6
Publication
First Author: Liu X
Year: 2017
Journal: Antioxid Redox Signal
Title: Nuclear Factor E2-Related Factor-2 Negatively Regulates NLRP3 Inflammasome Activity by Inhibiting Reactive Oxygen Species-Induced NLRP3 Priming.
Volume: 26
Issue: 1
Pages: 28-43
Publication  
First Author: Tengesdal IW
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion.
Volume: 118
Issue: 10
Publication
First Author: Costa A
Year: 2012
Journal: J Immunol
Title: Activation of the NLRP3 inflammasome by group B streptococci.
Volume: 188
Issue: 4
Pages: 1953-60
Publication
First Author: Nakamura Y
Year: 2012
Journal: Immunity
Title: Critical role for mast cells in interleukin-1β-driven skin inflammation associated with an activating mutation in the nlrp3 protein.
Volume: 37
Issue: 1
Pages: 85-95
Publication
First Author: Kailasan Vanaja S
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Bacterial RNA:DNA hybrids are activators of the NLRP3 inflammasome.
Volume: 111
Issue: 21
Pages: 7765-70
Publication  
First Author: Li X
Year: 2017
Journal: Nat Commun
Title: MARK4 regulates NLRP3 positioning and inflammasome activation through a microtubule-dependent mechanism.
Volume: 8
Pages: 15986
Publication
First Author: Zhu L
Year: 2014
Journal: FEBS Lett
Title: The transcription factor GFI1 negatively regulates NLRP3 inflammasome activation in macrophages.
Volume: 588
Issue: 23
Pages: 4513-9
Publication
First Author: Neudecker V
Year: 2017
Journal: J Exp Med
Title: Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome.
Volume: 214
Issue: 6
Pages: 1737-1752
Publication
First Author: Wang L
Year: 2023
Journal: Mol Cell
Title: Palmitoylation prevents sustained inflammation by limiting NLRP3 inflammasome activation through chaperone-mediated autophagy.
Volume: 83
Issue: 2
Pages: 281-297.e10
Publication  
First Author: Ma M
Year: 2021
Journal: Front Immunol
Title: Inhibition of the Inflammasome Activity of NLRP3 Attenuates HDM-Induced Allergic Asthma.
Volume: 12
Pages: 718779
Publication  
First Author: Liao J
Year: 2015
Journal: Nat Commun
Title: The NLRP3 inflammasome is critically involved in the development of bronchopulmonary dysplasia.
Volume: 6
Pages: 8977
Publication
First Author: Rajan JV
Year: 2011
Journal: J Virol
Title: The NLRP3 inflammasome detects encephalomyocarditis virus and vesicular stomatitis virus infection.
Volume: 85
Issue: 9
Pages: 4167-72
Publication
First Author: Marín-Aguilar F
Year: 2020
Journal: Aging Cell
Title: NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice.
Volume: 19
Issue: 1
Pages: e13050
Publication
First Author: Song-Zhao GX
Year: 2014
Journal: Mucosal Immunol
Title: Nlrp3 activation in the intestinal epithelium protects against a mucosal pathogen.
Volume: 7
Issue: 4
Pages: 763-774
Publication  
First Author: Basu S
Year: 2018
Journal: Microb Pathog
Title: NLRP3 inflammasome activation by mycobacterial ESAT-6 and dsRNA in intraocular tuberculosis.
Volume: 114
Pages: 219-224
Publication
First Author: Meng G
Year: 2010
Journal: Eur J Immunol
Title: New insights into the nature of autoinflammatory diseases from mice with Nlrp3 mutations.
Volume: 40
Issue: 3
Pages: 649-53
Publication
First Author: Conos SA
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner.
Volume: 114
Issue: 6
Pages: E961-E969
Publication
First Author: Misawa T
Year: 2013
Journal: Nat Immunol
Title: Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome.
Volume: 14
Issue: 5
Pages: 454-60
Publication
First Author: Humphries F
Year: 2018
Journal: Nat Commun
Title: The E3 ubiquitin ligase Pellino2 mediates priming of the NLRP3 inflammasome.
Volume: 9
Issue: 1
Pages: 1560
Publication  
First Author: Deng Q
Year: 2019
Journal: Cancer Lett
Title: NLRP3 inflammasomes in macrophages drive colorectal cancer metastasis to the liver.
Volume: 442
Pages: 21-30
Publication
First Author: Gelfand BD
Year: 2015
Journal: Cell Rep
Title: Iron Toxicity in the Retina Requires Alu RNA and the NLRP3 Inflammasome.
Volume: 11
Issue: 11
Pages: 1686-93
Publication
First Author: Stutz A
Year: 2017
Journal: J Exp Med
Title: NLRP3 inflammasome assembly is regulated by phosphorylation of the pyrin domain.
Volume: 214
Issue: 6
Pages: 1725-1736
Publication
First Author: Di A
Year: 2018
Journal: Immunity
Title: The TWIK2 Potassium Efflux Channel in Macrophages Mediates NLRP3 Inflammasome-Induced Inflammation.
Volume: 49
Issue: 1
Pages: 56-65.e4
Publication
First Author: Dong H
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Mitochondrial calcium uniporter promotes phagocytosis-dependent activation of the NLRP3 inflammasome.
Volume: 119
Issue: 26
Pages: e2123247119
Publication
First Author: Kaverina N
Year: 2023
Journal: Aging (Albany NY)
Title: Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span.
Volume: 15
Issue: 14
Pages: 6658-6689
Publication
First Author: Stancu IC
Year: 2022
Journal: Glia
Title: The NLRP3 inflammasome modulates tau pathology and neurodegeneration in a tauopathy model.
Volume: 70
Issue: 6
Pages: 1117-1132
Publication
First Author: Deora V
Year: 2020
Journal: Glia
Title: The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins.
Volume: 68
Issue: 2
Pages: 407-421
Publication
First Author: Beyer MMS
Year: 2020
Journal: J Neurosci
Title: Enduring Changes in Neuronal Function upon Systemic Inflammation Are NLRP3 Inflammasome Dependent.
Volume: 40
Issue: 28
Pages: 5480-5494
Publication
First Author: Bonar SL
Year: 2012
Journal: PLoS One
Title: Constitutively activated NLRP3 inflammasome causes inflammation and abnormal skeletal development in mice.
Volume: 7
Issue: 4
Pages: e35979
Publication
First Author: Allen IC
Year: 2012
Journal: J Immunol
Title: Analysis of NLRP3 in the development of allergic airway disease in mice.
Volume: 188
Issue: 6
Pages: 2884-93
Publication  
First Author: Du Q
Year: 2016
Journal: Biochem Pharmacol
Title: Dietary cholesterol promotes AOM-induced colorectal cancer through activating the NLRP3 inflammasome.
Volume: 105
Pages: 42-54
Publication
First Author: Jeon SA
Year: 2017
Journal: Int J Neuropsychopharmacol
Title: NLRP3 Inflammasome Contributes to Lipopolysaccharide-induced Depressive-Like Behaviors via Indoleamine 2,3-dioxygenase Induction.
Volume: 20
Issue: 11
Pages: 896-906
Publication
First Author: Fukui S
Year: 2022
Journal: Sci Rep
Title: NLRP3 inflammasome activation in neutrophils directs early inflammatory response in murine peritonitis.
Volume: 12
Issue: 1
Pages: 21313
Publication
First Author: Lin L
Year: 2019
Journal: PLoS Pathog
Title: An NLRP3 inflammasome-triggered cytokine storm contributes to Streptococcal toxic shock-like syndrome (STSLS).
Volume: 15
Issue: 6
Pages: e1007795
Publication
First Author: Chen Y
Year: 2015
Journal: Biochim Biophys Acta
Title: Endothelial Nlrp3 inflammasome activation associated with lysosomal destabilization during coronary arteritis.
Volume: 1853
Issue: 2
Pages: 396-408
Publication
First Author: Gonçalves AC
Year: 2017
Journal: Immunology
Title: The NLRP3 inflammasome contributes to host protection during Sporothrix schenckii infection.
Volume: 151
Issue: 2
Pages: 154-166
Publication
First Author: Fais RS
Year: 2019
Journal: Sci Rep
Title: The inflammasome NLRP3 plays a dual role on mouse corpora cavernosa relaxation.
Volume: 9
Issue: 1
Pages: 16224
Publication  
First Author: Cui M
Year: 2020
Journal: Int Immunopharmacol
Title: NLRP3 inflammasome is involved in nerve recovery after sciatic nerve injury.
Volume: 84
Pages: 106492
Publication
First Author: Schweneker K
Year: 2013
Journal: Immunobiology
Title: The mycobacterial cord factor adjuvant analogue trehalose-6,6'-dibehenate (TDB) activates the Nlrp3 inflammasome.
Volume: 218
Issue: 4
Pages: 664-73
Publication
First Author: Cho MH
Year: 2014
Journal: Autophagy
Title: Autophagy in microglia degrades extracellular β-amyloid fibrils and regulates the NLRP3 inflammasome.
Volume: 10
Issue: 10
Pages: 1761-75
Publication
First Author: Joly S
Year: 2009
Journal: J Immunol
Title: Cutting edge: Candida albicans hyphae formation triggers activation of the Nlrp3 inflammasome.
Volume: 183
Issue: 6
Pages: 3578-81
Publication  
First Author: Papafragkos I
Year: 2022
Journal: Front Immunol
Title: Ablation of NLRP3 inflammasome rewires MDSC function and promotes tumor regression.
Volume: 13
Pages: 889075
Publication
First Author: Hao H
Year: 2017
Journal: Cell Metab
Title: Farnesoid X Receptor Regulation of the NLRP3 Inflammasome Underlies Cholestasis-Associated Sepsis.
Volume: 25
Issue: 4
Pages: 856-867.e5
Publication
First Author: Inoue M
Year: 2016
Journal: Nat Neurosci
Title: An interferon-β-resistant and NLRP3 inflammasome-independent subtype of EAE with neuronal damage.
Volume: 19
Issue: 12
Pages: 1599-1609
Publication    
First Author: Green JP
Year: 2020
Journal: Elife
Title: LRRC8A is essential for hypotonicity-, but not for DAMP-induced NLRP3 inflammasome activation.
Volume: 9
Publication
First Author: Huang H
Year: 2018
Journal: Clin Exp Immunol
Title: Vitamin D receptor interacts with NLRP3 to restrict the allergic response.
Volume: 194
Issue: 1
Pages: 17-26
Publication
First Author: Hughes FM Jr
Year: 2019
Journal: Diabetes
Title: NLRP3 Promotes Diabetic Bladder Dysfunction and Changes in Symptom-Specific Bladder Innervation.
Volume: 68
Issue: 2
Pages: 430-440
Publication  
First Author: Karmakar M
Year: 2016
Journal: Nat Commun
Title: Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP.
Volume: 7
Pages: 10555
Publication
First Author: Jong WM
Year: 2013
Journal: Cardiovasc Res
Title: A role for NLRP3 inflammasome in acute myocardial ischaemia-reperfusion injury?
Volume: 99
Issue: 1
Pages: 226
Publication
First Author: Huang L
Year: 2019
Journal: Respir Res
Title: NLRP3 deletion inhibits inflammation-driven mouse lung tumorigenesis induced by benzo(a)pyrene and lipopolysaccharide.
Volume: 20
Issue: 1
Pages: 20
Publication
First Author: Wree A
Year: 2014
Journal: Hepatology
Title: NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice.
Volume: 59
Issue: 3
Pages: 898-910
Publication  
First Author: Gurung P
Year: 2015
Journal: Sci Rep
Title: Chronic TLR Stimulation Controls NLRP3 Inflammasome Activation through IL-10 Mediated Regulation of NLRP3 Expression and Caspase-8 Activation.
Volume: 5
Pages: 14488
Publication  
First Author: Bourne JH
Year: 2023
Journal: Front Immunol
Title: Megakaryocyte NLRP3 hyperactivation induces mild anemia and potentiates inflammatory response in mice.
Volume: 14
Pages: 1226196
Publication
First Author: Alippe Y
Year: 2021
Journal: FASEB J
Title: Actions of the NLRP3 and NLRC4 inflammasomes overlap in bone resorption.
Volume: 35
Issue: 9
Pages: e21837
Publication
First Author: Heneka MT
Year: 2013
Journal: Nature
Title: NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.
Volume: 493
Issue: 7434
Pages: 674-8
Publication
First Author: Wen Y
Year: 2016
Journal: Oncotarget
Title: NLRP3 inflammasome activation is involved in Ang II-induced kidney damage via mitochondrial dysfunction.
Volume: 7
Issue: 34
Pages: 54290-54302
Publication  
First Author: Ercan I
Year: 2023
Journal: Mol Cell Neurosci
Title: Bilirubin induces microglial NLRP3 inflammasome activation in vitro and in vivo.
Volume: 125
Pages: 103850
Publication
First Author: Franceschini A
Year: 2015
Journal: FASEB J
Title: The P2X7 receptor directly interacts with the NLRP3 inflammasome scaffold protein.
Volume: 29
Issue: 6
Pages: 2450-61
Publication  
First Author: Stackowicz J
Year: 2021
Journal: J Exp Med
Title: Neutrophil-specific gain-of-function mutations in Nlrp3 promote development of cryopyrin-associated periodic syndrome.
Volume: 218
Issue: 10
Publication  
First Author: Magupalli VG
Year: 2020
Journal: Science
Title: HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation.
Volume: 369
Issue: 6510
Publication
First Author: Laudisi F
Year: 2013
Journal: J Immunol
Title: Cutting edge: the NLRP3 inflammasome links complement-mediated inflammation and IL-1β release.
Volume: 191
Issue: 3
Pages: 1006-10
Publication
First Author: Youm YH
Year: 2013
Journal: Cell Metab
Title: Canonical Nlrp3 inflammasome links systemic low-grade inflammation to functional decline in aging.
Volume: 18
Issue: 4
Pages: 519-32
Publication
First Author: Panicker N
Year: 2022
Journal: Neuron
Title: Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson's disease.
Volume: 110
Issue: 15
Pages: 2422-2437.e9
Publication
First Author: Bauernfeind FG
Year: 2009
Journal: J Immunol
Title: Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.
Volume: 183
Issue: 2
Pages: 787-91
Publication  
First Author: Song H
Year: 2016
Journal: Nat Commun
Title: The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation by promoting proteasomal degradation of NLRP3.
Volume: 7
Pages: 13727
GO Term
Publication  
First Author: Ren GM
Year: 2021
Journal: Sci Immunol
Title: Pharmacological targeting of NLRP3 deubiquitination for treatment of NLRP3-associated inflammatory diseases.
Volume: 6
Issue: 58
Publication  
First Author: Rao Z
Year: 2019
Journal: Front Immunol
Title: Vitamin D Receptor Inhibits NLRP3 Activation by Impeding Its BRCC3-Mediated Deubiquitination.
Volume: 10
Pages: 2783
Publication
First Author: Kim JS
Year: 2023
Journal: Cell Mol Immunol
Title: Inhibition of CD82 improves colitis by increasing NLRP3 deubiquitination by BRCC3.
Volume: 20
Issue: 2
Pages: 189-200
Publication
First Author: Yao ST
Year: 2017
Journal: J Mol Neurosci
Title: NLRP3 is Required for Complement-Mediated Caspase-1 and IL-1beta Activation in ICH.
Volume: 61
Issue: 3
Pages: 385-395