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Search results 101 to 200 out of 8364 for Shh

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Type Details Score
Publication
15841179 | J:97323
First Author: Niedermaier M
Year: 2005
Journal: J Clin Invest
Title: An inversion involving the mouse Shh locus results in brachydactyly through dysregulation of Shh expression.
Volume: 115
Issue: 4
Pages: 900-9
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Publication
28263766 | J:241009
First Author: Himmelstein DS
Year: 2017
Journal: Dev Biol
Title: SHH E176/E177-Zn2+ conformation is required for signaling at endogenous sites.
Volume: 424
Issue: 2
Pages: 221-235
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Publication
24370450 | J:206883
First Author: Murashima A
Year: 2014
Journal: Dev Biol
Title: Midline-derived Shh regulates mesonephric tubule formation through the paraxial mesoderm.
Volume: 386
Issue: 1
Pages: 216-26
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Publication
21926481 | J:241750
First Author: Cui CY
Year: 2011
Journal: Cell Cycle
Title: Shh is required for Tabby hair follicle development.
Volume: 10
Issue: 19
Pages: 3379-86
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Publication
10500184 | J:57950
First Author: Tsukui T
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the shh and retinoic acid pathways in the control of Lefty-1.
Volume: 96
Issue: 20
Pages: 11376-81
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Publication
19298856 | J:149237
First Author: Perez-Balaguer A
Year: 2009
Journal: Mech Dev
Title: Shh dependent and independent maintenance of basal midbrain.
Volume: 126
Issue: 5-6
Pages: 301-13
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Publication
16336945 | J:105340
First Author: Tan M
Year: 2006
Journal: Brain Res
Title: Gli3 mutation rescues the generation, but not the differentiation, of oligodendrocytes in Shh mutants.
Volume: 1067
Issue: 1
Pages: 158-63
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Publication
16054035 | J:100687
First Author: Mill P
Year: 2005
Journal: Dev Cell
Title: Shh controls epithelial proliferation via independent pathways that converge on N-Myc.
Volume: 9
Issue: 2
Pages: 293-303
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Publication
12032320 | J:82883
First Author: Lettice LA
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Disruption of a long-range cis-acting regulator for Shh causes preaxial polydactyly.
Volume: 99
Issue: 11
Pages: 7548-53
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Publication
19855020 | J:154448
First Author: Bastida MF
Year: 2009
Journal: Development
Title: A BMP-Shh negative-feedback loop restricts Shh expression during limb development.
Volume: 136
Issue: 22
Pages: 3779-89
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Publication
11955708 | J:79931
First Author: Ohkubo Y
Year: 2002
Journal: Neuroscience
Title: Coordinate regulation and synergistic actions of BMP4, SHH and FGF8 in the rostral prosencephalon regulate morphogenesis of the telencephalic and optic vesicles.
Volume: 111
Issue: 1
Pages: 1-17
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Publication
37442233 | J:338900
First Author: Huang R
Year: 2023
Journal: J Biol Chem
Title: ISL1 regulates lung branching morphogenesis via Shh signaling pathway.
Volume: 299
Issue: 8
Pages: 105034
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Publication
10512189 | J:60109
First Author: Hardcastle Z
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: The Shh signalling pathway in early tooth development.
Volume: 45
Issue: 5
Pages: 567-78
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Publication
19122665 | J:146200
First Author: Joksimovic M
Year: 2009
Journal: Nat Neurosci
Title: Wnt antagonism of Shh facilitates midbrain floor plate neurogenesis.
Volume: 12
Issue: 2
Pages: 125-31
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Publication
11017169 | J:64758
First Author: Litingtung Y
Year: 2000
Journal: Nat Neurosci
Title: Specification of ventral neuron types is mediated by an antagonistic interaction between Shh and Gli3.
Volume: 3
Issue: 10
Pages: 979-85
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Publication
9858693 | J:51701
First Author: Motoyama J
Year: 1998
Journal: Mech Dev
Title: Overlapping and non-overlapping Ptch2 expression with Shh during mouse embryogenesis.
Volume: 78
Issue: 1-2
Pages: 81-4
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Publication
24968361 | J:214968
First Author: Cho G
Year: 2014
Journal: Dev Biol
Title: Arx together with FoxA2, regulates Shh floor plate expression.
Volume: 393
Issue: 1
Pages: 137-48
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Publication
16169547 | J:103457
First Author: Li C
Year: 2005
Journal: Dev Biol
Title: Wnt5a regulates Shh and Fgf10 signaling during lung development.
Volume: 287
Issue: 1
Pages: 86-97
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Publication
22038040 | J:314651
First Author: Lee JM
Year: 2011
Journal: Histochem Cell Biol
Title: Shh signaling is essential for rugae morphogenesis in mice.
Volume: 136
Issue: 6
Pages: 663-75
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GXD Expression
GXD Expression
   
Probe: MGI:1889613
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616517
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7380665
Age: embryonic day 10.5
Specimen Label: 1A Shh WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:1889613
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616515
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:7380665
Age: embryonic day 9.5
Specimen Label: 2 Shh WT
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:1889613
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1616515
Stage: TS15
Assay Id: MGI:7380665
Age: embryonic day 9.5
Specimen Label: 2 Shh bromi
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:1889613
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1616515
Stage: TS15
Assay Id: MGI:7380665
Age: embryonic day 9.5
Note: Expression pattern similar to bromi single mutant.
Specimen Label: 2 Shh bromi,Ptch1
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:1889613
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616517
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7380665
Age: embryonic day 10.5
Specimen Label: S2C Shh WT
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:1889613
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616517
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7380665
Age: embryonic day 10.5
Specimen Label: S4B Shh WT
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
   
Probe: MGI:7606836
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616515
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:7606872
Age: embryonic day 9.5
Specimen Label: 4F +/+ Shh
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7606836
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1616515
Stage: TS15
Assay Id: MGI:7606872
Age: embryonic day 9.5
Specimen Label: 4F -/- Shh
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:1889613
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616415
Pattern: Widespread
Stage: TS15
Assay Id: MGI:7380665
Age: embryonic day 9.5
Note: Broadly expressed throughout open neural tube.
Specimen Label: 2 Shh Ptch1
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:1889613
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1616417
Stage: TS17
Assay Id: MGI:7380665
Age: embryonic day 10.5
Specimen Label: 1A Shh bromi
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:1889613
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1616417
Stage: TS17
Assay Id: MGI:7380665
Age: embryonic day 10.5
Specimen Label: S2C Shh bromi
Detected: false
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:1889613
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7380665
Age: embryonic day 10.5
Note: Expression domain shifted compared to wild type.
Specimen Label: S2C Shh Rab23opb2
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:1889613
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1616417
Stage: TS17
Assay Id: MGI:7380665
Age: embryonic day 10.5
Note: Authors report same dorsalized phenotype as in bromi single mutants.
Specimen Label: S2C Shh bromi,Rab23opb2
Detected: false
Specimen Num: 10
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GXD Expression
GXD Expression
   
Probe: MGI:1889613
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1616417
Stage: TS17
Assay Id: MGI:7380665
Age: embryonic day 10.5
Note: Expression identical to that of bromi mutants.
Specimen Label: S4B Shh RRF/RRF
Detected: false
Specimen Num: 12
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GXD Expression
GXD Expression
   
Probe: MGI:1889613
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619117
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7380665
Age: embryonic day 10.5
Specimen Label: 1A Shh WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:1889613
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619117
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7380665
Age: embryonic day 10.5
Specimen Label: 1A Shh bromi
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:1889613
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619117
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7380665
Age: embryonic day 10.5
Specimen Label: S2C Shh WT
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:1889613
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619117
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7380665
Age: embryonic day 10.5
Specimen Label: S2C Shh bromi
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:1889613
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619117
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7380665
Age: embryonic day 10.5
Specimen Label: S4B Shh WT
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
   
Probe: MGI:1889613
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619117
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7380665
Age: embryonic day 10.5
Specimen Label: S4B Shh RRF/RRF
Detected: true
Specimen Num: 12
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Publication
25799573 | J:229187
First Author: Kurosaka H
Year: 2015
Journal: PLoS One
Title: Cranial nerve development requires co-ordinated Shh and canonical Wnt signaling.
Volume: 10
Issue: 3
Pages: e0120821
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Publication
23201023 | J:193109
First Author: Hayes L
Year: 2013
Journal: Dev Biol
Title: Duration of Shh signaling contributes to mDA neuron diversity.
Volume: 374
Issue: 1
Pages: 115-26
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Publication
15065125 | J:109287
First Author: Balmer CW
Year: 2004
Journal: J Comp Neurol
Title: Loss of Gli3 and Shh function disrupts olfactory axon trajectories.
Volume: 472
Issue: 3
Pages: 292-307
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Publication
12198547 | J:78941
First Author: Litingtung Y
Year: 2002
Journal: Nature
Title: Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity.
Volume: 418
Issue: 6901
Pages: 979-83
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Publication
19141668 | J:144194
First Author: Suzuki K
Year: 2009
Journal: Development
Title: Embryonic hair follicle fate change by augmented beta-catenin through Shh and Bmp signaling.
Volume: 136
Issue: 3
Pages: 367-72
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Publication
17504941 | J:121553
First Author: Allen BL
Year: 2007
Journal: Genes Dev
Title: The Hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse development.
Volume: 21
Issue: 10
Pages: 1244-57
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Publication
16766714 | J:174118
 
First Author: Fuccillo M
Year: 2006
Journal: Cereb Cortex
Title: Removal of Pax6 partially rescues the loss of ventral structures in Shh null mice.
Volume: 16 Suppl 1
Pages: i96-102
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Publication
15629701 | J:95822
First Author: Cai J
Year: 2005
Journal: Neuron
Title: Generation of oligodendrocyte precursor cells from mouse dorsal spinal cord independent of Nkx6 regulation and Shh signaling.
Volume: 45
Issue: 1
Pages: 41-53
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Publication
17284610 | J:119729
First Author: Iwatsuki K
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Wnt signaling interacts with Shh to regulate taste papilla development.
Volume: 104
Issue: 7
Pages: 2253-8
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Publication
24892825 | J:218511
First Author: Winkler T
Year: 2014
Journal: PLoS One
Title: Wnt signaling activates Shh signaling in early postnatal intervertebral discs, and re-activates Shh signaling in old discs in the mouse.
Volume: 9
Issue: 6
Pages: e98444
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Publication
11023872 | J:64678
First Author: Epstein DJ
Year: 2000
Journal: Development
Title: Members of the bHLH-PAS family regulate Shh transcription in forebrain regions of the mouse CNS.
Volume: 127
Issue: 21
Pages: 4701-9
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Publication
28891097 | J:252110
First Author: Iulianella A
Year: 2018
Journal: Dev Dyn
Title: Ventral neural patterning in the absence of a Shh activity gradient from the floorplate.
Volume: 247
Issue: 1
Pages: 170-184
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Publication
19433083 | J:150755
First Author: Oh S
Year: 2009
Journal: Dev Biol
Title: Shh and Gli3 activities are required for timely generation of motor neuron progenitors.
Volume: 331
Issue: 2
Pages: 261-9
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Publication
17553904 | J:122745
First Author: Vierkotten J
Year: 2007
Journal: Development
Title: Ftm is a novel basal body protein of cilia involved in Shh signalling.
Volume: 134
Issue: 14
Pages: 2569-77
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Publication
16611729 | J:109101
First Author: Li Y
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Cholesterol modification restricts the spread of Shh gradient in the limb bud.
Volume: 103
Issue: 17
Pages: 6548-53
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Publication
21976698 | J:206912
First Author: Larkins CE
Year: 2011
Journal: Mol Biol Cell
Title: Arl13b regulates ciliogenesis and the dynamic localization of Shh signaling proteins.
Volume: 22
Issue: 23
Pages: 4694-703
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Publication
19014928 | J:143534
First Author: Kim JY
Year: 2009
Journal: Dev Biol
Title: Shh and ROCK1 modulate the dynamic epithelial morphogenesis in circumvallate papilla development.
Volume: 325
Issue: 1
Pages: 273-80
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Publication
12361967 | J:79392
First Author: Bai CB
Year: 2002
Journal: Development
Title: Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway.
Volume: 129
Issue: 20
Pages: 4753-61
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Publication
21925158 | J:178496
First Author: Rash BG
Year: 2011
Journal: Dev Biol
Title: Shh and Gli3 regulate formation of the telencephalic-diencephalic junction and suppress an isthmus-like signaling source in the forebrain.
Volume: 359
Issue: 2
Pages: 242-50
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Publication
27402708 | J:236316
First Author: Williamson I
Year: 2016
Journal: Development
Title: Shh and ZRS enhancer colocalisation is specific to the zone of polarising activity.
Volume: 143
Issue: 16
Pages: 2994-3001
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Publication
34463328 | J:310346
 
First Author: Mecklenburg N
Year: 2021
Journal: Development
Title: Identification of disease-relevant modulators of the SHH pathway in the developing brain.
Volume: 148
Issue: 17
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Publication
12835403 | J:84605
First Author: Jeong Y
Year: 2003
Journal: Development
Title: Distinct regulators of Shh transcription in the floor plate and notochord indicate separate origins for these tissues in the mouse node.
Volume: 130
Issue: 16
Pages: 3891-902
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Publication
35132078 | J:321068
First Author: Maimets M
Year: 2022
Journal: Nat Commun
Title: Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling.
Volume: 13
Issue: 1
Pages: 715
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Publication
23624372 | J:198688
First Author: Sanders TA
Year: 2013
Journal: Nature
Title: Specialized filopodia direct long-range transport of SHH during vertebrate tissue patterning.
Volume: 497
Issue: 7451
Pages: 628-32
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Publication
15315763 | J:92504
First Author: Harfe BD
Year: 2004
Journal: Cell
Title: Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities.
Volume: 118
Issue: 4
Pages: 517-28
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Publication
18836447 | J:186828
First Author: Jeong Y
Year: 2008
Journal: Nat Genet
Title: Regulation of a remote Shh forebrain enhancer by the Six3 homeoprotein.
Volume: 40
Issue: 11
Pages: 1348-53
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Publication
21509901 | J:170964
First Author: Zhu J
Year: 2011
Journal: Dev Dyn
Title: Analysis of mutants with altered shh activity and posterior digit loss supports a biphasic model for shh function as a morphogen and mitogen.
Volume: 240
Issue: 5
Pages: 1303-10
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Publication
24990743 | J:213641
First Author: Lopez-Rios J
Year: 2014
Journal: Nature
Title: Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs.
Volume: 511
Issue: 7507
Pages: 46-51
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Publication
17409116 | J:121263
First Author: Vaillant C
Year: 2007
Journal: Development
Title: Protease nexin 1 and its receptor LRP modulate SHH signalling during cerebellar development.
Volume: 134
Issue: 9
Pages: 1745-54
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Publication
15858818 | J:98357
First Author: Bell SM
Year: 2005
Journal: Dev Dyn
Title: Shh signaling in limb bud ectoderm: potential role in teratogen-induced postaxial ectrodactyly.
Volume: 233
Issue: 2
Pages: 313-25
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Publication
25826604 | J:222417
First Author: Sloan TF
Year: 2015
Journal: PLoS Biol
Title: Integration of shallow gradients of Shh and Netrin-1 guides commissural axons.
Volume: 13
Issue: 3
Pages: e1002119
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Publication
19887680 | J:186055
First Author: Ashique AM
Year: 2009
Journal: Sci Signal
Title: The Rfx4 transcription factor modulates Shh signaling by regional control of ciliogenesis.
Volume: 2
Issue: 95
Pages: ra70
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Publication
19906863 | J:158288
First Author: Lin C
Year: 2009
Journal: Development
Title: Temporal and spatial dissection of Shh signaling in genital tubercle development.
Volume: 136
Issue: 23
Pages: 3959-67
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Publication
22064698 | J:316104
First Author: Song L
Year: 2012
Journal: Cell Res
Title: Shh signaling guides spatial pathfinding of raphespinal tract axons by multidirectional repulsion.
Volume: 22
Issue: 4
Pages: 697-716
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Publication
9230312 | J:41620
First Author: Ericson J
Year: 1997
Journal: Cell
Title: Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling.
Volume: 90
Issue: 1
Pages: 169-80
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Publication
19211681 | J:146634
First Author: Ohazama A
Year: 2009
Journal: Development
Title: Primary cilia regulate Shh activity in the control of molar tooth number.
Volume: 136
Issue: 6
Pages: 897-903
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Publication
9655803 | J:49252
First Author: Hardcastle Z
Year: 1998
Journal: Development
Title: The Shh signalling pathway in tooth development: defects in Gli2 and Gli3 mutants.
Volume: 125
Issue: 15
Pages: 2803-11
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•
•
•
•
Publication
23315474 | J:196977
First Author: Nakatomi M
Year: 2013
Journal: J Dent Res
Title: Evc regulates a symmetrical response to Shh signaling in molar development.
Volume: 92
Issue: 3
Pages: 222-8
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•
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•
Publication
23153497 | J:191081
First Author: Oosterveen T
Year: 2012
Journal: Dev Cell
Title: Mechanistic differences in the transcriptional interpretation of local and long-range Shh morphogen signaling.
Volume: 23
Issue: 5
Pages: 1006-19
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Publication
19494112 | J:153183
First Author: Leow CC
Year: 2009
Journal: J Biol Chem
Title: Prostate-specific Klf6 inactivation impairs anterior prostate branching morphogenesis through increased activation of the Shh pathway.
Volume: 284
Issue: 31
Pages: 21057-65
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Publication
11044396 | J:207822
First Author: Sanz-Ezquerro JJ
Year: 2000
Journal: Development
Title: Autoregulation of Shh expression and Shh induction of cell death suggest a mechanism for modulating polarising activity during chick limb development.
Volume: 127
Issue: 22
Pages: 4811-23
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Publication
25249463 | J:217500
First Author: Cui CY
Year: 2014
Journal: Development
Title: Involvement of Wnt, Eda and Shh at defined stages of sweat gland development.
Volume: 141
Issue: 19
Pages: 3752-60
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Publication
30853403 | J:275465
First Author: Mazzonetto PC
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Mutation in NADPH oxidase 3 (NOX3) impairs SHH signaling and increases cerebellar neural stem/progenitor cell proliferation.
Volume: 1865
Issue: 6
Pages: 1502-1515
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GXD Expression
GXD Expression
   
Probe: MGI:1327804
Assay Type: RNA in situ
Annotation Date: 2020-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619115
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:6391086
Age: embryonic day 9.5
Specimen Label: E9.5 Shh WT not shown
Detected: true
Specimen Num: 1
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•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:1327804
Assay Type: RNA in situ
Annotation Date: 2020-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619117
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6391086
Age: embryonic day 10.5
Specimen Label: E10.5 Shh WT not shown
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1327804
Assay Type: RNA in situ
Annotation Date: 2020-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619117
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6391086
Age: embryonic day 10.5
Note: Expression remained normal in notochord.
Specimen Label: E10.5 Shh Pbx1-/-;Pbx2+/- not shown
Detected: true
Specimen Num: 4
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1327804
Assay Type: RNA in situ
Annotation Date: 2020-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619115
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:6391086
Age: embryonic day 9.5
Note: Expression remained normal in notochord.
Specimen Label: E9.5 Shh Pbx1-/-;Pbx2+/- not shown
Detected: true
Specimen Num: 2
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7576825
Assay Type: RNA in situ
Annotation Date: 2024-01-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640618
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:7576853
Age: embryonic day 10.75
Image: S6 Id1 E10.75 Shh delta/delta
Specimen Label: S6 Id1 E10.75 Shh delta/delta
Detected: true
Specimen Num: 6
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7576848
Assay Type: RNA in situ
Annotation Date: 2024-01-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640618
Pattern: Regionally restricted
Stage: TS18
Assay Id: MGI:7576876
Age: embryonic day 10.75
Image: S6 Smoc1 E10.75 Shh delta/delta
Note: Authors report differential expression compared to control.
Specimen Label: S6 Smoc1 E10.75 Shh delta/delta
Detected: true
Specimen Num: 6
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Publication
35974013 | J:332336
First Author: Schmidt S
Year: 2022
Journal: Nat Commun
Title: Primary cilia and SHH signaling impairments in human and mouse models of Parkinson's disease.
Volume: 13
Issue: 1
Pages: 4819
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Publication
24415953 | J:205405
First Author: Kozhemyakina E
Year: 2014
Journal: PLoS Genet
Title: GATA6 is a crucial regulator of Shh in the limb bud.
Volume: 10
Issue: 1
Pages: e1004072
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Publication
22383895 | J:183402
First Author: Taniguchi K
Year: 2012
Journal: PLoS Genet
Title: Loss of Tgif function causes holoprosencephaly by disrupting the SHH signaling pathway.
Volume: 8
Issue: 2
Pages: e1002524
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•
Publication
12154128 | J:78248
First Author: Zeng L
Year: 2002
Journal: Genes Dev
Title: Shh establishes an Nkx3.2/Sox9 autoregulatory loop that is maintained by BMP signals to induce somitic chondrogenesis.
Volume: 16
Issue: 15
Pages: 1990-2005
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Publication
21455944 | J:173580
First Author: Hovorakova M
Year: 2011
Journal: J Exp Zool B Mol Dev Evol
Title: Shh expression in a rudimentary tooth offers new insights into development of the mouse incisor.
Volume: 316
Issue: 5
Pages: 347-58
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•
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Publication
24157522 | J:207862
 
First Author: Tsukiji N
Year: 2014
Journal: Mech Dev
Title: A novel regulatory element for Shh expression in the lung and gut of mouse embryos.
Volume: 131
Pages: 127-36
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•
•
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Publication
23913503 | J:213693
First Author: Hovorakova M
Year: 2013
Journal: J Exp Zool B Mol Dev Evol
Title: Sequential Shh expression in the development of the mouse upper functional incisor.
Volume: 320
Issue: 7
Pages: 455-64
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Publication
16951180 | J:112411
First Author: Hatton BA
Year: 2006
Journal: Cancer Res
Title: N-myc is an essential downstream effector of Shh signaling during both normal and neoplastic cerebellar growth.
Volume: 66
Issue: 17
Pages: 8655-61
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Publication
33863876 | J:306058
First Author: Ushiki A
Year: 2021
Journal: Nat Commun
Title: Deletion of CTCF sites in the SHH locus alters enhancer-promoter interactions and leads to acheiropodia.
Volume: 12
Issue: 1
Pages: 2282
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Publication
19097946 | J:145170
First Author: Amano T
Year: 2009
Journal: Dev Cell
Title: Chromosomal dynamics at the Shh locus: limb bud-specific differential regulation of competence and active transcription.
Volume: 16
Issue: 1
Pages: 47-57
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•
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Publication
24993944 | J:213854
First Author: Castillo D
Year: 2014
Journal: Development
Title: Induction of ectopic taste buds by SHH reveals the competency and plasticity of adult lingual epithelium.
Volume: 141
Issue: 15
Pages: 2993-3002
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Publication
27845689 | J:238726
First Author: Miyado M
Year: 2017
Journal: Reproduction
Title: Expression patterns of Fgf8 and Shh in the developing external genitalia of Suncus murinus.
Volume: 153
Issue: 2
Pages: 187-195
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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