Type |
Details |
Score |
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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•
•
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•
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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Allele |
Name: |
motor neuron and pancreas homeobox 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Inducible, Recombinase |
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•
•
•
•
•
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Allele |
Name: |
motor neuron and pancreas homeobox 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Recombinase |
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•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
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•
•
•
•
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Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
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•
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Allele |
Name: |
transgene insertion 1, Samuel L Pfaff |
Allele Type: |
Transgenic |
Attribute String: |
Reporter |
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•
•
•
•
•
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Publication |
First Author: |
Lee SK |
Year: |
2004 |
Journal: |
Development |
Title: |
Analysis of embryonic motoneuron gene regulation: derepression of general activators function in concert with enhancer factors. |
Volume: |
131 |
Issue: |
14 |
Pages: |
3295-306 |
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•
•
•
•
•
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Allele |
Name: |
transgene insertion 1, Samuel L Pfaff |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
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•
•
•
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Allele |
Name: |
transgene insertion, Thomas M Jessell |
Allele Type: |
Transgenic |
Attribute String: |
Reporter |
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•
•
•
•
•
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Allele |
Name: |
transgene insertion 1, Joshua R Sanes |
Allele Type: |
Transgenic |
Attribute String: |
Recombinase |
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•
•
•
•
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Allele |
Name: |
insulin related protein 2 (islet 2); targeted mutation 3.1, Samuel L Pfaff |
Allele Type: |
Targeted |
Attribute String: |
Inserted expressed sequence |
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•
•
•
•
•
|
Genotype |
Symbol: |
Tg(Mnx1-GFP)1Slp/? |
Background: |
involves: BALB/cJ * C57BL/6J |
Zygosity: |
ot |
Has Mutant Allele: |
true |
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•
•
•
•
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Protein Domain |
Type: |
Family |
Description: |
This entry represents a group of homeobox proteins, including Motor neuron and pancreas homeobox protein 1 (MNX1) from mammals and Ceh-12 from C. elegans. Mutations in the MNX1 gene cause Currarino syndrome (CURRAS), a triad composed of partial sacral agenesis with intact first sacral vertebra ("sickle-shaped sacrum"), presacral mass, and anorectal malformations []. |
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Allele |
Name: |
transgene insertion GX229, GENSAT Project at Rockefeller University |
Allele Type: |
Transgenic |
Attribute String: |
Reporter |
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•
•
•
•
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Strain |
Attribute String: |
mutant stock, targeted mutation |
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Publication |
First Author: |
Hinckley CA |
Year: |
2005 |
Journal: |
J Neurophysiol |
Title: |
Locomotor-like rhythms in a genetically distinct cluster of interneurons in the mammalian spinal cord. |
Volume: |
93 |
Issue: |
3 |
Pages: |
1439-49 |
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•
•
•
•
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Genotype |
Symbol: |
Isl2/Isl2<+> |
Background: |
Not Specified |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Arhgap35/Arhgap35 Tg(Mnx1-GFP)1Slp/? |
Background: |
involves: BALB/cJ * C57BL/6J * DBA/2J |
Zygosity: |
cx |
Has Mutant Allele: |
true |
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•
•
•
•
•
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Publication |
First Author: |
Mavlyutov TA |
Year: |
2010 |
Journal: |
Neuroscience |
Title: |
The sigma-1 receptor is enriched in postsynaptic sites of C-terminals in mouse motoneurons. An anatomical and behavioral study. |
Volume: |
167 |
Issue: |
2 |
Pages: |
247-55 |
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•
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Strain |
Attribute String: |
mutant stock, transgenic |
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Allele |
Name: |
transgene insertion 1, David C Chan |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence, Reporter |
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•
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•
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Genotype |
Symbol: |
Fgfr2/Fgfr2 Tg(Mnx1-cre)1Jrs/? |
Background: |
involves: 129X1/SvJ * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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•
•
•
•
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Genotype |
Symbol: |
Isl2/Isl2<+> Tg(Mnx1-GFP)1Slp/? |
Background: |
Not Specified |
Zygosity: |
cx |
Has Mutant Allele: |
true |
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•
•
•
•
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Genotype |
Symbol: |
Mycbp2/Mycbp2 Tg(Mnx1-GFP)1Slp/? |
Background: |
involves: C3H * C57BL/6 * DBA/2J |
Zygosity: |
cx |
Has Mutant Allele: |
true |
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•
•
•
•
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Genotype |
Symbol: |
Map3k12/Map3k12 Tg(Mnx1-GFP)1Slp/? |
Background: |
Not Specified |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
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•
•
•
•
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Allele |
Name: |
transgene insertion, Robert M Brownstone |
Allele Type: |
Transgenic |
Attribute String: |
Inducible, Recombinase |
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•
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•
•
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Publication |
First Author: |
Sharma K |
Year: |
2000 |
Journal: |
Nature |
Title: |
Genetic and epigenetic mechanisms contribute to motor neuron pathfinding. |
Volume: |
406 |
Issue: |
6795 |
Pages: |
515-9 |
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•
•
•
•
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Allele |
Name: |
transgene insertion 4, Robert M Brownstone |
Allele Type: |
Transgenic |
Attribute String: |
Inducible, Recombinase |
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Publication |
First Author: |
Detmer SA |
Year: |
2008 |
Journal: |
Hum Mol Genet |
Title: |
Hindlimb gait defects due to motor axon loss and reduced distal muscles in a transgenic mouse model of Charcot-Marie-Tooth type 2A. |
Volume: |
17 |
Issue: |
3 |
Pages: |
367-75 |
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•
•
•
•
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Allele |
Name: |
transgene insertion 8, Robert M Brownstone |
Allele Type: |
Transgenic |
Attribute String: |
Inducible, Recombinase |
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•
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•
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Genotype |
Symbol: |
Fgfr2/Fgfr2 Lamb2/Lamb2 Tg(Mnx1-cre)1Jrs/? |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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•
•
•
•
•
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Genotype |
Symbol: |
Tg(Mnx1-Mfn2*T105M,-EGFP)1Dcc/? |
Background: |
Not Specified |
Zygosity: |
ot |
Has Mutant Allele: |
true |
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•
•
•
•
•
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Genotype |
Symbol: |
Tg(Mnx1-Mfn2*T105M,-EGFP)1Dcc/Tg(Mnx1-Mfn2*T105M,-EGFP)1Dcc |
Background: |
Not Specified |
Zygosity: |
hm |
Has Mutant Allele: |
true |
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•
•
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HT Experiment |
|
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
ArrayExpress |
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Strain |
Attribute String: |
congenic |
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•
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Genotype |
Symbol: |
Fgfr1/Fgfr1 Tg(Mnx1-GFP)1Slp/? Tg(Nes-cre)1Kln/? |
Background: |
Not Specified |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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•
•
•
•
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Genotype |
Symbol: |
Robo3/Robo3 Tg(Mnx1-EGFP)#Tmj/? |
Background: |
involves: C57BL/6 * DBA |
Zygosity: |
cx |
Has Mutant Allele: |
true |
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•
•
•
•
•
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Publication |
First Author: |
Lee H |
Year: |
2021 |
Journal: |
Nat Neurosci |
Title: |
Multi-omic analysis of selectively vulnerable motor neuron subtypes implicates altered lipid metabolism in ALS. |
Volume: |
24 |
Issue: |
12 |
Pages: |
1673-1685 |
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•
•
•
•
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Genotype |
Symbol: |
Egr2/Egr2<+> Robo3/Robo3 Tg(Mnx1-EGFP)#Tmj/? |
Background: |
involves: 129S2/SvPas * C57BL/6 * DBA |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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•
•
•
•
•
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Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Mnx1-cre/ERT2)8Rbro/? |
Background: |
involves: 129X1/SvJ * C57BL/6 * CBA |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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•
•
•
•
•
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Publication |
First Author: |
Chopek JW |
Year: |
2018 |
Journal: |
Cell Rep |
Title: |
Sub-populations of Spinal V3 Interneurons Form Focal Modules of Layered Pre-motor Microcircuits. |
Volume: |
25 |
Issue: |
1 |
Pages: |
146-156.e3 |
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•
•
•
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Publication |
First Author: |
Sternfeld MJ |
Year: |
2017 |
Journal: |
Elife |
Title: |
Speed and segmentation control mechanisms characterized in rhythmically-active circuits created from spinal neurons produced from genetically-tagged embryonic stem cells. |
Volume: |
6 |
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•
•
•
•
•
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Publication |
First Author: |
Wang L |
Year: |
2014 |
Journal: |
Development |
Title: |
A conserved axon type hierarchy governing peripheral nerve assembly. |
Volume: |
141 |
Issue: |
9 |
Pages: |
1875-83 |
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•
•
•
•
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Publication |
First Author: |
Shin JE |
Year: |
2012 |
Journal: |
Neuron |
Title: |
Dual leucine zipper kinase is required for retrograde injury signaling and axonal regeneration. |
Volume: |
74 |
Issue: |
6 |
Pages: |
1015-22 |
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•
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•
•
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Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Mnx1-cre/ERT2)8Rbro/? |
Background: |
involves: 129S6/SvEvTac * C57BL/6 * CBA |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Mnx1-cre/ERT2)8Rbro/? |
Background: |
involves: 129S6/SvEvTac * C57BL/6 * CBA |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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•
•
•
•
•
|
Publication |
First Author: |
He W |
Year: |
2015 |
Journal: |
Nature |
Title: |
CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase. |
Volume: |
526 |
Issue: |
7575 |
Pages: |
710-4 |
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•
•
•
•
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Publication |
First Author: |
Lewcock JW |
Year: |
2007 |
Journal: |
Neuron |
Title: |
The ubiquitin ligase Phr1 regulates axon outgrowth through modulation of microtubule dynamics. |
Volume: |
56 |
Issue: |
4 |
Pages: |
604-20 |
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•
•
•
•
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Publication |
First Author: |
Schwander M |
Year: |
2004 |
Journal: |
J Neurosci |
Title: |
Beta1 integrins in muscle, but not in motor neurons, are required for skeletal muscle innervation. |
Volume: |
24 |
Issue: |
37 |
Pages: |
8181-91 |
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•
•
•
•
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Publication |
First Author: |
Fox MA |
Year: |
2007 |
Journal: |
Cell |
Title: |
Distinct target-derived signals organize formation, maturation, and maintenance of motor nerve terminals. |
Volume: |
129 |
Issue: |
1 |
Pages: |
179-93 |
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•
•
•
•
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Publication |
First Author: |
Shirasaki R |
Year: |
2006 |
Journal: |
Neuron |
Title: |
FGF as a target-derived chemoattractant for developing motor axons genetically programmed by the LIM code. |
Volume: |
50 |
Issue: |
6 |
Pages: |
841-53 |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
404
|
Fragment?: |
false |
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•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
404
|
Fragment?: |
false |
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•
•
•
•
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Publication |
First Author: |
Bonanomi D |
Year: |
2019 |
Journal: |
Neuron |
Title: |
p190RhoGAP Filters Competing Signals to Resolve Axon Guidance Conflicts. |
Volume: |
102 |
Issue: |
3 |
Pages: |
602-620.e9 |
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•
•
•
•
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Publication |
First Author: |
Wang L |
Year: |
2011 |
Journal: |
Neuron |
Title: |
Anatomical coupling of sensory and motor nerve trajectory via axon tracking. |
Volume: |
71 |
Issue: |
2 |
Pages: |
263-77 |
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•
•
•
•
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Publication |
First Author: |
Jain V |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
Gain control by sparse, ultra-slow glycinergic synapses. |
Volume: |
38 |
Issue: |
8 |
Pages: |
110410 |
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•
•
•
•
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Publication |
First Author: |
Bonanomi D |
Year: |
2012 |
Journal: |
Cell |
Title: |
Ret is a multifunctional coreceptor that integrates diffusible- and contact-axon guidance signals. |
Volume: |
148 |
Issue: |
3 |
Pages: |
568-82 |
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•
•
•
•
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Publication |
First Author: |
Arulkandarajah KH |
Year: |
2021 |
Journal: |
Curr Biol |
Title: |
Neuroepithelial progenitors generate and propagate non-neuronal action potentials across the spinal cord. |
Volume: |
31 |
Issue: |
20 |
Pages: |
4584-4595.e4 |
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•
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Publication |
First Author: |
Niu X |
Year: |
2020 |
Journal: |
J Neurosci |
Title: |
Mapping of Extrinsic Innervation of the Gastrointestinal Tract in the Mouse Embryo. |
Volume: |
40 |
Issue: |
35 |
Pages: |
6691-6708 |
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•
•
•
•
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Publication |
First Author: |
The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY) |
Year: |
2005 |
Journal: |
Database Download |
Title: |
MGI download of GENSAT transgene data |
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