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Search results 101 to 200 out of 395 for Cd72

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Type Details Score
Gene
108705002 | LOC108705002
Type: gene
Organism: frog, African clawed
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Gene
108719144 | LOC108719144
Type: gene
Organism: frog, African clawed
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Allele
Cd72<em1Smoc> | MGI:7288855
Name: CD72 antigen; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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UniProt Feature
UniProt Feature
Begin: 1
Description: B-cell differentiation antigen CD72
Type: chain
End: 354
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Protein
Q8CIX9
Organism: Mus musculus/domesticus
Length: 286  
Fragment?: true
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Protein
Q99L55
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: false
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Publication
9794407 | J:50442
First Author: Ying H
Year: 1998
Journal: J Immunol
Title: Regulation of mouse CD72 gene expression during B lymphocyte development.
Volume: 161
Issue: 9
Pages: 4760-7
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Publication
9590210 | -
First Author: Adachi T
Year: 1998
Journal: J Immunol
Title: The B cell surface protein CD72 recruits the tyrosine phosphatase SHP-1 upon tyrosine phosphorylation.
Volume: 160
Issue: 10
Pages: 4662-5
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Protein
A2AIN5
Organism: Mus musculus/domesticus
Length: 347  
Fragment?: false
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Protein
P21855
Organism: Mus musculus/domesticus
Length: 354  
Fragment?: false
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Protein
Q3UB58
Organism: Mus musculus/domesticus
Length: 300  
Fragment?: false
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Protein
Q3UNJ0
Organism: Mus musculus/domesticus
Length: 337  
Fragment?: false
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Protein
Q3UZ35
Organism: Mus musculus/domesticus
Length: 361  
Fragment?: false
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Publication
9498769 | J:45923
First Author: Ying H
Year: 1998
Journal: J Immunol
Title: PU.1/Spi-1 is essential for the B cell-specific activity of the mouse CD72 promoter.
Volume: 160
Issue: 5
Pages: 2287-96
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Allele
Cd72<a> | MGI:5563335
   
Name: CD72 antigen; a haplotype
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Strain
MGI:3656258 | B6.Cg-Cd72<a>/Rbrc
Attribute String: congenic, mutant strain
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Allele
Cd72<c> | MGI:5563235
   
Name: CD72 antigen; c haplotype
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Allele
Cd72<b> | MGI:5563237
   
Name: CD72 antigen; b haplotype
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Allele
Cd72<+> | MGI:2430273
   
Name: CD72 antigen; wild type
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Genotype
Genotype
Symbol: Cd72/Cd72
Background: involves: C57BL/6 * MRL
Zygosity: hm
Has Mutant Allele: true
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Allele
Cd72<em1Cya> | MGI:7582867
Name: CD72 antigen; endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Cd72<tm1Tsub> | MGI:5563226
Name: CD72 antigen; targeted mutation 1, Takeshi Tsubata
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
- | J:173977
     
First Author: Neuman de Vegvar HE
Year: 2011
Journal: MGI Direct Data Submission
Title: A new transgenic mouse expressing Cd72 from DBA/2 mice under the control of the immuglobulin light chain promoter
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Publication
11999169 | -
First Author: Wu HJ
Year: 2002
Journal: Immunol Res
Title: Positive and negative roles of CD72 in B cell function.
Volume: 25
Issue: 2
Pages: 155-66
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Strain
MGI:7590962 | C57BL/6J-Cd72<em1Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Cd72<tm1Jrp> | MGI:2180786
Name: CD72 antigen; targeted mutation 1, Jane R Parnes
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Cd72<em35Gpt> | MGI:7296616
Name: CD72 antigen; endonuclease-mediated mutation 35, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Cd72<tm1a(EUCOMM)Hmgu> | MGI:5294193
Name: CD72 antigen; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Cd72<tm1e(EUCOMM)Hmgu> | MGI:5294087
Name: CD72 antigen; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Genotype
Genotype
Symbol: Cd72/Cd72
Background: involves: C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:4429534 | B6.129P2-Cd72<tm1Jrp>/Mmmh
Attribute String: mutant strain, congenic, targeted mutation
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Strain
MGI:6767318 | C57BL/6JGpt-Cd72<em35Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Genotype
Genotype
Symbol: Cd72/Cd72
Background: either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6)
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd72/Cd72 Fas/Fas
Background: involves: C57BL/6 * C57BL/6JJmsSlc * MRL/Mp
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd72/Cd72 Fas/Fas
Background: involves: C57BL/6 * C57BL/6JJmsSlc * MRL/Mp
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd72/Cd72 Fas/Fas
Background: involves: C57BL/6J * C57BL/6JJmsSlc * MRL/Mp
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd72/Cd72 Tg(BCL2)22Wehi/?
Background: either: (involves: 129P2/OlaHsd * C57BL/6JWehi * SJL/JWehi) or (involves: 129P2/OlaHsd * C57BL/6 * C57BL/6JWehi * SJL/JWehi)
Zygosity: cx
Has Mutant Allele: true
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Publication
19067131 | -
First Author: Wu HJ
Year: 2009
Journal: J Clin Immunol
Title: CD72, a coreceptor with both positive and negative effects on B lymphocyte development and function.
Volume: 29
Issue: 1
Pages: 12-21
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Protein Domain
IPR039689 | CD72-like
Type: Family
Description: This entry includes CD72 from mammals. Human CD72 is a membrane protein expressed mostly in B cells. It contains a C-type lectin-like domain (CTLD) in the extracellular region and an immunoreceptor tyrosine-based inhibition motif (ITIM) in the cytoplasmic region. It is involved in B-cell proliferation and differentiation []. It plays a role in regulation of the development of systemic lupus erythematosus (SLE), an autoimmune disease characterised by production of autoantibodies to various nuclear components and inflammatory lesions caused by deposition of immune complexes [].
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Publication
11114376 | J:66033
First Author: Shi W
Year: 2000
Journal: Immunity
Title: The class IV semaphorin CD100 plays nonredundant roles in the immune system: defective B and T cell activation in CD100-deficient mice.
Volume: 13
Issue: 5
Pages: 633-42
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Publication
17244710 | J:119492
First Author: Zhu L
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Regulated surface expression and shedding support a dual role for semaphorin 4D in platelet responses to vascular injury.
Volume: 104
Issue: 5
Pages: 1621-6
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Publication
11591755 | J:72060
First Author: Watanabe C
Year: 2001
Journal: J Immunol
Title: Enhanced immune responses in transgenic mice expressing a truncated form of the lymphocyte semaphorin CD100.
Volume: 167
Issue: 8
Pages: 4321-8
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Publication
11641399 | J:73569
First Author: EL-Gazzar MA
Year: 2001
Journal: J Biol Chem
Title: PU.1 is involved in the regulation of B lineage-associated and developmental stage-dependent expression of the germinal center-associated DNA primase GANP.
Volume: 276
Issue: 51
Pages: 48000-8
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Publication
7527741 | J:22254
First Author: Plater-Zyberk C
Year: 1994
Journal: Clin Exp Immunol
Title: Anti-CD5 therapy decreases severity of established disease in collagen type II-induced arthritis in DBA/1 mice.
Volume: 98
Issue: 3
Pages: 442-7
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Publication
17312134 | J:144109
First Author: Sato M
Year: 2007
Journal: J Immunol
Title: Augmentation of signaling through BCR containing IgE but not that containing IgA due to lack of CD22-mediated signal regulation.
Volume: 178
Issue: 5
Pages: 2901-7
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Publication
30930899 | J:277698
 
First Author: Hayakawa K
Year: 2019
Journal: Front Immunol
Title: Crucial Role of Increased Arid3a at the Pre-B and Immature B Cell Stages for B1a Cell Generation.
Volume: 10
Pages: 457
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Protein
A0A494B9V0
Organism: Mus musculus/domesticus
Length: 129  
Fragment?: true
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Publication
2538832 | -
First Author: Dangott LJ
Year: 1989
Journal: Proc Natl Acad Sci U S A
Title: Cloning of the mRNA for the protein that crosslinks to the egg peptide speract.
Volume: 86
Issue: 7
Pages: 2128-32
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Publication
3093892 | -
First Author: Jones NH
Year: 1986
Journal: Nature
Title: Isolation of complementary DNA clones encoding the human lymphocyte glycoprotein T1/Leu-1.
Volume: 323
Issue: 6086
Pages: 346-9
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Publication
1711157 | -
First Author: Van de Velde H
Year: 1991
Journal: Nature
Title: The B-cell surface protein CD72/Lyb-2 is the ligand for CD5.
Volume: 351
Issue: 6328
Pages: 662-5
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Protein Domain
IPR003566 | Tcell_CD5
Type: Family
Description: The egg peptide speract receptor is a transmembrane glycoprotein of about500 amino acids []. Topologically, it comprises a large extracellulardomain of about 450 residues, followed by a transmembrane domain and ashort cytoplasmic region of about 12 amino acids. The extracellulardomain contains 4 repeats of a well-conserved region, which spans 115amino acids and contains 6 conserved cysteines. A similar domain is alsofound towards the C terminus of macrophage scavenger receptor type I [],a membrane glycoprotein implicated in the pathologic deposition ofcholesterol in arterial walls during artherogenesis, and in the CD5glycoprotein, which acts as a receptor in regulating T-cell proliferation.The T1/Leu-1/CD5 glycoprotein is expressed at the surface membrane of allmature T cells. It has been implicated both in the proliferative response of activated T cells and in T-cell helper function []. Thecomplete amino-acid sequence of the T1 precursor has been deduced from cDNAclones. The protein contains a classical signal peptide; a 347-residue extracellular segment; a transmembrane region; and a 93-residue intra-cellular segment []. The extracellular region contains several cysteineresidues and comprises 2 speract receptor domains separated by a proline/threonine-rich region []. CD5 has been shown to function as a receptor,delivering co-stimulatory signals to T-cells, interacting specifically withthe cell-surface protein CD72 (Lyb-2 in mice) exclusive to B-cells [].
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Protein
Q8CIY0
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: false
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Publication
15123656 | J:91678
First Author: Gange CT
Year: 2004
Journal: J Biol Chem
Title: Characterization of sugar binding by osteoclast inhibitory lectin.
Volume: 279
Issue: 28
Pages: 29043-9
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Publication
11323699 | -
First Author: Li P
Year: 2001
Journal: Nat Immunol
Title: Complex structure of the activating immunoreceptor NKG2D and its MHC class I-like ligand MICA.
Volume: 2
Issue: 5
Pages: 443-51
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Publication
15695803 | -
First Author: Park H
Year: 2005
Journal: J Biol Chem
Title: The 1.4 angstrom crystal structure of the human oxidized low density lipoprotein receptor lox-1.
Volume: 280
Issue: 14
Pages: 13593-9
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Publication
11470510 | J:71367
First Author: Yokota K
Year: 2001
Journal: Gene
Title: Identification of a human homologue of the dendritic cell-associated C-type lectin-1, dectin-1.
Volume: 272
Issue: 1-2
Pages: 51-60
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Publication
9765598 | J:49592
First Author: Lamers MB
Year: 1998
Journal: Biochim Biophys Acta
Title: Human MAFA has alternatively spliced variants.
Volume: 1399
Issue: 2-3
Pages: 209-12
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Publication
16341139 | -
First Author: Brown GD
Year: 2006
Journal: Nat Rev Immunol
Title: Dectin-1: a signalling non-TLR pattern-recognition receptor.
Volume: 6
Issue: 1
Pages: 33-43
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Publication
12217400 | -
First Author: Abramson J
Year: 2002
Journal: Mol Immunol
Title: An unusual inhibitory receptor--the mast cell function-associated antigen (MAFA).
Volume: 38
Issue: 16-18
Pages: 1307-13
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Protein Domain
IPR033992 | NKR-like_CTLD
Type: Domain
Description: This entry represents a C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs), including proteins similar to oxidized low density lipoprotein (OxLDL) receptor (LOX-1), CD94, CD69, NKG2-A and -D, osteoclast inhibitory lectin (OCIL), dendritic cell-associated C-type lectin-1 (dectin-1), human myeloid inhibitory C-type lectin-like receptor (MICL), mast cell-associated functional antigen (MAFA), killer cell lectin-like receptors: subfamily F, member 1 (KLRF1) and subfamily B, member 1 (KLRB1), and lys49 receptors. CTLD refers to a domain homologous to the carbohydrate-recognition domains (CRDs) of the C-type lectins [].NKRs are variously associated with activation or inhibition of natural killer (NK) cells. Activating NKRs stimulate cytolysis by NK cells of virally infected or transformed cells; inhibitory NKRs block cytolysis upon recognition of markers of healthy self cells. Most Lys49 receptors are inhibitory; some are stimulatory. OCIL inhibits NK cell function via binding to the receptor NKRP1D. Murine OCIL in addition to inhibiting NK cell function inhibits osteoclast differentiation []. MAFA clusters with the type I Fc epsilon receptor (FcepsilonRI) and inhibits the mast cells secretory response to FcepsilonRI stimulus [, ]. CD72 is a regulator of B cell receptor signaling []. NKG2D is an activating receptor for stress-induced antigens; human NKG2D ligands include the stress induced MHC-I homologs, MICA, MICB, and ULBP family of glycoproteins. Several NKRs have a carbohydrate-binding capacity which is not mediated through calcium ions (e.g. OCIL binds a range of high molecular weight sulfated glycosaminoglycans including dextran sulfate, fucoidan, and gamma-carrageenan sugars) []. Dectin-1 binds fungal beta-glucans and is involved in the innate immune responses to fungal pathogens [, ]. MAFA binds saccharides having terminal alpha-D mannose residues in a calcium-dependent manner. LOX-1 is the major receptor for OxLDL in endothelial cells and thought to play a role in the pathology of atherosclerosis []. Some NKRs exist as homodimers (e.g.Lys49, NKG2D, CD69, LOX-1) and some as heterodimers (e.g. CD94/NKG2A). Dectin-1 can function as a monomer in vitro.
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Protein
P13379
Organism: Mus musculus/domesticus
Length: 494  
Fragment?: false
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Publication
1978939 | J:10839
First Author: Freeman M
Year: 1990
Journal: Proc Natl Acad Sci U S A
Title: An ancient, highly conserved family of cysteine-rich protein domains revealed by cloning type I and type II murine macrophage scavenger receptors.
Volume: 87
Issue: 22
Pages: 8810-4
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Protein
Q91X69
Organism: Mus musculus/domesticus
Length: 494  
Fragment?: false
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Protein
Q3UP78
Organism: Mus musculus/domesticus
Length: 494  
Fragment?: false
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Protein
Q9ER20
Organism: Mus musculus/domesticus
Length: 494  
Fragment?: false
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Protein
Q8C9H0
Organism: Mus musculus/domesticus
Length: 352  
Fragment?: true
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Protein
A0A494BB49
Organism: Mus musculus/domesticus
Length: 449  
Fragment?: false
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Protein
Q60653
Organism: Mus musculus/domesticus
Length: 266  
Fragment?: false
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Protein
P27811
Organism: Mus musculus/domesticus
Length: 227  
Fragment?: false
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Protein
P37217
Organism: Mus musculus/domesticus
Length: 199  
Fragment?: false
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Protein
Q9EQ09
Organism: Mus musculus/domesticus
Length: 363  
Fragment?: false
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Protein
Q60654
Organism: Mus musculus/domesticus
Length: 280  
Fragment?: false
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Protein
O54707
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: false
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Protein
P27814
Organism: Mus musculus/domesticus
Length: 223  
Fragment?: false
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Protein
Q60652
Organism: Mus musculus/domesticus
Length: 266  
Fragment?: false
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Protein
Q60682
Organism: Mus musculus/domesticus
Length: 266  
Fragment?: false
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Protein
Q60660
Organism: Mus musculus/domesticus
Length: 288  
Fragment?: false
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Protein
Q64329
Organism: Mus musculus/domesticus
Length: 266  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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