Type |
Details |
Score |
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Allele |
Name: |
leptin receptor; targeted mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, Inducible, Recombinase |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
131
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
108
|
Fragment?: |
false |
|
•
•
•
•
•
|
Allele |
Name: |
leptin receptor; endonuclease-mediated mutation 3, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
leptin receptor; mutation 1, Cecilia Lo |
Allele Type: |
Spontaneous |
Attribute String: |
Not Specified |
|
•
•
•
•
•
|
Allele |
Name: |
leptin receptor; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Inducible, Recombinase |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Allele |
Name: |
leptin receptor; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Inducible, Recombinase |
|
•
•
•
•
•
|
Allele |
Name: |
leptin receptor; endonuclease-mediated mutation 4, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Inducible, Recombinase |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant stock, spontaneous mutation |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Lepr/Lepr |
Background: |
STOCK Lepr/GrsrJ |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
HT Experiment |
Series Id: |
GSE70527 |
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
ArrayExpress |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 1, Gerard Karsenty |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
leptin receptor; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion, Cyagen Biosciences |
Allele Type: |
Transgenic |
Attribute String: |
Inducible, Recombinase |
|
•
•
•
•
•
|
Allele |
Name: |
leptin receptor; adipose |
Allele Type: |
Spontaneous |
|
|
•
•
•
•
•
|
Allele |
Name: |
leptin receptor; mutation 10, Bruce Beutler |
Allele Type: |
Chemically induced (ENU) |
Attribute String: |
Not Specified |
|
•
•
•
•
•
|
Allele |
Name: |
leptin receptor; mutation 8, Bruce Beutler |
Allele Type: |
Chemically induced (ENU) |
Attribute String: |
Not Specified |
|
•
•
•
•
•
|
Allele |
Name: |
leptin receptor; KK |
Allele Type: |
Spontaneous |
|
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion, Ralf H Adams |
Allele Type: |
Transgenic |
Attribute String: |
Inducible, Recombinase |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Tg(Apoe-Lepr)1Kry/? |
Background: |
involves: C57BL/6J |
Zygosity: |
ot |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Lepr/Lepr |
Background: |
Not Specified |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
Strain |
Attribute String: |
chemically induced mutation, coisogenic, mutant strain |
|
•
•
•
•
•
|
Allele |
Name: |
leptin receptor; diabetes 3 Jackson |
Allele Type: |
Spontaneous |
|
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant strain, spontaneous mutation |
|
•
•
•
•
•
|
Strain |
Attribute String: |
spontaneous mutation, mutant strain, congenic |
|
•
•
•
•
•
|
Strain |
Attribute String: |
chemically induced mutation, coisogenic, mutant strain |
|
•
•
•
•
•
|
Allele |
Name: |
leptin receptor; mutation 9, Bruce Beutler |
Allele Type: |
Chemically induced (ENU) |
Attribute String: |
Not Specified |
|
•
•
•
•
•
|
Strain |
Attribute String: |
chemically induced mutation, coisogenic, mutant strain |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Lepr/Lepr |
Background: |
129P3/J-Lepr/J |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Lepr/Lepr |
Background: |
B6.129-Lepr |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Lepr/Lepr |
Background: |
involves: C57BL/6J * KK/HlLt |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Lepr/Lepr |
Background: |
C57BL/6J-Lepr |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Lepr/Lepr |
Background: |
C57BL/6J-Lepr |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Lepr/Lepr |
Background: |
C57BL/6J-Lepr |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
HT Experiment |
Series Id: |
GSE12209 |
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
ArrayExpress |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion, Xiang-Hang Luo |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Lep/Lep<+> Tg(Apoe-Lepr)1Kry/? |
Background: |
involves: C57BL/6J |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Elefteriou F |
Year: |
2004 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Serum leptin level is a regulator of bone mass. |
Volume: |
101 |
Issue: |
9 |
Pages: |
3258-63 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Lepr-cre/ERT2)#Rha/? |
Background: |
involves: 129S1/Sv * 129X1/SvJ |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Lepr-cre/ERT2)#Cya/? Tg(Col1a1*2.3-GFP)1Rowe/? |
Background: |
involves: 129S6/SvEvTac * C57BL/6 * CD-1 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Lepr/Lepr<+> |
Background: |
involves: 129S6/SvEvTac * C57BL/6NCrl |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim KW |
Year: |
2011 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Steroidogenic factor 1 directs programs regulating diet-induced thermogenesis and leptin action in the ventral medial hypothalamic nucleus. |
Volume: |
108 |
Issue: |
26 |
Pages: |
10673-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wijesuriya TM |
Year: |
2017 |
Journal: |
Hum Mol Genet |
Title: |
The Prader-Willi syndrome proteins MAGEL2 and necdin regulate leptin receptor cell surface abundance through ubiquitination pathways. |
Volume: |
26 |
Issue: |
21 |
Pages: |
4215-4230 |
|
•
•
•
•
•
|
Publication |
First Author: |
He Q |
Year: |
2017 |
Journal: |
Stem Cells |
Title: |
Enhanced Hematopoietic Stem Cell Self-Renewal-Promoting Ability of Clonal Primary Mesenchymal Stromal/Stem cells Versus Their Osteogenic Progeny. |
Volume: |
35 |
Issue: |
2 |
Pages: |
473-484 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Lepr/Lepr<+> Tg(Col1a1*2.3-GFP)1Rowe/? |
Background: |
involves: 129S6/SvEvTac * C57BL/6NCrl |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Bryzgalova G |
Year: |
2006 |
Journal: |
Diabetologia |
Title: |
Evidence that oestrogen receptor-alpha plays an important role in the regulation of glucose homeostasis in mice: insulin sensitivity in the liver. |
Volume: |
49 |
Issue: |
3 |
Pages: |
588-97 |
|
•
•
•
•
•
|
Publication |
First Author: |
Qiu Z |
Year: |
2013 |
Journal: |
Nucleic Acids Res |
Title: |
High-efficiency and heritable gene targeting in mouse by transcription activator-like effector nucleases. |
Volume: |
41 |
Issue: |
11 |
Pages: |
e120 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cravo RM |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Leptin signaling in Kiss1 neurons arises after pubertal development. |
Volume: |
8 |
Issue: |
3 |
Pages: |
e58698 |
|
•
•
•
•
•
|
Publication |
First Author: |
Koga S |
Year: |
2014 |
Journal: |
Neurobiol Dis |
Title: |
Effects of diet-induced obesity and voluntary exercise in a tauopathy mouse model: implications of persistent hyperleptinemia and enhanced astrocytic leptin receptor expression. |
Volume: |
71 |
|
Pages: |
180-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gong L |
Year: |
2008 |
Journal: |
Endocrinology |
Title: |
Signal transducer and activator of transcription-3 is required in hypothalamic agouti-related protein/neuropeptide Y neurons for normal energy homeostasis. |
Volume: |
149 |
Issue: |
7 |
Pages: |
3346-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Teixeira PDS |
Year: |
2019 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
Central growth hormone action regulates metabolism during pregnancy. |
Volume: |
317 |
Issue: |
5 |
Pages: |
E925-E940 |
|
•
•
•
•
•
|
Publication |
First Author: |
Várhelyi ZP |
Year: |
2017 |
Journal: |
Front Neurosci |
Title: |
Adiponectin Receptors Are Less Sensitive to Stress in a Transgenic Mouse Model of Alzheimer's Disease. |
Volume: |
11 |
|
Pages: |
199 |
|
•
•
•
•
•
|
Publication |
First Author: |
Arimura N |
Year: |
2004 |
Journal: |
J Biol Chem |
Title: |
The peroxisome proliferator-activated receptor gamma regulates expression of the perilipin gene in adipocytes. |
Volume: |
279 |
Issue: |
11 |
Pages: |
10070-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
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•
•
•
•
•
|