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Search results 101 to 200 out of 232 for Eif2a

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Type Details Score
Publication
27939583 | J:325327
First Author: Rittiner JE
Year: 2016
Journal: Neuron
Title: Functional Genomic Analyses of Mendelian and Sporadic Disease Identify Impaired eIF2α Signaling as a Generalizable Mechanism for Dystonia.
Volume: 92
Issue: 6
Pages: 1238-1251
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Publication
23886890 | J:200077
First Author: Huang ML
Year: 2013
Journal: Am J Pathol
Title: Molecular and functional alterations in a mouse cardiac model of Friedreich ataxia: activation of the integrated stress response, eIF2α phosphorylation, and the induction of downstream targets.
Volume: 183
Issue: 3
Pages: 745-57
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Publication
18996085 | J:143177
First Author: Alves VS
Year: 2009
Journal: Biochem Biophys Res Commun
Title: GCN2 activation and eIF2alpha phosphorylation in the maturation of mouse oocytes.
Volume: 378
Issue: 1
Pages: 41-4
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Publication
22705549 | J:185968
First Author: Emara MM
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Hydrogen peroxide induces stress granule formation independent of eIF2α phosphorylation.
Volume: 423
Issue: 4
Pages: 763-9
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Publication
26487695 | J:230845
First Author: Miyake M
Year: 2016
Journal: FASEB J
Title: Skeletal muscle-specific eukaryotic translation initiation factor 2α phosphorylation controls amino acid metabolism and fibroblast growth factor 21-mediated non-cell-autonomous energy metabolism.
Volume: 30
Issue: 2
Pages: 798-812
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Publication
22355666 | J:206118
 
First Author: Ghosh HS
Year: 2011
Journal: Sci Rep
Title: SIRT1 associates with eIF2-alpha and regulates the cellular stress response.
Volume: 1
Pages: 150
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Publication
18522833 | J:137055
First Author: Oyadomari S
Year: 2008
Journal: Cell Metab
Title: Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice.
Volume: 7
Issue: 6
Pages: 520-32
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Publication
18852460 | J:141100
First Author: Bobrovnikova-Marjon E
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation.
Volume: 105
Issue: 42
Pages: 16314-9
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Publication
22718973 | J:199701
First Author: Fujimura K
Year: 2012
Journal: Nucleic Acids Res
Title: Selenite targets eIF4E-binding protein-1 to inhibit translation initiation and induce the assembly of non-canonical stress granules.
Volume: 40
Issue: 16
Pages: 8099-110
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Publication
25921292 | J:260170
First Author: Chaveroux C
Year: 2015
Journal: Sci Signal
Title: In vivo imaging of the spatiotemporal activity of the eIF2α-ATF4 signaling pathway: Insights into stress and related disorders.
Volume: 8
Issue: 374
Pages: rs5
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Publication
29449538 | J:319302
First Author: Krishnamoorthy J
Year: 2018
Journal: Cell Death Dis
Title: Downregulation of PERK activity and eIF2α serine 51 phosphorylation by mTOR complex 1 elicits pro-oxidant and pro-death effects in tuberous sclerosis-deficient cells.
Volume: 9
Issue: 3
Pages: 254
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Publication
29698569 | J:325844
First Author: Xu X
Year: 2018
Journal: Hepatology
Title: Preemptive Activation of the Integrated Stress Response Protects Mice From Diet-Induced Obesity and Insulin Resistance by Fibroblast Growth Factor 21 Induction.
Volume: 68
Issue: 6
Pages: 2167-2181
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Publication
23624402 | J:198492
First Author: Han J
Year: 2013
Journal: Nat Cell Biol
Title: ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death.
Volume: 15
Issue: 5
Pages: 481-90
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Publication
29449374 | J:262786
First Author: Nikonorova IA
Year: 2018
Journal: J Biol Chem
Title: Time-resolved analysis of amino acid stress identifies eIF2 phosphorylation as necessary to inhibit mTORC1 activity in liver.
Volume: 293
Issue: 14
Pages: 5005-5015
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Publication
18052927 | J:132301
First Author: Gomez E
Year: 2008
Journal: Biochem J
Title: A decrease in cellular energy status stimulates PERK-dependent eIF2alpha phosphorylation and regulates protein synthesis in pancreatic beta-cells.
Volume: 410
Issue: 3
Pages: 485-93
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Publication
18287093 | J:136544
First Author: Thiaville MM
Year: 2008
Journal: J Biol Chem
Title: MEK signaling is required for phosphorylation of eIF2alpha following amino acid limitation of HepG2 human hepatoma cells.
Volume: 283
Issue: 16
Pages: 10848-57
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Publication
27802424 | J:309341
First Author: Stone S
Year: 2016
Journal: Oncotarget
Title: Dual role of the integrated stress response in medulloblastoma tumorigenesis.
Volume: 7
Issue: 39
Pages: 64124-64135
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Publication
26039714 | J:319163
First Author: Li H
Year: 2015
Journal: Cell Cycle
Title: Administration of progranulin (PGRN) triggers ER stress and impairs insulin sensitivity via PERK-eIF2α-dependent manner.
Volume: 14
Issue: 12
Pages: 1893-907
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Publication
22242125 | J:190264
First Author: Alter J
Year: 2011
Journal: PLoS One
Title: Stress-induced C/EBP homology protein (CHOP) represses MyoD transcription to delay myoblast differentiation.
Volume: 6
Issue: 12
Pages: e29498
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Publication
19181853 | J:144954
First Author: Harding HP
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2alpha) dephosphorylation in mammalian development.
Volume: 106
Issue: 6
Pages: 1832-7
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Publication
28726788 | J:274493
First Author: Huang H
Year: 2017
Journal: Cell Death Dis
Title: Neuroprotection by eIF2α-CHOP inhibition and XBP-1 activation in EAE/optic neuritiss.
Volume: 8
Issue: 7
Pages: e2936
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Publication
16705175 | J:109619
First Author: Hori O
Year: 2006
Journal: Mol Cell Biol
Title: Deletion of SERP1/RAMP4, a component of the endoplasmic reticulum (ER) translocation sites, leads to ER stress.
Volume: 26
Issue: 11
Pages: 4257-67
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Publication
38159280 | J:346137
First Author: Amiri M
Year: 2024
Journal: Cell Rep
Title: Impact of eIF2α phosphorylation on the translational landscape of mouse embryonic stem cells.
Volume: 43
Issue: 1
Pages: 113615
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Publication
23000413 | J:190089
First Author: Kimball SR
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Induction of REDD1 gene expression in the liver in response to endoplasmic reticulum stress is mediated through a PERK, eIF2α phosphorylation, ATF4-dependent cascade.
Volume: 427
Issue: 3
Pages: 485-9
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Publication
21135100 | J:169485
First Author: Saito A
Year: 2011
Journal: J Biol Chem
Title: Endoplasmic reticulum stress response mediated by the PERK-eIF2(alpha)-ATF4 pathway is involved in osteoblast differentiation induced by BMP2.
Volume: 286
Issue: 6
Pages: 4809-18
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Publication
20434207 | J:167951
First Author: Tcherkezian J
Year: 2010
Journal: Cell
Title: Transmembrane receptor DCC associates with protein synthesis machinery and regulates translation.
Volume: 141
Issue: 4
Pages: 632-44
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22215619 | J:183720
First Author: Majumder M
Year: 2012
Journal: Mol Cell Biol
Title: A novel feedback loop regulates the response to endoplasmic reticulum stress via the cooperation of cytoplasmic splicing and mRNA translation.
Volume: 32
Issue: 5
Pages: 992-1003
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Publication
22959274 | J:191802
First Author: Suraweera A
Year: 2012
Journal: Mol Cell
Title: Failure of amino acid homeostasis causes cell death following proteasome inhibition.
Volume: 48
Issue: 2
Pages: 242-53
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Publication
22833567 | J:199668
First Author: Reineke LC
Year: 2012
Journal: Mol Biol Cell
Title: Large G3BP-induced granules trigger eIF2α phosphorylation.
Volume: 23
Issue: 18
Pages: 3499-510
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Publication
29555819 | J:317070
First Author: Luo L
Year: 2018
Journal: J Mol Endocrinol
Title: De-silencing Grb10 contributes to acute ER stress-induced steatosis in mouse liver.
Volume: 60
Issue: 4
Pages: 285-297
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Publication
20660158 | J:182847
First Author: Muaddi H
Year: 2010
Journal: Mol Biol Cell
Title: Phosphorylation of eIF2α at serine 51 is an important determinant of cell survival and adaptation to glucose deficiency.
Volume: 21
Issue: 18
Pages: 3220-31
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Publication
21385877 | J:171119
First Author: Peña J
Year: 2011
Journal: J Biol Chem
Title: Dengue virus modulates the unfolded protein response in a time-dependent manner.
Volume: 286
Issue: 16
Pages: 14226-36
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Publication
23314846 | J:195432
First Author: Han J
Year: 2013
Journal: Diabetologia
Title: ER stress signalling through eIF2α and CHOP, but not IRE1α, attenuates adipogenesis in mice.
Volume: 56
Issue: 4
Pages: 911-24
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Publication
24204775 | J:209179
First Author: Panzhinskiy E
Year: 2013
Journal: PLoS One
Title: Protein tyrosine phosphatase 1B and insulin resistance: role of endoplasmic reticulum stress/reactive oxygen species/nuclear factor kappa B axis.
Volume: 8
Issue: 10
Pages: e77228
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7519779 | J:19621
First Author: Ito T
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Interleukin 3 stimulates protein synthesis by regulating double-stranded RNA-dependent protein kinase.
Volume: 91
Issue: 16
Pages: 7455-9
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15544353 | J:93997
First Author: Datta B
Year: 2004
Journal: Biochemistry
Title: Treatment of cells with the angiogenic inhibitor fumagillin results in increased stability of eukaryotic initiation factor 2-associated glycoprotein, p67, and reduced phosphorylation of extracellular signal-regulated kinases.
Volume: 43
Issue: 46
Pages: 14821-31
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Publication
20924113 | J:165561
First Author: Papadakis AI
Year: 2010
Journal: Cancer Res
Title: eIF2{alpha} Kinase PKR modulates the hypoxic response by Stat3-dependent transcriptional suppression of HIF-1{alpha}.
Volume: 70
Issue: 20
Pages: 7820-9
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Publication
21044701 | J:168632
First Author: Firtina Z
Year: 2011
Journal: Gene Expr Patterns
Title: Unfolded Protein Response (UPR) is activated during normal lens development.
Volume: 11
Issue: 1-2
Pages: 135-43
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19861488 | J:162904
First Author: Yamaji M
Year: 2010
Journal: Reproduction
Title: Functional reconstruction of NANOS3 expression in the germ cell lineage by a novel transgenic reporter reveals distinct subcellular localizations of NANOS3.
Volume: 139
Issue: 2
Pages: 381-93
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24332809 | J:206302
First Author: Saito A
Year: 2014
Journal: Mol Cell
Title: Chondrocyte proliferation regulated by secreted luminal domain of ER stress transducer BBF2H7/CREB3L2.
Volume: 53
Issue: 1
Pages: 127-39
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35588739 | J:326215
First Author: Eisenstein A
Year: 2022
Journal: Immunity
Title: Activation of the transcription factor NRF2 mediates the anti-inflammatory properties of a subset of over-the-counter and prescription NSAIDs.
Volume: 55
Issue: 6
Pages: 1082-1095.e5
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33361822 | J:305864
First Author: Kalish BT
Year: 2021
Journal: Nat Neurosci
Title: Maternal immune activation in mice disrupts proteostasis in the fetal brain.
Volume: 24
Issue: 2
Pages: 204-213
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23350942 | J:213107
First Author: Sayano T
Year: 2013
Journal: FEBS J
Title: L-serine deficiency caused by genetic Phgdh deletion leads to robust induction of 4E-BP1 and subsequent repression of translation initiation in the developing central nervous system.
Volume: 280
Issue: 6
Pages: 1502-17
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19911006 | J:171795
First Author: Ishigaki S
Year: 2010
Journal: Cell Death Differ
Title: AATF mediates an antiapoptotic effect of the unfolded protein response through transcriptional regulation of AKT1.
Volume: 17
Issue: 5
Pages: 774-86
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17913437 | J:128422
First Author: Zhang X
Year: 2007
Journal: Int J Dev Neurosci
Title: Endoplasmic reticulum stress during the embryonic development of the central nervous system in the mouse.
Volume: 25
Issue: 7
Pages: 455-63
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19805353 | J:153222
First Author: Iwawaki T
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability.
Volume: 106
Issue: 39
Pages: 16657-62
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Publication
27130031 | J:315123
 
First Author: Zhong J
Year: 2016
Journal: Free Radic Biol Med
Title: Superoxide dismutase 2 overexpression alleviates maternal diabetes-induced neural tube defects, restores mitochondrial function and suppresses cellular stress in diabetic embryopathy.
Volume: 96
Pages: 234-44
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27912058 | J:238065
First Author: Tărlungeanu DC
Year: 2016
Journal: Cell
Title: Impaired Amino Acid Transport at the Blood Brain Barrier Is a Cause of Autism Spectrum Disorder.
Volume: 167
Issue: 6
Pages: 1481-1494.e18
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22961085 | J:208480
First Author: Li X
Year: 2013
Journal: Diabetes
Title: c-Jun NH2-terminal kinase 1/2 and endoplasmic reticulum stress as interdependent and reciprocal causation in diabetic embryopathy.
Volume: 62
Issue: 2
Pages: 599-608
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36227697 | J:332218
 
First Author: Sallais J
Year: 2022
Journal: JCI Insight
Title: HIF1 inhibitor acriflavine rescues early-onset preeclampsia phenotype in mice lacking placental prolyl hydroxylase domain protein 2.
Volume: 7
Issue: 23
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36154620 | J:335524
First Author: Zhu S
Year: 2022
Journal: Circulation
Title: Mitochondrial Stress Induces an HRI-eIF2α Pathway Protective for Cardiomyopathy.
Volume: 146
Issue: 13
Pages: 1028-1031
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26925839 | J:320375
First Author: Mirigian LS
Year: 2016
Journal: J Bone Miner Res
Title: Osteoblast Malfunction Caused by Cell Stress Response to Procollagen Misfolding in α2(I)-G610C Mouse Model of Osteogenesis Imperfecta.
Volume: 31
Issue: 8
Pages: 1608-1616
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28396396 | J:242134
First Author: Zhao Z
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Formation of neurodegenerative aggresome and death-inducing signaling complex in maternal diabetes-induced neural tube defects.
Volume: 114
Issue: 17
Pages: 4489-4494
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19767744 | J:158241
First Author: Saito A
Year: 2009
Journal: Nat Cell Biol
Title: Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis.
Volume: 11
Issue: 10
Pages: 1197-204
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32853550 | J:297745
First Author: Kapur M
Year: 2020
Journal: Neuron
Title: Expression of the Neuronal tRNA n-Tr20 Regulates Synaptic Transmission and Seizure Susceptibility.
Volume: 108
Issue: 1
Pages: 193-208.e9
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37998373 | J:342871
 
First Author: Xiang J
Year: 2023
Journal: Cells
Title: ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment.
Volume: 12
Issue: 22
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32005751 | J:287361
 
First Author: Pakarinen E
Year: 2020
Journal: eNeuro
Title: MANF Ablation Causes Prolonged Activation of the UPR without Neurodegeneration in the Mouse Midbrain Dopamine System.
Volume: 7
Issue: 1
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27626668 | J:238993
First Author: Kaneko K
Year: 2016
Journal: Cell Rep
Title: Neuronal Rap1 Regulates Energy Balance, Glucose Homeostasis, and Leptin Actions.
Volume: 16
Issue: 11
Pages: 3003-3015
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19858219 | J:158314
First Author: Firtina Z
Year: 2009
Journal: J Biol Chem
Title: Abnormal expression of collagen IV in lens activates unfolded protein response resulting in cataract.
Volume: 284
Issue: 51
Pages: 35872-84
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18228065 | J:241343
First Author: Furuya S
Year: 2008
Journal: Funct Integr Genomics
Title: Inactivation of the 3-phosphoglycerate dehydrogenase gene in mice: changes in gene expression and associated regulatory networks resulting from serine deficiency.
Volume: 8
Issue: 3
Pages: 235-49
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33060561 | J:313943
First Author: Cao S
Year: 2020
Journal: Cell Death Dis
Title: Restoring BMP4 expression in vascular endothelial progenitors ameliorates maternal diabetes-induced apoptosis and neural tube defects.
Volume: 11
Issue: 10
Pages: 859
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38266827 | J:345131
 
First Author: Schraps N
Year: 2024
Journal: Free Radic Biol Med
Title: Cardiomyocyte maturation alters molecular stress response capacities and determines cell survival upon mitochondrial dysfunction.
Volume: 213
Pages: 248-265
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30635284 | J:272566
 
First Author: Yang R
Year: 2019
Journal: Development
Title: CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development.
Volume: 146
Issue: 2
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25157170 | J:216392
First Author: Kraushar ML
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Temporally defined neocortical translation and polysome assembly are determined by the RNA-binding protein Hu antigen R.
Volume: 111
Issue: 36
Pages: E3815-24
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31789450 | J:282947
First Author: Poncet N
Year: 2020
Journal: EMBO Rep
Title: Wnt regulates amino acid transporter Slc7a5 and so constrains the integrated stress response in mouse embryos.
Volume: 21
Issue: 1
Pages: e48469
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28474670 | J:250342
 
First Author: Wang F
Year: 2017
Journal: Nat Commun
Title: Protein kinase C-alpha suppresses autophagy and induces neural tube defects via miR-129-2 in diabetic pregnancy.
Volume: 8
Pages: 15182
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26651292 | J:240003
First Author: Laguesse S
Year: 2015
Journal: Dev Cell
Title: A Dynamic Unfolded Protein Response Contributes to the Control of Cortical Neurogenesis.
Volume: 35
Issue: 5
Pages: 553-67
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27106802 | J:253948
 
First Author: Magarin M
Year: 2016
Journal: J Mol Cell Cardiol
Title: Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stress.
Volume: 97
Pages: 1-14
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30655546 | J:270211
First Author: Yang P
Year: 2019
Journal: Nat Commun
Title: Tip60- and sirtuin 2-regulated MARCKS acetylation and phosphorylation are required for diabetic embryopathy.
Volume: 10
Issue: 1
Pages: 282
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37812701 | J:342544
First Author: Radzishevsky I
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Impairment of serine transport across the blood-brain barrier by deletion of Slc38a5 causes developmental delay and motor dysfunction.
Volume: 120
Issue: 42
Pages: e2302780120
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19139267 | J:146172
First Author: Wang X
Year: 2009
Journal: J Cell Biol
Title: Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant mice.
Volume: 184
Issue: 1
Pages: 143-58
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26494538 | J:237614
 
First Author: Zhu M
Year: 2015
Journal: Sci Rep
Title: Neural tube opening and abnormal extraembryonic membrane development in SEC23A deficient mice.
Volume: 5
Pages: 15471
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35377412 | J:333870
First Author: Jazwiec PA
Year: 2022
Journal: Biol Reprod
Title: Paternal obesity induces placental hypoxia and sex-specific impairments in placental vascularization and offspring metabolism†.
Volume: 107
Issue: 2
Pages: 574-589
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27416896 | J:240829
 
First Author: Jiang M
Year: 2016
Journal: Nat Commun
Title: Regulation of PERK-eIF2α signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes.
Volume: 7
Pages: 12185
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Publication
35237793 | J:321836
 
First Author: Zhao K
Year: 2022
Journal: Development
Title: LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development.
Volume: 149
Issue: 6
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12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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- | J:24194
     
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
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- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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