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Search results 1 to 100 out of 121 for Pdk4

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Category: Publication
Type Details Score
Publication
First Author: Pin F
Year: 2019
Journal: FASEB J
Title: PDK4 drives metabolic alterations and muscle atrophy in cancer cachexia.
Volume: 33
Issue: 6
Pages: 7778-7790
Publication
First Author: Hsieh MC
Year: 2008
Journal: J Biol Chem
Title: Regulation of the PDK4 isozyme by the Rb-E2F1 complex.
Volume: 283
Issue: 41
Pages: 27410-7
Publication
First Author: Thoudam T
Year: 2019
Journal: Diabetes
Title: PDK4 Augments ER-Mitochondria Contact to Dampen Skeletal Muscle Insulin Signaling During Obesity.
Volume: 68
Issue: 3
Pages: 571-586
Publication
First Author: Nahlé Z
Year: 2008
Journal: J Biol Chem
Title: CD36-dependent regulation of muscle FoxO1 and PDK4 in the PPAR delta/beta-mediated adaptation to metabolic stress.
Volume: 283
Issue: 21
Pages: 14317-26
Publication
First Author: Kim YD
Year: 2012
Journal: Diabetes
Title: Metformin inhibits growth hormone-mediated hepatic PDK4 gene expression through induction of orphan nuclear receptor small heterodimer partner.
Volume: 61
Issue: 10
Pages: 2484-94
Publication
First Author: Wende AR
Year: 2005
Journal: Mol Cell Biol
Title: PGC-1alpha coactivates PDK4 gene expression via the orphan nuclear receptor ERRalpha: a mechanism for transcriptional control of muscle glucose metabolism.
Volume: 25
Issue: 24
Pages: 10684-94
Publication
First Author: Thoudam T
Year: 2023
Journal: Nat Commun
Title: Enhanced Ca(2+)-channeling complex formation at the ER-mitochondria interface underlies the pathogenesis of alcohol-associated liver disease.
Volume: 14
Issue: 1
Pages: 1703
Publication
First Author: Jeoung NH
Year: 2008
Journal: Am J Physiol Endocrinol Metab
Title: Pyruvate dehydrogenase kinase-4 deficiency lowers blood glucose and improves glucose tolerance in diet-induced obese mice.
Volume: 295
Issue: 1
Pages: E46-54
Publication
First Author: Wang Y
Year: 2012
Journal: Bone
Title: Pyruvate dehydrogenase kinase 4 induces bone loss at unloading by promoting osteoclastogenesis.
Volume: 50
Issue: 1
Pages: 409-19
Publication
First Author: Townsend LK
Year: 2020
Journal: Am J Physiol Cell Physiol
Title: Reactive oxygen species-dependent regulation of pyruvate dehydrogenase kinase-4 in white adipose tissue.
Volume: 318
Issue: 1
Pages: C137-C149
Publication
First Author: Herbst EA
Year: 2014
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Pyruvate dehydrogenase kinase-4 contributes to the recirculation of gluconeogenic precursors during postexercise glycogen recovery.
Volume: 306
Issue: 2
Pages: R102-7
Publication
First Author: Hwang B
Year: 2012
Journal: FEBS J
Title: Additive effects of clofibric acid and pyruvate dehydrogenase kinase isoenzyme 4 (PDK4) deficiency on hepatic steatosis in mice fed a high saturated fat diet.
Volume: 279
Issue: 10
Pages: 1883-93
Publication
First Author: Zhang M
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Pyruvate dehydrogenase kinase 4 mediates lipogenesis and contributes to the pathogenesis of nonalcoholic steatohepatitis.
Volume: 495
Issue: 1
Pages: 582-586
Publication
First Author: Zhang L
Year: 2012
Journal: FEBS Lett
Title: Activating cardiac E2F1 induces up-regulation of pyruvate dehydrogenase kinase 4 in mice on a short term of high fat feeding.
Volume: 586
Issue: 7
Pages: 996-1003
Publication
First Author: Wu P
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Adaptive increase in pyruvate dehydrogenase kinase 4 during starvation is mediated by peroxisome proliferator-activated receptor alpha.
Volume: 287
Issue: 2
Pages: 391-6
Publication
First Author: Khan D
Year: 2018
Journal: J Cell Physiol
Title: SIRT6 deacetylase transcriptionally regulates glucose metabolism in heart.
Volume: 233
Issue: 7
Pages: 5478-5489
Publication  
First Author: Min BK
Year: 2019
Journal: Front Immunol
Title: Pyruvate Dehydrogenase Kinase Is a Metabolic Checkpoint for Polarization of Macrophages to the M1 Phenotype.
Volume: 10
Pages: 944
Publication
First Author: Mori J
Year: 2013
Journal: Am J Physiol Heart Circ Physiol
Title: ANG II causes insulin resistance and induces cardiac metabolic switch and inefficiency: a critical role of PDK4.
Volume: 304
Issue: 8
Pages: H1103-13
Publication
First Author: White UA
Year: 2007
Journal: Diabetes
Title: The STAT5A-mediated induction of pyruvate dehydrogenase kinase 4 expression by prolactin or growth hormone in adipocytes.
Volume: 56
Issue: 6
Pages: 1623-9
Publication
First Author: Takubo K
Year: 2013
Journal: Cell Stem Cell
Title: Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells.
Volume: 12
Issue: 1
Pages: 49-61
Publication
First Author: Jha MK
Year: 2015
Journal: J Neurosci
Title: Metabolic Connection of Inflammatory Pain: Pivotal Role of a Pyruvate Dehydrogenase Kinase-Pyruvate Dehydrogenase-Lactic Acid Axis.
Volume: 35
Issue: 42
Pages: 14353-69
Publication
First Author: Gopal K
Year: 2017
Journal: Am J Physiol Heart Circ Physiol
Title: FoxO1 regulates myocardial glucose oxidation rates via transcriptional control of pyruvate dehydrogenase kinase 4 expression.
Volume: 313
Issue: 3
Pages: H479-H490
Publication
First Author: Klyuyeva A
Year: 2019
Journal: J Biol Chem
Title: Tissue-specific kinase expression and activity regulate flux through the pyruvate dehydrogenase complex.
Volume: 294
Issue: 3
Pages: 838-851
Publication
First Author: Tao R
Year: 2013
Journal: PLoS One
Title: Genetic inactivation of pyruvate dehydrogenase kinases improves hepatic insulin resistance induced diabetes.
Volume: 8
Issue: 8
Pages: e71997
Publication
First Author: Choiniere J
Year: 2017
Journal: Mol Pharmacol
Title: Pyruvate Dehydrogenase Kinase 4 Deficiency Results in Expedited Cellular Proliferation through E2F1-Mediated Increase of Cyclins.
Volume: 91
Issue: 3
Pages: 189-196
Publication
First Author: Wan Z
Year: 2012
Journal: PLoS One
Title: IL-6 indirectly modulates the induction of glyceroneogenic enzymes in adipose tissue during exercise.
Volume: 7
Issue: 7
Pages: e41719
Publication
First Author: Jeoung NH
Year: 2006
Journal: Biochem J
Title: Role of pyruvate dehydrogenase kinase isoenzyme 4 (PDHK4) in glucose homoeostasis during starvation.
Volume: 397
Issue: 3
Pages: 417-25
Publication
First Author: Hwang B
Year: 2009
Journal: Biochem J
Title: Pyruvate dehydrogenase kinase isoenzyme 4 (PDHK4) deficiency attenuates the long-term negative effects of a high-saturated fat diet.
Volume: 423
Issue: 2
Pages: 243-52
Publication  
First Author: Bowker-Kinley M
Year: 1999
Journal: Biochem J
Title: Evidence that pyruvate dehydrogenase kinase belongs to the ATPase/kinase superfamily.
Volume: 344 Pt 1
Pages: 47-53
Publication    
First Author: Horiuchi M
Year: 1998
Journal: GenBank Submission
Title: Mus musculus mRNA for pyruvate dehydrogenase kinase-like protein
Pages: AJ001418
Publication
First Author: Jeoung NH
Year: 2012
Journal: Biochem J
Title: Fasting induces ketoacidosis and hypothermia in PDHK2/PDHK4-double-knockout mice.
Volume: 443
Issue: 3
Pages: 829-39
Publication
First Author: Ussher JR
Year: 2012
Journal: Cardiovasc Res
Title: Stimulation of glucose oxidation protects against acute myocardial infarction and reperfusion injury.
Volume: 94
Issue: 2
Pages: 359-69
Publication
First Author: Yucel N
Year: 2019
Journal: Cell Rep
Title: Glucose Metabolism Drives Histone Acetylation Landscape Transitions that Dictate Muscle Stem Cell Function.
Volume: 27
Issue: 13
Pages: 3939-3955.e6
Publication
First Author: Rahimi Y
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Genetic activation of pyruvate dehydrogenase alters oxidative substrate selection to induce skeletal muscle insulin resistance.
Volume: 111
Issue: 46
Pages: 16508-13
Publication
First Author: Bhusal A
Year: 2021
Journal: Glia
Title: Satellite glia as a critical component of diabetic neuropathy: Role of lipocalin-2 and pyruvate dehydrogenase kinase-2 axis in the dorsal root ganglion.
Volume: 69
Issue: 4
Pages: 971-996
Publication
First Author: Hou X
Year: 2015
Journal: J Cell Sci
Title: Differing roles of pyruvate dehydrogenase kinases during mouse oocyte maturation.
Volume: 128
Issue: 13
Pages: 2319-29
Publication
First Author: Heinemann-Yerushalmi L
Year: 2021
Journal: Dev Cell
Title: BCKDK regulates the TCA cycle through PDC in the absence of PDK family during embryonic development.
Volume: 56
Issue: 8
Pages: 1182-1194.e6
Publication
First Author: Long J
Year: 2016
Journal: J Clin Invest
Title: Long noncoding RNA Tug1 regulates mitochondrial bioenergetics in diabetic nephropathy.
Volume: 126
Issue: 11
Pages: 4205-4218
Publication
First Author: Abbott BD
Year: 2012
Journal: Reprod Toxicol
Title: Effects of perfluorooctanoic acid (PFOA) on expression of peroxisome proliferator-activated receptors (PPAR) and nuclear receptor-regulated genes in fetal and postnatal CD-1 mouse tissues.
Volume: 33
Issue: 4
Pages: 491-505
Publication
First Author: Ono R
Year: 2006
Journal: Nat Genet
Title: Deletion of Peg10, an imprinted gene acquired from a retrotransposon, causes early embryonic lethality.
Volume: 38
Issue: 1
Pages: 101-6
Publication
First Author: Lai L
Year: 2008
Journal: Genes Dev
Title: Transcriptional coactivators PGC-1alpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heart.
Volume: 22
Issue: 14
Pages: 1948-61
Publication
First Author: Chang I
Year: 2013
Journal: J Clin Invest
Title: Endothelin-2 deficiency causes growth retardation, hypothermia, and emphysema in mice.
Volume: 123
Issue: 6
Pages: 2643-53
Publication
First Author: Conrad E
Year: 2016
Journal: Am J Physiol Endocrinol Metab
Title: The MAFB transcription factor impacts islet α-cell function in rodents and represents a unique signature of primate islet β-cells.
Volume: 310
Issue: 1
Pages: E91-E102
Publication
First Author: Iso T
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: Capillary endothelial fatty acid binding proteins 4 and 5 play a critical role in fatty acid uptake in heart and skeletal muscle.
Volume: 33
Issue: 11
Pages: 2549-57
Publication
First Author: Paredes A
Year: 2023
Journal: Nature
Title: Îł-Linolenic acid in maternal milk drives cardiac metabolic maturation.
Volume: 618
Issue: 7964
Pages: 365-373
Publication
First Author: Hyvärinen J
Year: 2010
Journal: J Biol Chem
Title: Hearts of hypoxia-inducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemia-reperfusion injury.
Volume: 285
Issue: 18
Pages: 13646-57
Publication  
First Author: Zhao K
Year: 2022
Journal: Development
Title: LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development.
Volume: 149
Issue: 6
Publication
First Author: Sakamoto T
Year: 2020
Journal: Circ Res
Title: A Critical Role for Estrogen-Related Receptor Signaling in Cardiac Maturation.
Volume: 126
Issue: 12
Pages: 1685-1702
Publication
First Author: Bowman CE
Year: 2016
Journal: Mol Cell Biol
Title: Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.
Volume: 36
Issue: 15
Pages: 2089-104
Publication
First Author: Da Cruz S
Year: 2003
Journal: J Biol Chem
Title: Proteomic analysis of the mouse liver mitochondrial inner membrane.
Volume: 278
Issue: 42
Pages: 41566-71
Publication      
First Author: Elliott R
Year: 2000
Journal: Personal Communication
Title: Chromosome Locations Based on RH mapping
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Mootha VK
Year: 2003
Journal: Cell
Title: Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Volume: 115
Issue: 5
Pages: 629-40
Publication
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Oberhuber M
Year: 2020
Journal: Mol Syst Biol
Title: STAT3-dependent analysis reveals PDK4 as independent predictor of recurrence in prostate cancer.
Volume: 16
Issue: 4
Pages: e9247
Publication
First Author: Newhardt MF
Year: 2019
Journal: J Biol Chem
Title: Enhancing cardiac glycolysis causes an increase in PDK4 content in response to short-term high-fat diet.
Volume: 294
Issue: 45
Pages: 16831-16845
Publication
First Author: Gao Y
Year: 2020
Journal: Gastroenterology
Title: LKB1 Represses ATOH1 via PDK4 and Energy Metabolism and Regulates Intestinal Stem Cell Fate.
Volume: 158
Issue: 5
Pages: 1389-1401.e10
Publication
First Author: Ushikai M
Year: 2011
Journal: Mol Genet Metab
Title: Induction of PDK4 in the heart muscle of JVS mice, an animal model of systemic carnitine deficiency, does not appear to reduce glucose utilization by the heart.
Volume: 102
Issue: 3
Pages: 349-55
Publication
First Author: Liu Z
Year: 2014
Journal: J Biol Chem
Title: PDK4 protein promotes tumorigenesis through activation of cAMP-response element-binding protein (CREB)-Ras homolog enriched in brain (RHEB)-mTORC1 signaling cascade.
Volume: 289
Issue: 43
Pages: 29739-49
Publication
First Author: Zhao G
Year: 2008
Journal: Am J Physiol Heart Circ Physiol
Title: Overexpression of pyruvate dehydrogenase kinase 4 in heart perturbs metabolism and exacerbates calcineurin-induced cardiomyopathy.
Volume: 294
Issue: 2
Pages: H936-43
Publication
First Author: Horiuchi M
Year: 1999
Journal: Biofactors
Title: Pyruvate dehydrogenase kinase 4 mRNA is increased in the hypertrophied ventricles of carnitine-deficient juvenile visceral steatosis (JVS) mice.
Volume: 10
Issue: 2-3
Pages: 301-9
Publication
First Author: Dyar KA
Year: 2014
Journal: Mol Metab
Title: Muscle insulin sensitivity and glucose metabolism are controlled by the intrinsic muscle clock.
Volume: 3
Issue: 1
Pages: 29-41
Publication
First Author: Degenhardt T
Year: 2007
Journal: J Mol Biol
Title: Three members of the human pyruvate dehydrogenase kinase gene family are direct targets of the peroxisome proliferator-activated receptor beta/delta.
Volume: 372
Issue: 2
Pages: 341-55
Publication
First Author: Chambers KT
Year: 2011
Journal: J Biol Chem
Title: Chronic inhibition of pyruvate dehydrogenase in heart triggers an adaptive metabolic response.
Volume: 286
Issue: 13
Pages: 11155-62
Publication
First Author: Morita M
Year: 2011
Journal: EMBO J
Title: Obesity resistance and increased hepatic expression of catabolism-related mRNAs in Cnot3+/- mice.
Volume: 30
Issue: 22
Pages: 4678-91
Publication
First Author: Gherardi G
Year: 2019
Journal: Cell Death Differ
Title: Loss of mitochondrial calcium uniporter rewires skeletal muscle metabolism and substrate preference.
Volume: 26
Issue: 2
Pages: 362-381
Publication
First Author: Wongsiriroj N
Year: 2014
Journal: J Lipid Res
Title: Genetic dissection of retinoid esterification and accumulation in the liver and adipose tissue.
Volume: 55
Issue: 1
Pages: 104-14