Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
277
![FASTA](model/images/fasta.gif) |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5556218 |
Assay Type: |
Northern blot |
Annotation Date: |
2014-04-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737323 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5556255 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Fgfr2 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gong SG |
Year: |
2012 |
Journal: |
Childs Nerv Syst |
Title: |
The Fgfr2 W290R mouse model of Crouzon syndrome. |
Volume: |
28 |
Issue: |
9 |
Pages: |
1495-503 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3639883 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-08-04 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1755022 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:3639929 |
Age: |
embryonic day 14.5 |
|
Note: |
Expression was detected in the inferior olivary nucleus (ION) as in wild type, but the ION area was increased in the mutant. |
Specimen Label: |
6P Fgfr2 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3639883 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-08-04 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1755022 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:3639929 |
Age: |
embryonic day 14.5 |
|
Note: |
Expression was detected in the inferior olivary nucleus. |
Specimen Label: |
6P Fgfr2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Warzecha CC |
Year: |
2009 |
Journal: |
Mol Cell |
Title: |
ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing. |
Volume: |
33 |
Issue: |
5 |
Pages: |
591-601 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mai S |
Year: |
2010 |
Journal: |
Dev Dyn |
Title: |
The missense mutation W290R in Fgfr2 causes developmental defects from aberrant IIIb and IIIc signaling. |
Volume: |
239 |
Issue: |
6 |
Pages: |
1888-900 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Y |
Year: |
2012 |
Journal: |
J Clin Invest |
Title: |
p38 Inhibition ameliorates skin and skull abnormalities in Fgfr2 Beare-Stevenson mice. |
Volume: |
122 |
Issue: |
6 |
Pages: |
2153-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Leng S |
Year: |
2020 |
Journal: |
Nat Commun |
Title: |
β-Catenin and FGFR2 regulate postnatal rosette-based adrenocortical morphogenesis. |
Volume: |
11 |
Issue: |
1 |
Pages: |
1680 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rigueur D |
Year: |
2019 |
Journal: |
Genesis |
Title: |
A requirement for Fgfr2 in middle ear development. |
Volume: |
57 |
Issue: |
1 |
Pages: |
e23252 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sims-Lucas S |
Year: |
2011 |
Journal: |
Development |
Title: |
Independent roles of Fgfr2 and Frs2alpha in ureteric epithelium. |
Volume: |
138 |
Issue: |
7 |
Pages: |
1275-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Aldridge K |
Year: |
2010 |
Journal: |
Dev Dyn |
Title: |
Brain phenotypes in two FGFR2 mouse models for Apert syndrome. |
Volume: |
239 |
Issue: |
3 |
Pages: |
987-97 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zingg D |
Year: |
2022 |
Journal: |
Nature |
Title: |
Truncated FGFR2 is a clinically actionable oncogene in multiple cancers. |
Volume: |
608 |
Issue: |
7923 |
Pages: |
609-617 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guasti L |
Year: |
2013 |
Journal: |
Mol Cell Endocrinol |
Title: |
FGF signalling through Fgfr2 isoform IIIb regulates adrenal cortex development. |
Volume: |
371 |
Issue: |
1-2 |
Pages: |
182-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hosokawa R |
Year: |
2009 |
Journal: |
J Exp Zool B Mol Dev Evol |
Title: |
Epithelial-specific requirement of FGFR2 signaling during tooth and palate development. |
Volume: |
312B |
Issue: |
4 |
Pages: |
343-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim S |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
FGFR2 promotes breast tumorigenicity through maintenance of breast tumor-initiating cells. |
Volume: |
8 |
Issue: |
1 |
Pages: |
e51671 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chan KM |
Year: |
2012 |
Journal: |
Dev Cell |
Title: |
MT1-MMP inactivates ADAM9 to regulate FGFR2 signaling and calvarial osteogenesis. |
Volume: |
22 |
Issue: |
6 |
Pages: |
1176-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gredler ML |
Year: |
2015 |
Journal: |
Development |
Title: |
Tissue-specific roles of Fgfr2 in development of the external genitalia. |
Volume: |
142 |
Issue: |
12 |
Pages: |
2203-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ikeda Y |
Year: |
2017 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Fgfr2 is integral for bladder mesenchyme patterning and function. |
Volume: |
312 |
Issue: |
4 |
Pages: |
F607-F618 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bagheri-Fam S |
Year: |
2015 |
Journal: |
Hum Mol Genet |
Title: |
FGFR2 mutation in 46,XY sex reversal with craniosynostosis. |
Volume: |
24 |
Issue: |
23 |
Pages: |
6699-710 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bagheri-Fam S |
Year: |
2008 |
Journal: |
Dev Biol |
Title: |
Loss of Fgfr2 leads to partial XY sex reversal. |
Volume: |
314 |
Issue: |
1 |
Pages: |
71-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bagheri-Fam S |
Year: |
2017 |
Journal: |
Endocrinology |
Title: |
Testis Determination Requires a Specific FGFR2 Isoform to Repress FOXL2. |
Volume: |
158 |
Issue: |
11 |
Pages: |
3832-3843 |
|
•
•
•
•
•
|
Publication |
First Author: |
Balasooriya GI |
Year: |
2017 |
Journal: |
Development |
Title: |
FGFR2 is required for airway basal cell self-renewal and terminal differentiation. |
Volume: |
144 |
Issue: |
9 |
Pages: |
1600-1606 |
|
•
•
•
•
•
|
Publication |
First Author: |
Arman E |
Year: |
1999 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Fgfr2 is required for limb outgrowth and lung-branching morphogenesis. |
Volume: |
96 |
Issue: |
21 |
Pages: |
11895-9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6386982 |
Assay Type: |
RNase protection |
Annotation Date: |
2020-01-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1783828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6386999 |
Age: |
postnatal adult |
Image: |
S2 |
|
Specimen Label: |
Fgfr2 flox/flox +CRE |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6386982 |
Assay Type: |
RNase protection |
Annotation Date: |
2020-01-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1783828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6386999 |
Age: |
postnatal adult |
Image: |
S2 |
|
Specimen Label: |
FgfR2 flox/+ +CRE |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6386982 |
Assay Type: |
RNase protection |
Annotation Date: |
2020-01-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1783828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6386999 |
Age: |
postnatal adult |
Image: |
S2 |
|
Specimen Label: |
FgfR2 +/+ +CRE |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6363656 |
Assay Type: |
RNA in situ |
Annotation Date: |
2019-10-16 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3522328 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6363685 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Fgfr2 lox/lox not shown |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6451697 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-08-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3286020 |
Pattern: |
Regionally restricted |
Stage: |
TS20 |
Assay Id: |
MGI:6451702 |
Age: |
embryonic day 12.5 |
|
Note: |
Expression on basal surface of distal airway epithelium. |
Specimen Label: |
S1 FGFR2 E12.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6451697 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-08-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3286620 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:6451702 |
Age: |
embryonic day 12.5 |
|
|
Specimen Label: |
S1 FGFR2 E12.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6451697 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-08-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3286021 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:6451702 |
Age: |
embryonic day 13.5 |
|
Note: |
Expression on basal surface of distal airway epithelium. |
Specimen Label: |
S1 FGFR2 E13.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6451697 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-08-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3286621 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:6451702 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
S1 FGFR2 E13.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Molotkov A |
Year: |
2017 |
Journal: |
Dev Cell |
Title: |
Distinct Requirements for FGFR1 and FGFR2 in Primitive Endoderm Development and Exit from Pluripotency. |
Volume: |
41 |
Issue: |
5 |
Pages: |
511-526.e4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Clark JF |
Year: |
2023 |
Journal: |
Biol Open |
Title: |
FRS2-independent GRB2 interaction with FGFR2 is not required for embryonic development. |
Volume: |
12 |
Issue: |
7 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Haffner-Krausz R |
Year: |
1999 |
Journal: |
Mech Dev |
Title: |
Expression of Fgfr2 in the early mouse embryo indicates its involvement in preimplantation development. |
Volume: |
85 |
Issue: |
1-2 |
Pages: |
167-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Coumoul X |
Year: |
2005 |
Journal: |
Nucleic Acids Res |
Title: |
Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interference. |
Volume: |
33 |
Issue: |
11 |
Pages: |
e102 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bird AD |
Year: |
2023 |
Journal: |
Endocrinology |
Title: |
Somatic FGFR2 is Required for Germ Cell Maintenance in the Mouse Ovary. |
Volume: |
164 |
Issue: |
5 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Eswarakumar VP |
Year: |
2002 |
Journal: |
Development |
Title: |
The IIIc alternative of Fgfr2 is a positive regulator of bone formation. |
Volume: |
129 |
Issue: |
16 |
Pages: |
3783-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Häfner R |
Year: |
2015 |
Journal: |
Mol Cell Endocrinol |
Title: |
Fgfr2 is required for the expansion of the early adrenocortical primordium. |
Volume: |
413 |
|
Pages: |
168-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schmahl J |
Year: |
2004 |
Journal: |
Development |
Title: |
Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination. |
Volume: |
131 |
Issue: |
15 |
Pages: |
3627-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Meuser M |
Year: |
2022 |
Journal: |
Development |
Title: |
FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. |
Volume: |
149 |
Issue: |
1 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Xu W |
Year: |
2017 |
Journal: |
J Bone Miner Res |
Title: |
Inducible Activation of FGFR2 in Adult Mice Promotes Bone Formation After Bone Marrow Ablation. |
Volume: |
32 |
Issue: |
11 |
Pages: |
2194-2206 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yokota M |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Therapeutic effect of nanogel-based delivery of soluble FGFR2 with S252W mutation on craniosynostosis. |
Volume: |
9 |
Issue: |
7 |
Pages: |
e101693 |
|
•
•
•
•
•
|
Publication |
First Author: |
Morita J |
Year: |
2014 |
Journal: |
Dev Dyn |
Title: |
Soluble form of FGFR2 with S252W partially prevents craniosynostosis of the apert mouse model. |
Volume: |
243 |
Issue: |
4 |
Pages: |
560-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suzuki H |
Year: |
2012 |
Journal: |
J Cell Physiol |
Title: |
Apert syndrome mutant FGFR2 and its soluble form reciprocally alter osteogenesis of primary calvarial osteoblasts. |
Volume: |
227 |
Issue: |
9 |
Pages: |
3267-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Motch Perrine SM |
Year: |
2014 |
Journal: |
BMC Dev Biol |
Title: |
Craniofacial divergence by distinct prenatal growth patterns in Fgfr2 mutant mice. |
Volume: |
14 |
|
Pages: |
8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yeh E |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Novel molecular pathways elicited by mutant FGFR2 may account for brain abnormalities in Apert syndrome. |
Volume: |
8 |
Issue: |
4 |
Pages: |
e60439 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dorry SJ |
Year: |
2020 |
Journal: |
Am J Respir Cell Mol Biol |
Title: |
FGFR2 Is Required for AEC2 Homeostasis and Survival after Bleomycin-induced Lung Injury. |
Volume: |
62 |
Issue: |
5 |
Pages: |
608-621 |
|
•
•
•
•
•
|
Publication |
First Author: |
Aure MH |
Year: |
2023 |
Journal: |
Nat Commun |
Title: |
FGFR2 is essential for salivary gland duct homeostasis and MAPK-dependent seromucous acinar cell differentiation. |
Volume: |
14 |
Issue: |
1 |
Pages: |
6485 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hains DS |
Year: |
2010 |
Journal: |
J Urol |
Title: |
High incidence of vesicoureteral reflux in mice with Fgfr2 deletion in kidney mesenchyma. |
Volume: |
183 |
Issue: |
5 |
Pages: |
2077-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Iseki S |
Year: |
1999 |
Journal: |
Development |
Title: |
Fgfr1 and Fgfr2 have distinct differentiation- and proliferation-related roles in the developing mouse skull vault. |
Volume: |
126 |
Issue: |
24 |
Pages: |
5611-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Siggers P |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
A novel mouse Fgfr2 mutant, hobbyhorse (hob), exhibits complete XY gonadal sex reversal. |
Volume: |
9 |
Issue: |
6 |
Pages: |
e100447 |
|
•
•
•
•
•
|
Publication |
First Author: |
Müller Smith K |
Year: |
2012 |
Journal: |
Brain Res |
Title: |
Impaired motor coordination and disrupted cerebellar architecture in Fgfr1 and Fgfr2 double knockout mice. |
Volume: |
1460 |
|
Pages: |
12-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gorivodsky M |
Year: |
2003 |
Journal: |
Development |
Title: |
Novel roles of Fgfr2 in AER differentiation and positioning of the dorsoventral limb interface. |
Volume: |
130 |
Issue: |
22 |
Pages: |
5471-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Blak AA |
Year: |
2007 |
Journal: |
Dev Biol |
Title: |
Fgfr2 and Fgfr3 are not required for patterning and maintenance of the midbrain and anterior hindbrain. |
Volume: |
303 |
Issue: |
1 |
Pages: |
231-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Candi E |
Year: |
2007 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
DeltaNp63 regulates thymic development through enhanced expression of FgfR2 and Jag2. |
Volume: |
104 |
Issue: |
29 |
Pages: |
11999-2004 |
|
•
•
•
•
•
|
Publication |
First Author: |
Deuper L |
Year: |
2022 |
Journal: |
Development |
Title: |
Mesenchymal FGFR1 and FGFR2 control patterning of the ureteric mesenchyme by balancing SHH and BMP4 signaling. |
Volume: |
149 |
Issue: |
17 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mukhopadhyay A |
Year: |
2013 |
Journal: |
Dev Biol |
Title: |
Negative regulation of Shh levels by Kras and Fgfr2 during hair follicle development. |
Volume: |
373 |
Issue: |
2 |
Pages: |
373-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wernlé KK |
Year: |
2023 |
Journal: |
Dev Dyn |
Title: |
Loss of Fgfr1 and Fgfr2 in Scleraxis-lineage cells leads to enlarged bone eminences and attachment cell death. |
Volume: |
252 |
Issue: |
9 |
Pages: |
1180-1188 |
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•
•
•
•
•
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Publication |
First Author: |
Iseki S |
Year: |
1997 |
Journal: |
Development |
Title: |
Fgfr2 and osteopontin domains in the developing skull vault are mutually exclusive and can be altered by locally applied FGF2. |
Volume: |
124 |
Issue: |
17 |
Pages: |
3375-84 |
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•
•
•
•
•
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Publication |
First Author: |
Kawane T |
Year: |
2018 |
Journal: |
Sci Rep |
Title: |
Runx2 is required for the proliferation of osteoblast progenitors and induces proliferation by regulating Fgfr2 and Fgfr3. |
Volume: |
8 |
Issue: |
1 |
Pages: |
13551 |
|
•
•
•
•
•
|
Publication |
First Author: |
Snyder-Warwick AK |
Year: |
2010 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Analysis of a gain-of-function FGFR2 Crouzon mutation provides evidence of loss of function activity in the etiology of cleft palate. |
Volume: |
107 |
Issue: |
6 |
Pages: |
2515-20 |
|
•
•
•
•
•
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Publication |
First Author: |
Stevens HE |
Year: |
2010 |
Journal: |
J Neurosci |
Title: |
Fgfr2 is required for the development of the medial prefrontal cortex and its connections with limbic circuits. |
Volume: |
30 |
Issue: |
16 |
Pages: |
5590-602 |
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•
•
•
•
•
|
Publication |
First Author: |
Heuzé Y |
Year: |
2014 |
Journal: |
Bone |
Title: |
Morphological comparison of the craniofacial phenotypes of mouse models expressing the Apert FGFR2 S252W mutation in neural crest- or mesoderm-derived tissues. |
Volume: |
63 |
|
Pages: |
101-9 |
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•
•
•
•
•
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Publication |
First Author: |
De Langhe SP |
Year: |
2006 |
Journal: |
Dev Biol |
Title: |
Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung. |
Volume: |
299 |
Issue: |
1 |
Pages: |
52-62 |
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•
•
•
•
•
|
Publication |
First Author: |
MartÃnez-AbadÃas N |
Year: |
2010 |
Journal: |
Dev Dyn |
Title: |
Beyond the closed suture in apert syndrome mouse models: evidence of primary effects of FGFR2 signaling on facial shape at birth. |
Volume: |
239 |
Issue: |
11 |
Pages: |
3058-71 |
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•
•
•
•
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Publication |
First Author: |
Lin Y |
Year: |
2009 |
Journal: |
Dev Dyn |
Title: |
FGFR2 in the dental epithelium is essential for development and maintenance of the maxillary cervical loop, a stem cell niche in mouse incisors. |
Volume: |
238 |
Issue: |
2 |
Pages: |
324-30 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6172900 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689419 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:6190277 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
Table S2 - E11.5 - Fgfr2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6172900 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:6190277 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Table S2 - E13.5 - Fgfr2 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6172900 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689424 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6190277 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Table S2 - E15.5 - Fgfr2 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6172900 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689426 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:6190277 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
Table S2 - E18.5 - Fgfr2 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6172900 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190277 |
Age: |
postnatal day 4 |
|
|
Specimen Label: |
Table S2 - P4 - Fgfr2 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6172900 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190277 |
Age: |
postnatal day 14 |
|
|
Specimen Label: |
Table S2 - P14 - Fgfr2 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6172900 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190277 |
Age: |
postnatal day 28 |
|
|
Specimen Label: |
Table S2 - P28 - Fgfr2 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6363656 |
Assay Type: |
RNA in situ |
Annotation Date: |
2019-10-16 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3522328 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6363685 |
Age: |
postnatal adult |
|
Note: |
Expression appeared normal compared to control. |
Specimen Label: |
En1 Cre/+ Fgfr2 lox/lox not shown |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ota S |
Year: |
2009 |
Journal: |
Hum Mol Genet |
Title: |
The role of senescence and prosurvival signaling in controlling the oncogenic activity of FGFR2 mutants associated with cancer and birth defects. |
Volume: |
18 |
Issue: |
14 |
Pages: |
2609-21 |
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•
•
•
•
•
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Publication |
First Author: |
Abler LL |
Year: |
2009 |
Journal: |
Dev Dyn |
Title: |
Conditional gene inactivation reveals roles for Fgf10 and Fgfr2 in establishing a normal pattern of epithelial branching in the mouse lung. |
Volume: |
238 |
Issue: |
8 |
Pages: |
1999-2013 |
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•
•
•
•
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Publication |
First Author: |
Goissis MD |
Year: |
2023 |
Journal: |
PLoS One |
Title: |
Influence of FGF4 and BMP4 on FGFR2 dynamics during the segregation of epiblast and primitive endoderm cells in the pre-implantation mouse embryo. |
Volume: |
18 |
Issue: |
7 |
Pages: |
e0279515 |
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•
•
•
•
•
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Publication |
First Author: |
Yang J |
Year: |
2015 |
Journal: |
Cell Cycle |
Title: |
Binding of FGF2 to FGFR2 in an autocrine mode in trophectoderm cells is indispensable for mouse blastocyst formation through PKC-p38 pathway. |
Volume: |
14 |
Issue: |
20 |
Pages: |
3318-30 |
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•
•
•
•
•
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Publication |
First Author: |
Sims-Lucas S |
Year: |
2011 |
Journal: |
Dev Dyn |
Title: |
Fgfr1 and the IIIc isoform of Fgfr2 play critical roles in the metanephric mesenchyme mediating early inductive events in kidney development. |
Volume: |
240 |
Issue: |
1 |
Pages: |
240-9 |
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•
•
•
•
•
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Publication |
First Author: |
Kuslak SL |
Year: |
2007 |
Journal: |
Development |
Title: |
The mouse seminal vesicle shape mutation is allelic with Fgfr2. |
Volume: |
134 |
Issue: |
3 |
Pages: |
557-65 |
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•
•
•
•
•
|
Publication |
First Author: |
Hibberd CE |
Year: |
2016 |
Journal: |
Am J Med Genet A |
Title: |
FGFR-associated craniosynostosis syndromes and gastrointestinal defects. |
Volume: |
170 |
Issue: |
12 |
Pages: |
3215-3221 |
|
•
•
•
•
•
|
Publication |
First Author: |
Molotkov A |
Year: |
2018 |
Journal: |
Dev Biol |
Title: |
Distinct mechanisms for PDGF and FGF signaling in primitive endoderm development. |
Volume: |
442 |
Issue: |
1 |
Pages: |
155-161 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kurowski A |
Year: |
2019 |
Journal: |
Dev Biol |
Title: |
FGFR1 regulates trophectoderm development and facilitates blastocyst implantation. |
Volume: |
446 |
Issue: |
1 |
Pages: |
94-101 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ray AT |
Year: |
2023 |
Journal: |
Development |
Title: |
FGF signaling regulates salivary gland branching morphogenesis by modulating cell adhesion. |
Volume: |
150 |
Issue: |
6 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Nguyen MB |
Year: |
2018 |
Journal: |
Nat Commun |
Title: |
FGF signalling controls the specification of hair placode-derived SOX9 positive progenitors to Merkel cells. |
Volume: |
9 |
Issue: |
1 |
Pages: |
2333 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ray AT |
Year: |
2020 |
Journal: |
Genes Dev |
Title: |
FGF signaling regulates development by processes beyond canonical pathways. |
Volume: |
34 |
Issue: |
23-24 |
Pages: |
1735-1752 |
|
•
•
•
•
•
|
Publication |
First Author: |
Aoyama E |
Year: |
2012 |
Journal: |
FEBS Lett |
Title: |
CCN2/CTGF binds to fibroblast growth factor receptor 2 and modulates its signaling. |
Volume: |
586 |
Issue: |
24 |
Pages: |
4270-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wilke TA |
Year: |
1997 |
Journal: |
Dev Dyn |
Title: |
Expression of fibroblast growth factor receptors (FGFR1, FGFR2, FGFR3) in the developing head and face. |
Volume: |
210 |
Issue: |
1 |
Pages: |
41-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Konishi M |
Year: |
2008 |
Journal: |
Mol Cell Endocrinol |
Title: |
Role of Fgf receptor 2c in adipocyte hypertrophy in mesenteric white adipose tissue. |
Volume: |
287 |
Issue: |
1-2 |
Pages: |
13-9 |
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•
•
•
•
|