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Search results 301 to 400 out of 432 for Msh2

0.039s
Type Details Score
Publication
First Author: Naigamwalla D
Year: 2000
Journal: Cancer Res
Title: Polyethylene glycol 8000 and colon carcinogenesis: inhibition in the F344 rat, promotion in the Min mouse.
Volume: 60
Issue: 24
Pages: 6856-8
Publication
First Author: Feng Y
Year: 2021
Journal: Nature
Title: FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturation.
Volume: 600
Issue: 7888
Pages: 324-328
Publication
First Author: Oda S
Year: 2005
Journal: Nucleic Acids Res
Title: Two modes of microsatellite instability in human cancer: differential connection of defective DNA mismatch repair to dinucleotide repeat instability.
Volume: 33
Issue: 5
Pages: 1628-36
Publication
First Author: Will B
Year: 2015
Journal: Nat Med
Title: Minimal PU.1 reduction induces a preleukemic state and promotes development of acute myeloid leukemia.
Volume: 21
Issue: 10
Pages: 1172-81
Publication
First Author: Cranston A
Year: 1999
Journal: Mamm Genome
Title: Female embryonic lethality in Msh2-Trp53 nullizygous mice is strain dependent.
Volume: 10
Issue: 10
Pages: 1020-2
Publication
First Author: Enoiu M
Year: 2012
Journal: Nucleic Acids Res
Title: Repair of cisplatin-induced DNA interstrand crosslinks by a replication-independent pathway involving transcription-coupled repair and translesion synthesis.
Volume: 40
Issue: 18
Pages: 8953-64
Publication
First Author: van Oers JM
Year: 2014
Journal: Oncogene
Title: The MutSĪ² complex is a modulator of p53-driven tumorigenesis through its functions in both DNA double-strand break repair and mismatch repair.
Volume: 33
Issue: 30
Pages: 3939-46
Publication  
First Author: Martinez-Usatorre A
Year: 2021
Journal: Sci Transl Med
Title: Overcoming microenvironmental resistance to PD-1 blockade in genetically engineered lung cancer models.
Volume: 13
Issue: 606
Publication
First Author: Boulianne B
Year: 2013
Journal: J Immunol
Title: AID and caspase 8 shape the germinal center response through apoptosis.
Volume: 191
Issue: 12
Pages: 5840-7
Publication
First Author: Campbell MR
Year: 2005
Journal: Cancer Res
Title: A lack of DNA mismatch repair on an athymic murine background predisposes to hematologic malignancy.
Volume: 65
Issue: 7
Pages: 2626-35
Publication
First Author: Schrader CE
Year: 1999
Journal: J Exp Med
Title: Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes.
Volume: 190
Issue: 3
Pages: 323-30
Publication
First Author: Owens JA
Year: 2021
Journal: Cell Mol Gastroenterol Hepatol
Title: Lactobacillus rhamnosus GG Orchestrates an Antitumor Immune Response.
Volume: 12
Issue: 4
Pages: 1311-1327
Publication
First Author: Albertson TM
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: DNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice.
Volume: 106
Issue: 40
Pages: 17101-4
Publication
First Author: Belcheva A
Year: 2014
Journal: Cell
Title: Gut microbial metabolism drives transformation of MSH2-deficient colon epithelial cells.
Volume: 158
Issue: 2
Pages: 288-299
Publication
First Author: Sansom OJ
Year: 2001
Journal: Cancer Res
Title: Suppression of intestinal and mammary neoplasia by lifetime administration of aspirin in Apc(Min/+) and Apc(Min/+), Msh2(-/-) mice.
Volume: 61
Issue: 19
Pages: 7060-4
Publication
First Author: Belcheva A
Year: 2013
Journal: PLoS One
Title: Elevated incidence of polyp formation in APC(Min/āŗ)Msh2ā»/ā» mice is independent of nitric oxide-induced DNA mutations.
Volume: 8
Issue: 5
Pages: e65204
Publication
First Author: Kucherlapati MH
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Loss of Rb1 in the gastrointestinal tract of Apc1638N mice promotes tumors of the cecum and proximal colon.
Volume: 105
Issue: 40
Pages: 15493-8
Publication
First Author: Bacher JW
Year: 2005
Journal: Mol Carcinog
Title: Use of mononucleotide repeat markers for detection of microsatellite instability in mouse tumors.
Volume: 44
Issue: 4
Pages: 285-92
Publication
First Author: Shenkar R
Year: 2015
Journal: Genet Med
Title: Exceptional aggressiveness of cerebral cavernous malformation disease associated with PDCD10 mutations.
Volume: 17
Issue: 3
Pages: 188-196
Publication
First Author: Jinnah HA
Year: 1993
Journal: J Neurochem
Title: Brain purines in a genetic mouse model of Lesch-Nyhan disease.
Volume: 60
Issue: 6
Pages: 2036-45
Publication
First Author: Zhao XN
Year: 2015
Journal: Hum Mutat
Title: The transcription-coupled repair protein ERCC6/CSB also protects against repeat expansion in a mouse model of the fragile X premutation.
Volume: 36
Issue: 4
Pages: 482-7
Publication
First Author: Hance KW
Year: 2005
Journal: Mutat Res
Title: Mouse models expressing human carcinoembryonic antigen (CEA) as a transgene: evaluation of CEA-based cancer vaccines.
Volume: 576
Issue: 1-2
Pages: 132-54
Publication
First Author: Boivin GP
Year: 2003
Journal: Gastroenterology
Title: Pathology of mouse models of intestinal cancer: consensus report and recommendations.
Volume: 124
Issue: 3
Pages: 762-77
Publication
First Author: Vuong BQ
Year: 2013
Journal: Nat Immunol
Title: A DNA break- and phosphorylation-dependent positive feedback loop promotes immunoglobulin class-switch recombination.
Volume: 14
Issue: 11
Pages: 1183-1189
Publication
First Author: Schrader CE
Year: 2007
Journal: J Immunol
Title: Activation-induced cytidine deaminase-dependent DNA breaks in class switch recombination occur during G1 phase of the cell cycle and depend upon mismatch repair.
Volume: 179
Issue: 9
Pages: 6064-71
Publication
First Author: Pastille E
Year: 2019
Journal: Mucosal Immunol
Title: The IL-33/ST2 pathway shapes the regulatory T cell phenotype to promote intestinal cancer.
Volume: 12
Issue: 4
Pages: 990-1003
Publication
First Author: Irrazabal T
Year: 2020
Journal: Nat Commun
Title: Limiting oxidative DNA damage reduces microbe-induced colitis-associated colorectal cancer.
Volume: 11
Issue: 1
Pages: 1802
Publication
First Author: Yoshioka K
Year: 2006
Journal: Mol Cell
Title: ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic O6-methylguanine adducts.
Volume: 22
Issue: 4
Pages: 501-10
Publication
First Author: Ghodgaonkar MM
Year: 2013
Journal: Mol Cell
Title: Ribonucleotides misincorporated into DNA act as strand-discrimination signals in eukaryotic mismatch repair.
Volume: 50
Issue: 3
Pages: 323-32
Publication
First Author: PeltomƤki P
Year: 2001
Journal: Mutat Res
Title: DNA mismatch repair and cancer.
Volume: 488
Issue: 1
Pages: 77-85
Publication
First Author: Schmutte C
Year: 1998
Journal: Cancer Res
Title: Refined chromosomal localization of the mismatch repair and hereditary nonpolyposis colorectal cancer genes hMSH2 and hMSH6.
Volume: 58
Issue: 22
Pages: 5023-6
Publication
First Author: Oliver G
Year: 1995
Journal: Development
Title: Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development.
Volume: 121
Issue: 12
Pages: 4045-55
Publication
First Author: Spehlmann ME
Year: 2013
Journal: J Immunol
Title: Trp53 deficiency protects against acute intestinal inflammation.
Volume: 191
Issue: 2
Pages: 837-47
Publication
First Author: Kolas NK
Year: 2005
Journal: J Cell Biol
Title: Localization of MMR proteins on meiotic chromosomes in mice indicates distinct functions during prophase I.
Volume: 171
Issue: 3
Pages: 447-58
Publication
First Author: Kneitz B
Year: 2000
Journal: Genes Dev
Title: MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice.
Volume: 14
Issue: 9
Pages: 1085-97
Publication
First Author: Jacobs H
Year: 1998
Journal: J Exp Med
Title: Hypermutation of immunoglobulin genes in memory B cells of DNA repair-deficient mice.
Volume: 187
Issue: 11
Pages: 1735-43
Publication
First Author: Keil KP
Year: 2013
Journal: Gene Expr Patterns
Title: Catalog of mRNA expression patterns for DNA methylating and demethylating genes in developing mouse lower urinary tract.
Volume: 13
Issue: 8
Pages: 413-24
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Koss M
Year: 2012
Journal: Dev Cell
Title: Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.
Volume: 22
Issue: 5
Pages: 913-26
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
UniProt Feature
Begin: 2
Description: DNA mismatch repair protein Msh2
Type: chain
End: 935
Protein
Organism: Mus musculus/domesticus
Length: 68  
Fragment?: true
Publication
First Author: Houlleberghs H
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Oligonucleotide-directed mutagenesis screen to identify pathogenic Lynch syndrome-associated MSH2 DNA mismatch repair gene variants.
Volume: 113
Issue: 15
Pages: 4128-33
Publication
First Author: Vani RG
Year: 1997
Journal: Gene
Title: Cloning of the cDNA encoding rat homologue of the mismatch repair gene MSH2 and its expression during spermatogenesis.
Volume: 185
Issue: 1
Pages: 19-26
Publication
First Author: Hirayama Y
Year: 1999
Journal: Exp Anim
Title: Linkage mapping of the rat Msh2 DNA mismatch repair gene on chromosome 6.
Volume: 48
Issue: 1
Pages: 63-4
Allele
Name: mutS homolog 2; targeted mutation 2, Hein Te Riele
Allele Type: Targeted
Attribute String: Not Specified
DO Term
Publication
First Author: Bhandari A
Year: 2013
Journal: Oncogene
Title: The Grainyhead transcription factor Grhl3/Get1 suppresses miR-21 expression and tumorigenesis in skin: modulation of the miR-21 target MSH2 by RNA-binding protein DND1.
Volume: 32
Issue: 12
Pages: 1497-507
DO Term
Gene
Type: gene
Organism: human
Allele
Name: mutS homolog 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
GO Term
GO Term
Protein Domain
Type: Family
Description: Mismatch repair (MMR) is one of five major DNA repair pathways, the others being homologous recombination repair, non-homologous end joining, nucleotide excision repair, and base excision repair. The mismatch repair system recognises and repairs mispaired or unpaired nucleotides that result from errors in DNA replication. The most extensively studied general MMR system is the MutHLS pathway of the bacterium Escherichia coli. In the first step of the MutHLS pathway, the MutS protein (in the form of a dimer) binds to the site of a mismatch in double-stranded DNA. Through a complex interaction between MutS, MutL and MutH, a section of the newly replicated DNA strand (and thus the strand with the replication error) at the location of the mismatch bound by MutS is targeted for removal []. Homologues of MutS have been found in many species including eukaryotes, Archaea and other bacteria, and together these proteins have been grouped into the MutS family.This entry represents a subset of the MutS family members, including Msh2. Msh2 (MutS homologue 2) has a dual role in DNA repair and apoptosis. Msh2 acts as a heterodimer with Msh6, which together function to recruit the Mlh (MutL homologue) - Pms (post-meiotic segregation) heterodimer, and to replace the mispaired base [].
Publication
First Author: Baker SM
Year: 1996
Journal: Nat Genet
Title: Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over.
Volume: 13
Issue: 3
Pages: 336-42
Publication
First Author: Drotschmann K
Year: 2002
Journal: Biol Chem
Title: DNA binding properties of the yeast Msh2-Msh6 and Mlh1-Pms1 heterodimers.
Volume: 383
Issue: 6
Pages: 969-75
Publication
First Author: Edelmann W
Year: 1996
Journal: Cell
Title: Meiotic pachytene arrest in MLH1-deficient mice.
Volume: 85
Issue: 7
Pages: 1125-34
Publication
First Author: Delbos F
Year: 2005
Journal: J Exp Med
Title: Contribution of DNA polymerase eta to immunoglobulin gene hypermutation in the mouse.
Volume: 201
Issue: 8
Pages: 1191-6
Publication
First Author: Ehrenstein MR
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Switch junction sequences in PMS2-deficient mice reveal a microhomology-mediated mechanism of Ig class switch recombination.
Volume: 98
Issue: 25
Pages: 14553-8
Publication
First Author: Krijger PH
Year: 2013
Journal: Eur J Immunol
Title: Rev1 is essential in generating G to C transversions downstream of the Ung2 pathway but not the Msh2+Ung2 hybrid pathway.
Volume: 43
Issue: 10
Pages: 2765-70
Publication
First Author: Liu S
Year: 2015
Journal: EMBO J
Title: Okazaki fragment maturation involves Ī±-segment error editing by the mammalian FEN1/MutSĪ± functional complex.
Volume: 34
Issue: 13
Pages: 1829-43
Publication
First Author: Phung QH
Year: 1999
Journal: J Immunol
Title: Hypermutation in Ig V genes from mice deficient in the MLH1 mismatch repair protein.
Volume: 162
Issue: 6
Pages: 3121-4
Publication
First Author: Horii A
Year: 1994
Journal: Biochem Biophys Res Commun
Title: Cloning, characterization and chromosomal assignment of the human genes homologous to yeast PMS1, a member of mismatch repair genes.
Volume: 204
Issue: 3
Pages: 1257-64
Publication
First Author: Prolla TA
Year: 1996
Journal: Semin Cancer Biol
Title: DNA mismatch repair deficient mice in cancer research.
Volume: 7
Issue: 5
Pages: 241-7
Publication
First Author: Sansom OJ
Year: 2004
Journal: Oncogene
Title: MBD4 deficiency does not increase mutation or accelerate tumorigenesis in mice lacking MMR.
Volume: 23
Issue: 33
Pages: 5693-6
Publication
First Author: MartĆ­n-LĆ³pez J
Year: 2018
Journal: Oncotarget
Title: Mutation of TGFĪ²-RII eliminates NSAID cancer chemoprevention.
Volume: 9
Issue: 16
Pages: 12554-12561
Publication
First Author: van den Broek WJ
Year: 2002
Journal: Hum Mol Genet
Title: Somatic expansion behaviour of the (CTG)n repeat in myotonic dystrophy knock-in mice is differentially affected by Msh3 and Msh6 mismatch-repair proteins.
Volume: 11
Issue: 2
Pages: 191-8
Publication
First Author: Foiry L
Year: 2006
Journal: Hum Genet
Title: Msh3 is a limiting factor in the formation of intergenerational CTG expansions in DM1 transgenic mice.
Volume: 119
Issue: 5
Pages: 520-6