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Search results 201 to 274 out of 274 for Dnm1

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Type Details Score
Publication
12456676 | J:81675
First Author: Modregger J
Year: 2003
Journal: J Biol Chem
Title: Characterization of Endophilin B1b, a brain-specific membrane-associated lysophosphatidic acid acyl transferase with properties distinct from endophilin A1.
Volume: 278
Issue: 6
Pages: 4160-7
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30692166 | J:272122
 
First Author: Milesi C
Year: 2019
Journal: Life Sci Alliance
Title: Redundant and nonredundant organismal functions of EPS15 and EPS15L1.
Volume: 2
Issue: 1
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8653788 | J:33098
First Author: Gautam M
Year: 1996
Journal: Cell
Title: Defective neuromuscular synaptogenesis in agrin-deficient mutant mice.
Volume: 85
Issue: 4
Pages: 525-35
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37042948 | J:340074
First Author: Wu J
Year: 2023
Journal: Blood Adv
Title: EHBP1L1, an apicobasal polarity regulator, is critical for nuclear polarization during enucleation of erythroblasts.
Volume: 7
Issue: 14
Pages: 3382-3394
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Publication
21307259 | J:169453
First Author: Piccoli G
Year: 2011
Journal: J Neurosci
Title: LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool.
Volume: 31
Issue: 6
Pages: 2225-37
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Publication
18364031 | J:133208
First Author: Hämmerle B
Year: 2008
Journal: Eur J Neurosci
Title: The spatio-temporal and subcellular expression of the candidate Down syndrome gene Mnb/Dyrk1A in the developing mouse brain suggests distinct sequential roles in neuronal development.
Volume: 27
Issue: 5
Pages: 1061-74
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26880306 | J:250166
 
First Author: Liu K
Year: 2016
Journal: Sci Rep
Title: Transferrin Receptor Controls AMPA Receptor Trafficking Efficiency and Synaptic Plasticity.
Volume: 6
Pages: 21019
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Publication
24448406 | J:207976
 
First Author: Li Q
Year: 2014
Journal: Elife
Title: The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation.
Volume: 3
Pages: e01201
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Publication
25073924 | J:269440
 
First Author: Morgan-Smith M
Year: 2014
Journal: Elife
Title: GSK-3 signaling in developing cortical neurons is essential for radial migration and dendritic orientation.
Volume: 3
Pages: e02663
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Publication
19666558 | J:151951
First Author: Chen H
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice.
Volume: 106
Issue: 33
Pages: 13838-43
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Publication
26884322 | J:259558
 
First Author: Bhattacharyya S
Year: 2016
Journal: Sci Rep
Title: Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development.
Volume: 6
Pages: 20727
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Publication
22802532 | J:185949
First Author: Licatalosi DD
Year: 2012
Journal: Genes Dev
Title: Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain.
Volume: 26
Issue: 14
Pages: 1626-42
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11172053 | J:67552
First Author: Jiang CH
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: The effects of aging on gene expression in the hypothalamus and cortex of mice.
Volume: 98
Issue: 4
Pages: 1930-4
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Publication
17634366 | J:145263
First Author: Werner HB
Year: 2007
Journal: J Neurosci
Title: Proteolipid protein is required for transport of sirtuin 2 into CNS myelin.
Volume: 27
Issue: 29
Pages: 7717-30
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
16272155 | -
First Author: Naylor K
Year: 2006
Journal: J Biol Chem
Title: Mdv1 interacts with assembled dnm1 to promote mitochondrial division.
Volume: 281
Issue: 4
Pages: 2177-83
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Allele
Dnm1<em1Mcou> | MGI:7537406
Name: dynamin 1; endonuclease-mediated mutation 1, Michael A Cousin
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
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DO Term
DOID:0070376 | developmental and epileptic encephalopathy 31B
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DO Term
DOID:0080437 | developmental and epileptic encephalopathy 31A
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Publication
11113136 | -
First Author: Liu HY
Year: 2001
Journal: J Biol Chem
Title: Characterization of CAF4 and CAF16 reveals a functional connection between the CCR4-NOT complex and a subset of SRB proteins of the RNA polymerase II holoenzyme.
Volume: 276
Issue: 10
Pages: 7541-8
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Publication
16835275 | -
First Author: Schauss AC
Year: 2006
Journal: J Cell Sci
Title: Fis1p and Caf4p, but not Mdv1p, determine the polar localization of Dnm1p clusters on the mitochondrial surface.
Volume: 119
Issue: Pt 15
Pages: 3098-106
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Protein Domain
IPR021653 | Caf4
Type: Family
Description: Caf4 is a WD40 repeats containing protein involved in mitochondrial fission. It displays physical interactions with CCR4-NOT complex []. It has a paralogue, Mdv1. Both Caf4 and Mdv1 act as adapter proteins, binding to Fis1 on the mitochondrial outer membrane and recruiting the dynamin-like GTPase Dnm1 to form mitochondrial fission complexes []. However, Fis1 and Caf4, but not Mdv1, determine the polar localization of Dnm1 clusters on the mitochondrial surface [].
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Publication
17998537 | -
First Author: Zhang Y
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Structural basis for recruitment of mitochondrial fission complexes by Fis1.
Volume: 104
Issue: 47
Pages: 18526-30
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Publication
17362197 | -
 
First Author: Hoppins S
Year: 2007
Journal: Annu Rev Biochem
Title: The machines that divide and fuse mitochondria.
Volume: 76
Pages: 751-80
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Publication
23300936 | -
First Author: Guo Q
Year: 2012
Journal: PLoS One
Title: The mitochondrial fission adaptors Caf4 and Mdv1 are not functionally equivalent.
Volume: 7
Issue: 12
Pages: e53523
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Protein Domain
IPR033745 | Fis1_cytosol
Type: Domain
Description: Fis1, along with Dnm1 and Mdv1, is an essential protein in mediating mitochondrial fission. Dnm1 and Fis1 are highly conserved, with a common mechanism in disparate species. In mutants of these proteins, mitochondrial fission is impaired, resulting in networks of undivided mitochondria. Fis1 appears to act via the recruitment of division complexes to the mitochondrial outer membrane. Dnm1 is recruited to mitochondria via interactions with the adaptor proteins Caf4 and Mdv1, which bind directly to Fis1 [, ].The Fis1 N terminus is cytosolic andtethered to the mitochondrial outer membrane via a C-terminal transmembrane domain. The cytosolic domain of Fis1 forms a six-helix bundle, in which the central four helices consist of two tandem tetratricopeptide repeat (TPR)-like motifs, known to mediate protein-protein interactions [, , , ].
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Publication
15809300 | -
First Author: Suzuki M
Year: 2005
Journal: J Biol Chem
Title: Novel structure of the N terminus in yeast Fis1 correlates with a specialized function in mitochondrial fission.
Volume: 280
Issue: 22
Pages: 21444-52
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Publication
14623186 | -
First Author: Suzuki M
Year: 2003
Journal: J Mol Biol
Title: The solution structure of human mitochondria fission protein Fis1 reveals a novel TPR-like helix bundle.
Volume: 334
Issue: 3
Pages: 445-58
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Publication
14705031 | -
First Author: Dohm JA
Year: 2004
Journal: Proteins
Title: Cytosolic domain of the human mitochondrial fission protein fis1 adopts a TPR fold.
Volume: 54
Issue: 1
Pages: 153-6
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Publication
16968746 | -
First Author: Kuravi K
Year: 2006
Journal: J Cell Sci
Title: Dynamin-related proteins Vps1p and Dnm1p control peroxisome abundance in Saccharomyces cerevisiae.
Volume: 119
Issue: Pt 19
Pages: 3994-4001
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Protein Domain
IPR016543 | Fis1
Type: Family
Description: Fis1 is an outer mitochondrial membrane protein that plays a role in mitochondrial membrane fission []. In Saccharomyces cerevisiae, it facilitates mitochondrial fission by forming protein complexes with Dnm1 and Mdv1 []. It contains tetratrico-peptide repeat (TPR)-like domain and a C-terminal transmembrane region [, ].
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Publication
16009724 | -
First Author: Griffin EE
Year: 2005
Journal: J Cell Biol
Title: The WD40 protein Caf4p is a component of the mitochondrial fission machinery and recruits Dnm1p to mitochondria.
Volume: 170
Issue: 2
Pages: 237-48
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Publication
18513378 | -
First Author: Nagotu S
Year: 2008
Journal: Traffic
Title: Peroxisome fission in Hansenula polymorpha requires Mdv1 and Fis1, two proteins also involved in mitochondrial fission.
Volume: 9
Issue: 9
Pages: 1471-84
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Protein Domain
IPR021061 | Mt_division_protein_1
Type: Family
Description: This entry represents mitochondrial division protein 1 (Mdv1), which is a component of the mitochondrial fission machinery in Saccharomyces cerevisiae. The protein is also involved in peroxisome proliferation []. Mdv1 along with Fis1 is also involved in controlling Dnm-1 dependent devision, a GTPase involved in the mediation of mitochondrial division. In this role, Mdv1 is the linker between Fis1 and Dnm1. Mdv1 plays a key role in the regulation of Dnm1 self-assembly [].Mdv1 has a partially redundant function to CAF4 in acting as an adapter protein, binding to FIS1 on the mitochondrial outer membrane and recruiting the dynamin-like GTPase DNM1 to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division [, ]. Mdv1 interacts with CAF4, DNM1 and FIS1, components of the mitochondrial fission machinery. It interacts via its N-terminal, coiled-coil extension (NTE) with FIS1, and via its WD repeats with DNM1. Mdv1 is uniformly distributed on the cytoplasmic face of the mitochondrial outer membrane. This localisation is dependent on FIS1. It reorganises to punctate structures on mitochondria, corresponding to mitochondrial constriction sites, at a late step in mitochondrial division. This relocalisation is dependent on DNM1.
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Publication
21149566 | J:167999
First Author: Koirala S
Year: 2010
Journal: J Cell Biol
Title: Molecular architecture of a dynamin adaptor: implications for assembly of mitochondrial fission complexes.
Volume: 191
Issue: 6
Pages: 1127-39
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Protein
Q9CQ92
Organism: Mus musculus/domesticus
Length: 152  
Fragment?: false
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Protein
D3YZ32
Organism: Mus musculus/domesticus
Length: 102  
Fragment?: false
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Protein
G3X9U9
Organism: Mus musculus/domesticus
Length: 145  
Fragment?: false
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Publication
11038183 | -
First Author: Mozdy AD
Year: 2000
Journal: J Cell Biol
Title: Dnm1p GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fis1p.
Volume: 151
Issue: 2
Pages: 367-80
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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