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Search results 201 to 224 out of 224 for Pak2

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0.018s

Type

Details

Score

UniProt Feature

Begin:	93
Description:	Phosphothreonine; by PAK2
Type:	modified residue
End:	93

•

UniProt Feature

Begin:	289
Description:	Phosphothreonine; by PAK2
Type:	modified residue
End:	289

•

UniProt Feature

Begin:	8
Description:	Phosphothreonine; by PAK2
Type:	modified residue
End:	8

•

UniProt Feature

Begin:	2
Description:	Phosphothreonine; by PAK2
Type:	modified residue
End:	2

•

UniProt Feature

Begin:	89
Description:	Phosphothreonine; by PAK2
Type:	modified residue
End:	89

•

UniProt Feature

Begin:	34
Description:	Phosphothreonine; by PAK2
Type:	modified residue
End:	34

•

UniProt Feature

Begin:	39
Description:	Phosphoserine; by PAK2
Type:	modified residue
End:	39

•

Allele

Pak2<em1Smoc> | MGI:7291521

Name:	p21 (RAC1) activated kinase 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type:	Endonuclease-mediated
Attribute String:	Null/knockout

•

UniProt Feature

Begin:	339
Description:	Phosphoserine; by PAK1, PAK2 and PAK3
Type:	modified residue
End:	339

•

UniProt Feature

Begin:	189
Description:	Phosphoserine; by PAK1, PAK2 and PAK3
Type:	modified residue
End:	189

•

UniProt Feature

Begin:	186
Description:	Phosphoserine; by PAK1, PAK2 and PAK3
Type:	modified residue
End:	186

•

Publication

18161990 | -

First Author:	Jung JH
Year:	2008
Journal:	Biochemistry
Title:	Phosphorylation of c-Abl by protein kinase Pak2 regulates differential binding of ABI2 and CRK.
Volume:	47
Issue:	3
Pages:	1094-104

•

Protein Domain

IPR035064 | STK_PAK2

Type:

Domain

Description:

PAK2 plays a role in pro-apoptotic signaling. It is cleaved and activated by caspases leading to morphological changes during apoptosis []. PAK2 is also activated in response to a variety of stresses including DNA damage, hyperosmolarity, serum starvation, and contact inhibition, and may play a role in coordinating the stress response []. PAK2 also contributes to cancer cell invasion through a mechanism distinct fromthat of PAK1 []. PAK2 belongs to the group I PAKs.Group I PAKs contain a PBD (p21-binding domain) overlapping with an AID (autoinhibitory domain), a C-terminal catalytic domain, SH3 binding sites and a non-classical SH3 binding site for PIX (PAK-interacting exchange factor). PAKs are Rho family GTPase-regulated kinases that serve as important mediators in the function of Cdc42 (cell division cycle 42) and Rac [].This entry corresponds to the PAK2 C-terminal catalytic domain.

•

Publication

30742951 | J:274324

First Author:	Ghatak S
Year:	2019
Journal:	Biochim Biophys Acta Gen Subj
Title:	Periostin/β1integrin interaction regulates p21-activated kinases in valvular interstitial cell survival and in actin cytoskeleton reorganization.
Volume:	1863
Issue:	5
Pages:	813-829

•

Publication

26659946 | J:239043

First Author:	Dubrac A
Year:	2016
Journal:	Circulation
Title:	Targeting NCK-Mediated Endothelial Cell Front-Rear Polarity Inhibits Neovascularization.
Volume:	133
Issue:	4
Pages:	409-21

•

Publication

12411320 | J:115524

First Author:	Pearce AC
Year:	2002
Journal:	Blood
Title:	Vav1, but not Vav2, contributes to platelet aggregation by CRP and thrombin, but neither is required for regulation of phospholipase C.
Volume:	100
Issue:	10
Pages:	3561-9

•

Publication

25379771 | J:225315

First Author:	Elsherif L
Year:	2014
Journal:	PLoS One
Title:	Potential compensation among group I PAK members in hindlimb ischemia and wound healing.
Volume:	9
Issue:	11
Pages:	e112239

•

Publication

10644687 | J:60205

First Author:	Cau J
Year:	2000
Journal:	J Biol Chem
Title:	Regulation of Xenopus p21-activated kinase (X-PAK2) by Cdc42 and maturation-promoting factor controls Xenopus oocyte maturation.
Volume:	275
Issue:	4
Pages:	2367-75

•

Publication

25560280 | J:220599

First Author:	Yun CY
Year:	2015
Journal:	J Invest Dermatol
Title:	p21-activated kinase 4 critically regulates melanogenesis via activation of the CREB/MITF and β-catenin/MITF pathways.
Volume:	135
Issue:	5
Pages:	1385-1394

•

Publication

36594092 | J:340148

First Author:	Yang S
Year:	2023
Journal:	Int J Biol Sci
Title:	Neutrophil Extracellular Traps Delay Diabetic Wound Healing by Inducing Endothelial-to-Mesenchymal Transition via the Hippo pathway.
Volume:	19
Issue:	1
Pages:	347-361

•

Publication

33432150 | J:322006

First Author:	Dufies O
Year:	2021
Journal:	Nat Microbiol
Title:	Escherichia coli Rho GTPase-activating toxin CNF1 mediates NLRP3 inflammasome activation via p21-activated kinases-1/2 during bacteraemia in mice.
Volume:	6
Issue:	3
Pages:	401-412

•

Publication

32468886 | J:304167

First Author:	Alfaidi M
Year:	2020
Journal:	J Am Heart Assoc
Title:	Nck1, But Not Nck2, Mediates Disturbed Flow-Induced p21-Activated Kinase Activation and Endothelial Permeability.
Volume:	9
Issue:	11
Pages:	e016099

•

Publication

17314161 | J:121098

First Author:	Priceputu E
Year:	2007
Journal:	J Virol
Title:	Primary human immunodeficiency virus type 1 nef alleles show major differences in pathogenicity in transgenic mice.
Volume:	81
Issue:	9
Pages:	4677-93

•

Publication

15489334 | -

First Author:	Gerhard DS
Year:	2004
Journal:	Genome Res
Title:	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume:	14
Issue:	10B
Pages:	2121-7

•

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