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Search results 1 to 100 out of 135 for Kdm6a

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Category: Publication
Type Details Score
Publication
First Author: Duplaquet L
Year: 2023
Journal: Nat Cell Biol
Title: KDM6A epigenetically regulates subtype plasticity in small cell lung cancer.
Volume: 25
Issue: 9
Pages: 1346-1358
Publication
First Author: Yoo KH
Year: 2016
Journal: Mol Cell Biol
Title: Histone Demethylase KDM6A Controls the Mammary Luminal Lineage through Enzyme-Independent Mechanisms.
Volume: 36
Issue: 16
Pages: 2108-20
Publication  
First Author: Itoh Y
Year: 2019
Journal: J Clin Invest
Title: The X-linked histone demethylase Kdm6a in CD4+ T lymphocytes modulates autoimmunity.
Volume: 130
Pages: 3852-3863
Publication
First Author: Tian L
Year: 2021
Journal: PLoS One
Title: Kdm6a deficiency restricted to mouse hematopoietic cells causes an age- and sex-dependent myelodysplastic syndrome-like phenotype.
Volume: 16
Issue: 11
Pages: e0255706
Publication
First Author: Kalisz M
Year: 2020
Journal: EMBO J
Title: HNF1A recruits KDM6A to activate differentiated acinar cell programs that suppress pancreatic cancer.
Volume: 39
Issue: 9
Pages: e102808
Publication
First Author: Andricovich J
Year: 2018
Journal: Cancer Cell
Title: Loss of KDM6A Activates Super-Enhancers to Induce Gender-Specific Squamous-like Pancreatic Cancer and Confers Sensitivity to BET Inhibitors.
Volume: 33
Issue: 3
Pages: 512-526.e8
Publication  
First Author: Yang L
Year: 2018
Journal: EMBO Rep
Title: KDM6A and KDM6B play contrasting roles in nuclear transfer embryos revealed by MERVL reporter system.
Volume: 19
Issue: 12
Publication
First Author: Kobatake K
Year: 2020
Journal: Clin Cancer Res
Title: Kdm6a Deficiency Activates Inflammatory Pathways, Promotes M2 Macrophage Polarization, and Causes Bladder Cancer in Cooperation with p53 Dysfunction.
Volume: 26
Issue: 8
Pages: 2065-2079
Publication
First Author: Umutoni D
Year: 2020
Journal: Genes Cells
Title: H3K27me3 demethylase UTX regulates the differentiation of a subset of bipolar cells in the mouse retina.
Volume: 25
Issue: 6
Pages: 402-412
Publication
First Author: Iwagawa T
Year: 2020
Journal: Invest Ophthalmol Vis Sci
Title: Jmjd3 Plays Pivotal Roles in the Proper Development of Early-Born Retinal Lineages: Amacrine, Horizontal, and Retinal Ganglion Cells.
Volume: 61
Issue: 11
Pages: 43
Publication
First Author: Gozdecka M
Year: 2018
Journal: Nat Genet
Title: UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs.
Volume: 50
Issue: 6
Pages: 883-894
Publication  
First Author: Huppertz S
Year: 2021
Journal: Exp Hematol
Title: KDM6A, a histone demethylase, regulates stress hematopoiesis and early B-cell differentiation.
Volume: 99
Pages: 32-43.e13
Publication    
First Author: Lesch BJ
Year: 2019
Journal: Elife
Title: Intergenerational epigenetic inheritance of cancer susceptibility in mammals.
Volume: 8
Publication
First Author: Cheng MI
Year: 2023
Journal: Nat Immunol
Title: The X-linked epigenetic regulator UTX controls NK cell-intrinsic sex differences.
Volume: 24
Issue: 5
Pages: 780-791
Publication
First Author: Wang AH
Year: 2013
Journal: EMBO J
Title: The histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesis.
Volume: 32
Issue: 8
Pages: 1075-86
Publication
First Author: Kaneko S
Year: 2018
Journal: Sci Adv
Title: X chromosome protects against bladder cancer in females via a KDM6A-dependent epigenetic mechanism.
Volume: 4
Issue: 6
Pages: eaar5598
Publication
First Author: Ma W
Year: 2022
Journal: Biol Sex Differ
Title: Sex-biased and parental allele-specific gene regulation by KDM6A.
Volume: 13
Issue: 1
Pages: 40
Publication  
First Author: Lin CL
Year: 2019
Journal: EMBO Mol Med
Title: A KDM6A-KLF10 reinforcing feedback mechanism aggravates diabetic podocyte dysfunction.
Volume: 11
Issue: 5
Publication
First Author: Berletch JB
Year: 2013
Journal: PLoS Genet
Title: Female bias in Rhox6 and 9 regulation by the histone demethylase KDM6A.
Volume: 9
Issue: 5
Pages: e1003489
Publication  
First Author: Wijayatunge R
Year: 2018
Journal: Mol Cell Neurosci
Title: The histone demethylase Kdm6b regulates a mature gene expression program in differentiating cerebellar granule neurons.
Volume: 87
Pages: 4-17
Publication
First Author: Hofstetter C
Year: 2016
Journal: J Cell Sci
Title: Inhibition of KDM6 activity during murine ESC differentiation induces DNA damage.
Volume: 129
Issue: 4
Pages: 788-803
Publication  
First Author: Gao Y
Year: 2022
Journal: Front Behav Neurosci
Title: Kdm6b Haploinsufficiency Causes ASD/ADHD-Like Behavioral Deficits in Mice.
Volume: 16
Pages: 905783
Publication
First Author: Mitchell JE
Year: 2021
Journal: Cell Rep
Title: UTX promotes CD8+ T cell-mediated antiviral defenses but reduces T cell durability.
Volume: 35
Issue: 2
Pages: 108966
Publication  
First Author: Li F
Year: 2022
Journal: Cells
Title: Adipocyte Utx Deficiency Promotes High-Fat Diet-Induced Metabolic Dysfunction in Mice.
Volume: 11
Issue: 2
Publication
First Author: Thieme S
Year: 2013
Journal: Blood
Title: The histone demethylase UTX regulates stem cell migration and hematopoiesis.
Volume: 121
Issue: 13
Pages: 2462-73
Publication
First Author: Mansour AA
Year: 2012
Journal: Nature
Title: The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming.
Volume: 488
Issue: 7411
Pages: 409-13
Publication
First Author: Welstead GG
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner.
Volume: 109
Issue: 32
Pages: 13004-9
Publication  
First Author: Huang Y
Year: 2022
Journal: Pharmacol Res
Title: Histone demethylase UTX aggravates acetaminophen overdose induced hepatotoxicity through dual mechanisms.
Volume: 175
Pages: 106021
Publication
First Author: Sera Y
Year: 2021
Journal: Blood
Title: UTX maintains the functional integrity of the murine hematopoietic system by globally regulating aging-associated genes.
Volume: 137
Issue: 7
Pages: 908-922
Publication  
First Author: Xia Y
Year: 2022
Journal: Biochem Biophys Res Commun
Title: Histone H3K27 demethylase, Utx, regulates osteoblast-to-osteocyte differentiation.
Volume: 590
Pages: 132-138
Publication
First Author: Ota K
Year: 2019
Journal: Sci Rep
Title: High Fat Diet Triggers a Reduction in Body Fat Mass in Female Mice Deficient for Utx demethylase.
Volume: 9
Issue: 1
Pages: 10036
Publication
First Author: Lian WS
Year: 2022
Journal: Cell Death Dis
Title: Histone H3K27 demethylase UTX compromises articular chondrocyte anabolism and aggravates osteoarthritic degeneration.
Volume: 13
Issue: 6
Pages: 538
Publication
First Author: Liu J
Year: 2012
Journal: Exp Hematol
Title: A functional role for the histone demethylase UTX in normal and malignant hematopoietic cells.
Volume: 40
Issue: 6
Pages: 487-98.e3
Publication
First Author: Beyaz S
Year: 2017
Journal: Nat Immunol
Title: The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells.
Volume: 18
Issue: 2
Pages: 184-195
Publication
First Author: Dhar SS
Year: 2016
Journal: Nucleic Acids Res
Title: An essential role for UTX in resolution and activation of bivalent promoters.
Volume: 44
Issue: 8
Pages: 3659-74
Publication
First Author: Inoue T
Year: 2021
Journal: J Immunol
Title: The Loss of H3K27 Histone Demethylase Utx in T Cells Aggravates Allergic Contact Dermatitis.
Volume: 207
Issue: 9
Pages: 2223-2234
Publication
First Author: Greenfield A
Year: 1996
Journal: Nat Genet
Title: An H-YDb epitope is encoded by a novel mouse Y chromosome gene.
Volume: 14
Issue: 4
Pages: 474-8
Publication  
First Author: Tang GB
Year: 2017
Journal: Front Mol Neurosci
Title: The Histone H3K27 Demethylase UTX Regulates Synaptic Plasticity and Cognitive Behaviors in Mice.
Volume: 10
Pages: 267
Publication
First Author: Li X
Year: 2018
Journal: Nat Commun
Title: UTX is an escape from X-inactivation tumor-suppressor in B cell lymphoma.
Volume: 9
Issue: 1
Pages: 2720
Publication
First Author: Greenfield A
Year: 1998
Journal: Hum Mol Genet
Title: The UTX gene escapes X inactivation in mice and humans.
Volume: 7
Issue: 4
Pages: 737-42
Publication
First Author: Suzuki J
Year: 2018
Journal: Nat Commun
Title: The tumor suppressor menin prevents effector CD8 T-cell dysfunction by targeting mTORC1-dependent metabolic activation.
Volume: 9
Issue: 1
Pages: 3296
Publication
First Author: Yamada T
Year: 2019
Journal: J Immunol
Title: Histone H3K27 Demethylase Negatively Controls the Memory Formation of Antigen-Stimulated CD8+ T Cells.
Volume: 202
Issue: 4
Pages: 1088-1098
Publication  
First Author: Manna S
Year: 2015
Journal: Nat Commun
Title: Histone H3 Lysine 27 demethylases Jmjd3 and Utx are required for T-cell differentiation.
Volume: 6
Pages: 8152
Publication
First Author: Shpargel KB
Year: 2014
Journal: PLoS Genet
Title: KDM6 demethylase independent loss of histone H3 lysine 27 trimethylation during early embryonic development.
Volume: 10
Issue: 8
Pages: e1004507
Publication
First Author: Faralli H
Year: 2016
Journal: J Clin Invest
Title: UTX demethylase activity is required for satellite cell-mediated muscle regeneration.
Volume: 126
Issue: 4
Pages: 1555-65
Publication
First Author: Rizq O
Year: 2023
Journal: Leukemia
Title: UTX inactivation in germinal center B cells promotes the development of multiple myeloma with extramedullary disease.
Volume: 37
Issue: 9
Pages: 1895-1907
Publication
First Author: Ntziachristos P
Year: 2014
Journal: Nature
Title: Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia.
Volume: 514
Issue: 7523
Pages: 513-7
Publication
First Author: Wu Q
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: In vivo CRISPR screening unveils histone demethylase UTX as an important epigenetic regulator in lung tumorigenesis.
Volume: 115
Issue: 17
Pages: E3978-E3986
Publication
First Author: Mallaney C
Year: 2019
Journal: Leukemia
Title: Kdm6b regulates context-dependent hematopoietic stem cell self-renewal and leukemogenesis.
Volume: 33
Issue: 10
Pages: 2506-2521
Publication
First Author: Seenundun S
Year: 2010
Journal: EMBO J
Title: UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis.
Volume: 29
Issue: 8
Pages: 1401-11
Publication
First Author: Wang SP
Year: 2017
Journal: Mol Cell
Title: A UTX-MLL4-p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription.
Volume: 67
Issue: 2
Pages: 308-321.e6
Publication    
First Author: Halstead AM
Year: 2017
Journal: Elife
Title: Bladder-cancer-associated mutations in RXRA activate peroxisome proliferator-activated receptors to drive urothelial proliferation.
Volume: 6
Publication
First Author: Li C
Year: 2017
Journal: Nat Commun
Title: Programmed cell senescence in skeleton during late puberty.
Volume: 8
Issue: 1
Pages: 1312
Publication
First Author: Zheng L
Year: 2018
Journal: Leukemia
Title: Utx loss causes myeloid transformation.
Volume: 32
Issue: 6
Pages: 1458-1465
Publication
First Author: Nakka K
Year: 2022
Journal: Science
Title: JMJD3 activated hyaluronan synthesis drives muscle regeneration in an inflammatory environment.
Volume: 377
Issue: 6606
Pages: 666-669
Publication  
First Author: Yi J
Year: 2021
Journal: Cancer Lett
Title: Histone demethylase UTX/KDM6A enhances tumor immune cell recruitment, promotes differentiation and suppresses medulloblastoma.
Volume: 499
Pages: 188-200
Publication
First Author: Kania AK
Year: 2022
Journal: J Immunol
Title: H3K27me3 Demethylase UTX Restrains Plasma Cell Formation.
Volume: 208
Issue: 8
Pages: 1873-1885
Publication
First Author: Cook KD
Year: 2015
Journal: Immunity
Title: T Follicular Helper Cell-Dependent Clearance of a Persistent Virus Infection Requires T Cell Expression of the Histone Demethylase UTX.
Volume: 43
Issue: 4
Pages: 703-14
Publication
First Author: Bai L
Year: 2019
Journal: Int J Biol Sci
Title: Histone Demethylase UTX is an Essential Factor for Zygotic Genome Activation and Regulates Zscan4 Expression in Mouse Embryos.
Volume: 15
Issue: 11
Pages: 2363-2372
Publication
First Author: Shpargel KB
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: UTX-guided neural crest function underlies craniofacial features of Kabuki syndrome.
Volume: 114
Issue: 43
Pages: E9046-E9055
Publication    
First Author: Luperchio TR
Year: 2021
Journal: Elife
Title: Leveraging the Mendelian disorders of the epigenetic machinery to systematically map functional epigenetic variation.
Volume: 10
Publication
First Author: Duong P
Year: 2021
Journal: J Biol Chem
Title: H3K27 demethylases are dispensable for activation of Polycomb-regulated injury response genes in peripheral nerve.
Volume: 297
Issue: 1
Pages: 100852
Publication
First Author: Miller SA
Year: 2010
Journal: Mol Cell
Title: Jmjd3 and UTX play a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression.
Volume: 40
Issue: 4
Pages: 594-605
Publication
First Author: Langille E
Year: 2022
Journal: Cancer Discov
Title: Loss of Epigenetic Regulation Disrupts Lineage Integrity, Induces Aberrant Alveogenesis, and Promotes Breast Cancer.
Volume: 12
Issue: 12
Pages: 2930-2953
Publication
First Author: Borensztein M
Year: 2017
Journal: Nat Commun
Title: Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass.
Volume: 8
Issue: 1
Pages: 1297
Publication
First Author: Li F
Year: 2021
Journal: Nat Commun
Title: Epigenetic interaction between UTX and DNMT1 regulates diet-induced myogenic remodeling in brown fat.
Volume: 12
Issue: 1
Pages: 6838
Publication
First Author: Wolstenholme JT
Year: 2013
Journal: Genes Brain Behav
Title: Sexual differentiation in the developing mouse brain: contributions of sex chromosome genes.
Volume: 12
Issue: 2
Pages: 166-80
Publication
First Author: Zhao J
Year: 2019
Journal: Int J Biol Sci
Title: p53 Mutant p53N236S Induces Neural Tube Defects in Female Embryos.
Volume: 15
Issue: 9
Pages: 2006-2015
Publication
First Author: Iida A
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Histone demethylase Jmjd3 is required for the development of subsets of retinal bipolar cells.
Volume: 111
Issue: 10
Pages: 3751-6
Publication
First Author: Shpargel KB
Year: 2012
Journal: PLoS Genet
Title: UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development.
Volume: 8
Issue: 9
Pages: e1002964
Publication
First Author: Wang C
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: UTX regulates mesoderm differentiation of embryonic stem cells independent of H3K27 demethylase activity.
Volume: 109
Issue: 38
Pages: 15324-9
Publication
First Author: Lei X
Year: 2018
Journal: Stem Cell Reports
Title: UTX Affects Neural Stem Cell Proliferation and Differentiation through PTEN Signaling.
Volume: 10
Issue: 4
Pages: 1193-1207
Publication
First Author: Koizumi M
Year: 2022
Journal: FASEB J
Title: UTX deficiency in neural stem/progenitor cells results in impaired neural development, fetal ventriculomegaly, and postnatal death.
Volume: 36
Issue: 12
Pages: e22662
Publication
First Author: Mann KM
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma.
Volume: 109
Issue: 16
Pages: 5934-41
Publication
First Author: Xu J
Year: 2002
Journal: Hum Mol Genet
Title: Sex differences in sex chromosome gene expression in mouse brain.
Volume: 11
Issue: 12
Pages: 1409-19
Publication
First Author: Cho YW
Year: 2007
Journal: J Biol Chem
Title: PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.
Volume: 282
Issue: 28
Pages: 20395-406
Publication  
First Author: Lee JE
Year: 2013
Journal: Elife
Title: H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation.
Volume: 2
Pages: e01503
Publication
First Author: Scoville DW
Year: 2015
Journal: Diabetes
Title: MLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet β-Cell Function.
Volume: 64
Issue: 11
Pages: 3772-83
Publication
First Author: Lee S
Year: 2012
Journal: Dev Cell
Title: UTX, a histone H3-lysine 27 demethylase, acts as a critical switch to activate the cardiac developmental program.
Volume: 22
Issue: 1
Pages: 25-37
Publication    
First Author: Guo T
Year: 2022
Journal: Elife
Title: KDM6B interacts with TFDP1 to activate P53 signaling in regulating mouse palatogenesis.
Volume: 11
Publication  
First Author: Shpargel KB
Year: 2020
Journal: Development
Title: The KMT2D Kabuki syndrome histone methylase controls neural crest cell differentiation and facial morphology.
Volume: 147
Issue: 21
Publication
First Author: Wang W
Year: 2022
Journal: Nat Commun
Title: The histone demethylase Kdm6b regulates subtype diversification of mouse spinal motor neurons during development.
Volume: 13
Issue: 1
Pages: 958
Publication
First Author: Kalantry S
Year: 2009
Journal: Nature
Title: Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation.
Volume: 460
Issue: 7255
Pages: 647-51
Publication
First Author: Dahl JA
Year: 2016
Journal: Nature
Title: Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.
Volume: 537
Issue: 7621
Pages: 548-552
Publication
First Author: Li Q
Year: 2014
Journal: PLoS Genet
Title: Stage-dependent and locus-specific role of histone demethylase Jumonji D3 (JMJD3) in the embryonic stages of lung development.
Volume: 10
Issue: 7
Pages: e1004524
Publication
First Author: Mugford JW
Year: 2012
Journal: Development
Title: Failure of extra-embryonic progenitor maintenance in the absence of dosage compensation.
Volume: 139
Issue: 12
Pages: 2130-8
Publication
First Author: Sessa A
Year: 2017
Journal: Cereb Cortex
Title: The Tbr2 Molecular Network Controls Cortical Neuronal Differentiation Through Complementary Genetic and Epigenetic Pathways.
Volume: 27
Issue: 6
Pages: 3378-3396
Publication
First Author: Blair HJ
Year: 2000
Journal: Mamm Genome
Title: Positioning of five genes (CASK, ARX, SAT, IMAGE cDNAs 248928 and 253949) from the human X chromosome short arm with respect to evolutionary breakpoints on the mouse X chromosome.
Volume: 11
Issue: 8
Pages: 710-2
Publication
First Author: Burton A
Year: 2013
Journal: Cell Rep
Title: Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo.
Volume: 5
Issue: 3
Pages: 687-701
Publication      
First Author: Cox BJ
Year: 2010
Journal: MGI Direct Data Submission
Title: Phenotypic annotation of the mouse X chromosome
Publication
First Author: Cox BJ
Year: 2010
Journal: Genome Res
Title: Phenotypic annotation of the mouse X chromosome.
Volume: 20
Issue: 8
Pages: 1154-64
Publication  
First Author: Zhang F
Year: 2021
Journal: Front Cell Dev Biol
Title: Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.
Volume: 9
Pages: 642931
Publication
First Author: Naruse C
Year: 2017
Journal: FASEB J
Title: New insights into the role of Jmjd3 and Utx in axial skeletal formation in mice.
Volume: 31
Issue: 6
Pages: 2252-2266
Publication
First Author: Allis CD
Year: 2007
Journal: Cell
Title: New nomenclature for chromatin-modifying enzymes.
Volume: 131
Issue: 4
Pages: 633-6
Publication
First Author: Narayanan R
Year: 2015
Journal: Cell Rep
Title: Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development.
Volume: 13
Issue: 9
Pages: 1842-54
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7