Type |
Details |
Score |
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
409
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
132
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
432
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Ataei Ataabadi E |
Year: |
2021 |
Journal: |
Oxid Med Cell Longev |
Title: |
Vascular Ageing Features Caused by Selective DNA Damage in Smooth Muscle Cell. |
Volume: |
2021 |
|
Pages: |
2308317 |
|
•
•
•
•
•
|
Allele |
Name: |
ocular degeneration with sex reversal; targeted mutation 1, Colin E Bishop |
Allele Type: |
Targeted |
|
|
•
•
•
•
•
|
Allele |
Name: |
hypoxanthine phosphoribosyltransferase 1; targeted mutation 3, Alan Peterson |
Allele Type: |
Targeted |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, Alan Peterson |
Allele Type: |
Targeted |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
hypoxanthine phosphoribosyltransferase 1; targeted mutation 2, Alan Peterson |
Allele Type: |
Targeted |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ods/Ods |
Background: |
either: 129S7/SvEvBrd or (involves: 129S7/SvEvBrd * FVB/N) |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Kirschner K |
Year: |
2007 |
Journal: |
DNA Repair (Amst) |
Title: |
Characterisation of Ercc1 deficiency in the liver and in conditional Ercc1-deficient primary hepatocytes in vitro. |
Volume: |
6 |
Issue: |
3 |
Pages: |
304-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jokić M |
Year: |
2016 |
Journal: |
Mol Cancer Res |
Title: |
Ercc1 Deficiency Promotes Tumorigenesis and Increases Cisplatin Sensitivity in a Tp53 Context-Specific Manner. |
Volume: |
14 |
Issue: |
11 |
Pages: |
1110-1123 |
|
•
•
•
•
•
|
Publication |
First Author: |
Borgesius NZ |
Year: |
2011 |
Journal: |
J Neurosci |
Title: |
Accelerated age-related cognitive decline and neurodegeneration, caused by deficient DNA repair. |
Volume: |
31 |
Issue: |
35 |
Pages: |
12543-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Qin Y |
Year: |
2004 |
Journal: |
Hum Mol Genet |
Title: |
Long-range activation of Sox9 in Odd Sex (Ods) mice. |
Volume: |
13 |
Issue: |
12 |
Pages: |
1213-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Doig J |
Year: |
2006 |
Journal: |
Oncogene |
Title: |
Mice with skin-specific DNA repair gene (Ercc1) inactivation are hypersensitive to ultraviolet irradiation-induced skin cancer and show more rapid actinic progression. |
Volume: |
25 |
Issue: |
47 |
Pages: |
6229-38 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lawrence NJ |
Year: |
2009 |
Journal: |
DNA Repair (Amst) |
Title: |
Topical thymidine dinucleotide application protects against UVB-induced skin cancer in mice with DNA repair gene (Ercc1)-deficient skin. |
Volume: |
8 |
Issue: |
5 |
Pages: |
664-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
de Graaf EL |
Year: |
2013 |
Journal: |
Mol Cell Proteomics |
Title: |
Spatio-temporal analysis of molecular determinants of neuronal degeneration in the aging mouse cerebellum. |
Volume: |
12 |
Issue: |
5 |
Pages: |
1350-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang X |
Year: |
2021 |
Journal: |
Glia |
Title: |
Intrinsic DNA damage repair deficiency results in progressive microglia loss and replacement. |
Volume: |
69 |
Issue: |
3 |
Pages: |
729-745 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ercc1/Ercc1 Hr /Hr Tg(KRT5-cre)5132Jlj/? |
Background: |
involves: 129P2/OlaHsd * C57BL/6J * DBA/2J * MF1 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Champagne DP |
Year: |
2014 |
Journal: |
Mutat Res |
Title: |
Illegitimate V(D)J recombination-mediated deletions in Notch1 and Bcl11b are not sufficient for extensive clonal expansion and show minimal age or sex bias in frequency or junctional processing. |
Volume: |
761 |
|
Pages: |
34-48 |
|
•
•
•
•
•
|
Publication |
First Author: |
Selfridge J |
Year: |
2010 |
Journal: |
DNA Repair (Amst) |
Title: |
Mice with DNA repair gene Ercc1 deficiency in a neural crest lineage are a model for late-onset Hirschsprung disease. |
Volume: |
9 |
Issue: |
6 |
Pages: |
653-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lawrence NJ |
Year: |
2008 |
Journal: |
DNA Repair (Amst) |
Title: |
A neurological phenotype in mice with DNA repair gene Ercc1 deficiency. |
Volume: |
7 |
Issue: |
2 |
Pages: |
281-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Van't Sant LJ |
Year: |
2021 |
Journal: |
Acta Neuropathol Commun |
Title: |
In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration. |
Volume: |
9 |
Issue: |
1 |
Pages: |
94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Raj DD |
Year: |
2014 |
Journal: |
Neurobiol Aging |
Title: |
Priming of microglia in a DNA-repair deficient model of accelerated aging. |
Volume: |
35 |
Issue: |
9 |
Pages: |
2147-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Birkisdóttir MB |
Year: |
2022 |
Journal: |
Front Aging Neurosci |
Title: |
Purkinje-cell-specific DNA repair-deficient mice reveal that dietary restriction protects neurons by cell-intrinsic preservation of genomic health. |
Volume: |
14 |
|
Pages: |
1095801 |
|
•
•
•
•
•
|