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Search results 1 to 100 out of 106 for Dph2

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0.058s
Type Details Score
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression  
Probe: MGI:1700852
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824380
Age: embryonic day 14.5
Image: euxassay_001242_01
Specimen Label: euxassay_001242_01
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1700852
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824380
Age: embryonic day 14.5
Image: euxassay_001242_02
Specimen Label: euxassay_001242_02
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:1700852
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824380
Age: embryonic day 14.5
Image: euxassay_001242_03
Specimen Label: euxassay_001242_03
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:1700852
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824380
Age: embryonic day 14.5
Image: euxassay_001242_04
Specimen Label: euxassay_001242_04
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:1700852
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824380
Age: embryonic day 14.5
Image: euxassay_001242_05
Specimen Label: euxassay_001242_05
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:1700852
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824380
Age: embryonic day 14.5
Image: euxassay_001242_06
Specimen Label: euxassay_001242_06
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:1700852
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824380
Age: embryonic day 14.5
Image: euxassay_001242_07
Specimen Label: euxassay_001242_07
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:1700852
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824380
Age: embryonic day 14.5
Image: euxassay_001242_08
Specimen Label: euxassay_001242_08
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:1700852
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824380
Age: embryonic day 14.5
Image: euxassay_001242_09
Specimen Label: euxassay_001242_09
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:1700852
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824380
Age: embryonic day 14.5
Image: euxassay_001242_17
Specimen Label: euxassay_001242_17
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:1700852
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1830623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824380
Age: embryonic day 14.5
Image: euxassay_001242_18
Specimen Label: euxassay_001242_18
Detected: true
Specimen Num: 11
Publication
First Author: Liu S
Year: 2004
Journal: Mol Cell Biol
Title: Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2.
Volume: 24
Issue: 21
Pages: 9487-97
Publication      
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniPathway vocabulary mapping
Publication
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Allele    
Name: DPH2 homolog; wild type
Allele
Name: DPH2 homolog; targeted mutation 1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Publication
First Author: Mattheakis LC
Year: 1993
Journal: Gene
Title: Diphthamide synthesis in Saccharomyces cerevisiae: structure of the DPH2 gene.
Volume: 132
Issue: 1
Pages: 149-54
Protein
Organism: Mus musculus/domesticus
Length: 489  
Fragment?: false
Allele
Name: DPH2 homolog; targeted mutation 2, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: DPH2 homolog; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Strain
Attribute String: mutant strain, coisogenic, targeted mutation
Strain
Attribute String: targeted mutation, mutant strain, coisogenic
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Allele  
Name: DPH2 homolog; gene trap IST13756E3, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Genotype
Symbol: Dph2/Dph2
Background: C57BL/6N-A Dph2/WtsiH
Zygosity: hm
Has Mutant Allele: true
DO Term
Strain
Attribute String: coisogenic, targeted mutation
Genotype
Symbol: Dph2/Dph2<+>
Background: C57BL/6N-A Dph2/WtsiH
Zygosity: ht
Has Mutant Allele: true
Protein Domain
Type: Family
Description: Archaeal and eukaryotic translation elongation factor 2 contain a unique posttranslationally modified histidine residue called diphthamide, the target of the diphtheria toxin []. This family represents Dph2 from Archaea. This iron-sulphur cluster enzyme is involved in the first step of diphthamide biosynthesis [].
Publication
First Author: Chen CM
Year: 2005
Journal: Curr Opin Genet Dev
Title: OVCA1: tumor suppressor gene.
Volume: 15
Issue: 1
Pages: 49-54
Publication
First Author: Dong M
Year: 2019
Journal: J Biol Inorg Chem
Title: The asymmetric function of Dph1-Dph2 heterodimer in diphthamide biosynthesis.
Volume: 24
Issue: 6
Pages: 777-782
Protein Domain
Type: Family
Description: Archaeal and eukaryotic translation elongation factor 2 contain a unique posttranslationally modified histidine residue called diphthamide, the target of the diphtheria toxin. Diphtheria toxin inhibits eukaryotic protein synthesis by ADP-ribosylating diphthamide in EF2 [].Members of this family include 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1/2 (also known as Diphtheria toxin resistance protein 1/2, DPH 1/2), which are involved in the first step of diphthamide synthesis [, ]. Archaeal DPHs are more similar to eukaryotic DPH1 than to DPH2 [].
Publication
First Author: Chen CM
Year: 2004
Journal: Genes Dev
Title: Ovca1 regulates cell proliferation, embryonic development, and tumorigenesis.
Volume: 18
Issue: 3
Pages: 320-32
Protein Domain
Type: Family
Description: This entry includes diphthamide synthesis DPH1 from eukaryotes and archaea and DPH2 from archaea.Archaeal and eukaryotic translation elongation factor 2 (EF-2) contain a unique posttranslationally modified histidine residue called diphthamide, which become the target for ADP-ribosylation by diphtheria toxin []. DPH1 catalyzes the first step of diphthamide biosynthesis and is required for the modification of EF-2 []. The human DPH1 is also known as OVCA1 (for ovarian cancer gene 1), a tumour suppressor gene that plays a crucial role in the regulation of cell proliferation, embryonic development, and tumorigenesis [].
Publication
First Author: Webb TR
Year: 2008
Journal: J Cell Sci
Title: Diphthamide modification of eEF2 requires a J-domain protein and is essential for normal development.
Volume: 121
Issue: Pt 19
Pages: 3140-5