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Search results 201 to 300 out of 475 for Dot1l

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Type Details Score
Publication
20427473 | J:160934
First Author: Reisenauer MR
Year: 2010
Journal: Am J Physiol Renal Physiol
Title: Dot1a contains three nuclear localization signals and regulates the epithelial Na+ channel (ENaC) at multiple levels.
Volume: 299
Issue: 1
Pages: F63-76
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Publication
28981838 | J:243553
First Author: Fisher CL
Year: 2017
Journal: Nucleic Acids Res
Title: An efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers.
Volume: 45
Issue: 21
Pages: e174
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Publication
32553114 | J:292114
   
First Author: Pereira M
Year: 2020
Journal: Elife
Title: A trans-eQTL network regulates osteoclast multinucleation and bone mass.
Volume: 9
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Publication
31748268 | J:282322
First Author: Ko HR
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Roles of ErbB3-binding protein 1 (EBP1) in embryonic development and gene-silencing control.
Volume: 116
Issue: 49
Pages: 24852-24860
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Publication
24105743 | J:202816
First Author: Wajapeyee N
Year: 2013
Journal: Genes Dev
Title: Oncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressors.
Volume: 27
Issue: 20
Pages: 2221-6
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Publication
34368113 | J:313616
 
First Author: Zhang F
Year: 2021
Journal: Front Cell Dev Biol
Title: Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.
Volume: 9
Pages: 642931
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Publication
18022353 | J:126799
First Author: Allis CD
Year: 2007
Journal: Cell
Title: New nomenclature for chromatin-modifying enzymes.
Volume: 131
Issue: 4
Pages: 633-6
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:175295
     
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Allele
Dot1l<Gt(RRR032)Byg> | MGI:3784999
Name: DOT1 like histone lysine methyltransferase; gene trap RRR032, BayGenomics
Allele Type: Gene trapped
Attribute String: Null/knockout, Reporter
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HT Experiment
GSE221994 | DOT1L deletion impairs the development of cortical Parvalbumin-expressing interneurons
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Gene
361285 | Mllt10
Type: gene
Organism: rat
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Gene
487096 | MLLT10
Type: gene
Organism: dog, domestic
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Gene
450343 | MLLT10
Type: gene
Organism: chimpanzee
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Gene
519864 | MLLT10
Type: gene
Organism: cattle
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Gene
492342 | mllt10
Type: gene
Organism: zebrafish
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Gene
100036598 | mllt10
Type: gene
Organism: frog, western clawed
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Gene
108719864 | mllt10.S
Type: gene
Organism: frog, African clawed
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Gene
494767 | mllt10.L
Type: gene
Organism: frog, African clawed
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Publication
34037658 | J:307937
 
First Author: Leon KE
Year: 2021
Journal: J Cell Biol
Title: DOT1L modulates the senescence-associated secretory phenotype through epigenetic regulation of IL1A.
Volume: 220
Issue: 8
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HT Experiment
GSE217931 | DOT1L promotes spermatid differentiation by regulating expression of genes required for histone-to-protamine replacement
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE95832 | Assesment of DOT1L direct targets via RNAseq at E14.5 of mouse cortex
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE142188 | Transcriptome of murine lumbar spinal cord at E12.5 in control and DOT1L cKO through Wnt1cre2 (B6.Cg-E2f1Tg(Wnt1-cre)2Sor/J, Jackson Laboratory #022501)
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Dot1l<em1Smoc> | MGI:7289387
Name: DOT1 like histone lysine methyltransferase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Interaction Experiment
Whitcomb SJ (2012)
Description: Histone Monoubiquitylation Position Determines Specificity and Direction of Enzymatic Crosstalk with Histone Methyltransferases Dot1L and PRC2.
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Interaction Experiment
Castano Betancourt MC (2012)
Description: Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis.
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Strain
MGI:6770705 | C57BL/6-Dot1l<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
22619169 | -
First Author: Whitcomb SJ
Year: 2012
Journal: J Biol Chem
Title: Histone monoubiquitylation position determines specificity and direction of enzymatic cross-talk with histone methyltransferases Dot1L and PRC2.
Volume: 287
Issue: 28
Pages: 23718-25
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Allele
Dot1l<tm1.1Tche> | MGI:4459468
Name: DOT1 like histone lysine methyltransferase; targeted mutation 1.1, Taiping Chen
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
22566624 | -
First Author: Castaño Betancourt MC
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis.
Volume: 109
Issue: 21
Pages: 8218-23
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Genotype
Genotype
Symbol: Dot1l/Dot1l
Background: either: (involves: C57BL/6) or (involves: 129/Sv * C57BL/6)
Zygosity: hm
Has Mutant Allele: true
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HT Experiment
GSE95833 | Assesment of Foxg1 targets via RNAseq at E13.5 of mouse cortex
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE184191 | Genome-wide mRNA expression analyses revealed dysregulation of genes important for cardiomyocyte function in XMlc2-Cre;Dot1L mutants and controls
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
E-GEOD-40090 | Mouse whole kidney, Dot1lAC vs. Dot1lf/f mice
Series Id: GSE40090
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Genotype
Genotype
Symbol: Dot1l/Dot1l Tg(Myhca-cre)1Abel/?
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
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Publication
32398749 | J:292157
First Author: Itskovich SS
Year: 2020
Journal: Nat Commun
Title: MBNL1 regulates essential alternative RNA splicing patterns in MLL-rearranged leukemia.
Volume: 11
Issue: 1
Pages: 2369
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Publication
30356100 | J:267817
First Author: Liu Y
Year: 2018
Journal: Nat Commun
Title: Nuclear lactate dehydrogenase A senses ROS to produce α-hydroxybutyrate for HPV-induced cervical tumor growth.
Volume: 9
Issue: 1
Pages: 4429
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Publication
18977325 | J:140628
First Author: Krivtsov AV
Year: 2008
Journal: Cancer Cell
Title: H3K79 methylation profiles define murine and human MLL-AF4 leukemias.
Volume: 14
Issue: 5
Pages: 355-68
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Publication
26214134 | J:227286
First Author: Soria-Valles C
Year: 2015
Journal: Nat Cell Biol
Title: NF-κB activation impairs somatic cell reprogramming in ageing.
Volume: 17
Issue: 8
Pages: 1004-13
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Publication
29777171 | J:263721
First Author: Skucha A
Year: 2018
Journal: Nat Commun
Title: MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity.
Volume: 9
Issue: 1
Pages: 1983
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Publication
31433981 | J:288447
First Author: Kara N
Year: 2019
Journal: Cell Rep
Title: The miR-216a-Dot1l Regulatory Axis Is Necessary and Sufficient for Müller Glia Reprogramming during Retina Regeneration.
Volume: 28
Issue: 8
Pages: 2037-2047.e4
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Publication
28931923 | J:256374
First Author: Ogoh H
Year: 2017
Journal: Sci Rep
Title: Mllt10 knockout mouse model reveals critical role of Af10-dependent H3K79 methylation in midfacial development.
Volume: 7
Issue: 1
Pages: 11922
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Protein Coding Gene
MGI:1329038 | Mllt10
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0023204 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0025373 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0025351 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0025319 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0025346 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0025106 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1329038 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0025789 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0024570 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0025085 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0025217 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0025180 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0025304 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0025211 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0025847 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0024319 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0024640 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024660 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0024119 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:3815898
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:3816702
Age: postnatal
Specimen Label: Metaphase II
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3815898
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3816702
Age: embryonic day 1.5
Specimen Label: 2-cell embryo
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3815898
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:3816702
Age: embryonic day 2.0
Specimen Label: 4-cell embryo
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3815898
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3816702
Age: embryonic day 2.5
Specimen Label: 8-cell embryo
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3815898
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:3816702
Age: embryonic day 3.0
Specimen Label: Morula
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:3815898
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3816702
Age: embryonic day 3.5
Specimen Label: E3.5 blastocyst
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:3815898
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360465
Stage: TS05
Assay Id: MGI:3816702
Age: embryonic day 4.5
Specimen Label: E4.5 blastocyst
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:3815898
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Stage: TS05
Assay Id: MGI:3816702
Age: embryonic day 4.5
Specimen Label: E4.5 inner cell mass
Detected: true
Specimen Num: 8
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