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Search results 201 to 234 out of 234 for Fermt1

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Type Details Score
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Allele
Fermt1<em1Smoc> | MGI:7289669
Name: fermitin family member 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
28595995 | J:244978
First Author: Hermann H
Year: 2017
Journal: J Invest Dermatol
Title: miR-146b Probably Assists miRNA-146a in the Suppression of Keratinocyte Proliferation and Inflammatory Responses in Psoriasis.
Volume: 137
Issue: 9
Pages: 1945-1954
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Publication
12697302 | -
First Author: Weinstein EJ
Year: 2003
Journal: Biochim Biophys Acta
Title: URP1: a member of a novel family of PH and FERM domain-containing membrane-associated proteins is significantly over-expressed in lung and colon carcinomas.
Volume: 1637
Issue: 3
Pages: 207-16
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Publication
22030399 | -
First Author: Liu J
Year: 2011
Journal: J Biol Chem
Title: Structural basis of phosphoinositide binding to kindlin-2 protein pleckstrin homology domain in regulating integrin activation.
Volume: 286
Issue: 50
Pages: 43334-42
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Publication
25173804 | -
 
First Author: Rozario T
Year: 2014
Journal: Mech Dev
Title: Diverse functions of kindlin/fermitin proteins during embryonic development in Xenopus laevis.
Volume: 133
Pages: 203-17
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Publication
21761481 | -
First Author: Canning CA
Year: 2011
Journal: Dev Dyn
Title: Developmental expression of the fermitin/kindlin gene family in Xenopus laevis embryos.
Volume: 240
Issue: 8
Pages: 1958-63
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Publication
24477625 | -
First Author: Ye F
Year: 2014
Journal: Front Med
Title: Talin and kindlin: the one-two punch in integrin activation.
Volume: 8
Issue: 1
Pages: 6-16
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Protein
A0A494BBJ8
Organism: Mus musculus/domesticus
Length: 266  
Fragment?: false
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Protein
A0A494B9F7
Organism: Mus musculus/domesticus
Length: 93  
Fragment?: true
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Protein
A0A2I3BPQ7
Organism: Mus musculus/domesticus
Length: 72  
Fragment?: true
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Protein
A6X940
Organism: Mus musculus/domesticus
Length: 258  
Fragment?: true
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Protein Domain
IPR037837 | PH_Kindlin/fermitin
Type: Domain
Description: Fermitin, also known as Unc-112-related protein [], functions as a mediator of integrin inside-out signalling. The recruitment of Fermitin proteins and Talin to the membrane mediates the terminal event of integrin signalling, via interaction with integrin beta subunits []. Fermatin has a FERM domain interrupted with a pleckstrin homology (PH) domain []. Fermitin family homologues (Fermt1, 2, and 3, also known as Kindlins) are each encoded by a different gene. In mammalian studies, Fermt1 is generally expressed in epithelial cells, Fermt2 is expressed in muscle tissues, and Fermt3 is expressed in hematopoietic lineages. Specifically Fermt2 is expressed in smooth and striated muscle tissues in mice and in the somites (a trunk muscle precursor) and neural crest in Xenopus embryos. As such it has been proposed that Fermt2 plays a role in cardiomyocyte and neural crest differentiation. Expression of mammalian Fermt3 is associated with hematopoietic lineages: the anterior ventral blood islands, vitelline veins, and early myeloid cells. In Xenopus embryos this expression, also include the notochord and cement gland [, ].This entry represents the PH domain of fermitins.
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Protein Domain
IPR037843 | Kindlin/fermitin
Type: Family
Description: Fermitin, also known as Unc-112-related protein [], functions as a mediator of integrin inside-out signalling. The recruitment of Fermitin proteins and Talin to the membrane mediates the terminal event of integrin signalling, via interaction with integrin beta subunits []. Fermatin has a FERM domain interrupted with a pleckstrin homology (PH) domain []. Fermitin family homologues (Fermt1, 2, and 3, also known as Kindlins) are each encoded by a different gene. In mammalian studies, Fermt1 is generally expressed in epithelial cells, Fermt2 is expressed in muscle tissues, and Fermt3 is expressed in hematopoietic lineages. Specifically Fermt2 is expressed in smooth and striated muscle tissues in mice and in the somites (a trunk muscle precursor) and neural crest in Xenopus embryos. As such it has been proposed that Fermt2 plays a role in cardiomyocyte and neural crest differentiation. Expression of mammalian Fermt3 is associated with hematopoietic lineages: the anterior ventral blood islands, vitelline veins, and early myeloid cells. In Xenopus embryos this expression, also include the notochord and cement gland [, ].
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Protein
Q8K1B8
Organism: Mus musculus/domesticus
Length: 665  
Fragment?: false
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Protein
Q8CIB5
Organism: Mus musculus/domesticus
Length: 680  
Fragment?: false
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Protein
P59113
Organism: Mus musculus/domesticus
Length: 677  
Fragment?: false
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Protein
Q3TLE2
Organism: Mus musculus/domesticus
Length: 680  
Fragment?: false
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Protein
Q3TEE6
Organism: Mus musculus/domesticus
Length: 665  
Fragment?: false
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Protein
Q4W4Z0
Organism: Mus musculus/domesticus
Length: 491  
Fragment?: false
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Protein
A6X941
Organism: Mus musculus/domesticus
Length: 180  
Fragment?: true
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Protein
Q3UMA4
Organism: Mus musculus/domesticus
Length: 680  
Fragment?: false
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Protein
A0A494B9W3
Organism: Mus musculus/domesticus
Length: 530  
Fragment?: false
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Protein
Q6NXZ9
Organism: Mus musculus/domesticus
Length: 530  
Fragment?: false
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