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Search results 1301 to 1394 out of 1394 for Hand2

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Type Details Score
GXD Expression
GXD Expression
     
Probe: MGI:6414843
Assay Type: RT-PCR
Annotation Date: 2020-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:6415050
Age: embryonic day 9.5
Specimen Label: Wild type
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6414843
Assay Type: RT-PCR
Annotation Date: 2020-05-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:6415050
Age: embryonic day 9.5
Specimen Label: Hdn
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6414843
Assay Type: RT-PCR
Annotation Date: 2020-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:6415050
Age: embryonic day 9.5
Specimen Label: Hdn<+/em5Phg>
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6414843
Assay Type: RT-PCR
Annotation Date: 2020-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:6415050
Age: embryonic day 9.5
Specimen Label: Hdn
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:6414845
Assay Type: RT-PCR
Annotation Date: 2020-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:6415051
Age: embryonic day 9.5
Specimen Label: Wild type
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6414845
Assay Type: RT-PCR
Annotation Date: 2020-05-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:6415051
Age: embryonic day 9.5
Specimen Label: Hdn
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
       
Probe: MGI:6414845
Assay Type: RT-PCR
Annotation Date: 2020-05-06
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:6415051
Age: embryonic day 9.5
Specimen Label: Hdn<+/em5Phg>
Specimen Num: 3
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GXD Expression
GXD Expression
       
Probe: MGI:6414845
Assay Type: RT-PCR
Annotation Date: 2020-05-06
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:6415051
Age: embryonic day 9.5
Specimen Label: Hdn
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:6414843
Assay Type: RT-PCR
Annotation Date: 2020-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:6415229
Age: embryonic day 9.5
Specimen Label: None
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6414846
Assay Type: RT-PCR
Annotation Date: 2020-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:6415230
Age: embryonic day 9.5
Specimen Label: None
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6414845
Assay Type: RT-PCR
Annotation Date: 2020-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:6415231
Age: embryonic day 9.5
Specimen Label: None
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6414829
Assay Type: RNA in situ
Annotation Date: 2020-05-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640616
Pattern: Not Specified
Stage: TS16
Assay Id: MGI:6414884
Age: embryonic day 10.0
Specimen Label: 1G
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6400287
Assay Type: RNA in situ
Annotation Date: 2020-03-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1617913
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:6400339
Age: embryonic day 8.5
Image: 3B E8.5
Specimen Label: 3B E8.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6414829
Assay Type: RNA in situ
Annotation Date: 2020-05-05
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3275518
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:6414884
Age: embryonic day 11.0
Specimen Label: 1I Branchial arch
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:6400287
Assay Type: RNA in situ
Annotation Date: 2020-03-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610513
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:6400339
Age: embryonic day 8.5
Image: 3B E8.5
Note: Expression was detected in the developing heart tube and the posterior cardiac progenitors.
Specimen Label: 3B E8.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6400287
Assay Type: RNA in situ
Annotation Date: 2020-03-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610515
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:6400339
Age: embryonic day 9.5
Image: 3B E9.5
Note: Expression was detected in the developing heart tube and the posterior cardiac progenitors.
Specimen Label: 3B E9.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6414829
Assay Type: RNA in situ
Annotation Date: 2020-05-05
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1610516
Pattern: Regionally restricted
Stage: TS16
Assay Id: MGI:6414884
Age: embryonic day 10.0
Note: Weak expression was detected in the right heart loop.
Specimen Label: 1G
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6414829
Assay Type: RNA in situ
Annotation Date: 2020-05-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610514
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:6414884
Age: embryonic day 9.0
Specimen Label: 1H
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6414830
Assay Type: RNA in situ
Annotation Date: 2020-05-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603916
Stage: TS16
Assay Id: MGI:6414885
Age: embryonic day 10.0
Specimen Label: 1G
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6414829
Assay Type: RNA in situ
Annotation Date: 2020-05-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1677918
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:6414884
Age: embryonic day 11.0
Specimen Label: 1I Hind limb
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6414829
Assay Type: RNA in situ
Annotation Date: 2020-05-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1634618
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:6414884
Age: embryonic day 11.0
Specimen Label: 1I heart
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:6400287
Assay Type: RNA in situ
Annotation Date: 2020-03-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611713
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:6400339
Age: embryonic day 8.5
Image: 3B E8.5
Specimen Label: 3B E8.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6400287
Assay Type: RNA in situ
Annotation Date: 2020-03-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611715
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:6400339
Age: embryonic day 9.5
Image: 3B E9.5
Specimen Label: 3B E9.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6414829
Assay Type: RNA in situ
Annotation Date: 2020-05-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611716
Pattern: Not Specified
Stage: TS16
Assay Id: MGI:6414884
Age: embryonic day 10.0
Specimen Label: 1G
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6414829
Assay Type: RNA in situ
Annotation Date: 2020-05-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611714
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:6414884
Age: embryonic day 9.0
Specimen Label: 1H
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6414829
Assay Type: RNA in situ
Annotation Date: 2020-05-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1635018
Pattern: Regionally restricted
Stage: TS18
Assay Id: MGI:6414884
Age: embryonic day 11.0
Note: Expression was detected in the right ventricle.
Specimen Label: 1I heart
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:6400287
Assay Type: RNA in situ
Annotation Date: 2020-03-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:6400339
Age: embryonic day 9.5
Image: 3B E9.5
Specimen Label: 3B E9.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6414829
Assay Type: RNA in situ
Annotation Date: 2020-05-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640914
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:6414884
Age: embryonic day 9.0
Specimen Label: 1H
Detected: true
Specimen Num: 2
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HT Experiment
GSE210221 | Single cell evaluation of endocardial HAND2 gene regulatory networks reveals critical HAND2 dependent pathways impacting cardiac morphogenesis.
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE197858 | A spatio-temporally constrained gene regulatory network directed by PBX1/2 acquires limb patterning specificity via HAND2 [single-cell RNA-seq]
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Allele
Hdnr<em4Phg> | MGI:6400526
Name: Hand2 downstream lncRNA; endonuclease-mediated mutation 4, Phillip Grote
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Hdnr<em5Phg> | MGI:6400486
Name: Hand2 downstream lncRNA; endonuclease-mediated mutation 5, Phillip Grote
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Hdnr<em1Bbr> | MGI:6400426
Name: Hand2 downstream lncRNA; endonuclease-mediated mutation 1, Benoit G Bruneau
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Hdnr<em6Phg> | MGI:6400488
Name: Hand2 downstream lncRNA; endonuclease-mediated mutation 6, Phillip Grote
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Hdnr<em3Phg> | MGI:6400490
Name: Hand2 downstream lncRNA; endonuclease-mediated mutation 3, Phillip Grote
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Hdnr<em2Phg> | MGI:6400489
Name: Hand2 downstream lncRNA; endonuclease-mediated mutation 2, Phillip Grote
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Interaction Experiment
Thattaliyath BD (2002)
Description: The basic-helix-loop-helix transcription factor HAND2 directly regulates transcription of the atrial naturetic peptide gene.
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Strain
MGI:6414877 | B6.Cg-Hdnr<em5Phg>
Attribute String: congenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:6400482 | C57BL/6J-Hdnr<em1Bbr>
Attribute String: mutant strain, endonuclease-mediated mutation, coisogenic
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Strain
MGI:6414879 | B6.Cg-Hdnr<em6Phg>
Attribute String: mutant strain, endonuclease-mediated mutation, congenic
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Genotype
Genotype
Symbol: Hdnr/Hdnr
Background: C57BL/6J-Hdnr
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hdnr/Hdnr
Background: B6.Cg-Hdnr
Zygosity: hm
Has Mutant Allele: true
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HT Experiment
GSE131362 | Transcritptome analysis of anterior dorsal pericardial wall (aDPW) and cardiac outflow tract (OFT) from control and Hand2flox/flox; Mef2c-AHF-Cre embryos at E9.5
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Interaction Experiment
Galli A (2010)
Description: Distinct roles of Hand2 in initiating polarity and posterior Shh expression during the onset of mouse limb bud development.
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Strain
MGI:6414875 | B6.Cg-Hdnr<em2Phg>/Hdnr<em4Phg>
Attribute String: mutant strain, endonuclease-mediated mutation, congenic
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Genotype
Genotype
Symbol: Hdnr/Hdnr
Background: B6.Cg-Hdnr/Hdnr
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hdnr/Hdnr<+>
Background: B6.Cg-Hdnr
Zygosity: ht
Has Mutant Allele: true
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Allele
Tg(Hand2)#Tshir | MGI:5518842
Name: transgene insertion, Toshihiko Shiroishi
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Tg(Hand2)#Tshir/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
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Allele
Tg(Hand2-cre)7-1Clou | MGI:3056567
Name: transgene insertion 7-1, David E Clouthier
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(Prrx1-Hand2)1Eno | MGI:2446334
Name: transgene insertion 1, Eric N Olson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prrx1-Hand2)7Eno | MGI:2446345
Name: transgene insertion 7, Eric N Olson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prrx1-Hand2)6Eno | MGI:2446344
Name: transgene insertion 6, Eric N Olson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Hand2<tm3Zllr> | MGI:6450796
Name: heart and neural crest derivatives expressed 2; targeted mutation 3, Rolf Zeller
Allele Type: Targeted
Attribute String: Epitope tag, RMCE-ready
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Allele
Tg(Prrx1-Hand2)5Eno | MGI:2446342
Name: transgene insertion 5, Eric N Olson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prrx1-Hand2/VP16)1Eno | MGI:2446351
Name: transgene insertion 1, Eric N Olson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prrx1-Hand2)3Eno | MGI:2446339
Name: transgene insertion 3, Eric N Olson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prrx1-Hand2)2Eno | MGI:2446336
Name: transgene insertion 2, Eric N Olson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prrx1-Hand2)4Eno | MGI:2446340
Name: transgene insertion 4, Eric N Olson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prrx1-Hand2)8Eno | MGI:2446350
Name: transgene insertion 8, Eric N Olson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Tg(Prrx1-Hand2)2Eno/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prrx1-Hand2/VP16)1Eno/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prrx1-Hand2)3Eno/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prrx1-Hand2)1Eno/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prrx1-Hand2)4Eno/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prrx1-Hand2)6Eno/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prrx1-Hand2)8Eno/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prrx1-Hand2)5Eno/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prrx1-Hand2)7Eno/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ednra/Ednra Tg(Hand2-cre)7-1Clou/?
Background: involves: C57BL/6J * SJL
Zygosity: cn
Has Mutant Allele: true
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HT Experiment
GSE164737 | Chromatin remodeling and expression dynamics reveal conserved and species-specific regulation during mouse and chicken limb development [RNA-seq]
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Hand2-cre)7-1Clou/?
Background: involves: 129
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Hand2-cre)7-1Clou/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Publication
17420000 | J:122483
First Author: Verzi MP
Year: 2007
Journal: Dev Cell
Title: The transcription factor MEF2C is required for craniofacial development.
Volume: 12
Issue: 4
Pages: 645-52
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Publication
25980517 | J:224873
 
First Author: Noseda M
Year: 2015
Journal: Nat Commun
Title: PDGFRα demarcates the cardiogenic clonogenic Sca1+ stem/progenitor cell in adult murine myocardium.
Volume: 6
Pages: 6930
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Genotype
Genotype
Symbol: Ednra/Ednra Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Hand2-cre)7-1Clou/?
Background: involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6J * SJL
Zygosity: cn
Has Mutant Allele: true
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Publication
31219639 | J:279375
First Author: Fritz KR
Year: 2019
Journal: Dev Dyn
Title: Cdc42 activation by endothelin regulates neural crest cell migration in the cardiac outflow tract.
Volume: 248
Issue: 9
Pages: 795-812
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Publication
37664846 | J:341508
 
First Author: Oh Y
Year: 2023
Journal: Front Endocrinol (Lausanne)
Title: The NR2F2-HAND2 signaling axis regulates progesterone actions in the uterus at early pregnancy.
Volume: 14
Pages: 1229033
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Publication
25344074 | J:244244
First Author: Nam YJ
Year: 2014
Journal: Development
Title: Induction of diverse cardiac cell types by reprogramming fibroblasts with cardiac transcription factors.
Volume: 141
Issue: 22
Pages: 4267-78
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Publication
38426493 | J:345636
 
First Author: Xin Q
Year: 2024
Journal: J Clin Invest
Title: Stromal Pbrm1 mediates chromatin remodeling necessary for embryo implantation in the mouse uterus.
Volume: 134
Issue: 5
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Publication
16943277 | J:119569
First Author: Moriguchi T
Year: 2006
Journal: Development
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