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Search results 201 to 205 out of 205 for Slc12a8

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Type Details Score
Publication
First Author: Gagnon KB
Year: 2013
Journal: Am J Physiol Cell Physiol
Title: Physiology of SLC12 transporters: lessons from inherited human genetic mutations and genetically engineered mouse knockouts.
Volume: 304
Issue: 8
Pages: C693-714
Protein Domain
Type: Family
Description: The electroneutral cation-chloride-coupled cotransporter gene family (SLC12) consists of nine members and encompasses two major branches. One brach includes three genes (SLC12A1-SLC12A3) encoding two bumetanide-sensitive Na+-K+-2Cl- cotransporters (NKC) and a thiazide-sensitive Na+:Cl- cotransporter (NC). The second branch includes four genes (SLC12A4-7) encoding electroneutral K+-Cl- cotransporters (KCC). The transported substrates of the remaining two SLC12 family members, SLC12A8 and SLC12A9, are unknown [].This entry represents SLC12A9. No physiological role has been ascribed to SLC12A9 [, ].
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Slc12a8/Slc12a8<+>
Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Slc12a8/Slc12a8<+>
Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
Protein
Organism: Mus musculus/domesticus
Length: 60  
Fragment?: true