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Search results 401 to 500 out of 537 for Isg15

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0.036s

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Hits by Pathway

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Type Details Score
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1860128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855228
Specimen Label: UC Davis_1855228
Detected: true
Specimen Num: 32
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1860128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855229
Specimen Label: UC Davis_1855229
Detected: true
Specimen Num: 33
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1842628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855197
Specimen Label: UC Davis_1855197
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1842628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855198
Specimen Label: UC Davis_1855198
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1842628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855199
Specimen Label: UC Davis_1855199
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3556128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855242
Specimen Label: UC Davis_1855242
Detected: true
Specimen Num: 44
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3556128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855243
Specimen Label: UC Davis_1855243
Detected: true
Specimen Num: 45
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1893928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855195
Specimen Label: UC Davis_1855195
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1893928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855143
Specimen Label: UC Davis_1855143
Detected: true
Specimen Num: 58
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1893928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855144
Specimen Label: UC Davis_1855144
Detected: true
Specimen Num: 59
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1898628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855247
Specimen Label: UC Davis_1855247
Detected: true
Specimen Num: 49
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1718528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855221
Specimen Label: UC Davis_1855221
Detected: true
Specimen Num: 26
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1866628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855240
Specimen Label: UC Davis_1855240
Detected: true
Specimen Num: 42
•
•
•
•
•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1918028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855189
Note: vesicular gland
Specimen Label: UC Davis_1855189
Detected: true
Specimen Num: 98
•
•
•
•
•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1918028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855190
Note: vesicular gland
Specimen Label: UC Davis_1855190
Detected: true
Specimen Num: 99
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855256
Specimen Label: UC Davis_1855256
Detected: true
Specimen Num: 100
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855171
Specimen Label: UC Davis_1855171
Detected: true
Specimen Num: 83
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855172
Specimen Label: UC Davis_1855172
Detected: true
Specimen Num: 84
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855173
Specimen Label: UC Davis_1855173
Detected: true
Specimen Num: 85
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1928728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855257
Specimen Label: UC Davis_1855257
Detected: true
Specimen Num: 101
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1928728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855258
Specimen Label: UC Davis_1855258
Detected: true
Specimen Num: 102
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1928728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855180
Specimen Label: UC Davis_1855180
Detected: true
Specimen Num: 92
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1832128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855244
Specimen Label: UC Davis_1855244
Detected: true
Specimen Num: 46
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1832128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855219
Specimen Label: UC Davis_1855219
Detected: true
Specimen Num: 24
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1832128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855168
Specimen Label: UC Davis_1855168
Detected: true
Specimen Num: 80
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1832128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855169
Specimen Label: UC Davis_1855169
Detected: true
Specimen Num: 81
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1832128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855170
Specimen Label: UC Davis_1855170
Detected: true
Specimen Num: 82
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3599828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855237
Specimen Label: UC Davis_1855237
Detected: true
Specimen Num: 39
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3599828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855200
Specimen Label: UC Davis_1855200
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3599828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855201
Specimen Label: UC Davis_1855201
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3599828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855148
Specimen Label: UC Davis_1855148
Detected: true
Specimen Num: 63
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855207
Specimen Label: UC Davis_1855207
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855208
Specimen Label: UC Davis_1855208
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855159
Specimen Label: UC Davis_1855159
Detected: true
Specimen Num: 74
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855160
Specimen Label: UC Davis_1855160
Detected: true
Specimen Num: 75
•
•
•
•
•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1802528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855253
Note: chest bone
Specimen Label: UC Davis_1855253
Detected: true
Specimen Num: 52
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855239
Specimen Label: UC Davis_1855239
Detected: true
Specimen Num: 41
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855192
Specimen Label: UC Davis_1855192
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855193
Specimen Label: UC Davis_1855193
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855139
Specimen Label: UC Davis_1855139
Detected: true
Specimen Num: 54
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855140
Specimen Label: UC Davis_1855140
Detected: true
Specimen Num: 55
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855141
Specimen Label: UC Davis_1855141
Detected: true
Specimen Num: 56
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855142
Specimen Label: UC Davis_1855142
Detected: true
Specimen Num: 57
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855174
Specimen Label: UC Davis_1855174
Detected: true
Specimen Num: 86
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855175
Specimen Label: UC Davis_1855175
Detected: true
Specimen Num: 87
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855176
Specimen Label: UC Davis_1855176
Detected: true
Specimen Num: 88
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855177
Specimen Label: UC Davis_1855177
Detected: true
Specimen Num: 89
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855178
Specimen Label: UC Davis_1855178
Detected: true
Specimen Num: 90
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855179
Specimen Label: UC Davis_1855179
Detected: true
Specimen Num: 91
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855241
Specimen Label: UC Davis_1855241
Detected: true
Specimen Num: 43
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855194
Specimen Label: UC Davis_1855194
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1915328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855238
Specimen Label: UC Davis_1855238
Detected: true
Specimen Num: 40
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1915328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855205
Specimen Label: UC Davis_1855205
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1915328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855206
Specimen Label: UC Davis_1855206
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1915328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855158
Specimen Label: UC Davis_1855158
Detected: true
Specimen Num: 73
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855234
Specimen Label: UC Davis_1855234
Detected: true
Specimen Num: 36
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855235
Specimen Label: UC Davis_1855235
Detected: true
Specimen Num: 37
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855236
Specimen Label: UC Davis_1855236
Detected: true
Specimen Num: 38
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855149
Specimen Label: UC Davis_1855149
Detected: true
Specimen Num: 64
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855150
Specimen Label: UC Davis_1855150
Detected: true
Specimen Num: 65
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855151
Specimen Label: UC Davis_1855151
Detected: true
Specimen Num: 66
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3281228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855248
Specimen Label: UC Davis_1855248
Detected: true
Specimen Num: 50
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3281228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855136
Specimen Label: UC Davis_1855136
Detected: true
Specimen Num: 53
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855246
Specimen Label: UC Davis_1855246
Detected: true
Specimen Num: 48
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855218
Specimen Label: UC Davis_1855218
Detected: true
Specimen Num: 23
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855227
Specimen Label: UC Davis_1855227
Detected: true
Specimen Num: 31
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855181
Specimen Label: UC Davis_1855181
Detected: true
Specimen Num: 93
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692544
Age: postnatal adult
Image: UC Davis_1855182
Specimen Label: UC Davis_1855182
Detected: true
Specimen Num: 94
•
•
•
•
•
Publication
18078692 | -
First Author: Frias-Staheli N
Year: 2007
Journal: Cell Host Microbe
Title: Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses.
Volume: 2
Issue: 6
Pages: 404-16
•
•
•
•
•
Protein Domain
IPR023183 | Chymotrypsin-like_C
Type: Homologous_superfamily
Description: The replicase polyprotein 1ab is a multifunctional protein: it contains the activities necessary for the transcription of negative stranded RNA, leader RNA, subgenomic mRNAs and progeny virion RNA as well as proteinases responsible for the cleavage of the polyprotein into functional products. Nsp1 is essential for viral subgenomic mRNA synthesis. Nsp2 cysteine proteinase which cleaves the Nsp2/Nsp3 site in the polyprotein. Also displays deubiquitinating and deISGylase activities. The deubiquitinating activity cleaves both ubiquitinated and ISGylated products and may therefore regulate ubiquitin and ISG15 dependent host innate immunity. The 3C-like serine proteinase chain (Nsp4) is responsible for the majority of cleavages as it cleaves the C terminus of the polyprotein. The helicase chain, which contains a zinc finger structure, displays RNA and DNA duplex-unwinding activities with 5' to 3' polarity [].This superfamily represents the C-terminal domain of chymotrypsin-like serine proteinase Nsp4. Nsp4 contains two β-barrels, known as N- and C-terminal barrels, as well as a unique C-terminal domain. The C-terminal domain consists of two short pairs of β-strands and two α-helices. It interacts with the C-terminal barrel through an interface consisting of conserved hydrophobic residues: Leu-105 and Leu-112 from the C-terminal β-barrel and Val-158, Leu-163, Phe-167, Ile-182, Leu-196, and Ile-197 from the C-terminal domain. There is also an exposed patch of conserved solvent-exposed hydrophobic residues that may form part of the interface with Nsp5 in the Nsp4-5 intermediate []. This hydrophobic patch may also mediate interactions with Nsp2, which associates with Nsp3-8 to induce cleavage of the Nsp4-5 site by Nsp4 []. The C-terminal domain can clearly adopt different orientations relative to the two β-barrels, which may facilitate substrate binding or autoproteolysis [].
•
•
•
•
•
Protein Coding Gene
MGI:97615 | Plcg1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein
P52482
Organism: Mus musculus/domesticus
Length: 193  
Fragment?: false
•
•
•
•
•
Protein
Q62077
Organism: Mus musculus/domesticus
Length: 1302  
Fragment?: false
•
•
•
•
•
Publication
17686841 | J:127942
First Author: Zhang Y
Year: 2007
Journal: J Virol
Title: Identification and characterization of interferon-induced proteins that inhibit alphavirus replication.
Volume: 81
Issue: 20
Pages: 11246-55
•
•
•
•
•
Publication
22491252 | J:188680
First Author: Cong XL
Year: 2012
Journal: J Immunol
Title: Usp18 promotes conventional CD11b+ dendritic cell development.
Volume: 188
Issue: 10
Pages: 4776-81
•
•
•
•
•
Publication
22753500 | J:186490
First Author: Maier HJ
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Cardiomyocyte-specific IκB kinase (IKK)/NF-κB activation induces reversible inflammatory cardiomyopathy and heart failure.
Volume: 109
Issue: 29
Pages: 11794-9
•
•
•
•
•
Publication
37483625 | J:338524
 
First Author: Huang Z
Year: 2023
Journal: Front Immunol
Title: Integrated analyses of single-cell transcriptomics identify metastasis-associated myeloid subpopulations in breast cancer lung metastasis.
Volume: 14
Pages: 1180402
•
•
•
•
•
Publication
25406959 | J:330459
First Author: Arimoto K
Year: 2015
Journal: J Interferon Cytokine Res
Title: Murine Herc6 Plays a Critical Role in Protein ISGylation In Vivo and Has an ISGylation-Independent Function in Seminal Vesicles.
Volume: 35
Issue: 5
Pages: 351-8
•
•
•
•
•
Publication
12604599 | J:83214
First Author: Yang H
Year: 2003
Journal: J Biol Chem
Title: Interferon regulatory factor-7 synergizes with other transcription factors through multiple interactions with p300/CBP coactivators.
Volume: 278
Issue: 18
Pages: 15495-504
•
•
•
•
•
Publication
19289497 | J:148986
First Author: Kroczynska B
Year: 2009
Journal: Mol Cell Biol
Title: Interferon-dependent engagement of eukaryotic initiation factor 4B via S6 kinase (S6K)- and ribosomal protein S6K-mediated signals.
Volume: 29
Issue: 10
Pages: 2865-75
•
•
•
•
•
Publication
19574459 | J:150797
First Author: Joshi S
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Type I interferon (IFN)-dependent activation of Mnk1 and its role in the generation of growth inhibitory responses.
Volume: 106
Issue: 29
Pages: 12097-102
•
•
•
•
•
Publication
23074222 | J:197120
First Author: Sharma B
Year: 2012
Journal: J Biol Chem
Title: Sprouty proteins are negative regulators of interferon (IFN) signaling and IFN-inducible biological responses.
Volume: 287
Issue: 50
Pages: 42352-60
•
•
•
•
•
Publication
25049393 | J:212231
First Author: Kroczynska B
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Regulatory effects of SKAR in interferon α signaling and its role in the generation of type I IFN responses.
Volume: 111
Issue: 31
Pages: 11377-82
•
•
•
•
•
Publication
30842212 | J:292136
First Author: Wang P
Year: 2019
Journal: Gut
Title: Diverse tumour susceptibility in Collaborative Cross mice: identification of a new mouse model for human gastric tumourigenesis.
Volume: 68
Issue: 11
Pages: 1942-1952
•
•
•
•
•
Publication
33380466 | J:303973
First Author: Liu X
Year: 2021
Journal: Mol Cancer Res
Title: The Ubiquitin-Specific Peptidase USP18 Promotes Lipolysis, Fatty Acid Oxidation, and Lung Cancer Growth.
Volume: 19
Issue: 4
Pages: 667-677
•
•
•
•
•
Publication
33531496 | -
First Author: Osipiuk J
Year: 2021
Journal: Nat Commun
Title: Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors.
Volume: 12
Issue: 1
Pages: 743
•
•
•
•
•
Publication
12163505 | -
First Author: Barrette-Ng IH
Year: 2002
Journal: J Biol Chem
Title: Structure of arterivirus nsp4. The smallest chymotrypsin-like proteinase with an alpha/beta C-terminal extension and alternate conformations of the oxyanion hole.
Volume: 277
Issue: 42
Pages: 39960-6
•
•
•
•
•
Protein Domain
IPR013016 | Peptidase_C16_CoV
Type: Domain
Description: This entry contains coronavirus (CoV) cysteine endopeptidases that belong to MEROPS peptidase family C16 (subfamilies C16A and C16B, clan CA). These peptidases are involved in viral polyprotein processing, releasing NSP1, NSP2 and NSP3 proteins []and they also function as deubiquitinating and deISG15ylating (interferon-induced gene 15) enzymes, disrupting host viral immune response to facilitate viral proliferation and replication. Therefore, this is an important target to develop antiviral treatments [].All coronaviruses encode between one and two accessory cysteine proteinases that recognise and process one or three sites in the amino-terminal half of the replicase polyprotein during assembly of the viral replication complex. MHV, HCoV and TGEV encode two accessory proteinases, called coronavirus papain-like proteinase 1 and 2 (PL1-PRO and PL2-PRO) []. IBV and SARS encodes only one called PL-PRO (PL2-PRO, conserved in all CoVs) [, , ]. The structures of both PL-PROs are similar and they also have restricted specificities. The PL1-PRO of TGEV cleaves the polyprotein between Nsp2-Nsp3 recognising the Lys-Met-Gly-Gly motif, and recognises Leu-Arg-Gly-Gly in ubiquitin (ub) which shows that it is able to accommodate residues as different as Lys and Leu. In contrast, PL-PRO from SARS-CoV recognises Leu-Xaa-Gly-Gly (Xaa could be any amino acid) and cleaves peptide bonds between Nsp1-Nsp2, Nsp2-Nsp3 and between Nsp3-Nsp4 [, , ]. In Ub and ISG15 proteins, it recognises Leu-Arg-Gly-Gly motifs. SARS-CoV and SARS-CoV-2 are closely related but exhibit different host substrate preferences: SARS-CoV-2 PL-PRO preferentially cleaves the ubiquitin-like ISG15, whereas SARS-CoV PL-PRO predominantly targets ubiquitin chains [, ].The peptidase family C16 domain is about 260 amino acids in length and the solved structures determined that it consists of thumb, palm, and fingers subdomains. The thumb is comprised of six α-helices and a small β-hairpin; the fingers subdomain is made of six β-strands and two α-helices and includes a zinc binding site, in which the zinc ion is coordinated by four cysteine residues. Zinc binding is essential for structural integrity and protease activity, with a conformation that varies most between different PL-PRO structures. The palm subdomain is comprised of six β-strands and includes the catalytic residues Cys-His-Asp, located at the interface between the thumb and palm subdomains [].
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•
•
•
•
Publication
23557705 | J:208970
First Author: Marcelin G
Year: 2013
Journal: Diabetes
Title: Identification of a loss-of-function mutation in Ube2l6 associated with obesity resistance.
Volume: 62
Issue: 8
Pages: 2784-95
•
•
•
•
•
Protein Coding Gene
MGI:1934835 | Ube2n
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein
P61089
Organism: Mus musculus/domesticus
Length: 152  
Fragment?: false
•
•
•
•
•
Publication
15644321 | J:97767
First Author: Li Y
Year: 2005
Journal: J Biol Chem
Title: Activation of mitogen-activated protein kinase kinase (MKK) 3 and MKK6 by type I interferons.
Volume: 280
Issue: 11
Pages: 10001-10
•
•
•
•
•
Publication
26892877 | J:236756
 
First Author: Bröer S
Year: 2016
Journal: Exp Neurol
Title: Brain inflammation, neurodegeneration and seizure development following picornavirus infection markedly differ among virus and mouse strains and substrains.
Volume: 279
Pages: 57-74
•
•
•
•
•
Publication
26709698 | J:236763
First Author: Kroetz DN
Year: 2015
Journal: PLoS Pathog
Title: Type I Interferon Induced Epigenetic Regulation of Macrophages Suppresses Innate and Adaptive Immunity in Acute Respiratory Viral Infection.
Volume: 11
Issue: 12
Pages: e1005338
•
•
•
•
•
Publication
35073761 | J:331808
First Author: Pan R
Year: 2022
Journal: mBio
Title: N7-Methylation of the Coronavirus RNA Cap Is Required for Maximal Virulence by Preventing Innate Immune Recognition.
Volume: 13
Issue: 1
Pages: e0366221
•
•
•
•
•
Protein Coding Gene
MGI:1346859 | Mapk3
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein
Q63844
Organism: Mus musculus/domesticus
Length: 380  
Fragment?: false
•
•
•
•
•
Publication
10508511 | J:57881
First Author: Persons DA
Year: 1999
Journal: Nat Genet
Title: Fv2 encodes a truncated form of the Stk receptor tyrosine kinase.
Volume: 23
Issue: 2
Pages: 159-65
•
•
•
•
•
Publication
8396668 | -
First Author: Baker SC
Year: 1993
Journal: J Virol
Title: Identification of the catalytic sites of a papain-like cysteine proteinase of murine coronavirus.
Volume: 67
Issue: 10
Pages: 6056-63
•
•
•
•
•
Publication
9371590 | -
First Author: Wassenaar AL
Year: 1997
Journal: J Virol
Title: Alternative proteolytic processing of the arterivirus replicase ORF1a polyprotein: evidence that NSP2 acts as a cofactor for the NSP4 serine protease.
Volume: 71
Issue: 12
Pages: 9313-22
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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