Type |
Details |
Score |
Publication |
First Author: |
Bulfone A |
Year: |
2005 |
Journal: |
J Neurosci |
Title: |
Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes. |
Volume: |
25 |
Issue: |
33 |
Pages: |
7586-600 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
MGC Data curation in Mouse Genome Informatics |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Yokoyama S |
Year: |
2009 |
Journal: |
Dev Cell |
Title: |
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. |
Volume: |
17 |
Issue: |
6 |
Pages: |
836-48 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen J |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
Volume: |
100 |
Issue: |
17 |
Pages: |
9918-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Friedel RH |
Year: |
2007 |
Journal: |
Brief Funct Genomic Proteomic |
Title: |
EUCOMM--the European conditional mouse mutagenesis program. |
Volume: |
6 |
Issue: |
3 |
Pages: |
180-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2018 |
Journal: |
Database Release |
Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Gray PA |
Year: |
2004 |
Journal: |
Science |
Title: |
Mouse brain organization revealed through direct genome-scale TF expression analysis. |
Volume: |
306 |
Issue: |
5705 |
Pages: |
2255-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GUDMAP Consortium |
Year: |
2004 |
Journal: |
www.gudmap.org |
Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Interaction Experiment |
Description: |
The Polycomb-associated protein Rybp is a ubiquitin binding protein. |
|
•
•
•
•
•
|
Publication |
First Author: |
Stanton SE |
Year: |
2007 |
Journal: |
Apoptosis |
Title: |
Rybp interacts with Hippi and enhances Hippi-mediated apoptosis. |
Volume: |
12 |
Issue: |
12 |
Pages: |
2197-206 |
|
•
•
•
•
•
|
Interaction Experiment |
Description: |
RNA Helicase DDX5 Inhibits Reprogramming to Pluripotency by miRNA-Based Repression of RYBP and its PRC1-Dependent and -Independent Functions. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Proteins included in this entry have an N-terminal RanBP2-type zinc finger and a Yaf2/RYBP C-terminal binding motif. Proteins with these regions include Yaf2 and RYBP proteins, which are homologous parts of the PRC1 complex [].RYBP is a zinc finger protein with an essential role during embryonic development, which binds transcriptional factors, Polycomb products, and mediators of apoptosisis []. RYBP also binds ubiquitin and Cbx proteins via the C-terminal docking module [, ]. RYBP is natively unstructured until it binds to the C-terminal region of the Polycomb protein Ring1B or to DNA []. Yaf2 binds to MYC and inhibits MYC-mediated transactivation []. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Conserved_site |
Description: |
This motif is found in the C-terminal region of the Yaf2 and RYBP proteins, which are homologous parts of the PRC1 complex [].RYBP is a zinc finger protein with an essential role during embryonic development, which binds transcriptional factors, Polycomb products, and mediators of apoptosisis []. RYBP also binds ubiquitin and Cbx proteins via the C-terminal docking module [, ]. RYBP is natively unstructured until it binds to the C-terminal region of the Polycomb protein Ring1B or to DNA []. Yaf2 binds to MYC and inhibits MYC-mediated transactivation []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang R |
Year: |
2010 |
Journal: |
Structure |
Title: |
Polycomb group targeting through different binding partners of RING1B C-terminal domain. |
Volume: |
18 |
Issue: |
8 |
Pages: |
966-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bannasch D |
Year: |
2001 |
Journal: |
Oncogene |
Title: |
Functional interaction of Yaf2 with the central region of MycN. |
Volume: |
20 |
Issue: |
41 |
Pages: |
5913-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bezsonova I |
Year: |
2009 |
Journal: |
Biochemistry |
Title: |
Ring1B contains a ubiquitin-like docking module for interaction with Cbx proteins. |
Volume: |
48 |
Issue: |
44 |
Pages: |
10542-8 |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Pseudogene |
Type: |
pseudogene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
228
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
179
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhao JL |
Year: |
2016 |
Journal: |
Cancer Res |
Title: |
Forced Activation of Notch in Macrophages Represses Tumor Growth by Upregulating miR-125a and Disabling Tumor-Associated Macrophages. |
Volume: |
76 |
Issue: |
6 |
Pages: |
1403-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Trimarchi JM |
Year: |
2001 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex. |
Volume: |
98 |
Issue: |
4 |
Pages: |
1519-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Basu A |
Year: |
2014 |
Journal: |
Nucleic Acids Res |
Title: |
YY1 DNA binding and interaction with YAF2 is essential for Polycomb recruitment. |
Volume: |
42 |
Issue: |
4 |
Pages: |
2208-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhao W |
Year: |
2018 |
Journal: |
J Biol Chem |
Title: |
The polycomb group protein Yaf2 regulates the pluripotency of embryonic stem cells in a phosphorylation-dependent manner. |
Volume: |
293 |
Issue: |
33 |
Pages: |
12793-12804 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|