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Search results 1 to 100 out of 119 for Alox12

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Type Details Score
Publication
31277941 | J:291099
First Author: Li JL
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Knockout of ALOX12 protects against spinal cord injury-mediated nerve injury by inhibition of inflammation and apoptosis.
Volume: 516
Issue: 3
Pages: 991-998
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Publication
30962574 | J:282892
First Author: Chu B
Year: 2019
Journal: Nat Cell Biol
Title: ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway.
Volume: 21
Issue: 5
Pages: 579-591
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Publication
7868854 | J:24098
First Author: Nakamura M
Year: 1995
Journal: J Histochem Cytochem
Title: Immunocytochemical localization of platelet-type arachidonate 12-lipoxygenase in mouse blood cells.
Volume: 43
Issue: 3
Pages: 237-44
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Publication
9501222 | J:46896
First Author: Johnson EN
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Increased platelet sensitivity to ADP in mice lacking platelet-type 12-lipoxygenase.
Volume: 95
Issue: 6
Pages: 3100-5
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Publication
10383730 | J:55741
First Author: Johnson EN
Year: 1999
Journal: J Invest Dermatol
Title: Basal transepidermal water loss is increased in platelet-type 12-lipoxygenase deficient mice.
Volume: 112
Issue: 6
Pages: 861-5
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Publication
25293588 | J:277856
First Author: Teder T
Year: 2014
Journal: J Lipid Res
Title: Lipoxygenase-catalyzed transformation of epoxy fatty acids to hydroxy-endoperoxides: a potential P450 and lipoxygenase interaction.
Volume: 55
Issue: 12
Pages: 2587-96
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Publication
7576099 | J:30181
First Author: Krieg P
Year: 1995
Journal: Mol Carcinog
Title: 12-Lipoxygenase isoenzymes in mouse skin tumor development.
Volume: 14
Issue: 2
Pages: 118-29
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Publication
8188678 | J:18190
First Author: Chen XS
Year: 1994
Journal: J Biol Chem
Title: cDNA cloning, expression, mutagenesis of C-terminal isoleucine, genomic structure, and chromosomal localizations of murine 12-lipoxygenases.
Volume: 269
Issue: 19
Pages: 13979-87
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Publication
11256953 | J:276497
First Author: Siebert M
Year: 2001
Journal: Biochem J
Title: Enzymic characterization of epidermis-derived 12-lipoxygenase isoenzymes.
Volume: 355
Issue: Pt 1
Pages: 97-104
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Publication
34910546 | J:344061
First Author: Zhang XJ
Year: 2021
Journal: Sci Transl Med
Title: Multiple omics study identifies an interspecies conserved driver for nonalcoholic steatohepatitis.
Volume: 13
Issue: 624
Pages: eabg8117
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Publication
34910548 | J:344062
First Author: Zhang XJ
Year: 2021
Journal: Sci Transl Med
Title: A small molecule targeting ALOX12-ACC1 ameliorates nonalcoholic steatohepatitis in mice and macaques.
Volume: 13
Issue: 624
Pages: eabg8116
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Publication
34536344 | J:321719
First Author: Zhang XJ
Year: 2021
Journal: Cell Metab
Title: Pharmacological inhibition of arachidonate 12-lipoxygenase ameliorates myocardial ischemia-reperfusion injury in multiple species.
Volume: 33
Issue: 10
Pages: 2059-2075.e10
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Publication
29227475 | J:281185
First Author: Zhang XJ
Year: 2018
Journal: Nat Med
Title: An ALOX12-12-HETE-GPR31 signaling axis is a key mediator of hepatic ischemia-reperfusion injury.
Volume: 24
Issue: 1
Pages: 73-83
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Publication
30792307 | J:277934
First Author: Conteh AM
Year: 2019
Journal: J Biol Chem
Title: Platelet-type 12-lipoxygenase deletion provokes a compensatory 12/15-lipoxygenase increase that exacerbates oxidative stress in mouse islet β cells.
Volume: 294
Issue: 16
Pages: 6612-6620
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Publication
14676201 | J:88509
First Author: Reilly KB
Year: 2004
Journal: J Biol Chem
Title: 12/15-Lipoxygenase activity mediates inflammatory monocyte/endothelial interactions and atherosclerosis in vivo.
Volume: 279
Issue: 10
Pages: 9440-50
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Publication
23784669 | J:268842
First Author: Yeung J
Year: 2013
Journal: Thromb Haemost
Title: 12-lipoxygenase activity plays an important role in PAR4 and GPVI-mediated platelet reactivity.
Volume: 110
Issue: 3
Pages: 569-81
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Publication
26106157 | J:223733
First Author: Duchez AC
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A2-IIA.
Volume: 112
Issue: 27
Pages: E3564-73
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Publication
20599608 | J:164459
First Author: Stavniichuk R
Year: 2010
Journal: Free Radic Biol Med
Title: Role of 12/15-lipoxygenase in nitrosative stress and peripheral prediabetic and diabetic neuropathies.
Volume: 49
Issue: 6
Pages: 1036-45
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Publication
28775075 | J:269222
First Author: Adili R
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: First Selective 12-LOX Inhibitor, ML355, Impairs Thrombus Formation and Vessel Occlusion In Vivo With Minimal Effects on Hemostasis.
Volume: 37
Issue: 10
Pages: 1828-1839
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Publication
11299195 | J:69296
First Author: Gabel SA
Year: 2001
Journal: Am J Physiol Heart Circ Physiol
Title: Leukocyte-type 12-lipoxygenase-deficient mice show impaired ischemic preconditioning-induced cardioprotection.
Volume: 280
Issue: 5
Pages: H1963-9
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Publication
27470510 | J:249039
First Author: Yeung J
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: 12(S)-HETrE, a 12-Lipoxygenase Oxylipin of Dihomo-γ-Linolenic Acid, Inhibits Thrombosis via Gαs Signaling in Platelets.
Volume: 36
Issue: 10
Pages: 2068-77
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25245389 | J:327163
First Author: Abraham NG
Year: 2014
Journal: Hypertension
Title: CYP2J2 targeting to endothelial cells attenuates adiposity and vascular dysfunction in mice fed a high-fat diet by reprogramming adipocyte phenotype.
Volume: 64
Issue: 6
Pages: 1352-61
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15161019 | J:117441
First Author: Ikemoto S
Year: 2004
Journal: Anticancer Res
Title: Antitumor effects of lipoxygenase inhibitors on murine bladder cancer cell line (MBT-2).
Volume: 24
Issue: 2B
Pages: 733-6
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Publication
- | J:47529
First Author: Nakamura M
Year: 1998
Journal: Acta Histochem Cytochem
Title: Platelet-type arachidonate 12-lipoxygenase in mouse gastrointestinal tract.
Volume: 31
Issue: 1
Pages: 71-75
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Publication
15708862 | J:98733
First Author: Gronert K
Year: 2005
Journal: J Biol Chem
Title: A role for the mouse 12/15-lipoxygenase pathway in promoting epithelial wound healing and host defense.
Volume: 280
Issue: 15
Pages: 15267-78
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Publication
22215650 | J:184646
First Author: Cole BK
Year: 2012
Journal: Am J Physiol Endocrinol Metab
Title: 12/15-Lipoxygenase signaling in the endoplasmic reticulum stress response.
Volume: 302
Issue: 6
Pages: E654-65
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Publication
17045234 | J:116329
First Author: Yu Z
Year: 2006
Journal: Arch Biochem Biophys
Title: Human and mouse eLOX3 have distinct substrate specificities: implications for their linkage with lipoxygenases in skin.
Volume: 455
Issue: 2
Pages: 188-96
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Publication
20724598 | J:163914
First Author: Obrosova IG
Year: 2010
Journal: Am J Pathol
Title: Different roles of 12/15-lipoxygenase in diabetic large and small fiber peripheral and autonomic neuropathies.
Volume: 177
Issue: 3
Pages: 1436-47
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24300237 | J:212733
First Author: Joshi YB
Year: 2014
Journal: Neurobiol Aging
Title: Overexpression of 12/15-lipoxygenase increases anxiety behavior in female mice.
Volume: 35
Issue: 5
Pages: 1032-6
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Publication
23664097 | J:199008
First Author: Kang KH
Year: 2013
Journal: Eur J Cancer
Title: Enhancement role of host 12/15-lipoxygenase in melanoma progression.
Volume: 49
Issue: 12
Pages: 2747-59
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Publication
19675173 | J:151843
First Author: Krönke G
Year: 2009
Journal: J Immunol
Title: 12/15-lipoxygenase counteracts inflammation and tissue damage in arthritis.
Volume: 183
Issue: 5
Pages: 3383-9
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Publication
29184033 | J:260300
 
First Author: Lauder SN
Year: 2017
Journal: Sci Signal
Title: Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis.
Volume: 10
Issue: 507
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21220563 | J:171537
First Author: Kenchegowda S
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: EGF stimulates lipoxin A4 synthesis and modulates repair in corneal epithelial cells through ERK and p38 activation.
Volume: 52
Issue: 5
Pages: 2240-9
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25187369 | J:247246
First Author: Suzuki H
Year: 2015
Journal: Diabetes
Title: Arachidonate 12/15-lipoxygenase-induced inflammation and oxidative stress are involved in the development of diabetic cardiomyopathy.
Volume: 64
Issue: 2
Pages: 618-30
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19373248 | J:164179
First Author: Park HA
Year: 2009
Journal: Cell Death Differ
Title: Glutathione disulfide induces neural cell death via a 12-lipoxygenase pathway.
Volume: 16
Issue: 8
Pages: 1167-79
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10330425 | J:55050
First Author: Bleich D
Year: 1999
Journal: J Clin Invest
Title: Resistance to type 1 diabetes induction in 12-lipoxygenase knockout mice.
Volume: 103
Issue: 10
Pages: 1431-6
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19787041 | J:153592
First Author: Sears DD
Year: 2009
Journal: PLoS One
Title: 12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice.
Volume: 4
Issue: 9
Pages: e7250
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Publication
25251155 | J:223495
First Author: Lazic M
Year: 2014
Journal: PLoS One
Title: Reduced dietary omega-6 to omega-3 fatty acid ratio and 12/15-lipoxygenase deficiency are protective against chronic high fat diet-induced steatohepatitis.
Volume: 9
Issue: 9
Pages: e107658
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Publication
18780776 | J:142615
First Author: Nunemaker CS
Year: 2008
Journal: Am J Physiol Endocrinol Metab
Title: 12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by Western diet.
Volume: 295
Issue: 5
Pages: E1065-75
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18311922 | J:133143
First Author: Turman MV
Year: 2008
Journal: Biochemistry
Title: Oxidative metabolism of a fatty acid amide hydrolase-regulated lipid, arachidonoyltaurine.
Volume: 47
Issue: 12
Pages: 3917-25
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32760397 | J:308218
 
First Author: Queck A
Year: 2020
Journal: Front Immunol
Title: Alox12/15 Deficiency Exacerbates, While Lipoxin A4 Ameliorates Hepatic Inflammation in Murine Alcoholic Hepatitis.
Volume: 11
Pages: 1447
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23079635 | J:194022
 
First Author: Chou VP
Year: 2013
Journal: Neuroscience
Title: Differential contribution of lipoxygenase isozymes to nigrostriatal vulnerability.
Volume: 228
Pages: 73-82
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18346986 | J:136092
First Author: Gubitosi-Klug RA
Year: 2008
Journal: Diabetes
Title: 5-Lipoxygenase, but not 12/15-lipoxygenase, contributes to degeneration of retinal capillaries in a mouse model of diabetic retinopathy.
Volume: 57
Issue: 5
Pages: 1387-93
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Publication
15328042 | J:92011
First Author: Emerson MR
Year: 2004
Journal: Brain Res
Title: Experimental allergic encephalomyelitis is exacerbated in mice deficient for 12/15-lipoxygenase or 5-lipoxygenase.
Volume: 1021
Issue: 1
Pages: 140-5
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22637477 | J:188859
First Author: Liu S
Year: 2012
Journal: J Biol Chem
Title: Smooth muscle-specific expression of calcium-independent phospholipase A2β (iPLA2β) participates in the initiation and early progression of vascular inflammation and neointima formation.
Volume: 287
Issue: 29
Pages: 24739-53
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19752233 | J:152766
First Author: Zarbock A
Year: 2009
Journal: J Immunol
Title: Improved survival and reduced vascular permeability by eliminating or blocking 12/15-lipoxygenase in mouse models of acute lung injury (ALI).
Volume: 183
Issue: 7
Pages: 4715-22
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19822654 | J:155469
First Author: Middleton MK
Year: 2009
Journal: Infect Immun
Title: 12/15-lipoxygenase-dependent myeloid production of interleukin-12 is essential for resistance to chronic toxoplasmosis.
Volume: 77
Issue: 12
Pages: 5690-700
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8944751 | J:36801
First Author: Funk CD
Year: 1996
Journal: Biochim Biophys Acta
Title: The molecular biology of mammalian lipoxygenases and the quest for eicosanoid functions using lipoxygenase-deficient mice.
Volume: 1304
Issue: 1
Pages: 65-84
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9518531 | J:46809
First Author: Krieg P
Year: 1998
Journal: Biochim Biophys Acta
Title: cDNA cloning of a 8-lipoxygenase and a novel epidermis-type lipoxygenase from phorbol ester-treated mouse skin.
Volume: 1391
Issue: 1
Pages: 7-12
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22279185 | J:184947
First Author: Rong S
Year: 2012
Journal: J Lipid Res
Title: Macrophage 12/15 lipoxygenase expression increases plasma and hepatic lipid levels and exacerbates atherosclerosis.
Volume: 53
Issue: 4
Pages: 686-95
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18296557 | J:135665
First Author: Wen Y
Year: 2008
Journal: Am J Physiol Heart Circ Physiol
Title: Role of 12/15-lipoxygenase in the expression of MCP-1 in mouse macrophages.
Volume: 294
Issue: 4
Pages: H1933-8
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30944221 | J:273825
First Author: Allen-Redpath K
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Phospholipid membranes drive abdominal aortic aneurysm development through stimulating coagulation factor activity.
Volume: 116
Issue: 16
Pages: 8038-8047
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15576842 | J:96696
First Author: Li SL
Year: 2005
Journal: J Lipid Res
Title: Effects of silencing leukocyte-type 12/15-lipoxygenase using short interfering RNAs.
Volume: 46
Issue: 2
Pages: 220-9
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22493235 | J:183845
First Author: Gregus AM
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Spinal 12-lipoxygenase-derived hepoxilin A3 contributes to inflammatory hyperalgesia via activation of TRPV1 and TRPA1 receptors.
Volume: 109
Issue: 17
Pages: 6721-6
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30855276 | J:289748
First Author: Han YH
Year: 2019
Journal: J Clin Invest
Title: A maresin 1/RORα/12-lipoxygenase autoregulatory circuit prevents inflammation and progression of nonalcoholic steatohepatitis.
Volume: 129
Issue: 4
Pages: 1684-1698
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25100742 | J:218330
First Author: Yeung J
Year: 2014
Journal: Blood
Title: Platelet 12-LOX is essential for FcγRIIa-mediated platelet activation.
Volume: 124
Issue: 14
Pages: 2271-9
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12122008 | J:79120
First Author: Zhao L
Year: 2002
Journal: J Biol Chem
Title: Selective interleukin-12 synthesis defect in 12/15-lipoxygenase-deficient macrophages associated with reduced atherosclerosis in a mouse model of familial hypercholesterolemia.
Volume: 277
Issue: 38
Pages: 35350-6
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36599368 | J:340014
First Author: Pernet E
Year: 2023
Journal: Nature
Title: Neonatal imprinting of alveolar macrophages via neutrophil-derived 12-HETE.
Volume: 614
Issue: 7948
Pages: 530-538
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25698732 | J:219863
First Author: Rudhard Y
Year: 2015
Journal: J Neurosci
Title: Identification of 12/15-lipoxygenase as a regulator of axon degeneration through high-content screening.
Volume: 35
Issue: 7
Pages: 2927-41
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19509298 | J:153174
First Author: Poeckel D
Year: 2009
Journal: J Biol Chem
Title: Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice.
Volume: 284
Issue: 31
Pages: 21077-89
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25313597 | J:264805
First Author: Brütsch SH
Year: 2015
Journal: Antioxid Redox Signal
Title: Expression of inactive glutathione peroxidase 4 leads to embryonic lethality, and inactivation of the Alox15 gene does not rescue such knock-in mice.
Volume: 22
Issue: 4
Pages: 281-93
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19633199 | J:152911
First Author: Stumpo DJ
Year: 2009
Journal: Blood
Title: Targeted disruption of Zfp36l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis.
Volume: 114
Issue: 12
Pages: 2401-10
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21307302 | J:171000
First Author: Sapieha P
Year: 2011
Journal: Sci Transl Med
Title: 5-Lipoxygenase metabolite 4-HDHA is a mediator of the antiangiogenic effect of ω-3 polyunsaturated fatty acids.
Volume: 3
Issue: 69
Pages: 69ra12
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16254318 | J:106033
First Author: Srivastava AK
Year: 2006
Journal: J Lipid Res
Title: Identification of quantitative trait loci that regulate obesity and serum lipid levels in MRL/MpJ x SJL/J inbred mice.
Volume: 47
Issue: 1
Pages: 123-33
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20947825 | J:184196
First Author: Deliri H
Year: 2011
Journal: Arterioscler Thromb Vasc Biol
Title: Increased 12/15-lipoxygenase enhances cell growth, fibronectin deposition, and neointimal formation in response to carotid injury.
Volume: 31
Issue: 1
Pages: 110-6
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31353262 | J:283668
First Author: Leiria LO
Year: 2019
Journal: Cell Metab
Title: 12-Lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat.
Volume: 30
Issue: 4
Pages: 768-783.e7
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19713213 | J:156345
First Author: Nagelin MH
Year: 2009
Journal: J Biol Chem
Title: Murine 12/15-lipoxygenase regulates ATP-binding cassette transporter G1 protein degradation through p38- and JNK2-dependent pathways.
Volume: 284
Issue: 45
Pages: 31303-14
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17873277 | J:128345
First Author: Nikolic DM
Year: 2007
Journal: J Biol Chem
Title: Class A scavenger receptor-mediated macrophage adhesion requires coupling of calcium-independent phospholipase A(2) and 12/15-lipoxygenase to Rac and Cdc42 activation.
Volume: 282
Issue: 46
Pages: 33405-11
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15781699 | J:98848
First Author: Lee GS
Year: 2005
Journal: Genetics
Title: A gene(s) for all-trans-retinoic acid-induced forelimb defects mapped and confirmed to murine chromosome 11.
Volume: 170
Issue: 1
Pages: 345-53
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36239312 | J:331053
 
First Author: Chandrasekaran P
Year: 2022
Journal: Development
Title: CXCL12 defines lung endothelial heterogeneity and promotes distal vascular growth.
Volume: 149
Issue: 21
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26438362 | J:229029
First Author: Yamamoto K
Year: 2015
Journal: J Exp Med
Title: The role of group IIF-secreted phospholipase A2 in epidermal homeostasis and hyperplasia.
Volume: 212
Issue: 11
Pages: 1901-19
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11130978 | J:66067
First Author: Lahbib-Mansais Y
Year: 2000
Journal: Mamm Genome
Title: Comparative mapping between humans and pigs: localization of 58 anchorage markers (TOASTs) by use of porcine somatic cell and radiation hybrid panels.
Volume: 11
Issue: 12
Pages: 1098-106
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12205107 | J:78525
First Author: Lemon WJ
Year: 2002
Journal: J Med Genet
Title: Identification of candidate lung cancer susceptibility genes in mouse using oligonucleotide arrays.
Volume: 39
Issue: 9
Pages: 644-55
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27689697 | J:235644
First Author: Wu Y
Year: 2016
Journal: PLoS Genet
Title: Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury.
Volume: 12
Issue: 9
Pages: e1006355
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12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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