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Search results 201 to 282 out of 282 for Alox12

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Type Details Score
Publication
22637477 | J:188859
First Author: Liu S
Year: 2012
Journal: J Biol Chem
Title: Smooth muscle-specific expression of calcium-independent phospholipase A2β (iPLA2β) participates in the initiation and early progression of vascular inflammation and neointima formation.
Volume: 287
Issue: 29
Pages: 24739-53
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Publication
19752233 | J:152766
First Author: Zarbock A
Year: 2009
Journal: J Immunol
Title: Improved survival and reduced vascular permeability by eliminating or blocking 12/15-lipoxygenase in mouse models of acute lung injury (ALI).
Volume: 183
Issue: 7
Pages: 4715-22
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Publication
19822654 | J:155469
First Author: Middleton MK
Year: 2009
Journal: Infect Immun
Title: 12/15-lipoxygenase-dependent myeloid production of interleukin-12 is essential for resistance to chronic toxoplasmosis.
Volume: 77
Issue: 12
Pages: 5690-700
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Publication
8944751 | J:36801
First Author: Funk CD
Year: 1996
Journal: Biochim Biophys Acta
Title: The molecular biology of mammalian lipoxygenases and the quest for eicosanoid functions using lipoxygenase-deficient mice.
Volume: 1304
Issue: 1
Pages: 65-84
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Publication
9518531 | J:46809
First Author: Krieg P
Year: 1998
Journal: Biochim Biophys Acta
Title: cDNA cloning of a 8-lipoxygenase and a novel epidermis-type lipoxygenase from phorbol ester-treated mouse skin.
Volume: 1391
Issue: 1
Pages: 7-12
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Publication
22279185 | J:184947
First Author: Rong S
Year: 2012
Journal: J Lipid Res
Title: Macrophage 12/15 lipoxygenase expression increases plasma and hepatic lipid levels and exacerbates atherosclerosis.
Volume: 53
Issue: 4
Pages: 686-95
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Publication
18296557 | J:135665
First Author: Wen Y
Year: 2008
Journal: Am J Physiol Heart Circ Physiol
Title: Role of 12/15-lipoxygenase in the expression of MCP-1 in mouse macrophages.
Volume: 294
Issue: 4
Pages: H1933-8
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Publication
30944221 | J:273825
First Author: Allen-Redpath K
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Phospholipid membranes drive abdominal aortic aneurysm development through stimulating coagulation factor activity.
Volume: 116
Issue: 16
Pages: 8038-8047
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Publication
15576842 | J:96696
First Author: Li SL
Year: 2005
Journal: J Lipid Res
Title: Effects of silencing leukocyte-type 12/15-lipoxygenase using short interfering RNAs.
Volume: 46
Issue: 2
Pages: 220-9
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Publication
22493235 | J:183845
First Author: Gregus AM
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Spinal 12-lipoxygenase-derived hepoxilin A3 contributes to inflammatory hyperalgesia via activation of TRPV1 and TRPA1 receptors.
Volume: 109
Issue: 17
Pages: 6721-6
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Publication
30855276 | J:289748
First Author: Han YH
Year: 2019
Journal: J Clin Invest
Title: A maresin 1/RORα/12-lipoxygenase autoregulatory circuit prevents inflammation and progression of nonalcoholic steatohepatitis.
Volume: 129
Issue: 4
Pages: 1684-1698
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Publication
25100742 | J:218330
First Author: Yeung J
Year: 2014
Journal: Blood
Title: Platelet 12-LOX is essential for FcγRIIa-mediated platelet activation.
Volume: 124
Issue: 14
Pages: 2271-9
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Publication
12122008 | J:79120
First Author: Zhao L
Year: 2002
Journal: J Biol Chem
Title: Selective interleukin-12 synthesis defect in 12/15-lipoxygenase-deficient macrophages associated with reduced atherosclerosis in a mouse model of familial hypercholesterolemia.
Volume: 277
Issue: 38
Pages: 35350-6
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Publication
36599368 | J:340014
First Author: Pernet E
Year: 2023
Journal: Nature
Title: Neonatal imprinting of alveolar macrophages via neutrophil-derived 12-HETE.
Volume: 614
Issue: 7948
Pages: 530-538
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Publication
25698732 | J:219863
First Author: Rudhard Y
Year: 2015
Journal: J Neurosci
Title: Identification of 12/15-lipoxygenase as a regulator of axon degeneration through high-content screening.
Volume: 35
Issue: 7
Pages: 2927-41
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Publication
19509298 | J:153174
First Author: Poeckel D
Year: 2009
Journal: J Biol Chem
Title: Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice.
Volume: 284
Issue: 31
Pages: 21077-89
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Publication
25313597 | J:264805
First Author: Brütsch SH
Year: 2015
Journal: Antioxid Redox Signal
Title: Expression of inactive glutathione peroxidase 4 leads to embryonic lethality, and inactivation of the Alox15 gene does not rescue such knock-in mice.
Volume: 22
Issue: 4
Pages: 281-93
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Publication
19633199 | J:152911
First Author: Stumpo DJ
Year: 2009
Journal: Blood
Title: Targeted disruption of Zfp36l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis.
Volume: 114
Issue: 12
Pages: 2401-10
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Publication
21307302 | J:171000
First Author: Sapieha P
Year: 2011
Journal: Sci Transl Med
Title: 5-Lipoxygenase metabolite 4-HDHA is a mediator of the antiangiogenic effect of ω-3 polyunsaturated fatty acids.
Volume: 3
Issue: 69
Pages: 69ra12
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Publication
16254318 | J:106033
First Author: Srivastava AK
Year: 2006
Journal: J Lipid Res
Title: Identification of quantitative trait loci that regulate obesity and serum lipid levels in MRL/MpJ x SJL/J inbred mice.
Volume: 47
Issue: 1
Pages: 123-33
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Publication
20947825 | J:184196
First Author: Deliri H
Year: 2011
Journal: Arterioscler Thromb Vasc Biol
Title: Increased 12/15-lipoxygenase enhances cell growth, fibronectin deposition, and neointimal formation in response to carotid injury.
Volume: 31
Issue: 1
Pages: 110-6
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Publication
31353262 | J:283668
First Author: Leiria LO
Year: 2019
Journal: Cell Metab
Title: 12-Lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat.
Volume: 30
Issue: 4
Pages: 768-783.e7
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Publication
19713213 | J:156345
First Author: Nagelin MH
Year: 2009
Journal: J Biol Chem
Title: Murine 12/15-lipoxygenase regulates ATP-binding cassette transporter G1 protein degradation through p38- and JNK2-dependent pathways.
Volume: 284
Issue: 45
Pages: 31303-14
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Publication
17873277 | J:128345
First Author: Nikolic DM
Year: 2007
Journal: J Biol Chem
Title: Class A scavenger receptor-mediated macrophage adhesion requires coupling of calcium-independent phospholipase A(2) and 12/15-lipoxygenase to Rac and Cdc42 activation.
Volume: 282
Issue: 46
Pages: 33405-11
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Publication
15781699 | J:98848
First Author: Lee GS
Year: 2005
Journal: Genetics
Title: A gene(s) for all-trans-retinoic acid-induced forelimb defects mapped and confirmed to murine chromosome 11.
Volume: 170
Issue: 1
Pages: 345-53
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Publication
36239312 | J:331053
 
First Author: Chandrasekaran P
Year: 2022
Journal: Development
Title: CXCL12 defines lung endothelial heterogeneity and promotes distal vascular growth.
Volume: 149
Issue: 21
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Publication
26438362 | J:229029
First Author: Yamamoto K
Year: 2015
Journal: J Exp Med
Title: The role of group IIF-secreted phospholipase A2 in epidermal homeostasis and hyperplasia.
Volume: 212
Issue: 11
Pages: 1901-19
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Publication
11130978 | J:66067
First Author: Lahbib-Mansais Y
Year: 2000
Journal: Mamm Genome
Title: Comparative mapping between humans and pigs: localization of 58 anchorage markers (TOASTs) by use of porcine somatic cell and radiation hybrid panels.
Volume: 11
Issue: 12
Pages: 1098-106
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Publication
12205107 | J:78525
First Author: Lemon WJ
Year: 2002
Journal: J Med Genet
Title: Identification of candidate lung cancer susceptibility genes in mouse using oligonucleotide arrays.
Volume: 39
Issue: 9
Pages: 644-55
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Publication
27689697 | J:235644
First Author: Wu Y
Year: 2016
Journal: PLoS Genet
Title: Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury.
Volume: 12
Issue: 9
Pages: e1006355
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 1
Description: Polyunsaturated fatty acid lipoxygenase ALOX12
Type: chain
End: 663
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Publication
35198058 | J:327756
First Author: Tak J
Year: 2022
Journal: Theranostics
Title: Gα12 overexpression in hepatocytes by ER stress exacerbates acute liver injury via ROCK1-mediated miR-15a and ALOX12 dysregulation.
Volume: 12
Issue: 4
Pages: 1570-1588
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Publication
7792391 | -
First Author: Hagmann W
Year: 1995
Journal: Prostaglandins
Title: 12-Lipoxygenase in Lewis lung carcinoma cells: molecular identity, intracellular distribution of activity and protein, and Ca(2+)-dependent translocation from cytosol to membranes.
Volume: 49
Issue: 1
Pages: 49-62
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Protein
P39655
Organism: Mus musculus/domesticus
Length: 663  
Fragment?: false
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Protein
Q8C587
Organism: Mus musculus/domesticus
Length: 390  
Fragment?: false
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Allele
Alox12<em1Smoc> | MGI:7288237
Name: arachidonate 12-lipoxygenase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Tg(SMN2-SMN1*Q282A)2Ahmb | MGI:6189119
Name: transgene insertion 2, Arthur H M Burghes
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Strain
MGI:6199466 | STOCK Grm7<Tg(SMN2)89Ahmb> Tg(SMN2-SMN1*Q282A)2Ahmb Smn1<tm1Msd>/J
Attribute String: targeted mutation, transgenic, mutant stock
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Strain
MGI:6189121 | FVB.Cg-Tg(SMN2*A111G)588Ahmb Tg(SMN2-SMN1*Q282A)2Ahmb Smn1<tm1Msd>/J
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Publication
28400162 | J:255424
First Author: Kutzner L
Year: 2017
Journal: Biochim Biophys Acta
Title: Mammalian ALOX15 orthologs exhibit pronounced dual positional specificity with docosahexaenoic acid.
Volume: 1862
Issue: 7
Pages: 666-675
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Publication
29982416 | J:265815
First Author: Iyer CC
Year: 2018
Journal: Hum Mol Genet
Title: Mild SMN missense alleles are only functional in the presence of SMN2 in mammals.
Volume: 27
Issue: 19
Pages: 3404-3416
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Publication
33084884 | J:301445
First Author: McGovern VL
Year: 2021
Journal: Hum Mol Genet
Title: Intragenic complementation of amino and carboxy terminal SMN missense mutations can rescue Smn null mice.
Volume: 29
Issue: 21
Pages: 3493-3503
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Publication
24076321 | J:210393
 
First Author: Gupta D
Year: 2013
Journal: Exp Eye Res
Title: Regulation of mouse lens maturation and gene expression by Krüppel-like factor 4.
Volume: 116
Pages: 205-18
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Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
11042159 | J:68323
First Author: Carninci P
Year: 2000
Journal: Genome Res
Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Volume: 10
Issue: 10
Pages: 1617-30
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Publication
10349636 | J:80645
 
First Author: Carninci P
Year: 1999
Journal: Methods Enzymol
Title: High-efficiency full-length cDNA cloning.
Volume: 303
Pages: 19-44
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Publication
11076861 | J:68324
First Author: Shibata K
Year: 2000
Journal: Genome Res
Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Volume: 10
Issue: 11
Pages: 1757-71
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Publication
16141073 | -
First Author: Katayama S
Year: 2005
Journal: Science
Title: Antisense transcription in the mammalian transcriptome.
Volume: 309
Issue: 5740
Pages: 1564-6
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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