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Search results 101 to 198 out of 198 for Ptpn23

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0.039s
Type Details Score
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1610515
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4399109
Age: embryonic day 9.5
Specimen Label: 2A
Detected: true
Specimen Num: 1
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610520
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4399109
Age: embryonic day 12.5
Specimen Label: 2B
Detected: true
Specimen Num: 2
GXD Expression        
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:4399109
Age: postnatal month 6
Specimen Label: Not shown
Detected: false
Specimen Num: 23
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3283428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4399109
Age: postnatal month 6
Specimen Label: Not shown
Detected: true
Specimen Num: 23
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3269128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4399109
Age: postnatal month 6
Specimen Label: 4D
Detected: true
Specimen Num: 18
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1720324
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4399109
Age: embryonic day 16.5
Specimen Label: 3F
Detected: true
Specimen Num: 12
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1720328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4399109
Age: postnatal month 6
Specimen Label: 4F
Detected: true
Specimen Num: 20
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3524628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4399109
Age: postnatal month 6
Specimen Label: 4E
Detected: true
Specimen Num: 19
GXD Expression
Probe: MGI:5285286
Assay Type: RNA in situ
Annotation Date: 2011-09-15
Strength: Present
Sex: Male
Emaps: EMAPS:3147628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5285448
Age: postnatal week 12
Image: 3A
Note: Expression is in cells located near the basement membrane of the seminiferous tubules.
Specimen Label: 3A
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5285286
Assay Type: RNA in situ
Annotation Date: 2011-09-15
Strength: Present
Sex: Male
Emaps: EMAPS:3148628
Pattern: Single cells
Stage: TS28
Assay Id: MGI:5285448
Age: postnatal week 12
Image: 3A
Note: Expression is in round spermatids, not in elongated spermatids.
Specimen Label: 3A
Detected: true
Specimen Num: 1
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3116915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4399109
Age: embryonic day 9.5
Specimen Label: 2A
Detected: true
Specimen Num: 1
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1767220
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4399109
Age: embryonic day 12.5
Specimen Label: 2C
Detected: true
Specimen Num: 3
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1624720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4399109
Age: embryonic day 12.5
Specimen Label: 2B
Detected: true
Specimen Num: 2
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1718520
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4399109
Age: embryonic day 12.5
Specimen Label: 2B
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3601720
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:4399109
Age: embryonic day 12.5
Note: Expression is in the endothelial layer.
Specimen Label: 2B
Detected: true
Specimen Num: 2
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286020
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4399109
Age: embryonic day 12.5
Specimen Label: 2B
Detected: true
Specimen Num: 2
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3286024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4399109
Age: embryonic day 16.5
Specimen Label: 3E
Detected: true
Specimen Num: 11
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1759724
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:4399109
Age: embryonic day 16.5
Note: Expression is on the internal side.
Specimen Label: 3A
Detected: true
Specimen Num: 7
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3522328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4399109
Age: postnatal month 6
Specimen Label: 4B
Detected: true
Specimen Num: 16
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750320
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4399109
Age: embryonic day 12.5
Specimen Label: 2B
Detected: true
Specimen Num: 2
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3274124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4399109
Age: embryonic day 16.5
Specimen Label: 3A
Detected: true
Specimen Num: 7
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1616415
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4399109
Age: embryonic day 9.5
Specimen Label: 2A
Detected: true
Specimen Num: 1
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1674720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4399109
Age: embryonic day 12.5
Specimen Label: 2F
Detected: true
Specimen Num: 6
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1877124
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:4399109
Age: embryonic day 16.5
Note: Expression is in the inner layer.
Specimen Label: 3H
Detected: true
Specimen Num: 14
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1666915
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:4399109
Age: embryonic day 9.5
Note: Expression is at the inner side.
Specimen Label: 2A
Detected: true
Specimen Num: 1
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1894128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4399109
Age: postnatal month 6
Specimen Label: 4H
Detected: true
Specimen Num: 22
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4399109
Age: embryonic day 16.5
Specimen Label: 3A
Detected: true
Specimen Num: 7
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1665615
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:4399109
Age: embryonic day 9.5
Note: Expression is in the ventricular layer.
Specimen Label: 2A
Detected: true
Specimen Num: 1
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1679724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4399109
Age: embryonic day 16.5
Specimen Label: 3A
Detected: true
Specimen Num: 7
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4399109
Age: postnatal month 6
Specimen Label: 4A
Detected: true
Specimen Num: 15
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3599820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4399109
Age: embryonic day 12.5
Specimen Label: 2D
Detected: true
Specimen Num: 4
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1897624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4399109
Age: embryonic day 16.5
Specimen Label: 3D
Detected: true
Specimen Num: 10
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1897628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4399109
Age: postnatal month 6
Specimen Label: 4C
Detected: true
Specimen Num: 17
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1685524
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4399109
Age: embryonic day 16.5
Specimen Label: 3E
Detected: true
Specimen Num: 11
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1685528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4399109
Age: postnatal month 6
Specimen Label: Not shown
Detected: true
Specimen Num: 23
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1611715
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4399109
Age: embryonic day 9.5
Specimen Label: 2A
Detected: true
Specimen Num: 1
GXD Expression        
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2823928
Stage: TS28
Assay Id: MGI:4399109
Age: postnatal month 6
Specimen Label: 4C
Detected: false
Specimen Num: 17
GXD Expression        
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:4399109
Age: postnatal month 6
Specimen Label: Not shown
Detected: false
Specimen Num: 23
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4399109
Age: embryonic day 12.5
Specimen Label: 2B
Detected: true
Specimen Num: 2
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4399109
Age: embryonic day 16.5
Specimen Label: 3H
Detected: true
Specimen Num: 14
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:4399109
Age: embryonic day 12.5
Note: Expression is in the diaphragm.
Specimen Label: 2B
Detected: true
Specimen Num: 2
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4399109
Age: embryonic day 12.5
Specimen Label: 2B
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757724
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:4399109
Age: embryonic day 16.5
Note: Expression is in the ventral side, absent at the dorsal side.
Specimen Label: 3A
Detected: true
Specimen Num: 7
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757724
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:4399109
Age: embryonic day 16.5
Note: Expression is in the ventral side, absent at the dorsal side.
Specimen Label: 3B
Detected: true
Specimen Num: 8
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1738320
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4399109
Age: embryonic day 12.5
Specimen Label: 2F
Detected: true
Specimen Num: 6
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1654015
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:4399109
Age: embryonic day 9.5
Note: Expression is at the inner side.
Specimen Label: 2A
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3521728
Pattern: Non-Uniform
Stage: TS28
Assay Id: MGI:4399109
Age: postnatal month 6
Note: Uniform and faint staining throughout with some strong staining cells.
Specimen Label: 4B
Detected: true
Specimen Num: 16
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1768020
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:4399109
Age: embryonic day 12.5
Note: Expression is in the cartilage primordium of the clivus.
Specimen Label: 2B
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-12-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1881224
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:4399109
Age: embryonic day 16.5
Note: Expression is in the acini and ducts.
Specimen Label: 3G
Detected: true
Specimen Num: 13
Publication
First Author: Harkiolaki M
Year: 2009
Journal: Structure
Title: Distinct binding modes of two epitopes in Gab2 that interact with the SH3C domain of Grb2.
Volume: 17
Issue: 6
Pages: 809-22
Publication
First Author: Tanaka K
Year: 2002
Journal: Dev Biol
Title: Spermatogonia-dependent expression of testicular genes in mice.
Volume: 246
Issue: 2
Pages: 466-79
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: Mammalian Functional Genomics Centre
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Interaction Experiment
Description: PTPN23 binds the dynein adaptor BICD1 and is required for endocytic sorting of neurotrophin receptors.
Allele
Name: protein tyrosine phosphatase, non-receptor type 23; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Publication
First Author: Baietti MF
Year: 2012
Journal: Nat Cell Biol
Title: Syndecan-syntenin-ALIX regulates the biogenesis of exosomes.
Volume: 14
Issue: 7
Pages: 677-85
Publication
First Author: Odorizzi G
Year: 2003
Journal: J Cell Sci
Title: Bro1 is an endosome-associated protein that functions in the MVB pathway in Saccharomyces cerevisiae.
Volume: 116
Issue: Pt 10
Pages: 1893-903
Publication
First Author: Luhtala N
Year: 2004
Journal: J Cell Biol
Title: Bro1 coordinates deubiquitination in the multivesicular body pathway by recruiting Doa4 to endosomes.
Volume: 166
Issue: 5
Pages: 717-29
Protein Domain
Type: Family
Description: This entry represents a group of vacuolar-sorting proteins, including Bro1 from yeasts, PTPN23/PDCD6IP (or ALIX) from humans and Rim20 from Yarrowia lipolytica. Bro1 is an endosome-associated protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles []. It acts as an adapter that recruits the DOA4 deubiquitinase to the endosomes, leading to deubiquitination of cargo proteins prior to the lumenal sequestration []. PTPN23 has been shown to direct the molecular sorting of several transmembrane receptors, such as epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor (PDGFR) in non-neuronal cells and neurotrophin receptor in neuronal cells []. ALIX, together with syndecan and syntenin, regulates the biogenesis of exosomes [].
Publication
First Author: Zhang S
Year: 2017
Journal: Genes Dev
Title: Suppression of protein tyrosine phosphatase N23 predisposes to breast tumorigenesis via activation of FYN kinase.
Volume: 31
Issue: 19
Pages: 1939-1957
Publication
First Author: Gosney JA
Year: 2018
Journal: J Biol Chem
Title: Proteomics reveals novel protein associations with early endosomes in an epidermal growth factor-dependent manner.
Volume: 293
Issue: 16
Pages: 5895-5908
Protein
Organism: Mus musculus/domesticus
Length: 869  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 909  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 872  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1692  
Fragment?: false