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Search results 201 to 300 out of 307 for Mbd3

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Type Details Score
Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Strain
MGI:6121778 | B6.129P2-Mbd3<tm2Bh>/H
Attribute String: mutant strain, congenic, targeted mutation
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Protein
Q9Z2D8-2
Organism: Mus musculus/domesticus
Length: 253  
Fragment?: false
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Interaction Experiment
Datta J (2005)
Description: Physical and functional interaction of DNA methyltransferase 3A with Mbd3 and Brg1 in mouse lymphosarcoma cells.
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Interaction Experiment
Kaji K (2006)
Description: The NuRD component Mbd3 is required for pluripotency of embryonic stem cells.
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Protein
Q9DA79
Organism: Mus musculus/domesticus
Length: 493  
Fragment?: false
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Allele
Mbd3<tm1Smoc> | MGI:7290992
Name: methyl-CpG binding domain protein 3; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Strain
MGI:6355010 | C57BL/6J-Mbd3<tm1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, targeted mutation
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Publication
16246164 | J:103658
First Author: Berger J
Year: 2005
Journal: Biochem Soc Trans
Title: Role of MBD2 in gene regulation and tumorigenesis.
Volume: 33
Issue: Pt 6
Pages: 1537-40
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Publication
17694084 | -
First Author: Denslow SA
Year: 2007
Journal: Oncogene
Title: The human Mi-2/NuRD complex and gene regulation.
Volume: 26
Issue: 37
Pages: 5433-8
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Protein Domain
IPR025884 | MeCpG-bd_2/3_C_dom
Type: Domain
Description: CpG-methylation is a frequently occurring epigenetic modification of vertebrate genomes resulting in transcriptional repression. This domain is found at the C terminus of the methyl-CpG-binding domain (MBD) containing proteins MBD2 []and MBD3 []. The latter was shown to not bind directly to methyl-CpG DNA but rather interact with components of the NuRD/Mi2 complex [], an abundant deacetylase complex.
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Allele
Mbd3<tm2Bh> | MGI:4887391
Name: methyl-CpG binding domain protein 3; targeted mutation 2, Brian Hendrich
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Protein
Q9D9H3
Organism: Mus musculus/domesticus
Length: 186  
Fragment?: false
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Protein
Q3UXB0
Organism: Mus musculus/domesticus
Length: 228  
Fragment?: false
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Protein
Q0P5Y0
Organism: Mus musculus/domesticus
Length: 186  
Fragment?: false
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Protein
Q8K591
Organism: Mus musculus/domesticus
Length: 228  
Fragment?: false
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Protein
Q6P237
Organism: Mus musculus/domesticus
Length: 228  
Fragment?: false
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Publication
30228260 | J:319689
First Author: Zhang T
Year: 2018
Journal: Nat Commun
Title: A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes.
Volume: 9
Issue: 1
Pages: 3798
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Publication
18942147 | J:140708
First Author: Jin SG
Year: 2008
Journal: Dev Dyn
Title: Haploid male germ cell- and oocyte-specific Mbd3l1 and Mbd3l2 genes are dispensable for early development, fertility, and zygotic DNA demethylation in the mouse.
Volume: 237
Issue: 11
Pages: 3435-43
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Publication
23670560 | J:199719
First Author: Kolar SS
Year: 2013
Journal: Infect Immun
Title: Protective role of murine β-defensins 3 and 4 and cathelin-related antimicrobial peptide in Fusarium solani keratitis.
Volume: 81
Issue: 8
Pages: 2669-77
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Genotype
Genotype
Symbol: Mbd3/Mbd3 Tg(Vil1-cre)20Syr/?
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mbd3/Mbd3 Tg(Nes-cre)1Kln/?
Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Publication
12504854 | J:80802
First Author: Jiang CL
Year: 2002
Journal: Genomics
Title: MBD3L1 and MBD3L2, two new proteins homologous to the methyl-CpG-binding proteins MBD2 and MBD3: characterization of MBD3L1 as a testis-specific transcriptional repressor.
Volume: 80
Issue: 6
Pages: 621-9
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Publication
15456747 | J:95173
First Author: Jiang CL
Year: 2004
Journal: J Biol Chem
Title: MBD3L1 is a transcriptional repressor that interacts with methyl-CpG-binding protein 2 (MBD2) and components of the NuRD complex.
Volume: 279
Issue: 50
Pages: 52456-64
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Publication
22158038 | J:196550
First Author: Rusiniak ME
Year: 2012
Journal: Oncogene
Title: Mcm2 deficiency results in short deletions allowing high resolution identification of genes contributing to lymphoblastic lymphoma.
Volume: 31
Issue: 36
Pages: 4034-44
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Publication
21796152 | J:182180
First Author: Rodriguez-Martin M
Year: 2011
Journal: J Invest Dermatol
Title: Expression of epidermal CAMP changes in parallel with permeability barrier status.
Volume: 131
Issue: 11
Pages: 2263-70
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Publication
17943185 | J:135506
First Author: Aberg KM
Year: 2008
Journal: J Invest Dermatol
Title: Co-regulation and interdependence of the mammalian epidermal permeability and antimicrobial barriers.
Volume: 128
Issue: 4
Pages: 917-25
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Publication
19933858 | J:157484
First Author: Wu M
Year: 2009
Journal: J Immunol
Title: Beta-defensins 2 and 3 together promote resistance to Pseudomonas aeruginosa keratitis.
Volume: 183
Issue: 12
Pages: 8054-60
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Publication
29547954 | J:263726
First Author: Kim MY
Year: 2018
Journal: Nucleic Acids Res
Title: Mbd2-CP2c loop drives adult-type globin gene expression and definitive erythropoiesis.
Volume: 46
Issue: 10
Pages: 4933-4949
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Protein
Q9Z2E1
Organism: Mus musculus/domesticus
Length: 414  
Fragment?: false
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Publication
12529184 | -
First Author: Roloff TC
Year: 2003
Journal: BMC Genomics
Title: Comparative study of methyl-CpG-binding domain proteins.
Volume: 4
Issue: 1
Pages: 1
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Protein Domain
IPR001739 | Methyl_CpG_DNA-bd
Type: Domain
Description: Methylation at CpG dinucleotide, the most common DNA modification ineukaryotes, has been correlated with gene silencing associated with variousphenomena such as genomic imprinting, transposon and chromosome X inactivation, differentiation, and cancer. Effects of DNA methylation are mediated through proteins which bind to symmetrically methylated CpGs. Such proteins contain a specific domain of ~70 residues, the methyl-CpG-binding domain (MBD), which is linked to additional domains associated with chromatin, such as the bromodomain, the AT hook motif,the SET domain, or the PHD finger. MBD-containing proteins appear to act as structural proteins, which recruit a variety of histone deacetylase (HDAC) complexes and chromatin remodelling factors, leading to chromatin compaction and, consequently, to transcriptional repression. The MBD of MeCP2, MBD1, MBD2, MBD4 and BAZ2 mediates binding to DNA, in case of MeCP2, MBD1 and MBD2 preferentially to methylated CpG. In case of human MBD3 and SETDB1 the MBD has been shown to mediate protein-protein interactions [, ].The MBD folds into an alpha/beta sandwich structure comprising a layer oftwisted beta sheet, backed by another layer formed by the alpha1 helix and ahairpin loop at the C terminus. These layers are both amphipathic, with the alpha1 helix and the beta sheet lying parallel and the hydrophobic faces tightly packed against each other. The beta sheet is composed of two long inner strands (beta2 and beta3) sandwiched by two shorter outer strands (beta1 and beta4) [].
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Publication
26332373 | J:227227
First Author: Gowda RN
Year: 2015
Journal: PLoS One
Title: Functions of Peptidoglycan Recognition Proteins (Pglyrps) at the Ocular Surface: Bacterial Keratitis in Gene-Targeted Mice Deficient in Pglyrp-2, -3 and -4.
Volume: 10
Issue: 9
Pages: e0137129
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Protein
B1AYB6
Organism: Mus musculus/domesticus
Length: 1498  
Fragment?: false
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Protein
Q3TU27
Organism: Mus musculus/domesticus
Length: 365  
Fragment?: false
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Protein
Q69ZJ2
Organism: Mus musculus/domesticus
Length: 1753  
Fragment?: true
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Protein
A0A0N4SWA0
Organism: Mus musculus/domesticus
Length: 386  
Fragment?: false
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Protein
Q3UG18
Organism: Mus musculus/domesticus
Length: 386  
Fragment?: false
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Protein
B4XVP4
Organism: Mus musculus/domesticus
Length: 241  
Fragment?: false
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Protein
B1AYB5
Organism: Mus musculus/domesticus
Length: 1728  
Fragment?: false
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Protein
Q8BUR7
Organism: Mus musculus/domesticus
Length: 102  
Fragment?: true
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Protein
Q9Z2D6
Organism: Mus musculus/domesticus
Length: 484  
Fragment?: false
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Protein
Q3TY92
Organism: Mus musculus/domesticus
Length: 1003  
Fragment?: false
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Protein
D3YY81
Organism: Mus musculus/domesticus
Length: 172  
Fragment?: false
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Protein
D3YV97
Organism: Mus musculus/domesticus
Length: 130  
Fragment?: true
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Protein
Q8BRP6
Organism: Mus musculus/domesticus
Length: 181  
Fragment?: true
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Protein
D3Z7U4
Organism: Mus musculus/domesticus
Length: 189  
Fragment?: false
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Protein
Q3V0H2
Organism: Mus musculus/domesticus
Length: 764  
Fragment?: true
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Protein
B1AYB7
Organism: Mus musculus/domesticus
Length: 856  
Fragment?: false
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Protein
E9Q572
Organism: Mus musculus/domesticus
Length: 1005  
Fragment?: false
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Protein
A0A1W2P6L0
Organism: Mus musculus/domesticus
Length: 763  
Fragment?: true
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Protein
Q8CGH2
Organism: Mus musculus/domesticus
Length: 769  
Fragment?: true
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Protein
Q05CX2
Organism: Mus musculus/domesticus
Length: 706  
Fragment?: true
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Protein
Q80VL8
Organism: Mus musculus/domesticus
Length: 709  
Fragment?: true
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Publication
12787239 | -
First Author: Zemach A
Year: 2003
Journal: Plant J
Title: Characterization of Arabidopsis thaliana methyl-CpG-binding domain (MBD) proteins.
Volume: 34
Issue: 5
Pages: 565-72
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Protein
Q9Z2E2
Organism: Mus musculus/domesticus
Length: 636  
Fragment?: false
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Protein
Q9Z2D7
Organism: Mus musculus/domesticus
Length: 554  
Fragment?: false
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Protein
A0A286YDI1
Organism: Mus musculus/domesticus
Length: 644  
Fragment?: false
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Protein
A0A0R4J159
Organism: Mus musculus/domesticus
Length: 588  
Fragment?: false
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Protein
A0A5F8MPN9
Organism: Mus musculus/domesticus
Length: 613  
Fragment?: false
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Protein
Q69ZI8
Organism: Mus musculus/domesticus
Length: 1369  
Fragment?: true
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Protein
A0A0R4J0A8
Organism: Mus musculus/domesticus
Length: 554  
Fragment?: false
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Protein
Q3TRE4
Organism: Mus musculus/domesticus
Length: 298  
Fragment?: false
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Protein
Q8C267
Organism: Mus musculus/domesticus
Length: 713  
Fragment?: false
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Protein
B2RXP3
Organism: Mus musculus/domesticus
Length: 697  
Fragment?: false
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Protein
B4XVN8
Organism: Mus musculus/domesticus
Length: 697  
Fragment?: false
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Protein
B4XVP0
Organism: Mus musculus/domesticus
Length: 675  
Fragment?: false
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Protein
B4XVP8
Organism: Mus musculus/domesticus
Length: 503  
Fragment?: false
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Protein
B4XVN9
Organism: Mus musculus/domesticus
Length: 697  
Fragment?: false
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Protein
B4XVP5
Organism: Mus musculus/domesticus
Length: 525  
Fragment?: false
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Protein
B4XVN7
Organism: Mus musculus/domesticus
Length: 697  
Fragment?: false
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Protein
B4XVP1
Organism: Mus musculus/domesticus
Length: 675  
Fragment?: false
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Protein
Q91YE5
Organism: Mus musculus/domesticus
Length: 1889  
Fragment?: false
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Protein
A2AUY4
Organism: Mus musculus/domesticus
Length: 2123  
Fragment?: false
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Protein
O88974
Organism: Mus musculus/domesticus
Length: 1307  
Fragment?: false
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Protein
E9Q374
Organism: Mus musculus/domesticus
Length: 1888  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom