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Search results 1 to 100 out of 543 for Hnf1a

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0.051s
Type Details Score
Gene
Type: gene
Organism: Not Specified
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Publication
First Author: Kalisz M
Year: 2020
Journal: EMBO J
Title: HNF1A recruits KDM6A to activate differentiated acinar cell programs that suppress pancreatic cancer.
Volume: 39
Issue: 9
Pages: e102808
Publication  
First Author: Song H
Year: 2023
Journal: JCI Insight
Title: High-fat diet plus HNF1A variant promotes polyps by activating β-catenin in early-onset colorectal cancer.
Volume: 8
Issue: 13
Publication
First Author: Beucher A
Year: 2022
Journal: Nat Cell Biol
Title: The HASTER lncRNA promoter is a cis-acting transcriptional stabilizer of HNF1A.
Volume: 24
Issue: 10
Pages: 1528-1540
Publication
First Author: Shih DQ
Year: 2001
Journal: Diabetes
Title: Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism.
Volume: 50
Issue: 11
Pages: 2472-80
Publication
First Author: von Wnuck Lipinski K
Year: 2017
Journal: Blood
Title: Hepatocyte nuclear factor 1A deficiency causes hemolytic anemia in mice by altering erythrocyte sphingolipid homeostasis.
Volume: 130
Issue: 25
Pages: 2786-2798
Publication
First Author: Servitja JM
Year: 2009
Journal: Mol Cell Biol
Title: Hnf1alpha (MODY3) controls tissue-specific transcriptional programs and exerts opposed effects on cell growth in pancreatic islets and liver.
Volume: 29
Issue: 11
Pages: 2945-59
Publication
First Author: Bonzo JA
Year: 2010
Journal: Mol Endocrinol
Title: Metabolomics identifies novel Hnf1alpha-dependent physiological pathways in vivo.
Volume: 24
Issue: 12
Pages: 2343-55
Publication
First Author: Brial F
Year: 2015
Journal: Diabetes
Title: Ghrelin Inhibition Restores Glucose Homeostasis in Hepatocyte Nuclear Factor-1α (MODY3)-Deficient Mice.
Volume: 64
Issue: 9
Pages: 3314-20
Publication
First Author: D'Angelo A
Year: 2010
Journal: Development
Title: Hepatocyte nuclear factor 1alpha and beta control terminal differentiation and cell fate commitment in the gut epithelium.
Volume: 137
Issue: 9
Pages: 1573-82
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Lee YH
Year: 1998
Journal: Mol Cell Biol
Title: Laron dwarfism and non-insulin-dependent diabetes mellitus in the Hnf-1alpha knockout mouse.
Volume: 18
Issue: 5
Pages: 3059-68
Publication
First Author: Rose RB
Year: 2000
Journal: Biochemistry
Title: High-resolution structure of the HNF-1alpha dimerization domain.
Volume: 39
Issue: 49
Pages: 15062-70
Publication
First Author: Fukui K
Year: 2005
Journal: Cell Metab
Title: The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formation.
Volume: 2
Issue: 6
Pages: 373-84
Publication
First Author: Yamagata K
Year: 2002
Journal: Diabetes
Title: Overexpression of dominant-negative mutant hepatocyte nuclear fctor-1 alpha in pancreatic beta-cells causes abnormal islet architecture with decreased expression of E-cadherin, reduced beta-cell proliferation, and diabetes.
Volume: 51
Issue: 1
Pages: 114-23
Publication
First Author: Pontoglio M
Year: 1998
Journal: J Clin Invest
Title: Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice.
Volume: 101
Issue: 10
Pages: 2215-22
Publication
First Author: Pontoglio M
Year: 2001
Journal: J Exp Med
Title: Hepatocyte nuclear factor 1alpha controls the expression of terminal complement genes.
Volume: 194
Issue: 11
Pages: 1683-9
Publication
First Author: Anderson AL
Year: 2005
Journal: J Virol
Title: Alpha/beta interferon differentially modulates the clearance of cytoplasmic encapsidated replication intermediates and nuclear covalently closed circular hepatitis B virus (HBV) DNA from the livers of hepatocyte nuclear factor 1alpha-null HBV transgenic mice.
Volume: 79
Issue: 17
Pages: 11045-52
Publication
First Author: Lee YH
Year: 2003
Journal: Mol Cell Biol
Title: Liver-specific reactivation of the inactivated Hnf-1alpha gene: elimination of liver dysfunction to establish a mouse MODY3 model.
Volume: 23
Issue: 3
Pages: 923-32
Publication
First Author: Bosse T
Year: 2006
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Hepatocyte nuclear factor-1alpha is required for expression but dispensable for histone acetylation of the lactase-phlorizin hydrolase gene in vivo.
Volume: 290
Issue: 5
Pages: G1016-24
Publication
First Author: Luco RF
Year: 2008
Journal: PLoS Genet
Title: Targeted deficiency of the transcriptional activator Hnf1alpha alters subnuclear positioning of its genomic targets.
Volume: 4
Issue: 5
Pages: e1000079
Publication
First Author: Cheung C
Year: 2003
Journal: Biochem Pharmacol
Title: Hepatic expression of cytochrome P450s in hepatocyte nuclear factor 1-alpha (HNF1alpha)-deficient mice.
Volume: 66
Issue: 10
Pages: 2011-20
Publication
First Author: Dukes ID
Year: 1998
Journal: J Biol Chem
Title: Defective pancreatic beta-cell glycolytic signaling in hepatocyte nuclear factor-1alpha-deficient mice.
Volume: 273
Issue: 38
Pages: 24457-64
Publication
First Author: Akiyama TE
Year: 2000
Journal: J Biol Chem
Title: Regulation of the liver fatty acid-binding protein gene by hepatocyte nuclear factor 1alpha (HNF1alpha). Alterations in fatty acid homeostasis in HNF1alpha-deficient mice.
Volume: 275
Issue: 35
Pages: 27117-22
Publication
First Author: Luco RF
Year: 2006
Journal: Diabetes
Title: A conditional model reveals that induction of hepatocyte nuclear factor-1alpha in Hnf1alpha-null mutant beta-cells can activate silenced genes postnatally, whereas overexpression is deleterious.
Volume: 55
Issue: 8
Pages: 2202-11
Publication  
First Author: Boileau P
Year: 2002
Journal: Diabetes
Title: Decreased glibenclamide uptake in hepatocytes of hepatocyte nuclear factor-1alpha-deficient mice: a mechanism for hypersensitivity to sulfonylurea therapy in patients with maturity-onset diabetes of the young, type 3 (MODY3).
Volume: 51 Suppl 3
Pages: S343-8
Publication
First Author: Ni Q
Year: 2017
Journal: FEBS Lett
Title: Deletion of HNF1α in hepatocytes results in fatty liver-related hepatocellular carcinoma in mice.
Volume: 591
Issue: 13
Pages: 1947-1957
Publication
First Author: Chu Y
Year: 2023
Journal: Diabetes
Title: Lysine 117 Residue Is Essential for the Function of the Hepatocyte Nuclear Factor 1α.
Volume: 72
Issue: 10
Pages: 1502-1516
Publication
First Author: Mostofa MG
Year: 2022
Journal: J Biol Chem
Title: MicroRNA-200c coordinates HNF1 homeobox B and apolipoprotein O functions to modulate lipid homeostasis in alcoholic fatty liver disease.
Volume: 298
Issue: 6
Pages: 101966
Publication
First Author: Malakauskas SM
Year: 2009
Journal: Mol Endocrinol
Title: Increased insulin sensitivity in mice lacking collectrin, a downstream target of HNF-1alpha.
Volume: 23
Issue: 6
Pages: 881-92
Publication
First Author: Miura N
Year: 1993
Journal: Eur J Cell Biol
Title: Immunological characterization of hepatocyte nuclear factor 1 protein: appearance of hepatocyte nuclear factor 1 protein in developing mouse embryos.
Volume: 60
Issue: 2
Pages: 376-82
Publication
First Author: Vandromme M
Year: 1996
Journal: Trends Biochem Sci
Title: Regulation of transcription factor localization: fine-tuning of gene expression.
Volume: 21
Issue: 2
Pages: 59-64
Publication
First Author: Yamagata K
Year: 1996
Journal: Nature
Title: Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)
Volume: 384
Issue: 6608
Pages: 455-8
Publication
First Author: Jakowlew SB
Year: 1998
Journal: Mol Carcinog
Title: Reduction in transforming growth factor-beta type II receptor in mouse lung carcinogenesis.
Volume: 22
Issue: 1
Pages: 46-56
Publication  
First Author: Winzell MS
Year: 2004
Journal: Diabetes
Title: Beta-cell-targeted expression of a dominant-negative mutant of hepatocyte nuclear factor-1alpha in mice: diabetes model with beta-cell dysfunction partially rescued by nonglucose secretagogues.
Volume: 53 Suppl 3
Pages: S92-6
Publication
First Author: Watanabe T
Year: 2020
Journal: Sci Rep
Title: Transcriptional Regulation of the Angptl8 Gene by Hepatocyte Nuclear Factor-1 in the Murine Liver.
Volume: 10
Issue: 1
Pages: 9999
GXD Expression    
Probe: MGI:3799860
Assay Type: RT-PCR
Annotation Date: 2008-08-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1636317
Stage: TS17
Assay Id: MGI:3800272
Age: embryonic day 10.5
Image: 2
Specimen Label: 10.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5289194
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289431
Age: embryonic day 2.0
Specimen Label: 4-cell-A1-1
Detected: false
Specimen Num: 13
GXD Expression      
Probe: MGI:5289194
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289431
Age: embryonic day 2.0
Specimen Label: 4-cell-A1-2
Detected: false
Specimen Num: 14
GXD Expression      
Probe: MGI:5289194
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289431
Age: embryonic day 2.0
Specimen Label: 4-cell-A2-1
Detected: false
Specimen Num: 15
GXD Expression      
Probe: MGI:5289194
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289431
Age: embryonic day 2.0
Specimen Label: 4-cell-A2-2
Detected: false
Specimen Num: 16
GXD Expression      
Probe: MGI:5289194
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289431
Age: embryonic day 2.0
Specimen Label: 4-cell-A3-1
Detected: false
Specimen Num: 17
GXD Expression      
Probe: MGI:5289194
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289431
Age: embryonic day 2.0
Specimen Label: 4-cell-A3-2
Detected: false
Specimen Num: 18
GXD Expression      
Probe: MGI:5289194
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289431
Age: embryonic day 2.0
Specimen Label: 4-cell-A4-1
Detected: false
Specimen Num: 19
GXD Expression      
Probe: MGI:5289194
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289431
Age: embryonic day 2.0
Specimen Label: 4-cell-A4-2
Detected: false
Specimen Num: 20
GXD Expression      
Probe: MGI:5289194
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289431
Age: embryonic day 2.0
Specimen Label: 4-cell-B1-1
Detected: false
Specimen Num: 21
GXD Expression      
Probe: MGI:5289194
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289431
Age: embryonic day 2.0
Specimen Label: 4-cell-B1-2
Detected: false
Specimen Num: 22
GXD Expression      
Probe: MGI:5289194
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289431
Age: embryonic day 2.0
Specimen Label: 4-cell-B2-1
Detected: false
Specimen Num: 23
GXD Expression      
Probe: MGI:5289194
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289431
Age: embryonic day 2.0
Specimen Label: 4-cell-B2-2
Detected: false
Specimen Num: 24
GXD Expression      
Probe: MGI:5289194
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289431
Age: embryonic day 2.0
Specimen Label: 4-cell-B3-1
Detected: false
Specimen Num: 25
GXD Expression      
Probe: MGI:5289194
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289431
Age: embryonic day 2.0
Specimen Label: 4-cell-B3-2
Detected: false
Specimen Num: 26
GXD Expression      
Probe: MGI:5289194
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289431
Age: embryonic day 2.0
Specimen Label: 4-cell-B4-1
Detected: false
Specimen Num: 27
GXD Expression      
Probe: MGI:5289194
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289431
Age: embryonic day 2.0
Specimen Label: 4-cell-B4-2
Detected: false
Specimen Num: 28
GXD Expression      
Probe: MGI:5289194
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289431
Age: embryonic day 2.0
Specimen Label: 4-cell-C1-1
Detected: false
Specimen Num: 29
GXD Expression      
Probe: MGI:5289194
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289431
Age: embryonic day 2.0
Specimen Label: 4-cell-C1-2
Detected: false
Specimen Num: 30
GXD Expression      
Probe: MGI:5289194
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289431
Age: embryonic day 2.0
Specimen Label: 4-cell-C2-1
Detected: false
Specimen Num: 31
GXD Expression      
Probe: MGI:5289194
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289431
Age: embryonic day 2.0
Specimen Label: 4-cell-C2-2
Detected: false
Specimen Num: 32
GXD Expression      
Probe: MGI:5289194
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289431
Age: embryonic day 2.0
Specimen Label: 4-cell-C3-1
Detected: false
Specimen Num: 33
GXD Expression      
Probe: MGI:5289194
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289431
Age: embryonic day 2.0
Specimen Label: 4-cell-C3-2
Detected: false
Specimen Num: 34
GXD Expression      
Probe: MGI:5289194
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289431
Age: embryonic day 2.0
Specimen Label: 4-cell-C4-1
Detected: false
Specimen Num: 35
GXD Expression      
Probe: MGI:5289194
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289431
Age: embryonic day 2.0
Specimen Label: 4-cell-C4-2
Detected: false
Specimen Num: 36
GXD Expression      
Probe: MGI:3815796
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:160415
Stage: TS05
Assay Id: MGI:3816600
Age: embryonic day 4.5
Specimen Label: E4.5 inner cell mass
Detected: false
Specimen Num: 8
GXD Expression      
Probe: MGI:2655956
Assay Type: RNase protection
Annotation Date: 2003-04-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3526928
Stage: TS28
Assay Id: MGI:2655970
Age: embryonic day 6.5
Specimen Label: 6.5 dd.
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:2655956
Assay Type: RNase protection
Annotation Date: 2003-04-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3526928
Stage: TS28
Assay Id: MGI:2655970
Age: embryonic day 8.5
Specimen Label: 8.5 dd.
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:2655956
Assay Type: RNase protection
Annotation Date: 2003-04-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3526928
Stage: TS28
Assay Id: MGI:2655970
Age: embryonic day 9.5
Specimen Label: 9.5 dd.
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2655956
Assay Type: RNase protection
Annotation Date: 2003-04-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3526928
Stage: TS28
Assay Id: MGI:2655970
Age: embryonic day 7.5
Specimen Label: 7.5 dd.
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:3513173
Assay Type: RT-PCR
Annotation Date: 2005-01-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1631915
Stage: TS15
Assay Id: MGI:3513202
Age: embryonic day 9.5
Specimen Label: E d9.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3815796
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3816600
Age: embryonic day 1.5
Specimen Label: 2-cell embryo
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:3815796
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:3816600
Age: embryonic day 2.0
Specimen Label: 4-cell embryo
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:7284285
Assay Type: RT-PCR
Annotation Date: 2022-06-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608515
Stage: TS15
Assay Id: MGI:7284320
Age: embryonic day 9.5
Specimen Label: +/-
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7284285
Assay Type: RT-PCR
Annotation Date: 2022-06-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608515
Stage: TS15
Assay Id: MGI:7284320
Age: embryonic day 9.5
Specimen Label: +/+
Detected: true
Specimen Num: 2