Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:7315042 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-07-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3747123 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:7316406 |
Age: |
embryonic day 15.5 |
|
Note: |
Expression is reduced in this mutant compared to controls. |
Specimen Label: |
1O' |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7315042 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-07-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3747123 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:7316406 |
Age: |
embryonic day 15.5 |
|
Note: |
Expression is in the ventricular and subventricular zone. |
Specimen Label: |
1O |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7315042 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-07-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3746923 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:7316406 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
1P |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7315042 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-07-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3746923 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:7316406 |
Age: |
embryonic day 15.5 |
|
Note: |
Expression is reduced in this mutant compared to controls. |
Specimen Label: |
1P' |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3703028 |
Assay Type: |
RNA in situ |
Annotation Date: |
2007-04-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3808024 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:3703046 |
Age: |
embryonic day 16.0-17.5 |
|
|
Specimen Label: |
3E |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Paina S |
Year: |
2011 |
Journal: |
J Neurosci |
Title: |
Wnt5a is a transcriptional target of Dlx homeogenes and promotes differentiation of interneuron progenitors in vitro and in vivo. |
Volume: |
31 |
Issue: |
7 |
Pages: |
2675-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ruest LB |
Year: |
2004 |
Journal: |
Development |
Title: |
Endothelin-A receptor-dependent and -independent signaling pathways in establishing mandibular identity. |
Volume: |
131 |
Issue: |
18 |
Pages: |
4413-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jeong J |
Year: |
2008 |
Journal: |
Development |
Title: |
Dlx genes pattern mammalian jaw primordium by regulating both lower jaw-specific and upper jaw-specific genetic programs. |
Volume: |
135 |
Issue: |
17 |
Pages: |
2905-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim KS |
Year: |
2013 |
Journal: |
Mech Dev |
Title: |
Endothelin regulates neural crest deployment and fate to form great vessels through Dlx5/Dlx6-independent mechanisms. |
Volume: |
130 |
Issue: |
11-12 |
Pages: |
553-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cajigas I |
Year: |
2018 |
Journal: |
Mol Cell |
Title: |
The Evf2 Ultraconserved Enhancer lncRNA Functionally and Spatially Organizes Megabase Distant Genes in the Developing Forebrain. |
Volume: |
71 |
Issue: |
6 |
Pages: |
956-972.e9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Poitras L |
Year: |
2010 |
Journal: |
Development |
Title: |
An SNP in an ultraconserved regulatory element affects Dlx5/Dlx6 regulation in the forebrain. |
Volume: |
137 |
Issue: |
18 |
Pages: |
3089-97 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
74
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Paciorkowski AR |
Year: |
2013 |
Journal: |
Neurogenetics |
Title: |
MEF2C Haploinsufficiency features consistent hyperkinesis, variable epilepsy, and has a role in dorsal and ventral neuronal developmental pathways. |
Volume: |
14 |
Issue: |
2 |
Pages: |
99-111 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen X |
Year: |
1996 |
Journal: |
Ann N Y Acad Sci |
Title: |
Dlx5 and Dlx6: an evolutionary conserved pair of murine homeobox genes expressed in the embryonic skeleton. |
Volume: |
785 |
|
Pages: |
38-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu JK |
Year: |
1997 |
Journal: |
Dev Dyn |
Title: |
Dlx genes encode DNA-binding proteins that are expressed in an overlapping and sequential pattern during basal ganglia differentiation. |
Volume: |
210 |
Issue: |
4 |
Pages: |
498-512 |
|
•
•
•
•
•
|
Publication |
First Author: |
Feng J |
Year: |
2006 |
Journal: |
Genes Dev |
Title: |
The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator. |
Volume: |
20 |
Issue: |
11 |
Pages: |
1470-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Birnbaum RY |
Year: |
2012 |
Journal: |
Hum Mol Genet |
Title: |
Functional characterization of tissue-specific enhancers in the DLX5/6 locus. |
Volume: |
21 |
Issue: |
22 |
Pages: |
4930-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stock DW |
Year: |
1996 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
The evolution of the vertebrate Dlx gene family. |
Volume: |
93 |
Issue: |
20 |
Pages: |
10858-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Myers AK |
Year: |
2020 |
Journal: |
Development |
Title: |
JNK signaling is required for proper tangential migration and laminar allocation of cortical interneurons. |
Volume: |
147 |
Issue: |
2 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Qiu M |
Year: |
1997 |
Journal: |
Dev Biol |
Title: |
Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches. |
Volume: |
185 |
Issue: |
2 |
Pages: |
165-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Faedo A |
Year: |
2004 |
Journal: |
Dev Dyn |
Title: |
Identification and characterization of a novel transcript down-regulated in Dlx1/Dlx2 and up-regulated in Pax6 mutant telencephalon. |
Volume: |
231 |
Issue: |
3 |
Pages: |
614-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ruest LB |
Year: |
2009 |
Journal: |
Dev Biol |
Title: |
Elucidating timing and function of endothelin-A receptor signaling during craniofacial development using neural crest cell-specific gene deletion and receptor antagonism. |
Volume: |
328 |
Issue: |
1 |
Pages: |
94-108 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yanagisawa H |
Year: |
2003 |
Journal: |
Development |
Title: |
Targeted deletion of a branchial arch-specific enhancer reveals a role of dHAND in craniofacial development. |
Volume: |
130 |
Issue: |
6 |
Pages: |
1069-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Radoja N |
Year: |
2007 |
Journal: |
Development |
Title: |
Homeobox gene Dlx3 is regulated by p63 during ectoderm development: relevance in the pathogenesis of ectodermal dysplasias. |
Volume: |
134 |
Issue: |
1 |
Pages: |
13-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Horike S |
Year: |
2005 |
Journal: |
Nat Genet |
Title: |
Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome. |
Volume: |
37 |
Issue: |
1 |
Pages: |
31-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Skogh C |
Year: |
2001 |
Journal: |
Mol Cell Neurosci |
Title: |
Generation of regionally specified neurons in expanded glial cultures derived from the mouse and human lateral ganglionic eminence. |
Volume: |
17 |
Issue: |
5 |
Pages: |
811-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhao Z |
Year: |
2000 |
Journal: |
Dev Genes Evol |
Title: |
Expression of Dlx genes during the development of the murine dentition. |
Volume: |
210 |
Issue: |
5 |
Pages: |
270-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stühmer T |
Year: |
2002 |
Journal: |
Development |
Title: |
Ectopic expression of the Dlx genes induces glutamic acid decarboxylase and Dlx expression. |
Volume: |
129 |
Issue: |
1 |
Pages: |
245-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Birnbaum RY |
Year: |
2012 |
Journal: |
Genome Res |
Title: |
Coding exons function as tissue-specific enhancers of nearby genes. |
Volume: |
22 |
Issue: |
6 |
Pages: |
1059-68 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kurihara Y |
Year: |
2023 |
Journal: |
J Clin Invest |
Title: |
Mandibulofacial dysostosis with alopecia results from ETAR gain-of-function mutations via allosteric effects on ligand binding. |
Volume: |
133 |
Issue: |
4 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kawata M |
Year: |
2017 |
Journal: |
PLoS One |
Title: |
Different regulation of limb development by p63 transcript variants. |
Volume: |
12 |
Issue: |
3 |
Pages: |
e0174122 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fazel Darbandi S |
Year: |
2021 |
Journal: |
Front Neurosci |
Title: |
Increased Sociability in Mice Lacking Intergenic Dlx Enhancers. |
Volume: |
15 |
|
Pages: |
718948 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ivey K |
Year: |
2003 |
Journal: |
Dev Biol |
Title: |
Galphaq and Galpha11 proteins mediate endothelin-1 signaling in neural crest-derived pharyngeal arch mesenchyme. |
Volume: |
255 |
Issue: |
2 |
Pages: |
230-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ozeki H |
Year: |
2004 |
Journal: |
Mech Dev |
Title: |
Endothelin-1 regulates the dorsoventral branchial arch patterning in mice. |
Volume: |
121 |
Issue: |
4 |
Pages: |
387-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bendall AJ |
Year: |
2000 |
Journal: |
Gene |
Title: |
Roles for Msx and Dlx homeoproteins in vertebrate development. |
Volume: |
247 |
Issue: |
1-2 |
Pages: |
17-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hevner RF |
Year: |
2003 |
Journal: |
Brain Res Dev Brain Res |
Title: |
Cajal-Retzius cells in the mouse: transcription factors, neurotransmitters, and birthdays suggest a pallial origin. |
Volume: |
141 |
Issue: |
1-2 |
Pages: |
39-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miller KA |
Year: |
2014 |
Journal: |
Mol Syndromol |
Title: |
A mouse splice-site mutant and individuals with atypical chromosome 22q11.2 deletions demonstrate the crucial role for crkl in craniofacial and pharyngeal development. |
Volume: |
5 |
Issue: |
6 |
Pages: |
276-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Anderson SA |
Year: |
1997 |
Journal: |
Neuron |
Title: |
Mutations of the homeobox genes Dlx-1 and Dlx-2 disrupt the striatal subventricular zone and differentiation of late born striatal neurons. |
Volume: |
19 |
Issue: |
1 |
Pages: |
27-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Toresson H |
Year: |
2000 |
Journal: |
Development |
Title: |
Genetic control of dorsal-ventral identity in the telencephalon: opposing roles for Pax6 and Gsh2. |
Volume: |
127 |
Issue: |
20 |
Pages: |
4361-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Woodside KJ |
Year: |
2004 |
Journal: |
Gene Expr Patterns |
Title: |
Expression of Dlx and Lhx family homeobox genes in fetal thymus and thymocytes. |
Volume: |
4 |
Issue: |
3 |
Pages: |
315-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Acampora D |
Year: |
1999 |
Journal: |
Development |
Title: |
Craniofacial, vestibular and bone defects in mice lacking the Distal-less-related gene Dlx5. |
Volume: |
126 |
Issue: |
17 |
Pages: |
3795-809 |
|
•
•
•
•
•
|
Publication |
First Author: |
Levi G |
Year: |
2003 |
Journal: |
Mol Cell Neurosci |
Title: |
The Dlx5 homeodomain gene is essential for olfactory development and connectivity in the mouse. |
Volume: |
22 |
Issue: |
4 |
Pages: |
530-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Toresson H |
Year: |
1999 |
Journal: |
Development |
Title: |
Retinoids are produced by glia in the lateral ganglionic eminence and regulate striatal neuron differentiation. |
Volume: |
126 |
Issue: |
6 |
Pages: |
1317-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Andrews GL |
Year: |
2003 |
Journal: |
Mol Cell Neurosci |
Title: |
Dlx transcription factors regulate differentiation of dopaminergic neurons of the ventral thalamus. |
Volume: |
23 |
Issue: |
1 |
Pages: |
107-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mastick GS |
Year: |
2001 |
Journal: |
Mol Cell Neurosci |
Title: |
Pax6 regulates the identity of embryonic diencephalic neurons. |
Volume: |
17 |
Issue: |
1 |
Pages: |
190-207 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ono R |
Year: |
2006 |
Journal: |
Nat Genet |
Title: |
Deletion of Peg10, an imprinted gene acquired from a retrotransposon, causes early embryonic lethality. |
Volume: |
38 |
Issue: |
1 |
Pages: |
101-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tiveron MC |
Year: |
2006 |
Journal: |
J Neurosci |
Title: |
Molecular interaction between projection neuron precursors and invading interneurons via stromal-derived factor 1 (CXCL12)/CXCR4 signaling in the cortical subventricular zone/intermediate zone. |
Volume: |
26 |
Issue: |
51 |
Pages: |
13273-8 |
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•
•
•
•
•
|
Publication |
First Author: |
Sun Y |
Year: |
2012 |
Journal: |
Dev Dyn |
Title: |
Asymmetric requirement of surface epithelial β-catenin during the upper and lower jaw development. |
Volume: |
241 |
Issue: |
4 |
Pages: |
663-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Riccomagno MM |
Year: |
2005 |
Journal: |
Genes Dev |
Title: |
Wnt-dependent regulation of inner ear morphogenesis is balanced by the opposing and supporting roles of Shh. |
Volume: |
19 |
Issue: |
13 |
Pages: |
1612-23 |
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•
•
•
•
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Publication |
First Author: |
Jia S |
Year: |
2013 |
Journal: |
Development |
Title: |
Roles of Bmp4 during tooth morphogenesis and sequential tooth formation. |
Volume: |
140 |
Issue: |
2 |
Pages: |
423-32 |
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•
•
•
•
|
Publication |
First Author: |
Long JE |
Year: |
2003 |
Journal: |
J Neurosci |
Title: |
DLX5 regulates development of peripheral and central components of the olfactory system. |
Volume: |
23 |
Issue: |
2 |
Pages: |
568-78 |
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•
•
•
•
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Publication |
First Author: |
Vanyai HK |
Year: |
2019 |
Journal: |
Development |
Title: |
MOZ directs the distal-less homeobox gene expression program during craniofacial development. |
Volume: |
146 |
Issue: |
14 |
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•
•
•
•
•
|
Publication |
First Author: |
He F |
Year: |
2014 |
Journal: |
Dev Biol |
Title: |
Directed Bmp4 expression in neural crest cells generates a genetic model for the rare human bony syngnathia birth defect. |
Volume: |
391 |
Issue: |
2 |
Pages: |
170-81 |
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•
•
•
•
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Publication |
First Author: |
Yamagishi C |
Year: |
2006 |
Journal: |
Pediatr Res |
Title: |
Sonic hedgehog is essential for first pharyngeal arch development. |
Volume: |
59 |
Issue: |
3 |
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•
•
•
•
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Publication |
First Author: |
Garel S |
Year: |
1999 |
Journal: |
Development |
Title: |
Ebf1 controls early cell differentiation in the embryonic striatum. |
Volume: |
126 |
Issue: |
23 |
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5285-94 |
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•
•
•
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Publication |
First Author: |
Liu C |
Year: |
2003 |
Journal: |
Development |
Title: |
A role for the mesenchymal T-box gene Brachyury in AER formation during limb development. |
Volume: |
130 |
Issue: |
7 |
Pages: |
1327-37 |
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•
•
•
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Publication |
First Author: |
Van Otterloo E |
Year: |
2018 |
Journal: |
Development |
Title: |
AP-2α and AP-2β cooperatively orchestrate homeobox gene expression during branchial arch patterning. |
Volume: |
145 |
Issue: |
2 |
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•
•
•
•
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Publication |
First Author: |
Yun K |
Year: |
2002 |
Journal: |
Development |
Title: |
Modulation of the notch signaling by Mash1 and Dlx1/2 regulates sequential specification and differentiation of progenitor cell types in the subcortical telencephalon. |
Volume: |
129 |
Issue: |
21 |
Pages: |
5029-40 |
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•
•
•
•
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Publication |
First Author: |
Jin YR |
Year: |
2011 |
Journal: |
Dev Biol |
Title: |
The canonical Wnt signaling activator, R-spondin2, regulates craniofacial patterning and morphogenesis within the branchial arch through ectodermal-mesenchymal interaction. |
Volume: |
352 |
Issue: |
1 |
Pages: |
1-13 |
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•
•
•
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Publication |
First Author: |
Song H |
Year: |
2015 |
Journal: |
Dev Biol |
Title: |
Ascl1 and Helt act combinatorially to specify thalamic neuronal identity by repressing Dlxs activation. |
Volume: |
398 |
Issue: |
2 |
Pages: |
280-91 |
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•
•
•
•
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Publication |
First Author: |
Inman KE |
Year: |
2013 |
Journal: |
PLoS Genet |
Title: |
Interaction between Foxc1 and Fgf8 during mammalian jaw patterning and in the pathogenesis of syngnathia. |
Volume: |
9 |
Issue: |
12 |
Pages: |
e1003949 |
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•
•
•
•
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Publication |
First Author: |
Gu R |
Year: |
2022 |
Journal: |
Development |
Title: |
Single-cell transcriptomic signatures and gene regulatory networks modulated by Wls in mammalian midline facial formation and clefts. |
Volume: |
149 |
Issue: |
14 |
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•
•
•
•
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Publication |
First Author: |
MartÃn-Ibáñez R |
Year: |
2017 |
Journal: |
Development |
Title: |
Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons. |
Volume: |
144 |
Issue: |
8 |
Pages: |
1566-1577 |
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•
•
•
•
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Publication |
First Author: |
Capellini TD |
Year: |
2006 |
Journal: |
Development |
Title: |
Pbx1/Pbx2 requirement for distal limb patterning is mediated by the hierarchical control of Hox gene spatial distribution and Shh expression. |
Volume: |
133 |
Issue: |
11 |
Pages: |
2263-73 |
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•
•
•
•
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Publication |
First Author: |
Hill CR |
Year: |
2014 |
Journal: |
Bone |
Title: |
Jagged1 is essential for osteoblast development during maxillary ossification. |
Volume: |
62 |
|
Pages: |
10-21 |
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•
•
•
•
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Publication |
First Author: |
Maclean G |
Year: |
2009 |
Journal: |
Dev Dyn |
Title: |
Genetic disruption of CYP26B1 severely affects development of neural crest derived head structures, but does not compromise hindbrain patterning. |
Volume: |
238 |
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