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Search results 101 to 200 out of 5576 for Kl

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Type Details Score
Publication
First Author: Suga T
Year: 2000
Journal: Am J Respir Cell Mol Biol
Title: Disruption of the klotho gene causes pulmonary emphysema in mice. Defect in maintenance of pulmonary integrity during postnatal life.
Volume: 22
Issue: 1
Pages: 26-33
Publication
First Author: Nakano-Kurimoto R
Year: 2009
Journal: Am J Physiol Heart Circ Physiol
Title: Replicative senescence of vascular smooth muscle cells enhances the calcification through initiating the osteoblastic transition.
Volume: 297
Issue: 5
Pages: H1673-84
Publication
First Author: Kashimada K
Year: 2002
Journal: J Endocrinol
Title: Defects in growth and bone metabolism in klotho mutant mice are resistant to GH treatment.
Volume: 174
Issue: 3
Pages: 403-10
Publication
First Author: Manabe N
Year: 2001
Journal: J Immunol
Title: Connection between B lymphocyte and osteoclast differentiation pathways.
Volume: 167
Issue: 5
Pages: 2625-31
Publication
First Author: Yamashita T
Year: 2001
Journal: J Endocrinol
Title: Klotho-deficient mice are resistant to bone loss induced by unloading due to sciatic neurectomy.
Volume: 168
Issue: 2
Pages: 347-51
Publication
First Author: Voelkl J
Year: 2018
Journal: J Am Soc Nephrol
Title: Zinc Inhibits Phosphate-Induced Vascular Calcification through TNFAIP3-Mediated Suppression of NF-κB.
Volume: 29
Issue: 6
Pages: 1636-1648
Publication
First Author: Nakamura T
Year: 2002
Journal: Jpn J Pharmacol
Title: Production of nitric oxide, but not prostacyclin, is reduced in klotho mice.
Volume: 89
Issue: 2
Pages: 149-56
Publication
First Author: Sahu A
Year: 2018
Journal: Nat Commun
Title: Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration.
Volume: 9
Issue: 1
Pages: 4859
Publication  
First Author: Jin Z
Year: 2021
Journal: Oxid Med Cell Longev
Title: Exercise-Linked Irisin Prevents Mortality and Enhances Cognition in a Mice Model of Cerebral Ischemia by Regulating Klotho Expression.
Volume: 2021
Pages: 1697070
Publication
First Author: Brownstein CA
Year: 2010
Journal: Endocrinology
Title: Increased bone volume and correction of HYP mouse hypophosphatemia in the Klotho/HYP mouse.
Volume: 151
Issue: 2
Pages: 492-501
Publication  
First Author: Leifheit-Nestler M
Year: 2018
Journal: Front Endocrinol (Lausanne)
Title: Impact of Altered Mineral Metabolism on Pathological Cardiac Remodeling in Elevated Fibroblast Growth Factor 23.
Volume: 9
Pages: 333
Publication
First Author: Singh A
Year: 2019
Journal: Aging Cell
Title: Noncoding variations in Cyp24a1 gene are associated with Klotho-mediated aging phenotypes in different strains of mice.
Volume: 18
Issue: 3
Pages: e12949
Publication
First Author: Kuro-o M
Year: 1997
Journal: Nature
Title: Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
Volume: 390
Issue: 6655
Pages: 45-51
Publication
First Author: Zeldich E
Year: 2014
Journal: J Biol Chem
Title: The neuroprotective effect of Klotho is mediated via regulation of members of the redox system.
Volume: 289
Issue: 35
Pages: 24700-15
Publication
First Author: Hikone K
Year: 2017
Journal: J Histochem Cytochem
Title: Histochemical Examination on Periodontal Tissues of Klotho-Deficient Mice Fed With Phosphate-Insufficient Diet.
Volume: 65
Issue: 4
Pages: 207-221
Publication  
First Author: Li Q
Year: 2017
Journal: Neuroscience
Title: Klotho regulates CA1 hippocampal synaptic plasticity.
Volume: 347
Pages: 123-133
Publication
First Author: Sato A
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Morphological mechanism of the development of pulmonary emphysema in klotho mice.
Volume: 104
Issue: 7
Pages: 2361-5
Publication
First Author: Faul C
Year: 2011
Journal: J Clin Invest
Title: FGF23 induces left ventricular hypertrophy.
Volume: 121
Issue: 11
Pages: 4393-408
Publication
First Author: Kawarazaki W
Year: 2020
Journal: J Clin Invest
Title: Salt causes aging-associated hypertension via vascular Wnt5a under Klotho deficiency.
Volume: 130
Issue: 8
Pages: 4152-4166
Publication
First Author: Gao D
Year: 2016
Journal: Hypertension
Title: Activation of SIRT1 Attenuates Klotho Deficiency-Induced Arterial Stiffness and Hypertension by Enhancing AMP-Activated Protein Kinase Activity.
Volume: 68
Issue: 5
Pages: 1191-1199
Publication  
First Author: Toan NK
Year: 2021
Journal: Int J Mol Sci
Title: Choline Acetyltransferase Induces the Functional Regeneration of the Salivary Gland in Aging SAMP1/Kl -/- Mice.
Volume: 22
Issue: 1
Publication
First Author: Xie J
Year: 2015
Journal: J Am Soc Nephrol
Title: Soluble Klotho Protects against Uremic Cardiomyopathy Independently of Fibroblast Growth Factor 23 and Phosphate.
Volume: 26
Issue: 5
Pages: 1150-60
Publication
First Author: Hu MC
Year: 2013
Journal: Kidney Int
Title: The erythropoietin receptor is a downstream effector of Klotho-induced cytoprotection.
Volume: 84
Issue: 3
Pages: 468-81
Publication
First Author: Urakawa I
Year: 2006
Journal: Nature
Title: Klotho converts canonical FGF receptor into a specific receptor for FGF23.
Volume: 444
Issue: 7120
Pages: 770-4
Publication  
First Author: Shin EJ
Year: 2014
Journal: Int J Neuropsychopharmacol
Title: Melatonin attenuates memory impairment induced by Klotho gene deficiency via interactive signaling between MT2 receptor, ERK, and Nrf2-related antioxidant potential.
Volume: 18
Issue: 6
Publication
First Author: Kusaba T
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Klotho is associated with VEGF receptor-2 and the transient receptor potential canonical-1 Ca2+ channel to maintain endothelial integrity.
Volume: 107
Issue: 45
Pages: 19308-13
Publication  
First Author: Liu L
Year: 2018
Journal: J Mol Cell Cardiol
Title: High phosphate-induced downregulation of PPARγ contributes to CKD-associated vascular calcification.
Volume: 114
Pages: 264-275
Publication
First Author: Izbeki F
Year: 2010
Journal: J Physiol
Title: Loss of Kitlow progenitors, reduced stem cell factor and high oxidative stress underlie gastric dysfunction in progeric mice.
Volume: 588
Issue: Pt 16
Pages: 3101-17
Publication
First Author: Wang X
Year: 2020
Journal: Biochem Biophys Res Commun
Title: ROS/p38MAPK-induced lamin B1 accumulation promotes chronic kidney disease-associated vascular smooth muscle cells senescence.
Volume: 531
Issue: 2
Pages: 187-194
Publication
First Author: Asai O
Year: 2012
Journal: Kidney Int
Title: Decreased renal α-Klotho expression in early diabetic nephropathy in humans and mice and its possible role in urinary calcium excretion.
Volume: 81
Issue: 6
Pages: 539-47
Publication
First Author: Shiraki-Iida T
Year: 1998
Journal: FEBS Lett
Title: Structure of the mouse klotho gene and its two transcripts encoding membrane and secreted protein.
Volume: 424
Issue: 1-2
Pages: 6-10
Publication
First Author: Kim SJ
Year: 2017
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Klotho, an antiaging molecule, attenuates oxidant-induced alveolar epithelial cell mtDNA damage and apoptosis.
Volume: 313
Issue: 1
Pages: L16-L26
Publication
First Author: Asada N
Year: 2013
Journal: Cell Stem Cell
Title: Matrix-embedded osteocytes regulate mobilization of hematopoietic stem/progenitor cells.
Volume: 12
Issue: 6
Pages: 737-47
Publication  
First Author: Ain Q
Year: 2022
Journal: Int J Mol Sci
Title: Optimized Protocol for Proportionate CNS Cell Retrieval as a Versatile Platform for Cellular and Molecular Phenomapping in Aging and Neurodegeneration.
Volume: 23
Issue: 6
Publication
First Author: Chen J
Year: 2016
Journal: Aging Cell
Title: Deficiency in the anti-aging gene Klotho promotes aortic valve fibrosis through AMPKα-mediated activation of RUNX2.
Volume: 15
Issue: 5
Pages: 853-60
Publication
First Author: Truong Thuy Nguyen V
Year: 2023
Journal: Cell Mol Gastroenterol Hepatol
Title: Insulin-Like Growth Factor1 Preserves Gastric Pacemaker Cells and Motor Function in Aging via ERK1/2 Activation.
Volume: 16
Issue: 3
Pages: 369-383
Publication
First Author: Park SJ
Year: 2013
Journal: Neuropsychopharmacology
Title: Inactivation of JAK2/STAT3 signaling axis and downregulation of M1 mAChR cause cognitive impairment in klotho mutant mice, a genetic model of aging.
Volume: 38
Issue: 8
Pages: 1426-37
Publication
First Author: Carraway KL 3rd
Year: 1996
Journal: Bioessays
Title: Involvement of the neuregulins and their receptors in cardiac and neural development.
Volume: 18
Issue: 4
Pages: 263-6
Publication
First Author: Xing Y
Year: 2018
Journal: J Immunol
Title: Thymic Epithelial Cell Support of Thymopoiesis Does Not Require Klotho.
Volume: 201
Issue: 11
Pages: 3320-3328
Publication
First Author: Ohnishi M
Year: 2011
Journal: FASEB J
Title: Dietary and genetic evidence for enhancing glucose metabolism and reducing obesity by inhibiting klotho functions.
Volume: 25
Issue: 6
Pages: 2031-9
Publication
First Author: Tucker Zhou TB
Year: 2013
Journal: J Biol Chem
Title: Biochemical and functional characterization of the klotho-VS polymorphism implicated in aging and disease risk.
Volume: 288
Issue: 51
Pages: 36302-11
Publication
First Author: Tsujikawa H
Year: 2003
Journal: Mol Endocrinol
Title: Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system.
Volume: 17
Issue: 12
Pages: 2393-403
Publication
First Author: Vanhooren V
Year: 2011
Journal: Aging Cell
Title: Alteration in N-glycomics during mouse aging: a role for FUT8.
Volume: 10
Issue: 6
Pages: 1056-66
Publication
First Author: Brobey RK
Year: 2015
Journal: PLoS One
Title: Klotho Protects Dopaminergic Neuron Oxidant-Induced Degeneration by Modulating ASK1 and p38 MAPK Signaling Pathways.
Volume: 10
Issue: 10
Pages: e0139914
Publication
First Author: Takei Y
Year: 2012
Journal: Bone
Title: Stanniocalcin 2 is associated with ectopic calcification in α-klotho mutant mice and inhibits hyperphosphatemia-induced calcification in aortic vascular smooth muscle cells.
Volume: 50
Issue: 4
Pages: 998-1005
Publication
First Author: Rangiani A
Year: 2012
Journal: Int J Oral Sci
Title: Dentin matrix protein 1 and phosphate homeostasis are critical for postnatal pulp, dentin and enamel formation.
Volume: 4
Issue: 4
Pages: 189-95
Publication
First Author: Rangiani A
Year: 2012
Journal: PLoS One
Title: Protective roles of DMP1 in high phosphate homeostasis.
Volume: 7
Issue: 8
Pages: e42329
Publication
First Author: Esapa CT
Year: 2015
Journal: PLoS One
Title: N-ethyl-N-Nitrosourea (ENU) induced mutations within the klotho gene lead to ectopic calcification and reduced lifespan in mouse models.
Volume: 10
Issue: 4
Pages: e0122650
Publication  
First Author: Vo HT
Year: 2019
Journal: Mol Cell Neurosci
Title: Klotho deficiency affects the spine morphology and network synchronization of neurons.
Volume: 98
Pages: 1-11
Publication
First Author: Huang Y
Year: 2020
Journal: Nat Commun
Title: IRF1-mediated downregulation of PGC1α contributes to cardiorenal syndrome type 4.
Volume: 11
Issue: 1
Pages: 4664
Publication
First Author: Singh S
Year: 2016
Journal: Kidney Int
Title: Fibroblast growth factor 23 directly targets hepatocytes to promote inflammation in chronic kidney disease.
Volume: 90
Issue: 5
Pages: 985-996
Publication
First Author: Kurosu H
Year: 2005
Journal: Science
Title: Suppression of aging in mice by the hormone Klotho.
Volume: 309
Issue: 5742
Pages: 1829-33
Publication
First Author: Voelkl J
Year: 2018
Journal: J Clin Invest
Title: SGK1 induces vascular smooth muscle cell calcification through NF-κB signaling.
Volume: 128
Issue: 7
Pages: 3024-3040
Publication
First Author: Taylor A
Year: 2019
Journal: Sci Rep
Title: FGFR4 does not contribute to progression of chronic kidney disease.
Volume: 9
Issue: 1
Pages: 14023
Publication
First Author: Hayashi Y
Year: 2021
Journal: Cell Mol Gastroenterol Hepatol
Title: Wnt-induced, TRP53-mediated Cell Cycle Arrest of Precursors Underlies Interstitial Cell of Cajal Depletion During Aging.
Volume: 11
Issue: 1
Pages: 117-145
Publication
First Author: Eren M
Year: 2017
Journal: Sci Adv
Title: PAI-1 is a critical regulator of FGF23 homeostasis.
Volume: 3
Issue: 9
Pages: e1603259
Publication
First Author: Wehling-Henricks M
Year: 2016
Journal: Hum Mol Genet
Title: Klotho gene silencing promotes pathology in the mdx mouse model of Duchenne muscular dystrophy.
Volume: 25
Issue: 12
Pages: 2465-2482
Publication  
First Author: Nguyen BT
Year: 2022
Journal: Free Radic Biol Med
Title: Ginsenoside Re attenuates memory impairments in aged Klotho deficient mice via interactive modulations of angiotensin II AT1 receptor, Nrf2 and GPx-1 gene.
Volume: 189
Pages: 2-19
Publication  
First Author: Xie J
Year: 2012
Journal: Nat Commun
Title: Cardioprotection by Klotho through downregulation of TRPC6 channels in the mouse heart.
Volume: 3
Pages: 1238
Publication
First Author: Eren M
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice.
Volume: 111
Issue: 19
Pages: 7090-5
Publication
First Author: Haruna Y
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Amelioration of progressive renal injury by genetic manipulation of Klotho gene.
Volume: 104
Issue: 7
Pages: 2331-6
Publication
First Author: Yamashita T
Year: 2002
Journal: Endocrinology
Title: Double mutations in klotho and osteoprotegerin gene loci rescued osteopetrotic phenotype.
Volume: 143
Issue: 12
Pages: 4711-7
Publication
First Author: Shi M
Year: 2016
Journal: J Am Soc Nephrol
Title: αKlotho Mitigates Progression of AKI to CKD through Activation of Autophagy.
Volume: 27
Issue: 8
Pages: 2331-45
Publication
First Author: Liu H
Year: 2007
Journal: Science
Title: Augmented Wnt signaling in a mammalian model of accelerated aging.
Volume: 317
Issue: 5839
Pages: 803-6
Publication  
First Author: Chen WY
Year: 2020
Journal: Int J Mol Sci
Title: Soluble Alpha-Klotho Alleviates Cardiac Fibrosis without Altering Cardiomyocytes Renewal.
Volume: 21
Issue: 6
Publication  
First Author: Xiao Z
Year: 2019
Journal: JCI Insight
Title: FGF23 expression is stimulated in transgenic α-Klotho longevity mouse model.
Volume: 4
Issue: 23
Publication
First Author: Smith RC
Year: 2012
Journal: J Clin Invest
Title: Circulating αKlotho influences phosphate handling by controlling FGF23 production.
Volume: 122
Issue: 12
Pages: 4710-5
Publication
First Author: Takeshita K
Year: 2004
Journal: Circulation
Title: Sinoatrial node dysfunction and early unexpected death of mice with a defect of klotho gene expression.
Volume: 109
Issue: 14
Pages: 1776-82
Publication
First Author: Mencke R
Year: 2019
Journal: Am J Pathol
Title: Klotho Deficiency Induces Arteriolar Hyalinosis in a Trade-Off with Vascular Calcification.
Volume: 189
Issue: 12
Pages: 2503-2515
Publication
First Author: Ma Y
Year: 2017
Journal: Endocrinology
Title: FGF23 Is Not Required to Regulate Fetal Phosphorus Metabolism but Exerts Effects Within 12 Hours After Birth.
Volume: 158
Issue: 2
Pages: 252-263
Publication
First Author: Hum JM
Year: 2017
Journal: J Am Soc Nephrol
Title: Chronic Hyperphosphatemia and Vascular Calcification Are Reduced by Stable Delivery of Soluble Klotho.
Volume: 28
Issue: 4
Pages: 1162-1174
Publication
First Author: Cheek JD
Year: 2012
Journal: J Mol Cell Cardiol
Title: Differential activation of valvulogenic, chondrogenic, and osteogenic pathways in mouse models of myxomatous and calcific aortic valve disease.
Volume: 52
Issue: 3
Pages: 689-700
Publication
First Author: Carraway KL 3rd
Year: 2006
Journal: Cancer Cell
Title: Co-opted integrin signaling in ErbB2-induced mammary tumor progression.
Volume: 10
Issue: 2
Pages: 93-5
Publication
First Author: Andrukhova O
Year: 2012
Journal: Bone
Title: FGF23 acts directly on renal proximal tubules to induce phosphaturia through activation of the ERK1/2-SGK1 signaling pathway.
Volume: 51
Issue: 3
Pages: 621-8
Publication
First Author: Ohnishi M
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Genetic induction of phosphate toxicity significantly reduces the survival of hypercholesterolemic obese mice.
Volume: 415
Issue: 3
Pages: 434-8
Publication
First Author: Webster R
Year: 2016
Journal: Am J Physiol Renal Physiol
Title: Klotho/fibroblast growth factor 23- and PTH-independent estrogen receptor-α-mediated direct downregulation of NaPi-IIa by estrogen in the mouse kidney.
Volume: 311
Issue: 2
Pages: F249-59
Publication
First Author: Zhu L
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Klotho controls the brain-immune system interface in the choroid plexus.
Volume: 115
Issue: 48
Pages: E11388-E11396
Publication  
First Author: Laszczyk AM
Year: 2017
Journal: Neurobiol Aging
Title: Klotho regulates postnatal neurogenesis and protects against age-related spatial memory loss.
Volume: 59
Pages: 41-54
Publication  
First Author: Chakrabarti M
Year: 2022
Journal: Front Cardiovasc Med
Title: Increased TGFβ1 and SMAD3 Contribute to Age-Related Aortic Valve Calcification.
Volume: 9
Pages: 770065
Publication
First Author: Collin-Osdoby P
Year: 2004
Journal: Circ Res
Title: Regulation of vascular calcification by osteoclast regulatory factors RANKL and osteoprotegerin.
Volume: 95
Issue: 11
Pages: 1046-57
Publication  
First Author: Sato S
Year: 2015
Journal: Nat Commun
Title: Ablation of the p16(INK4a) tumour suppressor reverses ageing phenotypes of klotho mice.
Volume: 6
Pages: 7035
Publication
First Author: Watanabe R
Year: 2017
Journal: Sci Rep
Title: Enpp1 is an anti-aging factor that regulates Klotho under phosphate overload conditions.
Volume: 7
Issue: 1
Pages: 7786
Publication    
First Author: Watanabe M
Year: 2017
Journal: Elife
Title: Type XVII collagen coordinates proliferation in the interfollicular epidermis.
Volume: 6
Publication
First Author: Shi M
Year: 2020
Journal: FASEB J
Title: The tripartite interaction of phosphate, autophagy, and αKlotho in health maintenance.
Volume: 34
Issue: 2
Pages: 3129-3150
Publication  
First Author: Brommage R
Year: 2014
Journal: Bone Res
Title: High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes.
Volume: 2
Pages: 14034
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory