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Search results 1401 to 1500 out of 1660 for Arpp21

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Type Details Score
Publication
17913918 | J:125592
First Author: Li T
Year: 2007
Journal: J Neurosci
Title: Moderate reduction of gamma-secretase attenuates amyloid burden and limits mechanism-based liabilities.
Volume: 27
Issue: 40
Pages: 10849-59
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Publication
31794021 | J:284850
First Author: Koronyo-Hamaoui M
Year: 2020
Journal: Brain
Title: Peripherally derived angiotensin converting enzyme-enhanced macrophages alleviate Alzheimer-related disease.
Volume: 143
Issue: 1
Pages: 336-358
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Publication
22820466 | J:190064
First Author: Um JW
Year: 2012
Journal: Nat Neurosci
Title: Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons.
Volume: 15
Issue: 9
Pages: 1227-35
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Publication
29520217 | J:289791
 
First Author: Turnbull MT
Year: 2018
Journal: Front Mol Neurosci
Title: Acute Down-regulation of BDNF Signaling Does Not Replicate Exacerbated Amyloid-β Levels and Cognitive Impairment Induced by Cholinergic Basal Forebrain Lesion.
Volume: 11
Pages: 51
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Publication
27552836 | J:264266
First Author: Huo Q
Year: 2017
Journal: Cereb Cortex
Title: Prefrontal Cortical GABAergic Dysfunction Contributes to Aberrant UP-State Duration in APP Knockout Mice.
Volume: 27
Issue: 8
Pages: 4060-4072
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Publication
34107254 | J:311267
First Author: Hu Y
Year: 2021
Journal: Cell Rep
Title: Replicative senescence dictates the emergence of disease-associated microglia and contributes to Aβ pathology.
Volume: 35
Issue: 10
Pages: 109228
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Publication
23038755 | J:341942
First Author: Kraft AW
Year: 2013
Journal: FASEB J
Title: Attenuating astrocyte activation accelerates plaque pathogenesis in APP/PS1 mice.
Volume: 27
Issue: 1
Pages: 187-98
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Publication
34315531 | J:310841
First Author: Jeong A
Year: 2021
Journal: Acta Neuropathol Commun
Title: Protein farnesylation is upregulated in Alzheimer's human brains and neuron-specific suppression of farnesyltransferase mitigates pathogenic processes in Alzheimer's model mice.
Volume: 9
Issue: 1
Pages: 129
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Publication
25485684 | J:219607
First Author: Johansson JU
Year: 2015
Journal: J Clin Invest
Title: Prostaglandin signaling suppresses beneficial microglial function in Alzheimer's disease models.
Volume: 125
Issue: 1
Pages: 350-64
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Publication
24760848 | J:210613
First Author: Woodling NS
Year: 2014
Journal: J Neurosci
Title: Suppression of Alzheimer-associated inflammation by microglial prostaglandin-E2 EP4 receptor signaling.
Volume: 34
Issue: 17
Pages: 5882-94
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Publication
23799536 | J:221229
 
First Author: Frenkel D
Year: 2013
Journal: Nat Commun
Title: Scara1 deficiency impairs clearance of soluble amyloid-β by mononuclear phagocytes and accelerates Alzheimer's-like disease progression.
Volume: 4
Pages: 2030
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Publication
27748574 | J:252038
First Author: Jackson RJ
Year: 2016
Journal: Eur J Neurosci
Title: Human tau increases amyloid β plaque size but not amyloid β-mediated synapse loss in a novel mouse model of Alzheimer's disease.
Volume: 44
Issue: 12
Pages: 3056-3066
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Publication
28416393 | J:259472
 
First Author: Davis SA
Year: 2017
Journal: Neurobiol Dis
Title: TDP-43 expression influences amyloidβ plaque deposition and tau aggregation.
Volume: 103
Pages: 154-162
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Publication
26290229 | J:226016
First Author: Gontier G
Year: 2015
Journal: J Neurosci
Title: Blocking IGF Signaling in Adult Neurons Alleviates Alzheimer's Disease Pathology through Amyloid-β Clearance.
Volume: 35
Issue: 33
Pages: 11500-13
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Publication
21573167 | J:172426
First Author: Phillips M
Year: 2011
Journal: PLoS One
Title: Olfactory and visuospatial learning and memory performance in two strains of Alzheimer's disease model mice--a longitudinal study.
Volume: 6
Issue: 5
Pages: e19567
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Publication
18566467 | J:141764
First Author: Ning A
Year: 2008
Journal: Invest Ophthalmol Vis Sci
Title: Amyloid-beta deposits lead to retinal degeneration in a mouse model of Alzheimer disease.
Volume: 49
Issue: 11
Pages: 5136-43
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Publication
24136196 | J:207213
First Author: Cheng S
Year: 2013
Journal: J Biol Chem
Title: Farnesyltransferase haplodeficiency reduces neuropathology and rescues cognitive function in a mouse model of Alzheimer disease.
Volume: 288
Issue: 50
Pages: 35952-60
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Publication
21307265 | J:169451
First Author: Wang YJ
Year: 2011
Journal: J Neurosci
Title: p75NTR regulates Abeta deposition by increasing Abeta production but inhibiting Abeta aggregation with its extracellular domain.
Volume: 31
Issue: 6
Pages: 2292-304
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Publication
18374455 | J:155160
First Author: Sotthibundhu A
Year: 2009
Journal: Neurobiol Aging
Title: Abeta(1-42) stimulates adult SVZ neurogenesis through the p75 neurotrophin receptor.
Volume: 30
Issue: 12
Pages: 1975-85
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Publication
21611169 | J:172735
First Author: Israeli E
Year: 2011
Journal: PLoS One
Title: α-Synuclein expression selectively affects tumorigenesis in mice modeling Parkinson's disease.
Volume: 6
Issue: 5
Pages: e19622
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Publication
34209113 | J:322203
 
First Author: Camargo LC
Year: 2021
Journal: Int J Mol Sci
Title: PEAβ Triggers Cognitive Decline and Amyloid Burden in a Novel Mouse Model of Alzheimer's Disease.
Volume: 22
Issue: 13
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Publication
31018141 | J:284370
First Author: Sala Frigerio C
Year: 2019
Journal: Cell Rep
Title: The Major Risk Factors for Alzheimer's Disease: Age, Sex, and Genes Modulate the Microglia Response to Aβ Plaques.
Volume: 27
Issue: 4
Pages: 1293-1306.e6
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Publication
22323736 | J:181688
First Author: Cramer PE
Year: 2012
Journal: Science
Title: ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models.
Volume: 335
Issue: 6075
Pages: 1503-6
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Publication
27723233 | J:238754
First Author: Martin E
Year: 2017
Journal: Aging Cell
Title: Distinct inflammatory phenotypes of microglia and monocyte-derived macrophages in Alzheimer's disease models: effects of aging and amyloid pathology.
Volume: 16
Issue: 1
Pages: 27-38
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Publication
29483128 | J:261602
First Author: Ulrich JD
Year: 2018
Journal: J Exp Med
Title: ApoE facilitates the microglial response to amyloid plaque pathology.
Volume: 215
Issue: 4
Pages: 1047-1058
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Publication
17563384 | J:122372
First Author: Zelcer N
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Attenuation of neuroinflammation and Alzheimer's disease pathology by liver x receptors.
Volume: 104
Issue: 25
Pages: 10601-6
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Publication
32582162 | J:311289
 
First Author: Gericke C
Year: 2020
Journal: Front Immunol
Title: Oligomeric Forms of Human Amyloid-Beta(1-42) Inhibit Antigen Presentation.
Volume: 11
Pages: 1029
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Publication
24133259 | J:202745
First Author: Ostapchenko VG
Year: 2013
Journal: J Neurosci
Title: The prion protein ligand, stress-inducible phosphoprotein 1, regulates amyloid-β oligomer toxicity.
Volume: 33
Issue: 42
Pages: 16552-64
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Strain
MGI:6148787 | B6.Cg-Nfatc2<tm1Rao> Tg(APPswe,PSEN1dE9)85Dbo/Mmmh
Attribute String: mutant strain, congenic, transgenic, targeted mutation
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Publication
28505967 | J:272736
First Author: Manocha GD
Year: 2017
Journal: J Alzheimers Dis
Title: NFATc2 Modulates Microglial Activation in the AβPP/PS1 Mouse Model of Alzheimer's Disease.
Volume: 58
Issue: 3
Pages: 775-787
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Publication
26619807 | J:240007
First Author: Sharoar MG
Year: 2016
Journal: Mol Psychiatry
Title: Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease.
Volume: 21
Issue: 9
Pages: 1263-71
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Publication
20739292 | J:166877
First Author: Lefterov I
Year: 2010
Journal: J Biol Chem
Title: Apolipoprotein A-I deficiency increases cerebral amyloid angiopathy and cognitive deficits in APP/PS1DeltaE9 mice.
Volume: 285
Issue: 47
Pages: 36945-57
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Publication
28612290 | J:311298
First Author: Haure-Mirande JV
Year: 2017
Journal: Acta Neuropathol
Title: Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer's pathology.
Volume: 134
Issue: 5
Pages: 769-788
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Publication
23933749 | J:203865
First Author: Ma T
Year: 2013
Journal: Nat Neurosci
Title: Suppression of eIF2α kinases alleviates Alzheimer's disease-related plasticity and memory deficits.
Volume: 16
Issue: 9
Pages: 1299-305
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Publication
31363064 | J:287771
First Author: Martínez-Mármol R
Year: 2019
Journal: J Neurosci
Title: p110δ PI3-Kinase Inhibition Perturbs APP and TNFα Trafficking, Reduces Plaque Burden, Dampens Neuroinflammation, and Prevents Cognitive Decline in an Alzheimer's Disease Mouse Model.
Volume: 39
Issue: 40
Pages: 7976-7991
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Publication
36229920 | J:339345
First Author: Yang Y
Year: 2023
Journal: Hum Mol Genet
Title: NRSF regulates age-dependently cognitive ability and its conditional knockout in APP/PS1 mice moderately alters AD-like pathology.
Volume: 32
Issue: 16
Pages: 2558-2575
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Publication
19204288 | J:146447
First Author: Halford RW
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Reduction of cholesterol synthesis in the mouse brain does not affect amyloid formation in Alzheimer's disease, but does extend lifespan.
Volume: 106
Issue: 9
Pages: 3502-6
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Publication
26780512 | J:234430
First Author: Knafo S
Year: 2016
Journal: Nat Neurosci
Title: PTEN recruitment controls synaptic and cognitive function in Alzheimer's models.
Volume: 19
Issue: 3
Pages: 443-53
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Publication
23831375 | J:211720
First Author: Ordóñez-Gutiérrez L
Year: 2013
Journal: Neurobiol Aging
Title: Cellular prion protein modulates β-amyloid deposition in aged APP/PS1 transgenic mice.
Volume: 34
Issue: 12
Pages: 2793-804
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Publication
33398092 | J:311559
First Author: Bao WD
Year: 2021
Journal: Cell Death Differ
Title: Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer's disease.
Volume: 28
Issue: 5
Pages: 1548-1562
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Publication
25619654 | J:219701
First Author: Guillot-Sestier MV
Year: 2015
Journal: Neuron
Title: Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology.
Volume: 85
Issue: 3
Pages: 534-48
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Publication
33685483 | J:320471
First Author: Roca-Agujetas V
Year: 2021
Journal: Mol Neurodegener
Title: Cholesterol alters mitophagy by impairing optineurin recruitment and lysosomal clearance in Alzheimer's disease.
Volume: 16
Issue: 1
Pages: 15
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Publication
24815354 | J:211660
First Author: Barbero-Camps E
Year: 2014
Journal: Am J Pathol
Title: Endoplasmic reticulum stress mediates amyloid β neurotoxicity via mitochondrial cholesterol trafficking.
Volume: 184
Issue: 7
Pages: 2066-81
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Publication
23648430 | J:199130
First Author: Barbero-Camps E
Year: 2013
Journal: Hum Mol Genet
Title: APP/PS1 mice overexpressing SREBP-2 exhibit combined Aβ accumulation and tau pathology underlying Alzheimer's disease.
Volume: 22
Issue: 17
Pages: 3460-76
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Publication
29862881 | J:264849
First Author: Barbero-Camps E
Year: 2018
Journal: Autophagy
Title: Cholesterol impairs autophagy-mediated clearance of amyloid beta while promoting its secretion.
Volume: 14
Issue: 7
Pages: 1129-1154
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Publication
21587206 | J:173362
First Author: Tamayev R
Year: 2011
Journal: EMBO J
Title: APP heterozygosity averts memory deficit in knockin mice expressing the Danish dementia BRI2 mutant.
Volume: 30
Issue: 12
Pages: 2501-9
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Publication
30096288 | J:330466
 
First Author: Aso E
Year: 2018
Journal: Biochem Pharmacol
Title: Genetic deletion of CB1 cannabinoid receptors exacerbates the Alzheimer-like symptoms in a transgenic animal model.
Volume: 157
Pages: 210-216
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Publication
18004725 | J:156291
First Author: Pihlaja R
Year: 2008
Journal: Glia
Title: Transplanted astrocytes internalize deposited beta-amyloid peptides in a transgenic mouse model of Alzheimer's disease.
Volume: 56
Issue: 2
Pages: 154-63
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Publication
25747037 | J:221130
 
First Author: Collins JM
Year: 2015
Journal: Exp Neurol
Title: The effect of focal brain injury on beta-amyloid plaque deposition, inflammation and synapses in the APP/PS1 mouse model of Alzheimer's disease.
Volume: 267
Pages: 219-29
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Publication
11337275 | J:78664
First Author: Jankowsky JL
Year: 2001
Journal: Biomol Eng
Title: Co-expression of multiple transgenes in mouse CNS: a comparison of strategies.
Volume: 17
Issue: 6
Pages: 157-65
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Publication
26779813 | J:233342
First Author: Baruch K
Year: 2016
Journal: Nat Med
Title: PD-1 immune checkpoint blockade reduces pathology and improves memory in mouse models of Alzheimer's disease.
Volume: 22
Issue: 2
Pages: 135-7
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Publication
34646380 | J:313643
First Author: Xu C
Year: 2021
Journal: Theranostics
Title: TNF-α-dependent neuronal necroptosis regulated in Alzheimer's disease by coordination of RIPK1-p62 complex with autophagic UVRAG.
Volume: 11
Issue: 19
Pages: 9452-9469
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Publication
37304021 | J:346937
 
First Author: Na D
Year: 2023
Journal: Front Neurosci
Title: Increased central auditory gain in 5xFAD Alzheimer's disease mice as an early biomarker candidate for Alzheimer's disease diagnosis.
Volume: 17
Pages: 1106570
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Publication
26489896 | J:338929
First Author: Yue W
Year: 2015
Journal: Stem Cell Reports
Title: ESC-Derived Basal Forebrain Cholinergic Neurons Ameliorate the Cognitive Symptoms Associated with Alzheimer's Disease in Mouse Models.
Volume: 5
Issue: 5
Pages: 776-790
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Publication
34080759 | J:311271
First Author: Zhang J
Year: 2021
Journal: Aging Cell
Title: Neuronal loss and microgliosis are restricted to the core of Aβ deposits in mouse models of Alzheimer's disease.
Volume: 20
Issue: 6
Pages: e13380
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Publication
28758999 | J:258017
First Author: Caccamo A
Year: 2017
Journal: Nat Neurosci
Title: Necroptosis activation in Alzheimer's disease.
Volume: 20
Issue: 9
Pages: 1236-1246
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Publication
25940071 | J:222768
First Author: Baruch K
Year: 2015
Journal: EMBO J
Title: Cerebral nitric oxide represses choroid plexus NFκB-dependent gateway activity for leukocyte trafficking.
Volume: 34
Issue: 13
Pages: 1816-28
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Publication
30742116 | J:277505
First Author: Cruz Hernández JC
Year: 2019
Journal: Nat Neurosci
Title: Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer's disease mouse models.
Volume: 22
Issue: 3
Pages: 413-420
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Publication
22975420 | J:194511
First Author: Yun SM
Year: 2013
Journal: Neurobiol Aging
Title: SUMO1 modulates Aβ generation via BACE1 accumulation.
Volume: 34
Issue: 3
Pages: 650-62
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Publication
37216506 | J:345103
First Author: Zhou GF
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: ARL6IP1 mediates small-molecule-induced alleviation of Alzheimer pathology through FXR1-dependent BACE1 translation initiation.
Volume: 120
Issue: 22
Pages: e2220148120
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Publication
38184014 | J:344408
 
First Author: Gharpure M
Year: 2024
Journal: Neurobiol Dis
Title: Alterations in Alzheimer's disease microglia transcriptome might be involved in bone pathophysiology.
Volume: 191
Pages: 106404
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Publication
20231476 | J:158919
First Author: Heneka MT
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine.
Volume: 107
Issue: 13
Pages: 6058-63
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Publication
33168021 | J:313490
First Author: Natunen T
Year: 2020
Journal: Mol Neurodegener
Title: Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaques.
Volume: 15
Issue: 1
Pages: 66
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Publication
19720431 | J:173732
First Author: Montgomery KS
Year: 2011
Journal: Neurobiol Aging
Title: Novel age-dependent learning deficits in a mouse model of Alzheimer's disease: implications for translational research.
Volume: 32
Issue: 7
Pages: 1273-85
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Publication
22522613 | J:196823
First Author: Zhang Y
Year: 2012
Journal: Diabetes
Title: Amyloid-β induces hepatic insulin resistance by activating JAK2/STAT3/SOCS-1 signaling pathway.
Volume: 61
Issue: 6
Pages: 1434-43
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Publication
32079659 | J:290161
 
First Author: Oudart M
Year: 2020
Journal: J Cell Sci
Title: AstroDot - a new method for studying the spatial distribution of mRNA in astrocytes.
Volume: 133
Issue: 7
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Publication
25706990 | J:226301
First Author: Brendel M
Year: 2015
Journal: PLoS One
Title: Cross-sectional comparison of small animal [18F]-florbetaben amyloid-PET between transgenic AD mouse models.
Volume: 10
Issue: 2
Pages: e0116678
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Publication
30127003 | J:265540
First Author: Tzeng TC
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Inflammasome-derived cytokine IL18 suppresses amyloid-induced seizures in Alzheimer-prone mice.
Volume: 115
Issue: 36
Pages: 9002-9007
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Publication
24210819 | J:205530
First Author: Michaud JP
Year: 2013
Journal: Cell Rep
Title: Real-time in vivo imaging reveals the ability of monocytes to clear vascular amyloid beta.
Volume: 5
Issue: 3
Pages: 646-53
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Publication
32514139 | J:298290
First Author: Poll S
Year: 2020
Journal: Nat Neurosci
Title: Memory trace interference impairs recall in a mouse model of Alzheimer's disease.
Volume: 23
Issue: 8
Pages: 952-958
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Publication
27234656 | J:231726
 
First Author: Peng W
Year: 2016
Journal: Neurobiol Dis
Title: Suppression of glymphatic fluid transport in a mouse model of Alzheimer's disease.
Volume: 93
Pages: 215-25
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Publication
21695208 | J:174789
First Author: Butler D
Year: 2011
Journal: PLoS One
Title: Protective effects of positive lysosomal modulation in Alzheimer's disease transgenic mouse models.
Volume: 6
Issue: 6
Pages: e20501
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Strain
MGI:5050419 | B6.Cg-Prnp<tm2Edin> Tg(APPswe,PSEN1dE9)85Dbo
Attribute String: congenic, mutant strain, targeted mutation
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Publication
31275228 | J:283146
 
First Author: Martin LJ
Year: 2019
Journal: Front Neurol
Title: Neonatal Brain Injury and Genetic Causes of Adult-Onset Neurodegenerative Disease in Mice Interact With Effects on Acute and Late Outcomes.
Volume: 10
Pages: 635
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Publication
31189938 | J:281589
First Author: Qin K
Year: 2019
Journal: Sci Rep
Title: "Dual Disease" TgAD/GSS mice exhibit enhanced Alzheimer's disease pathology and reveal PrPC-dependent secretion of Aβ.
Volume: 9
Issue: 1
Pages: 8524
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Publication
26089165 | J:226285
First Author: Janus C
Year: 2015
Journal: Neurobiol Aging
Title: Behavioral abnormalities in APPSwe/PS1dE9 mouse model of AD-like pathology: comparative analysis across multiple behavioral domains.
Volume: 36
Issue: 9
Pages: 2519-32
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Publication
25143627 | J:216162
First Author: Bae M
Year: 2014
Journal: J Neurosci
Title: Activation of TRPML1 clears intraneuronal Aβ in preclinical models of HIV infection.
Volume: 34
Issue: 34
Pages: 11485-503
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Publication
29038051 | J:255655
First Author: Nam KN
Year: 2018
Journal: Biochim Biophys Acta
Title: Integrated approach reveals diet, APOE genotype and sex affect immune response in APP mice.
Volume: 1864
Issue: 1
Pages: 152-161
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Publication
28275161 | J:240679
First Author: Liu CC
Year: 2017
Journal: J Neurosci
Title: Astrocytic LRP1 Mediates Brain Aβ Clearance and Impacts Amyloid Deposition.
Volume: 37
Issue: 15
Pages: 4023-4031
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Publication
34621153 | J:312676
 
First Author: Konings SC
Year: 2021
Journal: Front Neurosci
Title: Astrocytic and Neuronal Apolipoprotein E Isoforms Differentially Affect Neuronal Excitability.
Volume: 15
Pages: 734001
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Publication
19604604 | J:173735
First Author: Liu RM
Year: 2011
Journal: Neurobiol Aging
Title: Knockout of plasminogen activator inhibitor 1 gene reduces amyloid beta peptide burden in a mouse model of Alzheimer's disease.
Volume: 32
Issue: 6
Pages: 1079-89
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Publication
35173711 | J:325886
 
First Author: Lecordier S
Year: 2021
Journal: Front Immunol
Title: Multifocal Cerebral Microinfarcts Modulate Early Alzheimer's Disease Pathology in a Sex-Dependent Manner.
Volume: 12
Pages: 813536
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Publication
19200347 | J:149265
First Author: Zhang Q
Year: 2009
Journal: J Neurochem
Title: Role of caspase-3 in tau truncation at D421 is restricted in transgenic mouse models for tauopathies.
Volume: 109
Issue: 2
Pages: 476-84
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Publication
29862171 | J:280471
First Author: Dong ZZ
Year: 2018
Journal: Int J Ophthalmol
Title: Amyloid beta deposition related retinal pigment epithelium cell impairment and subretinal microglia activation in aged APPswePS1 transgenic mice.
Volume: 11
Issue: 5
Pages: 747-755
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Publication
22537779 | J:190171
First Author: Xu G
Year: 2012
Journal: Alzheimers Res Ther
Title: Reduction of low-density lipoprotein receptor-related protein (LRP1) in hippocampal neurons does not proportionately reduce, or otherwise alter, amyloid deposition in APPswe/PS1dE9 transgenic mice.
Volume: 4
Issue: 2
Pages: 12
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