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Search results 101 to 130 out of 130 for Rgs10

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Type Details Score
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
15593368 | -
First Author: Waugh JL
Year: 2005
Journal: J Comp Neurol
Title: Regional, cellular, and subcellular localization of RGS10 in rodent brain.
Volume: 481
Issue: 3
Pages: 299-313
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Publication
8774883 | -
First Author: Hunt TW
Year: 1996
Journal: Nature
Title: RGS10 is a selective activator of G alpha i GTPase activity.
Volume: 383
Issue: 6596
Pages: 175-7
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Allele
Rgs10<em1Smoc> | MGI:7292038
Name: regulator of G-protein signalling 10; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6476172 | C57BL/6-Rgs10<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Protein Domain
IPR037879 | RGS10_RGS
Type: Domain
Description: RGS (Regulator of G-protein Signaling) domain is an essential part of the RGS10 protein. RGS10 is a member of the RGS proteins family, a diverse group of multifunctional proteins that regulate cellular signaling events downstream of G-protein coupled receptors (GPCRs). RGS10 is one of the smallest proteins of the RGS family; its structure is little more than the RGS domain. As a major G-protein regulator, RGS domain containing proteins are involved in many crucial cellular processes such as regulation of intracellular trafficking, glial differentiation, embryonic axis formation, skeletal and muscle development, and cell migration during early embryogenesis [, ]. RGS10 belongs to the R12 RGS subfamily, which includes RGS12 and RGS14, all of which are highly selective for G-alpha-i1 over G-alpha-q []. RGS10 exists in 2 splice isoforms, RGS10A and RGS10B. Although the expression of RGS10 is ubiquitous, the highest levels are found in the brain and immune system []. RGS10A is expressed in osteoclasts and is a key component in the RANKL signaling mechanism for osteoclast differentiation [].
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Publication
12223533 | -
First Author: Hollinger S
Year: 2002
Journal: Pharmacol Rev
Title: Cellular regulation of RGS proteins: modulators and integrators of G protein signaling.
Volume: 54
Issue: 3
Pages: 527-59
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Publication
16687250 | -
First Author: Willars GB
Year: 2006
Journal: Semin Cell Dev Biol
Title: Mammalian RGS proteins: multifunctional regulators of cellular signalling.
Volume: 17
Issue: 3
Pages: 363-76
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Publication
22210881 | J:181706
First Author: Ma P
Year: 2012
Journal: Blood
Title: A newly identified complex of spinophilin and the tyrosine phosphatase, SHP-1, modulates platelet activation by regulating G protein-dependent signaling.
Volume: 119
Issue: 8
Pages: 1935-45
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Publication
35799794 | J:326517
 
First Author: Borrego A
Year: 2022
Journal: Front Immunol
Title: Pycard and BC017158 Candidate Genes of Irm1 Locus Modulate Inflammasome Activation for IL-1β Production.
Volume: 13
Pages: 899569
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Publication
17380122 | J:200411
First Author: Willard MD
Year: 2007
Journal: EMBO J
Title: Selective role for RGS12 as a Ras/Raf/MEK scaffold in nerve growth factor-mediated differentiation.
Volume: 26
Issue: 8
Pages: 2029-40
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Publication
16145674 | J:101032
First Author: Martin-McCaffrey L
Year: 2005
Journal: Dev Dyn
Title: Differential expression of regulator of G-protein signaling R12 subfamily members during mouse development.
Volume: 234
Issue: 2
Pages: 438-44
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Protein Domain
IPR037880 | RGS12_RGS
Type: Domain
Description: RGS (Regulator of G-protein Signaling) domain is an essential part of the RGS12 protein. RGS12 is a member of the RA/RGS subfamily of RGS proteins family, a diverse group of multifunctional proteins that regulate cellular signaling events downstream of G-protein coupled receptors (GPCRs). As a major G-protein regulator, RGS domain containing proteins are involved in many crucial cellular processes such as regulation of intracellular trafficking, glial differentiation, embryonic axis formation, skeletal and muscle development, and cell migration during early embryogenesis [, ]. RGS12 belongs to the R12 RGS subfamily, which includes RGS10 and RGS14, all of which are highly selective for G-alpha-i1 over G-alpha-q. RGS12 exist in multiple splice variants: RGS12s (short) contains the core RGS/RBD/GoLocodomains, while RGS12L (long) has additional N-terminal PDZ and PTB domains. RGS12 splice variants show distinct expression patterns, suggesting that they have discrete functions during mouse embryogenesis []. RGS12 also may play a critical role in coordinating Ras-dependent signals that are required for promoting and maintaining neuronal differentiation [].
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Protein
Q32MD7
Organism: Mus musculus/domesticus
Length: 181  
Fragment?: false
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Protein
Q3TTW9
Organism: Mus musculus/domesticus
Length: 499  
Fragment?: false
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Protein
D3Z0G6
Organism: Mus musculus/domesticus
Length: 733  
Fragment?: false
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Protein
D3Z0G7
Organism: Mus musculus/domesticus
Length: 793  
Fragment?: false
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Protein
E9Q1K7
Organism: Mus musculus/domesticus
Length: 723  
Fragment?: false
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Protein
Q9D677
Organism: Mus musculus/domesticus
Length: 723  
Fragment?: false
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Protein
D3Z0G5
Organism: Mus musculus/domesticus
Length: 803  
Fragment?: false
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Protein
Q8CGE9
Organism: Mus musculus/domesticus
Length: 1381  
Fragment?: false
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Protein
E9Q652
Organism: Mus musculus/domesticus
Length: 1451  
Fragment?: false
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