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Search results 1 to 75 out of 75 for Ints1

0.032s

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
26173 | INTS1
Type: gene
Organism: human
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Gene
790146 | INTS1
Type: gene
Organism: cattle
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Gene
100685475 | INTS1
Type: gene
Organism: dog, domestic
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Gene
416461 | INTS1
Type: gene
Organism: chicken
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Gene
562131 | ints1
Type: gene
Organism: zebrafish
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Gene
711947 | INTS1
Type: gene
Organism: macaque, rhesus
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Gene
100380131 | ints1
Type: gene
Organism: frog, western clawed
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Gene
107975668 | INTS1
Type: gene
Organism: chimpanzee
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Gene
288514 | Ints1
Type: gene
Organism: rat
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Protein Coding Gene
MGI:1915760 | Ints1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR038902 | INTS1
Type: Family
Description: INTS1 is a component of the Integrator (INT) complex. INT consists of at least 14 subunits and associates with the C-terminal domain of the largest subunit of the RNA polymerase II (RNAPII) and has a role in the regulation of gene expression and RNA processing. Besides mediating the co-transcriptional 3'-end processing of the U-rich small nuclear RNAs (UsnRNAs), INT also functions in RNAPII promoter proximal pause-release and in the processing of enhancer RNAs. Mutations in the INTS1 gene cause a severe neurodevelopmental syndrome [].
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Publication
28542170 | -
First Author: Oegema R
Year: 2017
Journal: PLoS Genet
Title: Human mutations in integrator complex subunits link transcriptome integrity to brain development.
Volume: 13
Issue: 5
Pages: e1006809
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Protein
Q0KK53
Organism: Mus musculus/domesticus
Length: 806  
Fragment?: true
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Protein
A0A0G2JFR3
Organism: Mus musculus/domesticus
Length: 137  
Fragment?: true
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Protein
A0A0G2JDG8
Organism: Mus musculus/domesticus
Length: 175  
Fragment?: true
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Protein
Q6P4S8
Organism: Mus musculus/domesticus
Length: 2195  
Fragment?: false
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Protein
A0A0G2JH17
Organism: Mus musculus/domesticus
Length: 2222  
Fragment?: false
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Protein
Q3U1N8
Organism: Mus musculus/domesticus
Length: 751  
Fragment?: false
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Protein
K3W4P2
Organism: Mus musculus/domesticus
Length: 2220  
Fragment?: false
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Protein Coding Gene
MGP_CAROLIEiJ_G0027938 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0030289 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0030258 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0030190 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0030275 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0029986 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1915760 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0030720 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0029391 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0029956 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0030106 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0030061 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0030192 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0030092 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0030760 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0029106 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0029465 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024510 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0028942 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:4442074
Assay Type: RT-PCR
Annotation Date: 2010-05-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:4442235
Age: embryonic day 0.5
Specimen Label: 1-cell
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4442074
Assay Type: RT-PCR
Annotation Date: 2010-05-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:4442235
Age: embryonic day 3.5
Specimen Label: Blastocyst
Detected: true
Specimen Num: 2
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Publication
- | J:76284
   
First Author: Strausberg R
Year: 2001
Journal: GenBank Submission
Title: Mus musculus, clone IMAGE: 3601115, mRNA, partial cds
Pages: BC010333
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Publication
16807365 | J:111319
First Author: Nakayama M
Year: 2006
Journal: FASEB J
Title: A gene-targeting approach for functional characterization of KIAA genes encoding extremely large proteins.
Volume: 20
Issue: 10
Pages: 1718-20
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Publication
17544522 | J:124808
First Author: Hata T
Year: 2007
Journal: Biochim Biophys Acta
Title: Targeted disruption of the murine large nuclear KIAA1440/Ints1 protein causes growth arrest in early blastocyst stage embryos and eventual apoptotic cell death.
Volume: 1773
Issue: 7
Pages: 1039-51
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Publication
- | J:175597
     
First Author: Overbeek PA
Year: 2011
Journal: MGI Direct Data Submission
Title: Direct Data Submission for Overbeek Lentiviral Transgenic Lines
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Publication
20562862 | J:161922
First Author: Tang T
Year: 2010
Journal: Nat Biotechnol
Title: A mouse knockout library for secreted and transmembrane proteins.
Volume: 28
Issue: 7
Pages: 749-55
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Publication
- | J:171883
     
First Author: Lexicon Genetics, Inc
Year: 2011
Journal: Database Download
Title: MGI download of Lexicon knockout data
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Publication
- | J:104881
     
First Author: The RIKEN BioResource Center
Year: 2006
Journal: Unpublished
Title: Information obtained from The RIKEN BioResource Center
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
- | J:73796
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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DO Term
DOID:0070346 | neurodevelopmental disorder with cataracts, poor growth, and dysmorphic facies
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