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Search results 1 to 100 out of 947 for Igf1r

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
3480 | IGF1R
Type: gene
Organism: human
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Gene
708227 | IGF1R
Type: gene
Organism: macaque, rhesus
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Gene
100329112 | igf1r
Type: gene
Organism: frog, western clawed
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Gene
key_33279 | IGF1R
Type: gene
Organism: pig, domestic
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Gene
25718 | Igf1r
Type: gene
Organism: rat
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Gene
453676 | IGF1R
Type: gene
Organism: chimpanzee
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Gene
442951 | IGF1R
Type: gene
Organism: dog, domestic
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Gene
281848 | IGF1R
Type: gene
Organism: cattle
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Gene
395889 | IGF1R
Type: gene
Organism: chicken
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Protein Coding Gene
MGI:96433 | Igf1r
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
Probe: MGI:6388764
Assay Type: Immunohistochemistry
Annotation Date: 2020-02-06
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3274722
Pattern: Scattered
Stage: TS22
Assay Id: MGI:6388789
Age: embryonic day 14.5
Image: 4 E14.5 Igf1r cKO
Note: Some residual positive expression.
Specimen Label: 4 E14.5 Igf1r cKO
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:6388764
Assay Type: Immunohistochemistry
Annotation Date: 2020-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1916022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6388789
Age: embryonic day 14.5
Image: 4 E14.5 Igf1r cKO
Note: Expressed normally in coronary blood vessel endothelium.
Specimen Label: 4 E14.5 Igf1r cKO
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:6388764
Assay Type: Immunohistochemistry
Annotation Date: 2020-02-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3274822
Stage: TS22
Assay Id: MGI:6388789
Age: embryonic day 14.5
Image: 4 E14.5 Igf1r cKO
Specimen Label: 4 E14.5 Igf1r cKO
Detected: false
Specimen Num: 8
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Gene
104472848 | IRAIN
Type: gene
Organism: human
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Gene
104564224 | LUNAR1
Type: gene
Organism: human
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Publication
37441495 | J:346964
 
First Author: Iwasaki K
Year: 2023
Journal: Front Endocrinol (Lausanne)
Title: Decreased IGF1R attenuates senescence and improves function in pancreatic β-cells.
Volume: 14
Pages: 1203534
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Publication
25238791 | J:221618
First Author: López IP
Year: 2015
Journal: Transgenic Res
Title: Differential organ phenotypes after postnatal Igf1r gene conditional deletion induced by tamoxifen in UBC-CreERT2; Igf1r fl/fl double transgenic mice.
Volume: 24
Issue: 2
Pages: 279-94
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Publication
25092896 | J:216071
First Author: Rota LM
Year: 2014
Journal: Cancer Res
Title: IGF1R inhibition in mammary epithelia promotes canonical Wnt signaling and Wnt1-driven tumors.
Volume: 74
Issue: 19
Pages: 5668-79
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GXD Expression
GXD Expression
Probe: MGI:6388766
Assay Type: Immunohistochemistry
Annotation Date: 2020-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6388798
Age: embryonic day 14.5
Image: 4 E14.5 Igf1r cKO
Note: Unchanged expression.
Specimen Label: 4 E14.5 Igf1r cKO
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:6388766
Assay Type: Immunohistochemistry
Annotation Date: 2020-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1916022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6388798
Age: embryonic day 14.5
Image: 4 E14.5 Igf1r cKO
Note: Unchanged expression. Expressed in coronary blood vessel endothelium.
Specimen Label: 4 E14.5 Igf1r cKO
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:6388759
Assay Type: Immunohistochemistry
Annotation Date: 2020-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6388799
Age: embryonic day 14.5
Image: 4 E14.5 Igf1r cKO
Specimen Label: 4 E14.5 Igf1r cKO
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:6388756
Assay Type: Immunohistochemistry
Annotation Date: 2020-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6388800
Age: embryonic day 14.5
Image: 4 E14.5 Igf1r cKO
Specimen Label: 4 E14.5 Igf1r cKO
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:6388766
Assay Type: Immunohistochemistry
Annotation Date: 2020-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6388798
Age: embryonic day 14.5
Image: 4 E14.5 Igf1r cKO
Note: Unchanged expression.
Specimen Label: 4 E14.5 Igf1r cKO
Detected: true
Specimen Num: 8
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Publication
23507142 | J:327178
First Author: Chen L
Year: 2013
Journal: FEBS Lett
Title: miR-16 inhibits cell proliferation by targeting IGF1R and the Raf1-MEK1/2-ERK1/2 pathway in osteosarcoma.
Volume: 587
Issue: 9
Pages: 1366-72
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Publication
25102325 | J:215379
 
First Author: Jakubik M
Year: 2014
Journal: Neurosci Lett
Title: Heterozygous Igf1r deletion does not ameliorate pathological features associated with polyglutamine-containing huntingtin fragment.
Volume: 580
Pages: 52-5
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Publication
22562956 | J:205389
First Author: Zumsteg A
Year: 2012
Journal: Mol Cancer Res
Title: Repression of malignant tumor progression upon pharmacologic IGF1R blockade in a mouse model of insulinoma.
Volume: 10
Issue: 6
Pages: 800-9
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Publication
38425784 | J:345885
 
First Author: Miller LR
Year: 2024
Journal: Front Aging Neurosci
Title: IGF1R deficiency in vascular smooth muscle cells impairs myogenic autoregulation and cognition in mice.
Volume: 16
Pages: 1320808
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Publication
30126838 | J:265837
First Author: Xu F
Year: 2018
Journal: J Cell Biol
Title: KIF1Bβ mutations detected in hereditary neuropathy impair IGF1R transport and axon growth.
Volume: 217
Issue: 10
Pages: 3480-3496
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Publication
36353242 | J:330962
 
First Author: Pérez-Matute P
Year: 2022
Journal: Front Endocrinol (Lausanne)
Title: IGF1R is a mediator of sex-specific metabolism in mice: Effects of age and high-fat diet.
Volume: 13
Pages: 1033208
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Publication
28655914 | J:241920
First Author: Piñeiro-Hermida S
Year: 2017
Journal: Sci Rep
Title: IGF1R deficiency attenuates acute inflammatory response in a bleomycin-induced lung injury mouse model.
Volume: 7
Issue: 1
Pages: 4290
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Publication
26862168 | J:230415
First Author: Triplett TA
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Endogenous dendritic cells from the tumor microenvironment support T-ALL growth via IGF1R activation.
Volume: 113
Issue: 8
Pages: E1016-25
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Publication
30354209 | J:285071
First Author: Sukhanov S
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: SM22α (Smooth Muscle Protein 22-α) Promoter-Driven IGF1R (Insulin-Like Growth Factor 1 Receptor) Deficiency Promotes Atherosclerosis.
Volume: 38
Issue: 10
Pages: 2306-2317
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Publication
19174523 | J:146290
First Author: Klinakis A
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Igf1r as a therapeutic target in a mouse model of basal-like breast cancer.
Volume: 106
Issue: 7
Pages: 2359-64
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Publication
32697974 | J:294899
First Author: Terry TT
Year: 2020
Journal: Dev Biol
Title: Mosaic Analysis with Double Markers reveals IGF1R function in granule cell progenitors during cerebellar development.
Volume: 465
Issue: 2
Pages: 130-143
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Publication
27861515 | J:241923
First Author: López IP
Year: 2016
Journal: PLoS One
Title: Involvement of Igf1r in Bronchiolar Epithelial Regeneration: Role during Repair Kinetics after Selective Club Cell Ablation.
Volume: 11
Issue: 11
Pages: e0166388
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Publication
22479204 | J:183847
First Author: Bedzhov I
Year: 2012
Journal: PLoS Genet
Title: Igf1r signaling is indispensable for preimplantation development and is activated via a novel function of E-cadherin.
Volume: 8
Issue: 3
Pages: e1002609
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Publication
28407051 | J:246789
First Author: Baumgarten SC
Year: 2017
Journal: Endocrinology
Title: IGF1R Expression in Ovarian Granulosa Cells Is Essential for Steroidogenesis, Follicle Survival, and Fertility in Female Mice.
Volume: 158
Issue: 7
Pages: 2309-2318
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GXD Expression
GXD Expression
   
Probe: MGI:6175307
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190592
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Igf1r
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6175307
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190592
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Igf1r
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6175307
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190592
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Igf1r
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6175307
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190592
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Igf1r
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6175307
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190592
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Igf1r
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6175307
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190592
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Igf1r
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6175307
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190592
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Igf1r
Detected: true
Specimen Num: 7
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Publication
37291945 | J:338243
First Author: Christova T
Year: 2023
Journal: EMBO Rep
Title: LTK and ALK promote neuronal polarity and cortical migration by inhibiting IGF1R activity.
Volume: 24
Issue: 7
Pages: e56937
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Publication
8806828 | J:34584
First Author: Ludwig T
Year: 1996
Journal: Dev Biol
Title: Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds.
Volume: 177
Issue: 2
Pages: 517-35
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Publication
21600935 | J:177752
First Author: Annenkov A
Year: 2011
Journal: Biochim Biophys Acta
Title: A chimeric receptor of the insulin-like growth factor receptor type 1 (IGFR1) and a single chain antibody specific to myelin oligodendrocyte glycoprotein activates the IGF1R signalling cascade in CG4 oligodendrocyte progenitors.
Volume: 1813
Issue: 8
Pages: 1428-37
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Publication
32046161 | J:297854
 
First Author: Geng H
Year: 2020
Journal: Int J Mol Sci
Title: MicroRNA 322 Aggravates Dexamethasone-Induced Muscle Atrophy by Targeting IGF1R and INSR.
Volume: 21
Issue: 3
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Publication
19568412 | J:271820
First Author: Linnerth NM
Year: 2009
Journal: Neoplasia
Title: Type I insulin-like growth factor receptor induces pulmonary tumorigenesis.
Volume: 11
Issue: 7
Pages: 672-82
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Publication
12370279 | J:79805
First Author: Xuan S
Year: 2002
Journal: J Clin Invest
Title: Defective insulin secretion in pancreatic beta cells lacking type 1 IGF receptor.
Volume: 110
Issue: 7
Pages: 1011-9
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Publication
16953219 | J:121069
First Author: Jones RA
Year: 2007
Journal: Oncogene
Title: Transgenic overexpression of IGF-IR disrupts mammary ductal morphogenesis and induces tumor formation.
Volume: 26
Issue: 11
Pages: 1636-44
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Publication
19377512 | J:151349
First Author: Jones RA
Year: 2009
Journal: Oncogene
Title: Reversibility and recurrence of IGF-IR-induced mammary tumors.
Volume: 28
Issue: 21
Pages: 2152-62
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Publication
25259518 | J:223493
First Author: Jones RA
Year: 2014
Journal: PLoS One
Title: IGF-IR mediated mammary tumorigenesis is enhanced during pubertal development.
Volume: 9
Issue: 9
Pages: e108781
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Publication
28351623 | J:250625
First Author: Thakur S
Year: 2017
Journal: Biochem Biophys Res Commun
Title: IGF-1 receptor haploinsufficiency leads to age-dependent development of metabolic syndrome.
Volume: 486
Issue: 4
Pages: 937-944
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Publication
12930811 | J:88198
First Author: Mason JL
Year: 2003
Journal: J Neurosci
Title: Insulin-like growth factor (IGF) signaling through type 1 IGF receptor plays an important role in remyelination.
Volume: 23
Issue: 20
Pages: 7710-8
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Publication
25825734 | J:220453
First Author: Shi Y
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Hedgehog signaling activates a positive feedback mechanism involving insulin-like growth factors to induce osteoblast differentiation.
Volume: 112
Issue: 15
Pages: 4678-83
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Publication
35931212 | J:327693
 
First Author: Yue S
Year: 2022
Journal: Neuropharmacology
Title: Insulin-like growth factor 1 regulates excitatory synaptic transmission in pyramidal neurons from adult prefrontal cortex.
Volume: 217
Pages: 109204
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Publication
30636901 | J:339430
First Author: Hwang DH
Year: 2018
Journal: Exp Neurobiol
Title: Insulin-like Growth Factor-1 Receptor Dictates Beneficial Effects of Treadmill Training by Regulating Survival and Migration of Neural Stem Cell Grafts in the Injured Spinal Cord.
Volume: 27
Issue: 6
Pages: 489-507
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Publication
31185266 | J:288970
 
First Author: Martin A
Year: 2019
Journal: Biochimie
Title: Fibroblast deficiency of insulin-like growth factor 1 receptor type 1 (IGF1R) impairs initial steps of murine pheochromocytoma development.
Volume: 163
Pages: 108-116
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Publication
19437543 | J:285880
First Author: Liu W
Year: 2009
Journal: J Neurosci Res
Title: Type 1 insulin-like growth factor receptor signaling is essential for the development of the hippocampal formation and dentate gyrus.
Volume: 87
Issue: 13
Pages: 2821-32
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Publication
22613471 | J:203165
First Author: Jenkins CR
Year: 2012
Journal: Exp Hematol
Title: IGF signaling contributes to malignant transformation of hematopoietic progenitors by the MLL-AF9 oncoprotein.
Volume: 40
Issue: 9
Pages: 715-723.e6
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Publication
25910049 | J:224631
First Author: Wu S
Year: 2015
Journal: Endocrinology
Title: Insulin-Like Growth Factor-Independent Effects of Growth Hormone on Growth Plate Chondrogenesis and Longitudinal Bone Growth.
Volume: 156
Issue: 7
Pages: 2541-51
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Publication
11923875 | J:76208
First Author: Kulkarni RN
Year: 2002
Journal: Nat Genet
Title: beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass.
Volume: 31
Issue: 1
Pages: 111-5
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Publication
8196606 | J:18499
First Author: Sell C
Year: 1994
Journal: Mol Cell Biol
Title: Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts.
Volume: 14
Issue: 6
Pages: 3604-12
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Publication
9850076 | J:51370
First Author: Liu X
Year: 1998
Journal: Cancer Res
Title: Inhibition of insulin-like growth factor I receptor expression in neuroblastoma cells induces the regression of established tumors in mice.
Volume: 58
Issue: 23
Pages: 5432-8
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Publication
31477557 | J:298393
First Author: Xing Y
Year: 2019
Journal: Mol Ther
Title: Long Noncoding RNA-Maternally Expressed Gene 3 Contributes to Hypoxic Pulmonary Hypertension.
Volume: 27
Issue: 12
Pages: 2166-2181
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Publication
35320720 | J:325492
First Author: Liu C
Year: 2022
Journal: Cell Rep
Title: Procr functions as a signaling receptor and is essential for the maintenance and self-renewal of mammary stem cells.
Volume: 38
Issue: 12
Pages: 110548
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Publication
2548293 | J:9941
First Author: Sundaresan S
Year: 1989
Journal: Somat Cell Mol Genet
Title: Insulin-like growth factor I receptor gene is concordant with c-Fes protooncogene and mouse chromosome 7 in somatic cell hybrids.
Volume: 15
Issue: 4
Pages: 373-6
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Publication
31562314 | J:287760
First Author: Li Q
Year: 2019
Journal: Nat Commun
Title: Homozygous receptors for insulin and not IGF-1 accelerate intimal hyperplasia in insulin resistance and diabetes.
Volume: 10
Issue: 1
Pages: 4427
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Publication
25981038 | J:228453
First Author: O'Neill BT
Year: 2015
Journal: Cell Rep
Title: Differential Role of Insulin/IGF-1 Receptor Signaling in Muscle Growth and Glucose Homeostasis.
Volume: 11
Issue: 8
Pages: 1220-35
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Publication
25246545 | J:216467
First Author: Boucher J
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Insulin and insulin-like growth factor 1 receptors are required for normal expression of imprinted genes.
Volume: 111
Issue: 40
Pages: 14512-7
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Publication
21139139 | J:185400
First Author: Boucher J
Year: 2010
Journal: Sci Signal
Title: A kinase-independent role for unoccupied insulin and IGF-1 receptors in the control of apoptosis.
Volume: 3
Issue: 151
Pages: ra87
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Publication
23250396 | J:260188
First Author: Evdokimova V
Year: 2012
Journal: Sci Signal
Title: IGFBP7 binds to the IGF-1 receptor and blocks its activation by insulin-like growth factors.
Volume: 5
Issue: 255
Pages: ra92
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Publication
26901525 | J:240159
First Author: Biggs BT
Year: 2016
Journal: PLoS One
Title: Insulin-Like Growth Factors Are Expressed in the Taste System, but Do Not Maintain Adult Taste Buds.
Volume: 11
Issue: 2
Pages: e0148315
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Publication
28173837 | J:314991
First Author: Ter Braak B
Year: 2017
Journal: Breast Cancer Res
Title: Insulin-like growth factor 1 receptor activation promotes mammary gland tumor development by increasing glycolysis and promoting biomass production.
Volume: 19
Issue: 1
Pages: 14
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Publication
37717026 | J:340770
First Author: Ishihara H
Year: 2023
Journal: Cell Death Dis
Title: Blocking insulin-like growth factor 1 receptor signaling pathway inhibits neuromuscular junction regeneration after botulinum toxin-A treatment.
Volume: 14
Issue: 9
Pages: 609
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Publication
37527036 | J:339037
First Author: Pan L
Year: 2023
Journal: Cell Rep
Title: IGFBPL1 is a master driver of microglia homeostasis and resolution of neuroinflammation in glaucoma and brain tauopathy.
Volume: 42
Issue: 8
Pages: 112889
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Publication
28402847 | J:251122
First Author: Spadaro O
Year: 2017
Journal: Cell Rep
Title: IGF1 Shapes Macrophage Activation in Response to Immunometabolic Challenge.
Volume: 19
Issue: 2
Pages: 225-234
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Publication
29272313 | J:254655
First Author: Piñeiro-Hermida S
Year: 2017
Journal: PLoS One
Title: Characterization of the acute inflammatory profile and resolution of airway inflammation after Igf1r-gene targeting in a murine model of HDM-induced asthma.
Volume: 12
Issue: 12
Pages: e0190159
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Publication
28207927 | J:241924
First Author: Piñeiro-Hermida S
Year: 2017
Journal: Allergy
Title: Attenuated airway hyperresponsiveness and mucus secretion in HDM-exposed Igf1r-deficient mice.
Volume: 72
Issue: 9
Pages: 1317-1326
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First Author: Liu JP
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