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Search results 2001 to 2100 out of 2420 for Gli3

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Type Details Score
Publication
First Author: Kawaguchi A
Year: 2008
Journal: Development
Title: Single-cell gene profiling defines differential progenitor subclasses in mammalian neurogenesis.
Volume: 135
Issue: 18
Pages: 3113-24
Protein
Organism: Mus musculus/domesticus
Length: 77  
Fragment?: false
Publication
First Author: Chen B
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.
Volume: 102
Issue: 47
Pages: 17184-9
Publication
First Author: Gurdziel K
Year: 2016
Journal: Dev Dyn
Title: Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun.
Volume: 245
Issue: 5
Pages: 614-26
Publication
First Author: Shimogori T
Year: 2010
Journal: Nat Neurosci
Title: A genomic atlas of mouse hypothalamic development.
Volume: 13
Issue: 6
Pages: 767-75
Publication
First Author: Shimizu H
Year: 2013
Journal: PLoS One
Title: The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.
Volume: 8
Issue: 10
Pages: e75754
Publication
First Author: Tang F
Year: 2011
Journal: PLoS One
Title: Deterministic and stochastic allele specific gene expression in single mouse blastomeres.
Volume: 6
Issue: 6
Pages: e21208
Publication      
First Author: Mammalian Functional Genomics Centre
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba
Publication        
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
Publication  
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
Publication
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
Publication
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Publication
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Allele  
Name: GLI-Kruppel family member GLI3; extra toes Jackson
Allele Type: Spontaneous
Publication
First Author: Sasaki H
Year: 1999
Journal: Development
Title: Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling.
Volume: 126
Issue: 17
Pages: 3915-24
Interaction Experiment
Description: Preaxial polydactyly caused by Gli3 haploinsufficiency is rescued by Zic3 loss of function in mice.
Genotype
Symbol: Gli3/Gli3
Background: involves: C3H * CD-1
Zygosity: hm
Has Mutant Allele: true
GXD Expression
Probe: MGI:5009297
Assay Type: RNA in situ
Annotation Date: 2011-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5009298
Age: embryonic day 14.5
Image: 6C
Note: Expression expands medially in the Gli3 mutant forebrain.
Specimen Label: 6C
Detected: true
Specimen Num: 7
Allele  
Name: Belly streak
Allele Type: Radiation induced
Publication
First Author: Caparrós-Martín JA
Year: 2013
Journal: Hum Mol Genet
Title: The ciliary Evc/Evc2 complex interacts with Smo and controls Hedgehog pathway activity in chondrocytes by regulating Sufu/Gli3 dissociation and Gli3 trafficking in primary cilia.
Volume: 22
Issue: 1
Pages: 124-39
Allele  
Name: GLI-Kruppel family member GLI3; targeted mutation 1, Ulrich Ruther
Allele Type: Targeted
DO Term
Interaction Experiment
Description: Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors.
Pathway
Genotype
Symbol: Bstk/Bstk<+>
Background: involves: C3H/HeH
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Bstk/Bstk
Background: involves: C3H/HeH
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Gli3/Gli3
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
DO Term
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 484  
Fragment?: false
Allele  
Name: GLI-Kruppel family member GLI3; anterior digit pattern deformity
Allele Type: Transgenic
Protein
Organism: Mus musculus/domesticus
Length: 93  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 142  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 93  
Fragment?: true
Allele  
Name: GLI-Kruppel family member GLI2; targeted mutation 2, Baolin Wang
Allele Type: Targeted
Allele  
Name: GLI-Kruppel family member GLI3; extra toes
Allele Type: Spontaneous
Strain
Attribute String: F1 hybrid, mutant stock
Allele  
Name: GLI-Kruppel family member GLI3; transgenic insertion
Allele Type: Transgenic
Genotype
Symbol: Gli3/Gli3
Background: involves: C57BL/6 * SJL
Zygosity: hm
Has Mutant Allele: true
Protein
Organism: Mus musculus/domesticus
Length: 235  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 447  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 92  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 85  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 245  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 270  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 244  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 435  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 538  
Fragment?: true
Protein Domain
Type: Family
Description: This entry includes a group of zinc finger transcription regulators, including GLI1-3 and GLIS1/3 from humans.GLI1-3 are central effectors of the Hedgehog (Hh) pathway in vertebrates [, ]. GLI1 is an obligatory activator, whereas GLI2 and GLI3 carry activator and repressor functions []. The full-length GLI3 form, after phosphorylation and nuclear translocation, acts as an activator (GLI3A) while its C-terminally truncated form acts as a repressor (GLI3R). GLI3 participates in the patterning and growth of many organs, including the central nervous system (CNS) and limbs [, , , , ].GLIS1/3 play key roles in the regulation of a number of physiological processes and have been implicated in several pathologies. Glis1-3 share a highly homologous zinc finger domain (ZFD) containing five Cys2-His2-type zinc finger (ZF) motifs with members of the Gli and Zic family [].
Publication
First Author: Pavletich NP
Year: 1993
Journal: Science
Title: Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers.
Volume: 261
Issue: 5129
Pages: 1701-7
Publication
First Author: Kinzler KW
Year: 1990
Journal: Mol Cell Biol
Title: The GLI gene encodes a nuclear protein which binds specific sequences in the human genome.
Volume: 10
Issue: 2
Pages: 634-42
Publication
First Author: Jiang J
Year: 2008
Journal: Dev Cell
Title: Hedgehog signaling in development and cancer.
Volume: 15
Issue: 6
Pages: 801-12
Publication
First Author: Lo HW
Year: 2009
Journal: Cancer Res
Title: A novel splice variant of GLI1 that promotes glioblastoma cell migration and invasion.
Volume: 69
Issue: 17
Pages: 6790-8
Protein Domain
Type: Family
Description: GLI1 (glioma-associated oncogene homologue 1) is a central effector of the Hedgehog (HH) pathway, a pathway that governs many developmental processes []. It is a member of the GLI family of transcription factors, which also includes GLI2 and GLI3 []. GLI1 is an obligatory activator, whereas GLI2 and GLI3 carry activator and repressor functions []. GLI1 is amplified in a subset of human tumours []. It contains five repeats of a zinc finger DNA-binding motif and binds DNA in a sequence-specific fashion [, ].
HT Experiment  
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
Strain
Attribute String: spontaneous mutation, mutant stock
Allele  
Name: GLI-Kruppel family member GLI2; targeted mutation 2.1, Baolin Wang
Allele Type: Targeted
Genotype
Symbol: Gli3/Gli3
Background: involves: C57BL/6J
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Gli3/Gli3<+>
Background: involves: C57BL/6J
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Gli3/Gli3<+>
Background: involves: 101/H * 129 * C3H/HeH * C57BL/6
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Gli3/Gli3
Background: involves: 101/H * 129 * C3H/HeH * C57BL/6 * CBA/H
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Gli3/Gli3
Background: involves: 101/H * C3H/HeH * CBA/H
Zygosity: hm
Has Mutant Allele: true