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Search results 101 to 200 out of 212 for Fermt3

0.036s
Type Details Score
GXD Expression      
Probe: MGI:3690856
Assay Type: RT-PCR
Annotation Date: 2006-12-18
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:3691188
Age: postnatal week 2
Specimen Label: Ovary
Detected: true
Specimen Num: 14
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1706828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692441
Age: postnatal adult
Image: JAX_1305960
Specimen Label: JAX_1305960
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3690859
Assay Type: RNA in situ
Annotation Date: 2006-12-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:3690904
Age: embryonic day 15.0
Specimen Label: 4H
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:1803007
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4824828
Age: embryonic day 14.5
Image: euxassay_002482_13
Specimen Label: euxassay_002482_13
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1803007
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4824828
Age: embryonic day 14.5
Image: euxassay_002482_14
Specimen Label: euxassay_002482_14
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:1803007
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4824828
Age: embryonic day 14.5
Image: euxassay_002482_15
Specimen Label: euxassay_002482_15
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:1803007
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4824828
Age: embryonic day 14.5
Image: euxassay_002482_16
Specimen Label: euxassay_002482_16
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:1803007
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4824828
Age: embryonic day 14.5
Image: euxassay_002482_17
Specimen Label: euxassay_002482_17
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:1803007
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4824828
Age: embryonic day 14.5
Image: euxassay_002482_18
Specimen Label: euxassay_002482_18
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:3690859
Assay Type: RNA in situ
Annotation Date: 2006-12-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684620
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:3690904
Age: embryonic day 12.0
Note: Expression was particularly strong in large multinucleated cells, most likely representing megakaryocytes.
Specimen Label: 4B
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3690859
Assay Type: RNA in situ
Annotation Date: 2006-12-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684621
Pattern: Non-Uniform
Stage: TS21
Assay Id: MGI:3690904
Age: embryonic day 13.0
Note: Expression was particularly strong in large multinucleated cells, most likely representing megakaryocytes.
Specimen Label: 4D
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3690859
Assay Type: RNA in situ
Annotation Date: 2006-12-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Non-Uniform
Stage: TS23
Assay Id: MGI:3690904
Age: embryonic day 15.0
Note: Expression was particularly strong in large multinucleated cells, most likely representing megakaryocytes.
Specimen Label: 4F
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3690865
Assay Type: Immunohistochemistry
Annotation Date: 2006-12-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684622
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:3690912
Age: embryonic day 14.5
Note: Expression was detected in the liver with particularly high signals in megakaryocytes.
Specimen Label: 5E, 5E'
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692441
Age: postnatal adult
Image: JAX_1305961
Specimen Label: JAX_1305961
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:1803007
Assay Type: RNA in situ
Annotation Date: 2024-01-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7576142
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:1803007
Assay Type: RNA in situ
Annotation Date: 2024-01-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7576142
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:1803007
Assay Type: RNA in situ
Annotation Date: 2024-01-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3518622
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7576142
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692441
Age: postnatal adult
Image: JAX_1305959
Specimen Label: JAX_1305959
Detected: true
Specimen Num: 1
Publication
First Author: Spinelli SL
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: A functional homolog of a yeast tRNA splicing enzyme is conserved in higher eukaryotes and in Escherichia coli.
Volume: 95
Issue: 24
Pages: 14136-41
Publication
First Author: Yan Y
Year: 2019
Journal: Aging (Albany NY)
Title: Kindlin-3 in platelets and myeloid cells differentially regulates deep vein thrombosis in mice.
Volume: 11
Issue: 17
Pages: 6951-6959
Publication
First Author: Hidalgo A
Year: 2009
Journal: Nat Med
Title: When integrins fail to integrate.
Volume: 15
Issue: 3
Pages: 249-50
Publication
First Author: Shiratori T
Year: 2018
Journal: J Immunol
Title: IL-1β Induces Pathologically Activated Osteoclasts Bearing Extremely High Levels of Resorbing Activity: A Possible Pathological Subpopulation of Osteoclasts, Accompanied by Suppressed Expression of Kindlin-3 and Talin-1.
Volume: 200
Issue: 1
Pages: 218-228
Publication
First Author: Ussar S
Year: 2006
Journal: Exp Cell Res
Title: The Kindlins: subcellular localization and expression during murine development.
Volume: 312
Issue: 16
Pages: 3142-51
Publication
First Author: Moser M
Year: 2009
Journal: Nat Med
Title: Kindlin-3 is required for beta2 integrin-mediated leukocyte adhesion to endothelial cells.
Volume: 15
Issue: 3
Pages: 300-5
Publication
First Author: Petzold T
Year: 2013
Journal: Blood
Title: β1 integrin-mediated signals are required for platelet granule secretion and hemostasis in mouse.
Volume: 122
Issue: 15
Pages: 2723-31
Publication
First Author: Härzschel A
Year: 2022
Journal: J Leukoc Biol
Title: Kindlin-3 maintains marginal zone B cells but confines follicular B cell activation and differentiation.
Volume: 111
Issue: 4
Pages: 745-758
Publication
First Author: Guo L
Year: 2019
Journal: Nat Commun
Title: Kindlin-2 links mechano-environment to proline synthesis and tumor growth.
Volume: 10
Issue: 1
Pages: 845
Publication
First Author: Klapproth S
Year: 2019
Journal: J Cell Biol
Title: A kindlin-3-leupaxin-paxillin signaling pathway regulates podosome stability.
Volume: 218
Issue: 10
Pages: 3436-3454
Publication
First Author: Marcovecchio PM
Year: 2020
Journal: J Leukoc Biol
Title: Frontline Science: Kindlin-3 is essential for patrolling and phagocytosis functions of nonclassical monocytes during metastatic cancer surveillance.
Volume: 107
Issue: 6
Pages: 883-892
Publication
First Author: Krüger M
Year: 2008
Journal: Cell
Title: SILAC mouse for quantitative proteomics uncovers kindlin-3 as an essential factor for red blood cell function.
Volume: 134
Issue: 2
Pages: 353-64
Publication
First Author: Klapproth S
Year: 2015
Journal: Blood
Title: Minimal amounts of kindlin-3 suffice for basal platelet and leukocyte functions in mice.
Volume: 126
Issue: 24
Pages: 2592-600
Publication
First Author: Wilson ZS
Year: 2017
Journal: Am J Respir Cell Mol Biol
Title: Activated β2 Integrins Restrict Neutrophil Recruitment during Murine Acute Pseudomonal Pneumonia.
Volume: 56
Issue: 5
Pages: 620-627
Publication
First Author: Fischer A
Year: 2022
Journal: Nat Immunol
Title: Neutrophils direct preexisting matrix to initiate repair in damaged tissues.
Volume: 23
Issue: 4
Pages: 518-531
Publication
First Author: Dixit N
Year: 2012
Journal: J Immunol
Title: Leukocyte function antigen-1, kindlin-3, and calcium flux orchestrate neutrophil recruitment during inflammation.
Volume: 189
Issue: 12
Pages: 5954-64
Publication
First Author: Xu Z
Year: 2014
Journal: Arterioscler Thromb Vasc Biol
Title: Direct interaction of kindlin-3 with integrin αIIbβ3 in platelets is required for supporting arterial thrombosis in mice.
Volume: 34
Issue: 9
Pages: 1961-7
Publication
First Author: Moser M
Year: 2008
Journal: Nat Med
Title: Kindlin-3 is essential for integrin activation and platelet aggregation.
Volume: 14
Issue: 3
Pages: 325-30
Publication    
First Author: Moretti FA
Year: 2018
Journal: Elife
Title: Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus.
Volume: 7
Publication
First Author: Marx C
Year: 2019
Journal: Blood
Title: Eosinophil-platelet interactions promote atherosclerosis and stabilize thrombosis with eosinophil extracellular traps.
Volume: 134
Issue: 21
Pages: 1859-1872
Publication
First Author: Kasirer-Friede A
Year: 2014
Journal: Blood
Title: ADAP interactions with talin and kindlin promote platelet integrin αIIbβ3 activation and stable fibrinogen binding.
Volume: 123
Issue: 20
Pages: 3156-65
Publication
First Author: Uhrin P
Year: 2010
Journal: Blood
Title: Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation.
Volume: 115
Issue: 19
Pages: 3997-4005
Publication
First Author: Schmidt S
Year: 2011
Journal: J Cell Biol
Title: Kindlin-3-mediated signaling from multiple integrin classes is required for osteoclast-mediated bone resorption.
Volume: 192
Issue: 5
Pages: 883-97
Publication
First Author: Kamioka Y
Year: 2023
Journal: Cell Rep
Title: Distinct bidirectional regulation of LFA1 and α4β7 by Rap1 and integrin adaptors in T cells under shear flow.
Volume: 42
Issue: 6
Pages: 112580
Publication  
First Author: Wu C
Year: 2015
Journal: Nat Commun
Title: Kindlin-2 controls TGF-β signalling and Sox9 expression to regulate chondrogenesis.
Volume: 6
Pages: 7531
Publication
First Author: Abdallah BM
Year: 2011
Journal: J Bone Miner Res
Title: DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice.
Volume: 26
Issue: 7
Pages: 1457-71
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Allele
Name: fermitin family member 3; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: fermitin family member 3; targeted mutation 1, Reinhard Fassler
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: RAS, guanyl releasing protein 2; targeted mutation 1, Ann M Graybiel
Allele Type: Targeted
Attribute String: Null/knockout
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Genotype
Symbol: Rasgrp2/Rasgrp2
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Fermt3/Fermt3
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
DO Term
Allele
Name: fermitin family member 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Allele  
Name: integrin beta 2; targeted mutation 1.1, TaconicArtemis
Allele Type: Targeted
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Publication
First Author: Meakin PJ
Year: 2015
Journal: PLoS One
Title: Mice Lacking beta2-Integrin Function Remain Glucose Tolerant in Spite of Insulin Resistance, Neutrophil Infiltration and Inflammation.
Volume: 10
Issue: 9
Pages: e0138872
Publication
First Author: Savinko TS
Year: 2015
Journal: J Invest Dermatol
Title: Functional Beta2-Integrins Restrict Skin Inflammation In Vivo.
Volume: 135
Issue: 9
Pages: 2249-2257
Genotype
Symbol: Itgb2/Itgb2
Background: involves: C57BL/6NTac
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Weinstein EJ
Year: 2003
Journal: Biochim Biophys Acta
Title: URP1: a member of a novel family of PH and FERM domain-containing membrane-associated proteins is significantly over-expressed in lung and colon carcinomas.
Volume: 1637
Issue: 3
Pages: 207-16
Publication
First Author: Liu J
Year: 2011
Journal: J Biol Chem
Title: Structural basis of phosphoinositide binding to kindlin-2 protein pleckstrin homology domain in regulating integrin activation.
Volume: 286
Issue: 50
Pages: 43334-42
Publication  
First Author: Rozario T
Year: 2014
Journal: Mech Dev
Title: Diverse functions of kindlin/fermitin proteins during embryonic development in Xenopus laevis.
Volume: 133
Pages: 203-17
Publication
First Author: Canning CA
Year: 2011
Journal: Dev Dyn
Title: Developmental expression of the fermitin/kindlin gene family in Xenopus laevis embryos.
Volume: 240
Issue: 8
Pages: 1958-63
Publication
First Author: Ye F
Year: 2014
Journal: Front Med
Title: Talin and kindlin: the one-two punch in integrin activation.
Volume: 8
Issue: 1
Pages: 6-16
Protein
Organism: Mus musculus/domesticus
Length: 266  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 93  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 72  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 258  
Fragment?: true