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Search results 201 to 294 out of 294 for Eif2ak3

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Type Details Score
Publication
25113558 | J:224338
First Author: Meares GP
Year: 2014
Journal: Mol Cell Biol
Title: PERK-dependent activation of JAK1 and STAT3 contributes to endoplasmic reticulum stress-induced inflammation.
Volume: 34
Issue: 20
Pages: 3911-25
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Publication
29653943 | J:263884
First Author: Kang X
Year: 2018
Journal: J Biol Chem
Title: Sirtuin-1 (SIRT1) stimulates growth-plate chondrogenesis by attenuating the PERK-eIF-2α-CHOP pathway in the unfolded protein response.
Volume: 293
Issue: 22
Pages: 8614-8625
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Publication
16176978 | J:107108
First Author: Hamanaka RB
Year: 2005
Journal: Mol Biol Cell
Title: PERK and GCN2 contribute to eIF2alpha phosphorylation and cell cycle arrest after activation of the unfolded protein response pathway.
Volume: 16
Issue: 12
Pages: 5493-501
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Publication
20660158 | J:182847
First Author: Muaddi H
Year: 2010
Journal: Mol Biol Cell
Title: Phosphorylation of eIF2α at serine 51 is an important determinant of cell survival and adaptation to glucose deficiency.
Volume: 21
Issue: 18
Pages: 3220-31
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Publication
14729979 | J:124910
First Author: Jiang HY
Year: 2004
Journal: Mol Cell Biol
Title: Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response.
Volume: 24
Issue: 3
Pages: 1365-77
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Publication
21385877 | J:171119
First Author: Peña J
Year: 2011
Journal: J Biol Chem
Title: Dengue virus modulates the unfolded protein response in a time-dependent manner.
Volume: 286
Issue: 16
Pages: 14226-36
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Publication
26106220 | J:259821
First Author: Kanekura K
Year: 2015
Journal: Sci Signal
Title: IRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditions.
Volume: 8
Issue: 382
Pages: ra62
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Publication
23144714 | J:225075
First Author: Mann MJ
Year: 2012
Journal: PLoS One
Title: UPR-induced resistance to etoposide is downstream of PERK and independent of changes in topoisomerase IIα levels.
Volume: 7
Issue: 10
Pages: e47931
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Publication
27698114 | J:238493
First Author: Khoutorsky A
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: eIF2α phosphorylation controls thermal nociception.
Volume: 113
Issue: 42
Pages: 11949-11954
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Publication
31543404 | J:283399
First Author: Chen S
Year: 2019
Journal: Cell Metab
Title: Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction.
Volume: 30
Issue: 6
Pages: 1141-1151.e5
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Publication
27977682 | J:238714
First Author: Pytel D
Year: 2016
Journal: PLoS Genet
Title: PERK Is a Haploinsufficient Tumor Suppressor: Gene Dose Determines Tumor-Suppressive Versus Tumor Promoting Properties of PERK in Melanoma.
Volume: 12
Issue: 12
Pages: e1006518
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Publication
28724791 | J:290198
 
First Author: Cai Y
Year: 2017
Journal: JCI Insight
Title: Mitochondrial DNA-enriched microparticles promote acute-on-chronic alcoholic neutrophilia and hepatotoxicity.
Volume: 2
Issue: 14
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Publication
28440222 | J:253375
   
First Author: Larhammar M
Year: 2017
Journal: Elife
Title: Dual leucine zipper kinase-dependent PERK activation contributes to neuronal degeneration following insult.
Volume: 6
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Publication
33879538 | J:307142
First Author: Sidoli M
Year: 2021
Journal: J Neurosci
Title: Calcineurin Activity Is Increased in Charcot-Marie-Tooth 1B Demyelinating Neuropathy.
Volume: 41
Issue: 20
Pages: 4536-4548
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Publication
25183803 | J:216137
First Author: McAlpine CS
Year: 2014
Journal: J Lipid Res
Title: Protein kinase R-like endoplasmic reticulum kinase and glycogen synthase kinase-3α/β regulate foam cell formation.
Volume: 55
Issue: 11
Pages: 2320-33
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Publication
16352659 | J:105342
First Author: Huang G
Year: 2006
Journal: J Cell Sci
Title: ER stress disrupts Ca2+-signaling complexes and Ca2+ regulation in secretory and muscle cells from PERK-knockout mice.
Volume: 119
Issue: Pt 1
Pages: 153-61
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Publication
23152784 | J:195351
First Author: Zhang Y
Year: 2012
Journal: PLoS One
Title: Transcriptional regulation of the Ufm1 conjugation system in response to disturbance of the endoplasmic reticulum homeostasis and inhibition of vesicle trafficking.
Volume: 7
Issue: 11
Pages: e48587
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Publication
20924113 | J:165561
First Author: Papadakis AI
Year: 2010
Journal: Cancer Res
Title: eIF2{alpha} Kinase PKR modulates the hypoxic response by Stat3-dependent transcriptional suppression of HIF-1{alpha}.
Volume: 70
Issue: 20
Pages: 7820-9
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Publication
21044701 | J:168632
First Author: Firtina Z
Year: 2011
Journal: Gene Expr Patterns
Title: Unfolded Protein Response (UPR) is activated during normal lens development.
Volume: 11
Issue: 1-2
Pages: 135-43
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Publication
23042294 | J:189071
First Author: Upton JP
Year: 2012
Journal: Science
Title: IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2.
Volume: 338
Issue: 6108
Pages: 818-22
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Publication
22773666 | J:208516
First Author: Cunha DA
Year: 2012
Journal: Diabetes
Title: Death protein 5 and p53-upregulated modulator of apoptosis mediate the endoplasmic reticulum stress-mitochondrial dialog triggering lipotoxic rodent and human β-cell apoptosis.
Volume: 61
Issue: 11
Pages: 2763-75
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Publication
32758541 | J:294896
 
First Author: Aryal YP
Year: 2020
Journal: Gene Expr Patterns
Title: Stage-specific expression patterns of ER stress-related molecules in mice molars: Implications for tooth development.
Volume: 37
Pages: 119130
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Publication
34168130 | J:341523
First Author: Vanhoutte D
Year: 2021
Journal: Nat Commun
Title: Thbs1 induces lethal cardiac atrophy through PERK-ATF4 regulated autophagy.
Volume: 12
Issue: 1
Pages: 3928
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Publication
32294407 | J:288457
First Author: Mohamed E
Year: 2020
Journal: Immunity
Title: The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling.
Volume: 52
Issue: 4
Pages: 668-682.e7
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Publication
33361822 | J:305864
First Author: Kalish BT
Year: 2021
Journal: Nat Neurosci
Title: Maternal immune activation in mice disrupts proteostasis in the fetal brain.
Volume: 24
Issue: 2
Pages: 204-213
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Publication
11747369 | J:73377
First Author: Wahlin KJ
Year: 2001
Journal: Exp Eye Res
Title: Neurotrophic signaling in normal and degenerating rodent retinas.
Volume: 73
Issue: 5
Pages: 693-701
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Publication
19911006 | J:171795
First Author: Ishigaki S
Year: 2010
Journal: Cell Death Differ
Title: AATF mediates an antiapoptotic effect of the unfolded protein response through transcriptional regulation of AKT1.
Volume: 17
Issue: 5
Pages: 774-86
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Publication
14517290 | J:85958
First Author: Cullinan SB
Year: 2003
Journal: Mol Cell Biol
Title: Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival.
Volume: 23
Issue: 20
Pages: 7198-209
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Publication
12388085 | J:82058
First Author: Kimball SR
Year: 2003
Journal: Am J Physiol Cell Physiol
Title: Mammalian stress granules represent sites of accumulation of stalled translation initiation complexes.
Volume: 284
Issue: 2
Pages: C273-84
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Publication
34124052 | J:308694
 
First Author: Tan YY
Year: 2021
Journal: Front Cell Dev Biol
Title: PERK Signaling Controls Myoblast Differentiation by Regulating MicroRNA Networks.
Volume: 9
Pages: 670435
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Publication
19805353 | J:153222
First Author: Iwawaki T
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability.
Volume: 106
Issue: 39
Pages: 16657-62
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Publication
27130031 | J:315123
 
First Author: Zhong J
Year: 2016
Journal: Free Radic Biol Med
Title: Superoxide dismutase 2 overexpression alleviates maternal diabetes-induced neural tube defects, restores mitochondrial function and suppresses cellular stress in diabetic embryopathy.
Volume: 96
Pages: 234-44
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Publication
36150390 | J:330167
First Author: Mandula JK
Year: 2022
Journal: Cancer Cell
Title: Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses.
Volume: 40
Issue: 10
Pages: 1145-1160.e9
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Publication
22961085 | J:208480
First Author: Li X
Year: 2013
Journal: Diabetes
Title: c-Jun NH2-terminal kinase 1/2 and endoplasmic reticulum stress as interdependent and reciprocal causation in diabetic embryopathy.
Volume: 62
Issue: 2
Pages: 599-608
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Publication
18297134 | J:132695
First Author: Wilding Crawford L
Year: 2008
Journal: PLoS One
Title: Gene expression profiling of a mouse model of pancreatic islet dysmorphogenesis.
Volume: 3
Issue: 2
Pages: e1611
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Publication
31436800 | J:281567
First Author: Ariyasu D
Year: 2019
Journal: Endocrinology
Title: Decreased Activity of the Ghrhr and Gh Promoters Causes Dominantly Inherited GH Deficiency in Humanized GH1 Mouse Models.
Volume: 160
Issue: 11
Pages: 2673-2691
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Publication
29056340 | J:249176
First Author: Moretti J
Year: 2017
Journal: Cell
Title: STING Senses Microbial Viability to Orchestrate Stress-Mediated Autophagy of the Endoplasmic Reticulum.
Volume: 171
Issue: 4
Pages: 809-823.e13
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Publication
19858219 | J:158314
First Author: Firtina Z
Year: 2009
Journal: J Biol Chem
Title: Abnormal expression of collagen IV in lens activates unfolded protein response resulting in cataract.
Volume: 284
Issue: 51
Pages: 35872-84
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Publication
30963569 | J:291194
First Author: Aryal YP
Year: 2019
Journal: J Cell Physiol
Title: An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar.
Volume: 234
Issue: 11
Pages: 20354-20365
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Publication
33060561 | J:313943
First Author: Cao S
Year: 2020
Journal: Cell Death Dis
Title: Restoring BMP4 expression in vascular endothelial progenitors ameliorates maternal diabetes-induced apoptosis and neural tube defects.
Volume: 11
Issue: 10
Pages: 859
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Publication
30635284 | J:272566
 
First Author: Yang R
Year: 2019
Journal: Development
Title: CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development.
Volume: 146
Issue: 2
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Publication
19633360 | J:157050
First Author: Bojanic DD
Year: 2010
Journal: J Lipid Res
Title: Differential expression and function of ABCG1 and ABCG4 during development and aging.
Volume: 51
Issue: 1
Pages: 169-81
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Publication
26651292 | J:240003
First Author: Laguesse S
Year: 2015
Journal: Dev Cell
Title: A Dynamic Unfolded Protein Response Contributes to the Control of Cortical Neurogenesis.
Volume: 35
Issue: 5
Pages: 553-67
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Publication
27416896 | J:240829
 
First Author: Jiang M
Year: 2016
Journal: Nat Commun
Title: Regulation of PERK-eIF2α signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes.
Volume: 7
Pages: 12185
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Publication
27106802 | J:253948
 
First Author: Magarin M
Year: 2016
Journal: J Mol Cell Cardiol
Title: Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stress.
Volume: 97
Pages: 1-14
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Publication
30655546 | J:270211
First Author: Yang P
Year: 2019
Journal: Nat Commun
Title: Tip60- and sirtuin 2-regulated MARCKS acetylation and phosphorylation are required for diabetic embryopathy.
Volume: 10
Issue: 1
Pages: 282
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Publication
19139267 | J:146172
First Author: Wang X
Year: 2009
Journal: J Cell Biol
Title: Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant mice.
Volume: 184
Issue: 1
Pages: 143-58
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Publication
17540781 | J:123644
First Author: Roma G
Year: 2007
Journal: Genome Res
Title: A novel view of the transcriptome revealed from gene trapping in mouse embryonic stem cells.
Volume: 17
Issue: 7
Pages: 1051-60
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Publication
26173459 | J:226104
First Author: Wang F
Year: 2015
Journal: Am J Physiol Endocrinol Metab
Title: ASK1 mediates the teratogenicity of diabetes in the developing heart by inducing ER stress and inhibiting critical factors essential for cardiac development.
Volume: 309
Issue: 5
Pages: E487-99
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Publication
36841836 | J:333724
First Author: Park EJ
Year: 2023
Journal: Nat Commun
Title: Ssu72 phosphatase is essential for thermogenic adaptation by regulating cytosolic translation.
Volume: 14
Issue: 1
Pages: 1097
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
18554416 | J:139177
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Eif2ak3<em1Smoc> | MGI:7289463
Name: eukaryotic translation initiation factor 2 alpha kinase 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:6475188 | C57BL/6J-Eif2ak3<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Tg(Plp1-Eif2ak3*)18Pop | MGI:6116281
Name: transgene insertion 18, Brian Popko
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence
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Strain
MGI:6116282 | C57BL/6J-Tg(Plp1-Eif2ak3*)18Pop
Attribute String: coisogenic, mutant strain, transgenic
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Strain
MGI:6153126 | C57BL/6J-Tg(Plp1-Eif2ak3*)18Pop/J
Attribute String: coisogenic, mutant strain, transgenic
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Publication
25186761 | J:216298
First Author: Lin Y
Year: 2014
Journal: J Neurosci
Title: Impaired eukaryotic translation initiation factor 2B activity specifically in oligodendrocytes reproduces the pathology of vanishing white matter disease in mice.
Volume: 34
Issue: 36
Pages: 12182-91
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Genotype
Genotype
Symbol: Tg(Plp1-Eif2ak3*)18Pop/?
Background: C57BL/6J-Tg(Plp1-Eif2ak3*)18Pop
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Plp1-Eif2ak3*)18Pop/Tg(Plp1-Eif2ak3*)18Pop
Background: C57BL/6J-Tg(Plp1-Eif2ak3*)18Pop
Zygosity: hm
Has Mutant Allele: true
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Publication
30709400 | J:277711
First Author: Yue Y
Year: 2019
Journal: J Neuroinflammation
Title: Oligodendrocyte-specific ATF4 inactivation does not influence the development of EAE.
Volume: 16
Issue: 1
Pages: 23
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