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Search results 1 to 100 out of 178 for Tnfrsf9

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Category: Publication
Type Details Score
Publication
First Author: Forsberg MH
Year: 2019
Journal: Sci Rep
Title: Combined congenic mapping and nuclease-based gene targeting for studying allele-specific effects of Tnfrsf9 within the Idd9.3 autoimmune diabetes locus.
Volume: 9
Issue: 1
Pages: 4316
Publication
First Author: Chen YG
Year: 2014
Journal: Diabetes
Title: Gene targeting in NOD mouse embryos using zinc-finger nucleases.
Volume: 63
Issue: 1
Pages: 68-74
Publication
First Author: Freeman ZT
Year: 2020
Journal: J Clin Invest
Title: A conserved intratumoral regulatory T cell signature identifies 4-1BB as a pan-cancer target.
Volume: 130
Issue: 3
Pages: 1405-1416
Publication
First Author: Kwon BS
Year: 1994
Journal: J Immunol
Title: Genomic organization and chromosomal localization of the T-cell antigen 4-1BB.
Volume: 152
Issue: 5
Pages: 2256-62
Publication
First Author: Narazaki H
Year: 2010
Journal: Blood
Title: CD137 agonist antibody prevents cancer recurrence: contribution of CD137 on both hematopoietic and nonhematopoietic cells.
Volume: 115
Issue: 10
Pages: 1941-8
Publication
First Author: Lee SW
Year: 2006
Journal: J Immunol
Title: Functional dichotomy between OX40 and 4-1BB in modulating effector CD8 T cell responses.
Volume: 177
Issue: 7
Pages: 4464-72
Publication
First Author: Cui J
Year: 1997
Journal: Science
Title: Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors.
Volume: 278
Issue: 5343
Pages: 1623-6
Publication
First Author: Cannons JL
Year: 2005
Journal: J Autoimmun
Title: Genetic and functional association of the immune signaling molecule 4-1BB (CD137/TNFRSF9) with type 1 diabetes.
Volume: 25
Issue: 1
Pages: 13-20
Publication
First Author: Wang J
Year: 2010
Journal: J Immunol
Title: CD137-mediated pathogenesis from chronic hepatitis to hepatocellular carcinoma in hepatitis B virus-transgenic mice.
Volume: 185
Issue: 12
Pages: 7654-62
Publication
First Author: Palazón A
Year: 2011
Journal: Cancer Res
Title: Agonist anti-CD137 mAb act on tumor endothelial cells to enhance recruitment of activated T lymphocytes.
Volume: 71
Issue: 3
Pages: 801-11
Publication
First Author: Lee SW
Year: 2012
Journal: J Immunol
Title: Cutting edge: 4-1BB controls regulatory activity in dendritic cells through promoting optimal expression of retinal dehydrogenase.
Volume: 189
Issue: 6
Pages: 2697-701
Publication
First Author: Lee SW
Year: 2005
Journal: J Immunol
Title: Enhanced CD4 T cell responsiveness in the absence of 4-1BB.
Volume: 174
Issue: 11
Pages: 6803-8
Publication      
First Author: Zhong X
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for asilomar.
Publication
First Author: Martínez Gómez JM
Year: 2013
Journal: PLoS One
Title: CD137 facilitates the resolution of acute DSS-induced colonic inflammation in mice.
Volume: 8
Issue: 9
Pages: e73277
Publication
First Author: Maerten P
Year: 2006
Journal: Clin Exp Immunol
Title: Involvement of 4-1BB (CD137)-4-1BBligand interaction in the modulation of CD4 T cell-mediated inflammatory colitis.
Volume: 143
Issue: 2
Pages: 228-36
Publication
First Author: Nguyen QT
Year: 2009
Journal: Infect Immun
Title: Blockade of CD137 signaling counteracts polymicrobial sepsis induced by cecal ligation and puncture.
Volume: 77
Issue: 9
Pages: 3932-8
Publication
First Author: Sharma RK
Year: 2009
Journal: Cancer Res
Title: Costimulation as a platform for the development of vaccines: a peptide-based vaccine containing a novel form of 4-1BB ligand eradicates established tumors.
Volume: 69
Issue: 10
Pages: 4319-26
Publication
First Author: Kwon BS
Year: 2002
Journal: J Immunol
Title: Immune responses in 4-1BB (CD137)-deficient mice.
Volume: 168
Issue: 11
Pages: 5483-90
Publication
First Author: Miki H
Year: 2020
Journal: J Immunol
Title: 4-1BBL Regulates the Polarization of Macrophages, and Inhibition of 4-1BBL Signaling Alleviates Imiquimod-Induced Psoriasis.
Volume: 204
Issue: 7
Pages: 1892-1903
Publication
First Author: Hsieh EH
Year: 2010
Journal: Am J Pathol
Title: CD137 is required for M cell functional maturation but not lineage commitment.
Volume: 177
Issue: 2
Pages: 666-76
Publication
First Author: Behrendt AK
Year: 2012
Journal: Clin Exp Immunol
Title: CD137 deficiency does not affect development of airway inflammation or respiratory tolerance induction in murine models.
Volume: 168
Issue: 3
Pages: 308-17
Publication
First Author: Humphreys IR
Year: 2010
Journal: Eur J Immunol
Title: Biphasic role of 4-1BB in the regulation of mouse cytomegalovirus-specific CD8(+) T cells.
Volume: 40
Issue: 10
Pages: 2762-8
Publication
First Author: Choi BK
Year: 2009
Journal: J Immunol
Title: 4-1BB functions as a survival factor in dendritic cells.
Volume: 182
Issue: 7
Pages: 4107-15
Publication
First Author: Lee SJ
Year: 2013
Journal: Eur J Immunol
Title: 4-1BB signal stimulates the activation, expansion, and effector functions of γδ T cells in mice and humans.
Volume: 43
Issue: 7
Pages: 1839-48
Publication
First Author: Lee SC
Year: 2005
Journal: Infect Immun
Title: 4-1BB (CD137) is required for rapid clearance of Listeria monocytogenes infection.
Volume: 73
Issue: 8
Pages: 5144-51
Publication
First Author: Tan JT
Year: 2000
Journal: Transplantation
Title: Analysis of expression and function of the costimulatory molecule 4-1BB in alloimmune responses.
Volume: 70
Issue: 1
Pages: 175-83
Publication
First Author: Chalupny NJ
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: T-cell activation molecule 4-1BB binds to extracellular matrix proteins.
Volume: 89
Issue: 21
Pages: 10360-4
Publication
First Author: Schwarz H
Year: 1993
Journal: Gene
Title: A receptor induced by lymphocyte activation (ILA): a new member of the human nerve-growth-factor/tumor-necrosis-factor receptor family.
Volume: 134
Issue: 2
Pages: 295-8
Publication
First Author: Schwarz H
Year: 1995
Journal: Blood
Title: ILA, the human 4-1BB homologue, is inducible in lymphoid and other cell lineages.
Volume: 85
Issue: 4
Pages: 1043-52
Publication
First Author: Pollok KE
Year: 1995
Journal: Eur J Immunol
Title: Regulation of 4-1BB expression by cell-cell interactions and the cytokines, interleukin-2 and interleukin-4.
Volume: 25
Issue: 2
Pages: 488-94
Publication
First Author: Setareh M
Year: 1995
Journal: Gene
Title: A mRNA variant encoding a soluble form of 4-1BB, a member of the murine NGF/TNF receptor family.
Volume: 164
Issue: 2
Pages: 311-5
Publication
First Author: Choi BK
Year: 2004
Journal: J Leukoc Biol
Title: 4-1BB-dependent inhibition of immunosuppression by activated CD4+CD25+ T cells.
Volume: 75
Issue: 5
Pages: 785-91
Publication
First Author: Zheng G
Year: 2004
Journal: J Immunol
Title: The 4-1BB costimulation augments the proliferation of CD4+CD25+ regulatory T cells.
Volume: 173
Issue: 4
Pages: 2428-34
Publication
First Author: Lee SJ
Year: 2004
Journal: J Immunol
Title: 4-1BB and OX40 dual costimulation synergistically stimulate primary specific CD8 T cells for robust effector function.
Volume: 173
Issue: 5
Pages: 3002-12
Publication
First Author: Irie J
Year: 2006
Journal: Immunogenetics
Title: Genetic control of anti-Sm autoantibody production in NOD congenic mice narrowed to the Idd9.3 region.
Volume: 58
Issue: 1
Pages: 9-14
Publication
First Author: McNamara JO
Year: 2008
Journal: J Clin Invest
Title: Multivalent 4-1BB binding aptamers costimulate CD8+ T cells and inhibit tumor growth in mice.
Volume: 118
Issue: 1
Pages: 376-86
Publication
First Author: Robertson SJ
Year: 2008
Journal: J Immunol
Title: CD137 costimulation of CD8+ T cells confers resistance to suppression by virus-induced regulatory T cells.
Volume: 180
Issue: 8
Pages: 5267-74
Publication
First Author: Sun Y
Year: 2006
Journal: J Immunol
Title: Inhibition of Th2-mediated allergic airway inflammatory disease by CD137 costimulation.
Volume: 177
Issue: 2
Pages: 814-21
Publication
First Author: Lee SC
Year: 2009
Journal: Infect Immun
Title: Stimulation of the molecule 4-1BB enhances host defense against Listeria monocytogenes infection in mice by inducing rapid infiltration and activation of neutrophils and monocytes.
Volume: 77
Issue: 5
Pages: 2168-76
Publication
First Author: Lee SW
Year: 2009
Journal: J Immunol
Title: Hypercostimulation through 4-1BB distorts homeostasis of immune cells.
Volume: 182
Issue: 11
Pages: 6753-62
Publication
First Author: Yi L
Year: 2014
Journal: PLoS One
Title: Human and mouse CD137 have predominantly different binding CRDs to their respective ligands.
Volume: 9
Issue: 1
Pages: e86337
Publication
First Author: Mardiana S
Year: 2017
Journal: Cancer Res
Title: A Multifunctional Role for Adjuvant Anti-4-1BB Therapy in Augmenting Antitumor Response by Chimeric Antigen Receptor T Cells.
Volume: 77
Issue: 6
Pages: 1296-1309
Publication      
First Author: Kamata-Sakurai M
Year: 2020
Journal: Cancer Discov
Title: Antibody to CD137 Activated by Extracellular Adenosine Triphosphate Is Tumor Selective and Broadly Effective In Vivo without Systemic Immune Activation.
Publication  
First Author: Yeo YA
Year: 2012
Journal: J Neuroinflammation
Title: CD137 ligand activated microglia induces oligodendrocyte apoptosis via reactive oxygen species.
Volume: 9
Pages: 173
Publication
First Author: Forsberg MH
Year: 2017
Journal: J Immunol
Title: CD137 Plays Both Pathogenic and Protective Roles in Type 1 Diabetes Development in NOD Mice.
Volume: 198
Issue: 10
Pages: 3857-3868
Publication
First Author: Tan JT
Year: 2000
Journal: J Immunol
Title: 4-1BB costimulation is required for protective anti-viral immunity after peptide vaccination.
Volume: 164
Issue: 5
Pages: 2320-5
Publication
First Author: Lin GH
Year: 2009
Journal: J Immunol
Title: Endogenous 4-1BB ligand plays a critical role in protection from influenza-induced disease.
Volume: 182
Issue: 2
Pages: 934-47
Publication
First Author: Nishimoto H
Year: 2005
Journal: Blood
Title: Costimulation of mast cells by 4-1BB, a member of the tumor necrosis factor receptor superfamily, with the high-affinity IgE receptor.
Volume: 106
Issue: 13
Pages: 4241-8
Publication
First Author: Niu L
Year: 2007
Journal: J Immunol
Title: Cytokine-mediated disruption of lymphocyte trafficking, hemopoiesis, and induction of lymphopenia, anemia, and thrombocytopenia in anti-CD137-treated mice.
Volume: 178
Issue: 7
Pages: 4194-213
Publication
First Author: Wu ZQ
Year: 2003
Journal: Infect Immun
Title: 4-1BB (CD137) differentially regulates murine in vivo protein- and polysaccharide-specific immunoglobulin isotype responses to Streptococcus pneumoniae.
Volume: 71
Issue: 1
Pages: 196-204
Publication
First Author: Lee SW
Year: 2008
Journal: Nat Immunol
Title: Identification of regulatory functions for 4-1BB and 4-1BBL in myelopoiesis and the development of dendritic cells.
Volume: 9
Issue: 8
Pages: 917-26
Publication
First Author: Madireddi S
Year: 2014
Journal: J Exp Med
Title: Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies.
Volume: 211
Issue: 7
Pages: 1433-48
Publication
First Author: Vinay DS
Year: 2003
Journal: Immunol Cell Biol
Title: Immunity in the absence of CD28 and CD137 (4-1BB) molecules.
Volume: 81
Issue: 3
Pages: 176-84
Publication
First Author: Sabbagh L
Year: 2008
Journal: J Immunol
Title: ERK-dependent Bim modulation downstream of the 4-1BB-TRAF1 signaling axis is a critical mediator of CD8 T cell survival in vivo.
Volume: 180
Issue: 12
Pages: 8093-101
Publication
First Author: Cole SL
Year: 2014
Journal: J Immunol
Title: Involvement of the 4-1BB/4-1BBL pathway in control of monocyte numbers by invariant NKT cells.
Volume: 192
Issue: 8
Pages: 3898-907
Publication
First Author: Tang Q
Year: 2013
Journal: Eur J Immunol
Title: CD137 ligand signaling enhances myelopoiesis during infections.
Volume: 43
Issue: 6
Pages: 1555-67
Publication
First Author: Kim YH
Year: 2005
Journal: Cell Immunol
Title: 4-1BB costimulation enhances HSV-1-specific CD8+ T cell responses by the induction of CD11c+CD8+ T cells.
Volume: 238
Issue: 2
Pages: 76-86
Publication
First Author: Kim CS
Year: 2011
Journal: Diabetes
Title: Deficiency for costimulatory receptor 4-1BB protects against obesity-induced inflammation and metabolic disorders.
Volume: 60
Issue: 12
Pages: 3159-68
Publication
First Author: Kang SW
Year: 2017
Journal: Cancer Res
Title: Anti-CD137 Suppresses Tumor Growth by Blocking Reverse Signaling by CD137 Ligand.
Volume: 77
Issue: 21
Pages: 5989-6000
Publication
First Author: Shin HH
Year: 2007
Journal: FEBS Lett
Title: Absence of 4-1BB increases cell influx into the peritoneal cavity in response to LPS stimulation by decreasing macrophage IL-10 levels.
Volume: 581
Issue: 22
Pages: 4355-60
Publication
First Author: Vinay DS
Year: 2004
Journal: J Immunol
Title: CD137-deficient mice have reduced NK/NKT cell numbers and function, are resistant to lipopolysaccharide-induced shock syndromes, and have lower IL-4 responses.
Volume: 173
Issue: 6
Pages: 4218-29
Publication
First Author: Jeon HJ
Year: 2010
Journal: Circulation
Title: CD137 (4-1BB) deficiency reduces atherosclerosis in hyperlipidemic mice.
Volume: 121
Issue: 9
Pages: 1124-33
Publication
First Author: Eun SY
Year: 2015
Journal: J Immunol
Title: 4-1BB ligand signaling to T cells limits T cell activation.
Volume: 194
Issue: 1
Pages: 134-41
Publication
First Author: Seo SK
Year: 2003
Journal: J Immunol
Title: Blocking 4-1BB/4-1BB ligand interactions prevents herpetic stromal keratitis.
Volume: 171
Issue: 2
Pages: 576-83
Publication
First Author: Shin HH
Year: 2006
Journal: FEBS Lett
Title: A signal through 4-1BB ligand inhibits receptor for activation of nuclear factor-kappaB ligand (RANKL)-induced osteoclastogenesis by increasing interferon (IFN)-beta production.
Volume: 580
Issue: 6
Pages: 1601-6
Publication
First Author: Kim HJ
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Reverse signaling through the costimulatory ligand CD137L in epithelial cells is essential for natural killer cell-mediated acute tissue inflammation.
Volume: 109
Issue: 1
Pages: E13-22
Publication
First Author: Yang J
Year: 2008
Journal: Eur J Immunol
Title: The 4-1BB ligand and 4-1BB expressed on osteoclast precursors enhance RANKL-induced osteoclastogenesis via bi-directional signaling.
Volume: 38
Issue: 6
Pages: 1598-609
Publication
First Author: Shao Z
Year: 2008
Journal: Mol Immunol
Title: Characterisation of soluble murine CD137 and its association with systemic lupus.
Volume: 45
Issue: 15
Pages: 3990-9
Publication
First Author: Alderson MR
Year: 1994
Journal: Eur J Immunol
Title: Molecular and biological characterization of human 4-1BB and its ligand.
Volume: 24
Issue: 9
Pages: 2219-27
Publication
First Author: Zhou Z
Year: 1995
Journal: Immunol Lett
Title: Characterization of human homologue of 4-1BB and its ligand.
Volume: 45
Issue: 1-2
Pages: 67-73
Publication
First Author: Loo DT
Year: 1997
Journal: J Biol Chem
Title: Analysis of 4-1BBL and laminin binding to murine 4-1BB, a member of the tumor necrosis factor receptor superfamily, and comparison with human 4-1BB.
Volume: 272
Issue: 10
Pages: 6448-56
Publication
First Author: Bertram EM
Year: 2004
Journal: J Immunol
Title: A switch in costimulation from CD28 to 4-1BB during primary versus secondary CD8 T cell response to influenza in vivo.
Volume: 172
Issue: 2
Pages: 981-8
Publication
First Author: Dawicki W
Year: 2004
Journal: J Immunol
Title: 4-1BB and OX40 act independently to facilitate robust CD8 and CD4 recall responses.
Volume: 173
Issue: 10
Pages: 5944-51
Publication
First Author: Nam KO
Year: 2005
Journal: J Immunol
Title: Cross-linking of 4-1BB activates TCR-signaling pathways in CD8+ T lymphocytes.
Volume: 174
Issue: 4
Pages: 1898-905
Publication
First Author: Moens L
Year: 2007
Journal: J Leukoc Biol
Title: Distinct approaches to investigate the importance of the murine 4-1BB 4-1BBL interaction in the antibody response to Streptococcus pneumoniae.
Volume: 82
Issue: 3
Pages: 638-44
Publication
First Author: Kim J
Year: 2003
Journal: Exp Mol Med
Title: Constitutive expression of 4-1BB on T cells enhances CD4+ T cell responses.
Volume: 35
Issue: 6
Pages: 509-17
Publication
First Author: Jiang D
Year: 2008
Journal: J Immunol
Title: CD137 induces proliferation of murine hematopoietic progenitor cells and differentiation to macrophages.
Volume: 181
Issue: 6
Pages: 3923-32
Publication
First Author: Tang Q
Year: 2011
Journal: PLoS One
Title: Species difference of CD137 ligand signaling in human and murine monocytes.
Volume: 6
Issue: 1
Pages: e16129
Publication
First Author: Martínez Gómez JM
Year: 2012
Journal: J Neurosci
Title: Development of experimental autoimmune encephalomyelitis critically depends on CD137 ligand signaling.
Volume: 32
Issue: 50
Pages: 18246-52
Publication  
First Author: Choi BK
Year: 2020
Journal: Front Immunol
Title: The Murine CD137/CD137 Ligand Signalosome: A Signal Platform Generating Signal Complexity.
Volume: 11
Pages: 553715
Publication  
First Author: Le NH
Year: 2013
Journal: Mediators Inflamm
Title: Blockade of 4-1BB and 4-1BBL interaction reduces obesity-induced skeletal muscle inflammation.
Volume: 2013
Pages: 865159
Publication
First Author: Barsoumian HB
Year: 2016
Journal: PLoS One
Title: 4-1BB Signaling in Conventional T Cells Drives IL-2 Production That Overcomes CD4+CD25+FoxP3+ T Regulatory Cell Suppression.
Volume: 11
Issue: 4
Pages: e0153088
Publication
First Author: Sabbagh L
Year: 2013
Journal: J Leukoc Biol
Title: Leukocyte-specific protein 1 links TNF receptor-associated factor 1 to survival signaling downstream of 4-1BB in T cells.
Volume: 93
Issue: 5
Pages: 713-21
Publication
First Author: Pulle G
Year: 2006
Journal: J Immunol
Title: IL-15-dependent induction of 4-1BB promotes antigen-independent CD8 memory T cell survival.
Volume: 176
Issue: 5
Pages: 2739-48
Publication
First Author: Sharma RK
Year: 2010
Journal: Cancer Res
Title: 4-1BB ligand as an effective multifunctional immunomodulator and antigen delivery vehicle for the development of therapeutic cancer vaccines.
Volume: 70
Issue: 10
Pages: 3945-54
Publication
First Author: Li Q
Year: 2007
Journal: Int J Biol Sci
Title: Adjuvant effect of anti-4-1BB mAb administration in adoptive T cell therapy of cancer.
Volume: 3
Issue: 7
Pages: 455-62
Publication
First Author: Nguyen QT
Year: 2013
Journal: Infect Immun
Title: CD137 expressed on neutrophils plays dual roles in antibacterial responses against Gram-positive and Gram-negative bacterial infections.
Volume: 81
Issue: 6
Pages: 2168-77
Publication
First Author: Giardino Torchia ML
Year: 2015
Journal: Eur J Immunol
Title: c-IAP ubiquitin protein ligase activity is required for 4-1BB signaling and CD8(+) memory T-cell survival.
Volume: 45
Issue: 9
Pages: 2672-82
Publication
First Author: Montufar-Solis D
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Involvement of Ly6C, 4-1BB, and KLRG1 in the activation of lamina propria lymphocytes in the small intestine of sanroque mice.
Volume: 483
Issue: 1
Pages: 590-595
Publication
First Author: Lee SJ
Year: 2007
Journal: J Immunol
Title: CD134 Costimulation Couples the CD137 Pathway to Induce Production of Supereffector CD8 T Cells That Become IL-7 Dependent.
Volume: 179
Issue: 4
Pages: 2203-14
Publication
First Author: Vinay DS
Year: 2007
Journal: Invest Ophthalmol Vis Sci
Title: Absence of 4 1BB gene function exacerbates lacrimal gland inflammation in autoimmune-prone MRL-Faslpr mice.
Volume: 48
Issue: 10
Pages: 4608-15
Publication
First Author: Vinay DS
Year: 2007
Journal: Immunology
Title: Role of endogenous 4-1BB in the development of systemic lupus erythematosus.
Volume: 122
Issue: 3
Pages: 394-400
Publication
First Author: Fukushima A
Year: 2005
Journal: J Immunol
Title: Engagement of 4-1BB inhibits the development of experimental allergic conjunctivitis in mice.
Volume: 175
Issue: 8
Pages: 4897-903
Publication
First Author: Srivastava RK
Year: 2020
Journal: J Biol Chem
Title: CD137 negatively affects "browning" of white adipose tissue during cold exposure.
Volume: 295
Issue: 7
Pages: 2034-2042
Publication
First Author: Shin HH
Year: 2006
Journal: J Bone Miner Res
Title: Enhanced osteoclastogenesis in 4-1BB-deficient mice caused by reduced interleukin-10.
Volume: 21
Issue: 12
Pages: 1907-12
Publication
First Author: Jung IH
Year: 2014
Journal: FASEB J
Title: CD137-inducing factors from T cells and macrophages accelerate the destabilization of atherosclerotic plaques in hyperlipidemic mice.
Volume: 28
Issue: 11
Pages: 4779-91
Publication
First Author: Bitra A
Year: 2018
Journal: J Biol Chem
Title: Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling.
Volume: 293
Issue: 4
Pages: 1317-1329
Publication
First Author: Ye H
Year: 1999
Journal: Mol Cell
Title: The structural basis for the recognition of diverse receptor sequences by TRAF2.
Volume: 4
Issue: 3
Pages: 321-30
Publication
First Author: Martinez-Forero I
Year: 2013
Journal: J Immunol
Title: T cell costimulation with anti-CD137 monoclonal antibodies is mediated by K63-polyubiquitin-dependent signals from endosomes.
Volume: 190
Issue: 12
Pages: 6694-706
Publication
First Author: Jin J
Year: 2020
Journal: Cell Rep
Title: CD137 Signaling Regulates Acute Colitis via RALDH2-Expressing CD11b-CD103+ DCs.
Volume: 30
Issue: 12
Pages: 4124-4136.e5