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Search results 101 to 200 out of 479 for Ptk2

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Category: Publication
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Type Details Score
Publication
22056317 | J:183673
First Author: Clemente CF
Year: 2012
Journal: J Mol Cell Cardiol
Title: Focal adhesion kinase governs cardiac concentric hypertrophic growth by activating the AKT and mTOR pathways.
Volume: 52
Issue: 2
Pages: 493-501
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Publication
12051751 | J:76618
First Author: Takeuchi T
Year: 2002
Journal: Biochem Biophys Res Commun
Title: Flp recombinase transgenic mice of C57BL/6 strain for conditional gene targeting.
Volume: 293
Issue: 3
Pages: 953-7
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Publication
17417603 | J:121630
 
First Author: Kokkinos MI
Year: 2007
Journal: Mol Vis
Title: Focal adhesion kinase (FAK) expression and activation during lens development.
Volume: 13
Pages: 418-30
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Publication
18297732 | J:231279
First Author: Cram EJ
Year: 2008
Journal: Dev Dyn
Title: Functional characterization of KIN-32, the Caenorhabditis elegans homolog of focal adhesion kinase.
Volume: 237
Issue: 3
Pages: 837-46
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Publication
2132399 | J:638
First Author: Russell JC
Year: 1990
Journal: Diabetes Res
Title: Effects of advancing age and severe food restriction on pathological processes in the insulin resistant JCR:LA-corpulent rat.
Volume: 15
Issue: 2
Pages: 53-62
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Publication
1458538 | J:16361
First Author: Zachary I
Year: 1992
Journal: Cell
Title: Focal adhesion kinase (p125FAK): a point of convergence in the action of neuropeptides, integrins, and oncogenes.
Volume: 71
Issue: 6
Pages: 891-4
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Publication
7685911 | J:12761
First Author: Choi K
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: Expression of a gene encoding a unique protein-tyrosine kinase within specific fetal- and adult-derived hematopoietic lineages.
Volume: 90
Issue: 12
Pages: 5747-51
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Publication
7487975 | J:29247
First Author: Kanazawa S
Year: 1995
Journal: Biochem Biophys Res Commun
Title: Integrin stimulation decreases tyrosine phosphorylation and activity of focal adhesion kinase in thymocytes.
Volume: 215
Issue: 2
Pages: 438-45
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Publication
8843417 | J:34576
First Author: Tremblay L
Year: 1996
Journal: Mol Endocrinol
Title: Regulation and activation of focal adhesion kinase and paxillin during the adhesion, proliferation, and differentiation of prostatic epithelial cells in vitro and in vivo.
Volume: 10
Issue: 8
Pages: 1010-20
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Publication
9067592 | J:38845
 
First Author: Ilić D
Year: 1997
Journal: J Cell Sci
Title: Focal adhesion kinase: at the crossroads of signal transduction.
Volume: 110 ( Pt 4)
Pages: 401-7
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Publication
9361011 | J:44050
First Author: Takeuchi Y
Year: 1997
Journal: J Biol Chem
Title: Differentiation and transforming growth factor-beta receptor down-regulation by collagen-alpha2beta1 integrin interaction is mediated by focal adhesion kinase and its downstream signals in murine osteoblastic cells.
Volume: 272
Issue: 46
Pages: 29309-16
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Publication
10413676 | J:57324
 
First Author: Sieg DJ
Year: 1999
Journal: J Cell Sci
Title: Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration.
Volume: 112 ( Pt 16)
Pages: 2677-91
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Publication
12379477 | J:79768
First Author: Katz BZ
Year: 2002
Journal: Biochim Biophys Acta
Title: Direct transmembrane clustering and cytoplasmic dimerization of focal adhesion kinase initiates its tyrosine phosphorylation.
Volume: 1592
Issue: 2
Pages: 141-52
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Publication
12615911 | J:82176
First Author: Hsia DA
Year: 2003
Journal: J Cell Biol
Title: Differential regulation of cell motility and invasion by FAK.
Volume: 160
Issue: 5
Pages: 753-67
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Publication
16159962 | J:101750
First Author: Hamadi A
Year: 2005
Journal: J Cell Sci
Title: Regulation of focal adhesion dynamics and disassembly by phosphorylation of FAK at tyrosine 397.
Volume: 118
Issue: Pt 19
Pages: 4415-25
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Publication
16847103 | J:111244
First Author: Pirone DM
Year: 2006
Journal: J Cell Biol
Title: An inhibitory role for FAK in regulating proliferation: a link between limited adhesion and RhoA-ROCK signaling.
Volume: 174
Issue: 2
Pages: 277-88
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Publication
16780927 | J:112406
First Author: Arnesen SM
Year: 2006
Journal: Mech Ageing Dev
Title: Age-related changes in focal adhesions lead to altered cell behavior in tendon fibroblasts.
Volume: 127
Issue: 9
Pages: 726-32
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Publication
16889663 | J:113411
 
First Author: Corsi JM
Year: 2006
Journal: BMC Genomics
Title: Organization and post-transcriptional processing of focal adhesion kinase gene.
Volume: 7
Pages: 198
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Publication
10967115 | J:115350
First Author: Lebrun P
Year: 2000
Journal: J Biol Chem
Title: Cell adhesion and focal adhesion kinase regulate insulin receptor substrate-1 expression.
Volume: 275
Issue: 49
Pages: 38371-7
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Publication
17303567 | J:121130
First Author: Lim Y
Year: 2007
Journal: J Biol Chem
Title: Focal adhesion kinase is negatively regulated by phosphorylation at tyrosine 407.
Volume: 282
Issue: 14
Pages: 10398-404
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Publication
15537495 | J:132549
First Author: Peng X
Year: 2004
Journal: Cardiovasc Res
Title: Overexpression of focal adhesion kinase in vascular endothelial cells promotes angiogenesis in transgenic mice.
Volume: 64
Issue: 3
Pages: 421-30
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Publication
17986008 | J:135360
First Author: Hoshina N
Year: 2007
Journal: Genes Cells
Title: Focal adhesion kinase regulates laminin-induced oligodendroglial process outgrowth.
Volume: 12
Issue: 11
Pages: 1245-54
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Publication
18303050 | J:138479
First Author: Iwanicki MP
Year: 2008
Journal: J Cell Sci
Title: FAK, PDZ-RhoGEF and ROCKII cooperate to regulate adhesion movement and trailing-edge retraction in fibroblasts.
Volume: 121
Issue: Pt 6
Pages: 895-905
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Publication
18606490 | J:139871
First Author: Kaneda T
Year: 2008
Journal: Cancer Lett
Title: Mutation of Y925F in focal adhesion kinase (FAK) suppresses melanoma cell proliferation and metastasis.
Volume: 270
Issue: 2
Pages: 354-61
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Publication
19364917 | J:148985
First Author: Chan KT
Year: 2009
Journal: J Cell Biol
Title: FAK alters invadopodia and focal adhesion composition and dynamics to regulate breast cancer invasion.
Volume: 185
Issue: 2
Pages: 357-70
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Publication
18787183 | J:159798
First Author: Sayers RL
Year: 2008
Journal: Arterioscler Thromb Vasc Biol
Title: FRNK expression promotes smooth muscle cell maturation during vascular development and after vascular injury.
Volume: 28
Issue: 12
Pages: 2115-22
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Publication
20682312 | J:164403
First Author: Ma Y
Year: 2010
Journal: FEBS Lett
Title: Oxazolone-induced over-expression of focal adhesion kinase in colonic epithelial cells of colitis mouse model.
Volume: 584
Issue: 18
Pages: 3949-54
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Publication
21555563 | J:171897
First Author: Swanson PA 2nd
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Enteric commensal bacteria potentiate epithelial restitution via reactive oxygen species-mediated inactivation of focal adhesion kinase phosphatases.
Volume: 108
Issue: 21
Pages: 8803-8
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Publication
21471441 | J:173101
First Author: Han B
Year: 2011
Journal: J Immunol
Title: TGF-beta i promotes islet beta-cell function and regeneration.
Volume: 186
Issue: 10
Pages: 5833-44
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Publication
21969470 | J:177720
First Author: Pan YR
Year: 2011
Journal: J Cell Biol
Title: FAK is required for the assembly of podosome rosettes.
Volume: 195
Issue: 1
Pages: 113-29
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Publication
22270917 | J:180652
First Author: Lawson C
Year: 2012
Journal: J Cell Biol
Title: FAK promotes recruitment of talin to nascent adhesions to control cell motility.
Volume: 196
Issue: 2
Pages: 223-32
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Publication
22366060 | J:185063
First Author: Gupta A
Year: 2012
Journal: Biochim Biophys Acta
Title: Focal adhesion kinase negatively regulates neuronal insulin resistance.
Volume: 1822
Issue: 6
Pages: 1030-7
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Publication
24043700 | J:201823
First Author: Choi CH
Year: 2013
Journal: J Cell Biol
Title: pH sensing by FAK-His58 regulates focal adhesion remodeling.
Volume: 202
Issue: 6
Pages: 849-59
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Publication
24347609 | J:211482
First Author: Gregor M
Year: 2014
Journal: FASEB J
Title: Mechanosensing through focal adhesion-anchored intermediate filaments.
Volume: 28
Issue: 2
Pages: 715-29
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Publication
27033120 | J:250879
First Author: Masdeu Mdel M
Year: 2016
Journal: Biochim Biophys Acta
Title: New partners and phosphorylation sites of focal adhesion kinase identified by mass spectrometry.
Volume: 1860
Issue: 7
Pages: 1388-94
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Publication
29597831 | J:264727
First Author: Ying L
Year: 2018
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Developmental differences in focal adhesion kinase expression modulate pulmonary endothelial barrier function in response to inflammation.
Volume: 315
Issue: 1
Pages: L66-L77
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Publication
24809783 | J:320205
First Author: van Miltenburg MH
Year: 2014
Journal: Br J Cancer
Title: Mammary gland-specific ablation of focal adhesion kinase reduces the incidence of p53-mediated mammary tumour formation.
Volume: 110
Issue: 11
Pages: 2747-55
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Publication
34914633 | J:321195
 
First Author: Ray A
Year: 2022
Journal: JCI Insight
Title: Stromal architecture directs early dissemination in pancreatic ductal adenocarcinoma.
Volume: 7
Issue: 3
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Publication
19028502 | J:149181
First Author: Hakim ZS
Year: 2009
Journal: J Mol Cell Cardiol
Title: FAK regulates cardiomyocyte survival following ischemia/reperfusion.
Volume: 46
Issue: 2
Pages: 241-8
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Publication
21084629 | J:168496
First Author: Abshire MY
Year: 2011
Journal: J Leukoc Biol
Title: Macrophage motility requires distinct α5β1/FAK and α4β1/paxillin signaling events.
Volume: 89
Issue: 2
Pages: 251-7
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Publication
17525272 | J:122160
First Author: Ilic D
Year: 2007
Journal: Am J Pathol
Title: Focal adhesion kinase controls pH-dependent epidermal barrier homeostasis by regulating actin-directed Na+/H+ exchanger 1 plasma membrane localization.
Volume: 170
Issue: 6
Pages: 2055-67
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Publication
25274820 | J:216596
First Author: Grove M
Year: 2014
Journal: J Neurosci
Title: FAK is required for Schwann cell spreading on immature basal lamina to coordinate the radial sorting of peripheral axons with myelination.
Volume: 34
Issue: 40
Pages: 13422-34
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Publication
27106291 | J:235162
First Author: Wheaton AK
Year: 2016
Journal: Am J Physiol Lung Cell Mol Physiol
Title: The vitronectin RGD motif regulates TGF-β-induced alveolar epithelial cell apoptosis.
Volume: 310
Issue: 11
Pages: L1206-17
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Publication
23264658 | J:192606
First Author: Park SY
Year: 2013
Journal: J Immunol
Title: Focal adhesion kinase regulates the localization and retention of pro-B cells in bone marrow microenvironments.
Volume: 190
Issue: 3
Pages: 1094-102
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Publication
22941736 | J:190159
First Author: Ray BJ
Year: 2012
Journal: J Leukoc Biol
Title: Regulation of osteoclast structure and function by FAK family kinases.
Volume: 92
Issue: 5
Pages: 1021-8
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Publication
15967814 | J:99637
First Author: Shen TL
Year: 2005
Journal: J Cell Biol
Title: Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis.
Volume: 169
Issue: 6
Pages: 941-52
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Publication
24901456 | J:246920
First Author: Owen KA
Year: 2014
Journal: PLoS Pathog
Title: Activation of focal adhesion kinase by Salmonella suppresses autophagy via an Akt/mTOR signaling pathway and promotes bacterial survival in macrophages.
Volume: 10
Issue: 6
Pages: e1004159
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Publication
20708588 | J:163669
First Author: Ashton GH
Year: 2010
Journal: Dev Cell
Title: Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling.
Volume: 19
Issue: 2
Pages: 259-69
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Publication
22734001 | J:185347
First Author: Lim ST
Year: 2012
Journal: J Cell Biol
Title: Nuclear-localized focal adhesion kinase regulates inflammatory VCAM-1 expression.
Volume: 197
Issue: 7
Pages: 907-19
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Publication
27994061 | J:240718
First Author: Cheng Z
Year: 2017
Journal: J Biol Chem
Title: Focal Adhesion Kinase-mediated Phosphorylation of Beclin1 Protein Suppresses Cardiomyocyte Autophagy and Initiates Hypertrophic Growth.
Volume: 292
Issue: 6
Pages: 2065-2079
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Publication
19776009 | J:157804
First Author: Corsi JM
Year: 2009
Journal: J Biol Chem
Title: Autophosphorylation-independent and -dependent functions of focal adhesion kinase during development.
Volume: 284
Issue: 50
Pages: 34769-76
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Publication
14642275 | J:86453
First Author: Beggs HE
Year: 2003
Journal: Neuron
Title: FAK deficiency in cells contributing to the basal lamina results in cortical abnormalities resembling congenital muscular dystrophies.
Volume: 40
Issue: 3
Pages: 501-14
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Publication
28165007 | J:243820
 
First Author: Luk CT
Year: 2017
Journal: Nat Commun
Title: FAK signalling controls insulin sensitivity through regulation of adipocyte survival.
Volume: 8
Pages: 14360
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Publication
20150423 | J:162274
First Author: Chan KT
Year: 2010
Journal: J Biol Chem
Title: Regulation of adhesion dynamics by calpain-mediated proteolysis of focal adhesion kinase (FAK).
Volume: 285
Issue: 15
Pages: 11418-26
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Publication
31014956 | J:287640
First Author: Yoshioka T
Year: 2019
Journal: Am J Pathol
Title: CD147/Basigin Deficiency Prevents the Development of Podocyte Injury through FAK Signaling.
Volume: 189
Issue: 7
Pages: 1338-1350
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Publication
17438336 | J:123001
First Author: Schlaepfer DD
Year: 2007
Journal: J Biol Chem
Title: Tumor necrosis factor-alpha stimulates focal adhesion kinase activity required for mitogen-activated kinase-associated interleukin 6 expression.
Volume: 282
Issue: 24
Pages: 17450-9
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Publication
23726908 | J:203219
First Author: Lange J
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Influence of focal adhesion kinase on the mechanical behavior of cell populations.
Volume: 436
Issue: 2
Pages: 246-51
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Publication
10931187 | J:230390
First Author: Della Morte R
Year: 2000
Journal: Eur J Biochem
Title: Echistatin inhibits pp125FAK autophosphorylation, paxillin phosphorylation and pp125FAK-paxillin interaction in fibronectin-adherent melanoma cells.
Volume: 267
Issue: 16
Pages: 5047-54
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Publication
36870331 | J:334889
First Author: Shiraishi K
Year: 2023
Journal: Cell
Title: Biophysical forces mediated by respiration maintain lung alveolar epithelial cell fate.
Volume: 186
Issue: 7
Pages: 1478-1492.e15
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Publication
36012331 | J:327939
 
First Author: Saleh B
Year: 2022
Journal: Int J Mol Sci
Title: FAK-Mediated Signaling Controls Amyloid Beta Overload, Learning and Memory Deficits in a Mouse Model of Alzheimer's Disease.
Volume: 23
Issue: 16
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Publication
15138291 | J:273522
First Author: Subauste MC
Year: 2004
Journal: J Cell Biol
Title: Vinculin modulation of paxillin-FAK interactions regulates ERK to control survival and motility.
Volume: 165
Issue: 3
Pages: 371-81
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19168634 | J:146139
First Author: Digman MA
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Stoichiometry of molecular complexes at adhesions in living cells.
Volume: 106
Issue: 7
Pages: 2170-5
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17526730 | J:123620
First Author: Hakim ZS
Year: 2007
Journal: Mol Cell Biol
Title: Conditional deletion of focal adhesion kinase leads to defects in ventricular septation and outflow tract alignment.
Volume: 27
Issue: 15
Pages: 5352-64
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Publication
16585062 | J:111499
First Author: Greenberg RS
Year: 2006
Journal: FASEB J
Title: FAK-dependent regulation of myofibroblast differentiation.
Volume: 20
Issue: 7
Pages: 1006-8
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Publication
22971575 | J:193298
First Author: Ridgway RA
Year: 2012
Journal: Carcinogenesis
Title: Focal adhesion kinase is required for β-catenin-induced mobilization of epidermal stem cells.
Volume: 33
Issue: 12
Pages: 2369-76
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Publication
23263281 | J:195230
First Author: Akhtar N
Year: 2013
Journal: Nat Cell Biol
Title: An integrin-ILK-microtubule network orients cell polarity and lumen formation in glandular epithelium.
Volume: 15
Issue: 1
Pages: 17-27
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Publication
36017799 | J:329047
 
First Author: Rodriguez UA
Year: 2022
Journal: Development
Title: Focal adhesion kinase-mediated signaling controls the onset of pancreatic cell differentiation.
Volume: 149
Issue: 17
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Publication
21757658 | J:191848
First Author: Cheng Z
Year: 2011
Journal: Arterioscler Thromb Vasc Biol
Title: Focal adhesion kinase regulates smooth muscle cell recruitment to the developing vasculature.
Volume: 31
Issue: 10
Pages: 2193-202
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Publication
25456130 | J:218754
First Author: Chatterjee A
Year: 2014
Journal: Cell Rep
Title: Regulation of Stat5 by FAK and PAK1 in Oncogenic FLT3- and KIT-Driven Leukemogenesis.
Volume: 9
Issue: 4
Pages: 1333-48
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Publication
16391003 | J:104401
First Author: Braren R
Year: 2006
Journal: J Cell Biol
Title: Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation.
Volume: 172
Issue: 1
Pages: 151-62
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Publication
19454481 | J:150568
First Author: Schlomann U
Year: 2009
Journal: J Cell Sci
Title: The stimulation of dendrite growth by Sema3A requires integrin engagement and focal adhesion kinase.
Volume: 122
Issue: Pt 12
Pages: 2034-42
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Publication
20442405 | J:165360
First Author: Lim ST
Year: 2010
Journal: J Biol Chem
Title: Knock-in mutation reveals an essential role for focal adhesion kinase activity in blood vessel morphogenesis and cell motility-polarity but not cell proliferation.
Volume: 285
Issue: 28
Pages: 21526-36
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28154132 | J:318448
First Author: Fu C
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Neuronal migration is mediated by inositol hexakisphosphate kinase 1 via α-actinin and focal adhesion kinase.
Volume: 114
Issue: 8
Pages: 2036-2041
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Publication
17093062 | J:121008
First Author: Chang F
Year: 2007
Journal: Mol Biol Cell
Title: FAK potentiates Rac1 activation and localization to matrix adhesion sites: a role for betaPIX.
Volume: 18
Issue: 1
Pages: 253-64
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Publication
12941275 | J:85235
First Author: Xie Z
Year: 2003
Journal: Cell
Title: Serine 732 phosphorylation of FAK by Cdk5 is important for microtubule organization, nuclear movement, and neuronal migration.
Volume: 114
Issue: 4
Pages: 469-82
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Publication
24089517 | J:204989
First Author: Malenczyk K
Year: 2013
Journal: J Biol Chem
Title: CB1 cannabinoid receptors couple to focal adhesion kinase to control insulin release.
Volume: 288
Issue: 45
Pages: 32685-99
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19553453 | J:231277
First Author: Shi Y
Year: 2009
Journal: J Neurosci
Title: Focal adhesion kinase acts downstream of EphB receptors to maintain mature dendritic spines by regulating cofilin activity.
Volume: 29
Issue: 25
Pages: 8129-42
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Publication
19545541 | J:151496
First Author: Andersson S
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Focal adhesion kinase (FAK) activates and stabilizes IGF-1 receptor.
Volume: 387
Issue: 1
Pages: 36-41
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Publication
10366455 | J:55634
First Author: Wang Y
Year: 1999
Journal: Genomics
Title: Mapping the mouse otoconin-90 (Oc90) gene to chromosome 15.
Volume: 58
Issue: 2
Pages: 214-5
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19661918 | J:152901
First Author: Luo SW
Year: 2009
Journal: EMBO J
Title: Regulation of heterochromatin remodelling and myogenin expression during muscle differentiation by FAK interaction with MBD2.
Volume: 28
Issue: 17
Pages: 2568-82
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Publication
19596799 | J:153288
First Author: Chan MW
Year: 2009
Journal: J Cell Sci
Title: FAK, PIP5KIgamma and gelsolin cooperatively mediate force-induced expression of alpha-smooth muscle actin.
Volume: 122
Issue: Pt 15
Pages: 2769-81
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Publication
26139604 | J:225503
First Author: Keeler AB
Year: 2015
Journal: J Biol Chem
Title: Protein Kinase C Phosphorylation of a γ-Protocadherin C-terminal Lipid Binding Domain Regulates Focal Adhesion Kinase Inhibition and Dendrite Arborization.
Volume: 290
Issue: 34
Pages: 20674-86
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Publication
16000375 | J:104069
First Author: Brown MC
Year: 2005
Journal: Mol Biol Cell
Title: Src and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness.
Volume: 16
Issue: 9
Pages: 4316-28
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Publication
15340073 | J:92969
First Author: Westhoff MA
Year: 2004
Journal: Mol Cell Biol
Title: SRC-mediated phosphorylation of focal adhesion kinase couples actin and adhesion dynamics to survival signaling.
Volume: 24
Issue: 18
Pages: 8113-33
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Publication
15494312 | J:94553
First Author: Ishibe S
Year: 2004
Journal: Mol Cell
Title: Paxillin serves as an ERK-regulated scaffold for coordinating FAK and Rac activation in epithelial morphogenesis.
Volume: 16
Issue: 2
Pages: 257-67
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Publication
15309026 | J:95095
First Author: Velling T
Year: 2004
Journal: EMBO Rep
Title: beta1-Integrins induce phosphorylation of Akt on serine 473 independently of focal adhesion kinase and Src family kinases.
Volume: 5
Issue: 9
Pages: 901-5
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Publication
23702483 | J:203223
First Author: Lee JS
Year: 2013
Journal: Biochem Biophys Res Commun
Title: The role of focal adhesion kinase in BMP4 induction of mesenchymal stem cell adipogenesis.
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First Author: Shang N
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First Author: Pasapera AM
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Title: Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation.
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Pages: 877-90
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19126403 | J:145153
First Author: Klemm AH
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Journal: Biochem Biophys Res Commun
Title: Comparing the mechanical influence of vinculin, focal adhesion kinase and p53 in mouse embryonic fibroblasts.
Volume: 379
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Journal: Mol Cell
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First Author: Chauhan BK
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Title: Cdc42- and IRSp53-dependent contractile filopodia tether presumptive lens and retina to coordinate epithelial invagination.
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First Author: Brudvig JJ
Year: 2018
Journal: Mol Neurobiol
Title: MARCKS Is Necessary for Netrin-DCC Signaling and Corpus Callosum Formation.
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First Author: Zhai J
Year: 2003
Journal: J Biol Chem
Title: Direct interaction of focal adhesion kinase with p190RhoGEF.
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Title: A role for CAP, a novel, multifunctional Src homology 3 domain-containing protein in formation of actin stress fibers and focal adhesions.
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Year: 2012
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Title: Rgnef (p190RhoGEF) knockout inhibits RhoA activity, focal adhesion establishment, and cell motility downstream of integrins.
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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