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Search results 401 to 428 out of 428 for Cyfip2

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Type Details Score
Strain
MGI:5003950 | STOCK Tg(Cyfip2-EGFP)IN64Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Protein
P28660
Organism: Mus musculus/domesticus
Length: 1128  
Fragment?: false
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Protein
Q8K1X4
Organism: Mus musculus/domesticus
Length: 1134  
Fragment?: false
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Protein
Q3UDY0
Organism: Mus musculus/domesticus
Length: 614  
Fragment?: true
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Protein
A2AS98
Organism: Mus musculus/domesticus
Length: 1134  
Fragment?: false
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Protein
Q8BVQ3
Organism: Mus musculus/domesticus
Length: 323  
Fragment?: false
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Protein
A1L0U6
Organism: Mus musculus/domesticus
Length: 1133  
Fragment?: true
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Protein
A0A2R8VHC4
Organism: Mus musculus/domesticus
Length: 298  
Fragment?: false
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Publication
10673335 | J:60729
First Author: Suzuki T
Year: 2000
Journal: Genomics
Title: Molecular cloning of a novel apoptosis-related gene, human Nap1 (NCKAP1), and its possible relation to Alzheimer disease.
Volume: 63
Issue: 2
Pages: 246-54
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Publication
24439376 | J:206834
First Author: Chen B
Year: 2014
Journal: Cell
Title: The WAVE regulatory complex links diverse receptors to the actin cytoskeleton.
Volume: 156
Issue: 1-2
Pages: 195-207
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Protein Domain
IPR019137 | Nck-associated_protein-1
Type: Family
Description: Nck-associated protein 1 is part of lamellipodial complex that controls Rac-dependent actin remodeling [, ]. It associates preferentially with the first SH3 domain of Nck and is a component of the WAVE2 complex composed of ABI1, CYFIP1/SRA1, NCKAP1/NAP1 and WASF2/WAVE2. It is also a component of the WAVE1 complex composed of ABI2, CYFIP2, C3orf10/HSPC300, NCKAP1 and WASF1/WAVE1. CYFIP2 binds to activated RAC1 which causes the complex to dissociate, releasing activated WASF1. The complex can also be activated by NCK1. Expression of this protein was found to be markedly reduced in patients with Alzheimer's disease [].
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Publication
30784587 | J:272257
First Author: Davenport EC
Year: 2019
Journal: Cell Rep
Title: Autism and Schizophrenia-Associated CYFIP1 Regulates the Balance of Synaptic Excitation and Inhibition.
Volume: 26
Issue: 8
Pages: 2037-2051.e6
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Publication
18805096 | J:156046
First Author: Napoli I
Year: 2008
Journal: Cell
Title: The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP.
Volume: 134
Issue: 6
Pages: 1042-54
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Protein
F6QD74
Organism: Mus musculus/domesticus
Length: 948  
Fragment?: true
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Protein
G3UZI5
Organism: Mus musculus/domesticus
Length: 229  
Fragment?: true
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Publication
26824476 | -
First Author: Nebel RA
Year: 2016
Journal: PLoS One
Title: Reduced CYFIP1 in Human Neural Progenitors Results in Dysregulation of Schizophrenia and Epilepsy Gene Networks.
Volume: 11
Issue: 1
Pages: e0148039
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Publication
15269173 | -
First Author: Bogdan S
Year: 2004
Journal: Development
Title: Sra-1 interacts with Kette and Wasp and is required for neuronal and bristle development in Drosophila.
Volume: 131
Issue: 16
Pages: 3981-9
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Publication
15294869 | -
First Author: Basu D
Year: 2004
Journal: Development
Title: Interchangeable functions of Arabidopsis PIROGI and the human WAVE complex subunit SRA1 during leaf epidermal development.
Volume: 131
Issue: 17
Pages: 4345-55
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Protein Domain
IPR008081 | Cytoplasmic_FMR1-int
Type: Family
Description: This entry includes cytoplasmic fragile X messenger ribonucleoprotein 1-interacting proteins from humans and their homologues, such as Sra-1 (specifically Rac1-associated protein 1) from Drosophila and PIROGI from Arabidopsis. In humans, there are two members, CYFIP1 and CYFIP2. They both interact with FMRP (Fragile X messenger ribonucleoprotein 1), which is responsible for pathologic manifestations in the Fragile X Syndrome. CYFIP1 interacts with the small GTPase Rac1 [, ]. CYFIP1 represses cap-dependent translation of mRNA by interacting with the initiation factor eIF4E []. CYFIP1 and CYFIP2 are part of the Wiskott-Aldrich syndrome protein-family verprolin-homologous protein (WAVE) complex that regulates actin polymerization at synapses []. Drosophila Sra-1 interacts with the Kette and Wasp. It is required for neuronal and bristle development in Drosophila []. PIROGI is part of a WAVE complex that activates the ARP2/3 complex and is Involved in regulation of actin organization [].
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Publication
26581503 | J:232776
First Author: Dickson PE
Year: 2016
Journal: Psychopharmacology (Berl)
Title: Systems genetics of intravenous cocaine self-administration in the BXD recombinant inbred mouse panel.
Volume: 233
Issue: 4
Pages: 701-14
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Publication
23275536 | J:200219
First Author: Tariq A
Year: 2013
Journal: Nucleic Acids Res
Title: RNA-interacting proteins act as site-specific repressors of ADAR2-mediated RNA editing and fluctuate upon neuronal stimulation.
Volume: 41
Issue: 4
Pages: 2581-93
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Protein
Q7TMB8
Organism: Mus musculus/domesticus
Length: 1253  
Fragment?: false
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Protein
Q5SQX6
Organism: Mus musculus/domesticus
Length: 1253  
Fragment?: false
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Protein
Q8C8R2
Organism: Mus musculus/domesticus
Length: 451  
Fragment?: false
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Protein
A0A0R4J119
Organism: Mus musculus/domesticus
Length: 1251  
Fragment?: false
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Protein
A0A0U1RQ05
Organism: Mus musculus/domesticus
Length: 969  
Fragment?: true
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Publication
- | J:100256
     
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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