Type |
Details |
Score |
Publication |
First Author: |
Tanaka K |
Year: |
1997 |
Journal: |
Exp Cell Res |
Title: |
The in vivo expression pattern of mouse Nek2, a NIMA-related kinase, indicates a role in both mitosis and meiosis. |
Volume: |
237 |
Issue: |
2 |
Pages: |
264-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Janaswami PM |
Year: |
1997 |
Journal: |
Genomics |
Title: |
Identification and genetic mapping of a new polycystic kidney disease on mouse chromosome 8. |
Volume: |
40 |
Issue: |
1 |
Pages: |
101-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim EH |
Year: |
2005 |
Journal: |
Mamm Genome |
Title: |
Quantitative trait loci for proteinuria in the focal glomerulosclerosis mouse model. |
Volume: |
16 |
Issue: |
4 |
Pages: |
242-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Forrest AR |
Year: |
2003 |
Journal: |
Genome Res |
Title: |
Exploration of the cell-cycle genes found within the RIKEN FANTOM2 data set. |
Volume: |
13 |
Issue: |
6B |
Pages: |
1366-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guay-Woodford LM |
Year: |
2003 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Murine models of polycystic kidney disease: molecular and therapeutic insights. |
Volume: |
285 |
Issue: |
6 |
Pages: |
F1034-49 |
|
•
•
•
•
•
|
Publication |
First Author: |
Amin P |
Year: |
2018 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Regulation of a distinct activated RIPK1 intermediate bridging complex I and complex II in TNFα-mediated apoptosis. |
Volume: |
115 |
Issue: |
26 |
Pages: |
E5944-E5953 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory |
Year: |
2005 |
Journal: |
Unpublished |
Title: |
Information obtained from The Jackson Laboratory, Bar Harbor, ME |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Strausberg RL |
Year: |
2002 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |
Volume: |
99 |
Issue: |
26 |
Pages: |
16899-903 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Backcross DNA Panel Mapping Resource |
Year: |
1999 |
Journal: |
Database Release |
Title: |
JAX BSS Panel Mapping Data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators, MGI curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation based on Enzyme Commission mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GO Central curators, GOA curators, Rhea curators |
Year: |
2020 |
|
Title: |
Automatic Gene Ontology annotation based on Rhea mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2001 |
|
Title: |
RIKEN Data Curation in Mouse Genome Informatics |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ko MS |
Year: |
2000 |
Journal: |
Development |
Title: |
Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. |
Volume: |
127 |
Issue: |
8 |
Pages: |
1737-49 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2018 |
Journal: |
Database Release |
Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
QTL |
Type: |
QTL |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
QTL |
Type: |
QTL |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
206 |
Description: |
Phosphoserine; by NEK1 |
Type: |
modified residue |
End: |
206 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
572 |
Description: |
Phosphoserine; by NEK1 |
Type: |
modified residue |
End: |
572 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1 |
Description: |
Serine/threonine-protein kinase Nek1 |
Type: |
chain |
End: |
1203 |
|
•
•
•
•
•
|
QTL |
Type: |
QTL |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1203
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1231
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1178
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1275
|
Fragment?: |
false |
|
•
•
•
•
•
|
Allele |
Name: |
modifier of Nek1 (NIMA-related expressed kinase 1, hematocrit; C57BL/6J |
Allele Type: |
QTL |
|
|
•
•
•
•
•
|
Allele |
Name: |
modifier of Nek1 (NIMA-related expressed kinase 1, hematocrit; CAST/Ei |
Allele Type: |
QTL |
|
|
•
•
•
•
•
|
Allele |
Name: |
modifier of Nek1 (NIMA-related expressed kinase 1, kidney weight; CAST/Ei |
Allele Type: |
QTL |
|
|
•
•
•
•
•
|
Allele |
Name: |
modifier of Nek1 (NIMA-related expressed kinase 1, kidney weight; C57BL/6J |
Allele Type: |
QTL |
|
|
•
•
•
•
•
|
Interaction Experiment |
Description: |
Nek1 and TAZ interact to maintain normal levels of polycystin 2. |
|
•
•
•
•
•
|
Allele |
Name: |
modifier of Nek1 (NIMA-related expressed kinase 1), kidney weight and hematocrit; CAST/Ei |
Allele Type: |
QTL |
|
|
•
•
•
•
•
|
Allele |
Name: |
modifier of Nek1 (NIMA-related expressed kinase 1), kidney weight and hematocrit; C57BL/6J |
Allele Type: |
QTL |
|
|
•
•
•
•
•
|
Genotype |
Symbol: |
Mnek1c/Mnek1c |
Background: |
involves: C57BL/6J-Nek1/+ * CAST/Ei |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Mnek1b/Mnek1b |
Background: |
involves: C57BL/6J-Nek1/+ * CAST/Ei |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Mnek1a/Mnek1a |
Background: |
involves: C57BL/6J-Nek1/+ * CAST/Ei |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Allele |
Name: |
NIMA (never in mitosis gene a)-related expressed kinase 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Mnek1b/Mnek1b |
Background: |
involves: C57BL/6J-Nek1/+ * CAST/Ei |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Mnek1c/Mnek1c |
Background: |
involves: C57BL/6J-Nek1/+ * CAST/Ei |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Allele |
Name: |
NIMA (never in mitosis gene a)-related expressed kinase 1; endonuclease-mediated mutation 13, Cathy Lutz |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Humanized sequence |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant strain, endonuclease-mediated mutation, coisogenic |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This family includes Protein chibby homolog 2 (also known as Spermatid-associated protein). The function of this family is unclear. However, mouse spermatid-associated protein (SPERT, also known as Nurit) can form homodimers and can bind to NEK1 kinase. Its expression is restricted to the flower-like structure in spermatids []. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
446
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
419
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Hayashi K |
Year: |
1999 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Activity and substrate specificity of the murine STK2 Serine/Threonine kinase that is structurally related to the mitotic regulator protein NIMA of Aspergillus nidulans. |
Volume: |
264 |
Issue: |
2 |
Pages: |
449-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhu Y |
Year: |
2020 |
Journal: |
Mol Cell |
Title: |
Dynamic Regulation of ME1 Phosphorylation and Acetylation Affects Lipid Metabolism and Colorectal Tumorigenesis. |
Volume: |
77 |
Issue: |
1 |
Pages: |
138-149.e5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tanaka K |
Year: |
1999 |
Journal: |
J Biol Chem |
Title: |
Cloning and characterization of the murine Nek3 protein kinase, a novel member of the NIMA family of putative cell cycle regulators. |
Volume: |
274 |
Issue: |
19 |
Pages: |
13491-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Levedakou EN |
Year: |
1994 |
Journal: |
Oncogene |
Title: |
Two novel human serine/threonine kinases with homologies to the cell cycle regulating Xenopus MO15, and NIMA kinases: cloning and characterization of their expression pattern. |
Volume: |
9 |
Issue: |
7 |
Pages: |
1977-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ballif BA |
Year: |
2004 |
Journal: |
Mol Cell Proteomics |
Title: |
Phosphoproteomic analysis of the developing mouse brain. |
Volume: |
3 |
Issue: |
11 |
Pages: |
1093-101 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huttlin EL |
Year: |
2010 |
Journal: |
Cell |
Title: |
A tissue-specific atlas of mouse protein phosphorylation and expression. |
Volume: |
143 |
Issue: |
7 |
Pages: |
1174-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
Church DM |
Year: |
2009 |
Journal: |
PLoS Biol |
Title: |
Lineage-specific biology revealed by a finished genome assembly of the mouse. |
Volume: |
7 |
Issue: |
5 |
Pages: |
e1000112 |
|
•
•
•
•
•
|