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Search results 401 to 472 out of 472 for Rbl1

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Type Details Score
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Rbl1<tm1Htr> | MGI:2385659
Name: RB transcriptional corepressor like 1; targeted mutation 1, Hein te Riele
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Tg(WAPT121)66Tvd | MGI:4940590
Name: transgene insertion 66, Terry van Dyke
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Rbl1<tm1Mru> | MGI:1857798
Name: RB transcriptional corepressor like 1; targeted mutation 1, Michael Rudnicki
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:6144448 | B6D2-Tg(WAPT121)66Tvd/Nci
Attribute String: mutant stock, transgenic
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Allele
Rbl1<tm1Tyj> | MGI:1857448
Name: RB transcriptional corepressor like 1; targeted mutation 1, Tyler Jacks
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:3777354 | B6;129S2-Rbl1<tm1Tyj>/J
Attribute String: targeted mutation, mutant stock
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Genotype
Genotype
Symbol: Rbl1/Rbl1
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbl1/Rbl1<+>
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbl1/Rbl1
Background: involves: 129S2/SvPas
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbl1/Rbl1
Background: involves: 129S2/SvPas * FVB/N
Zygosity: hm
Has Mutant Allele: true
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Publication
23125361 | J:200246
First Author: Loedige I
Year: 2013
Journal: Nucleic Acids Res
Title: The mammalian TRIM-NHL protein TRIM71/LIN-41 is a repressor of mRNA function.
Volume: 41
Issue: 1
Pages: 518-32
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HT Experiment
E-GEOD-9567 | Transcription profiling of mouse whole skin from pRB deficient animals reveals that p107 acts as a tumor suppressor
Series Id: GSE9567
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
14966529 | J:88315
First Author: Simin K
Year: 2004
Journal: PLoS Biol
Title: pRb inactivation in mammary cells reveals common mechanisms for tumor initiation and progression in divergent epithelia.
Volume: 2
Issue: 2
Pages: E22
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1 Tg(Pcp2-cre)756Mro/?
Background: involves: 129P2/OlaHsd * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1 Tg(En2-cre)22Alj/?
Background: involves: 129P2/OlaHsd * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1<+> Tg(En2-cre)22Alj/?
Background: involves: 129P2/OlaHsd * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbl1/Rbl1
Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbl1/Rbl1
Background: involves: 129S4/SvJae * BALB/cJ
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbl1/Rbl1
Background: involves: 129S4/SvJae * BALB/c * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbl1/Rbl1
Background: involves: 129S4/SvJae * BALB/c
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1 Rbl2/Rbl2
Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Publication
21677172 | J:173537
First Author: Rocha-Sanchez SM
Year: 2011
Journal: J Neurosci
Title: Mature mice lacking Rbl2/p130 gene have supernumerary inner ear hair cells and supporting cells.
Volume: 31
Issue: 24
Pages: 8883-93
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1<+> Trp53/Trp53 Tg(En2-cre)22Alj/?
Background: involves: 129P2/OlaHsd * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbl1/Rbl1 Tg(Pax6-cre,GFP)2Pgr/?
Background: involves: 129 * C57BL/6 * FVB/N * NMRI
Zygosity: cn
Has Mutant Allele: true
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Publication
25907958 | J:316599
 
First Author: Xie C
Year: 2015
Journal: Mol Cancer
Title: Co-deleting Pten with Rb in retinal progenitor cells in mice results in fully penetrant bilateral retinoblastomas.
Volume: 14
Pages: 93
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Publication
12204530 | -
First Author: Sherr CJ
Year: 2002
Journal: Cancer Cell
Title: The RB and p53 pathways in cancer.
Volume: 2
Issue: 2
Pages: 103-12
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Publication
11545733 | -
First Author: Thomas DM
Year: 2001
Journal: Mol Cell
Title: The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation.
Volume: 8
Issue: 2
Pages: 303-16
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Protein Domain
IPR028309 | RB_fam
Type: Family
Description: This entry represents the retinoblastoma protein family, including retinoblastoma-associated protein (RB, also known as pRb, RB, p1051), retinoblastoma-like protein 1 (RBL1, also known as p107) and retinoblastoma-like protein 2 (RBL2, also known as RB2 or p130). Members of this family contain a conserved domain named the 'pocket' that interacts with the LXCXE motif found in viral proteins, such as SV40 large T antigen []. Therefore, this family is also called the pocket protein family.In humans, RB is a tumour suppressor linked to several major cancers []. RB forms complexes with E2Fs and represses gene expression by recruiting chromatin remodeling factors, such as histone deacetylases (HDACs) to E2F-responsive promoters [, ]. This interaction regulates genes necessary for DNA replication and cell cycle. Phosphorylation of RB family by CDK and cyclin complexes leads to release of the repressor complex and enables E2F-dependent gene expression []. Apart from E2Fs, RB also interacts with other transcription factors that govern cell differentiation [, ]. RBL1 and RBL2 are the components of the DREAM complex, which represses cell cycle-dependent genes in quiescent cells and plays a role in the cell cycle-dependent activation of G2/M genes [, ].
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Genotype
Genotype
Symbol: Rb1/Rb1<+> Rbl1/Rbl1
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbl1/Rbl1 Rbl2/Rbl2
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbl1/Rbl1<+> Rbl2/Rbl2
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbl1/Rbl1 Rbl2/Rbl2<+>
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1<+> Rbl1/Rbl1<+>
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1 Tg(Pax6-cre,GFP)2Pgr/?
Background: involves: 129S2/SvPas * 129S4/SvJae * 129X1/SvJ * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: E2f2/E2f2 Rbl1/Rbl1 Tg(Pax6-cre,GFP)2Pgr/?
Background: involves: 129 * C57BL/6 * FVB/N * NMRI
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: E2f1/E2f1<+> Rbl1/Rbl1 Tg(Pax6-cre,GFP)2Pgr/?
Background: involves: 129 * C57BL/6 * FVB/N * NMRI
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: E2f1/E2f1 Rbl1/Rbl1 Tg(Pax6-cre,GFP)2Pgr/?
Background: involves: 129 * C57BL/6 * FVB/N * NMRI
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: E2f3/E2f3 Rbl1/Rbl1 Tg(Pax6-cre,GFP)2Pgr/?
Background: involves: 129 * C57BL/6 * FVB/N * NMRI
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbl1/Rbl1 Tg(Chx10-EGFP/cre,-ALPP)2Clc/?
Background: involves: 129 * C57BL/6 * FVB/N * NMRI * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1 Tg(Nes-cre)1Atp/?
Background: involves: 129S2/SvPas * 129S4/SvJae * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1
Background: involves: 129S2/SvPas * 129S4/SvJae * BALB/c * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1 Rbl2/Rbl2
Background: involves: 129 * 129S2/SvPas * 129S4/SvJae
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbl1/Rbl1<+> Rbl2/Rbl2<+>
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1 Tg(KRT14-cre)8Brn/?
Background: involves: 129 * 129S2/SvPas * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Protein
Q62017
Organism: Mus musculus/domesticus
Length: 187  
Fragment?: true
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Publication
11018009 | -
First Author: Harbour JW
Year: 2000
Journal: Genes Dev
Title: The Rb/E2F pathway: expanding roles and emerging paradigms.
Volume: 14
Issue: 19
Pages: 2393-409
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Publication
6320372 | -
First Author: Murphree AL
Year: 1984
Journal: Science
Title: Retinoblastoma: clues to human oncogenesis.
Volume: 223
Issue: 4640
Pages: 1028-33
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Publication
21665145 | J:173563
First Author: Schvartzman JM
Year: 2011
Journal: Cancer Cell
Title: Mad2 is a critical mediator of the chromosome instability observed upon Rb and p53 pathway inhibition.
Volume: 19
Issue: 6
Pages: 701-14
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Genotype
Genotype
Symbol: E2f1/E2f1 E2f3/E2f3 Rbl1/Rbl1 Tg(Pax6-cre,GFP)2Pgr/?
Background: involves: 129 * C57BL/6 * FVB/N * NMRI
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1 Tg(Chx10-EGFP/cre,-ALPP)2Clc/?
Background: involves: 129 * C57BL/6N * SJL
Zygosity: cn
Has Mutant Allele: true
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Protein
Q9CT40
Organism: Mus musculus/domesticus
Length: 405  
Fragment?: true
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Protein
Q3UQT1
Organism: Mus musculus/domesticus
Length: 174  
Fragment?: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1 Trp53/Trp53 Tg(Chx10-EGFP/cre,-ALPP)2Clc/?
Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1 Trp53/Trp53 Tg(Chx10-EGFP/cre,-ALPP)2Clc/?
Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1<+> Trp53/Trp53 Tg(Chx10-EGFP/cre,-ALPP)2Clc/?
Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1<+> Tg(Chx10-EGFP/cre,-ALPP)2Clc/?
Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hells/Hells Rb1/Rb1 Rbl1/Rbl1 Tg(Chx10-EGFP/cre,-ALPP)2Clc/?
Background: involves: 129 * C57BL/6N * SJL
Zygosity: cn
Has Mutant Allele: true
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Protein
P13405
Organism: Mus musculus/domesticus
Length: 921  
Fragment?: false
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Protein
Q64700
Organism: Mus musculus/domesticus
Length: 1135  
Fragment?: false
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Protein
Q3URY9
Organism: Mus musculus/domesticus
Length: 921  
Fragment?: false
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Protein
Q3V0V3
Organism: Mus musculus/domesticus
Length: 549  
Fragment?: false
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Protein
Q8VCD1
Organism: Mus musculus/domesticus
Length: 1135  
Fragment?: false
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Protein
A0A1B0GR06
Organism: Mus musculus/domesticus
Length: 1125  
Fragment?: false
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Protein
Q3UJG1
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
A0A1B0GRM0
Organism: Mus musculus/domesticus
Length: 1092  
Fragment?: false
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Publication
17493263 | J:160877
First Author: Herschkowitz JI
Year: 2007
Journal: Genome Biol
Title: Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors.
Volume: 8
Issue: 5
Pages: R76
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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