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Search results 1 to 99 out of 99 for Rasgrp2

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
10235 | RASGRP2
Type: gene
Organism: human
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Gene
512056 | RASGRP2
Type: gene
Organism: cattle
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Gene
557063 | rasgrp2
Type: gene
Organism: zebrafish
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Gene
722044 | RASGRP2
Type: gene
Organism: macaque, rhesus
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Gene
101733706 | rasgrp2
Type: gene
Organism: frog, western clawed
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Gene
361714 | Rasgrp2
Type: gene
Organism: rat
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Gene
612101 | RASGRP2
Type: gene
Organism: dog, domestic
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Gene
451298 | RASGRP2
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1333849 | Rasgrp2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
31826978 | J:283554
 
First Author: Lee RH
Year: 2019
Journal: Sci Transl Med
Title: Impaired hemostatic activity of healthy transfused platelets in inherited and acquired platelet disorders: Mechanisms and implications.
Volume: 11
Issue: 522
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Protein Coding Gene
MGP_CAROLIEiJ_G0022609 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0024763 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0024729 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0024702 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0024729 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0024497 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1333849 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0025175 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0023969 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0024469 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0024596 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0024562 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0024682 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0024591 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0025223 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0023715 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0024031 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0014103 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0023520 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
9341881 | J:52725
First Author: Kedra D
Year: 1997
Journal: Hum Genet
Title: The germinal center kinase gene and a novel CDC25-like gene are located in the vicinity of the PYGM gene on 11q13.
Volume: 100
Issue: 5-6
Pages: 611-9
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Publication
15334074 | J:92864
First Author: Crittenden JR
Year: 2004
Journal: Nat Med
Title: CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation.
Volume: 10
Issue: 9
Pages: 982-6
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Publication
26771488 | J:230666
First Author: Freeman SA
Year: 2016
Journal: Cell
Title: Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis.
Volume: 164
Issue: 1-2
Pages: 128-140
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Publication
19628710 | J:152916
First Author: Stefanini L
Year: 2009
Journal: Blood
Title: CalDAG-GEFI is at the nexus of calcium-dependent platelet activation.
Volume: 114
Issue: 12
Pages: 2506-14
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Publication
20147317 | J:158714
First Author: Crittenden JR
Year: 2010
Journal: Hum Mol Genet
Title: CalDAG-GEFI down-regulation in the striatum as a neuroprotective change in Huntington's disease.
Volume: 19
Issue: 9
Pages: 1756-65
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Publication
34371144 | J:322215
 
First Author: Crittenden JR
Year: 2021
Journal: Neurobiol Dis
Title: CalDAG-GEFI mediates striatal cholinergic modulation of dendritic excitability, synaptic plasticity and psychomotor behaviors.
Volume: 158
Pages: 105473
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GXD Expression
GXD Expression
       
Probe: MGI:5292095
Assay Type: RT-PCR
Annotation Date: 2011-10-26
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1691024
Stage: TS24
Assay Id: MGI:5293510
Age: embryonic day 16.5
Specimen Label: None
Specimen Num: 1
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GXD Expression
GXD Expression
       
Probe: MGI:3776270
Assay Type: RT-PCR
Annotation Date: 2008-04-07
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:3776290
Age: embryonic day 13.0
Specimen Label: E13
Specimen Num: 3
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GXD Expression
GXD Expression
       
Probe: MGI:3776270
Assay Type: RT-PCR
Annotation Date: 2008-04-07
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:3776290
Age: embryonic day 17.0
Specimen Label: E17
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3776270
Assay Type: RT-PCR
Annotation Date: 2018-01-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6111382
Age: postnatal
Specimen Label: Balb/c Mouse
Detected: true
Specimen Num: 3
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Publication
9789079 | J:50543
First Author: Kawasaki H
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia.
Volume: 95
Issue: 22
Pages: 13278-83
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Publication
16357324 | J:131247
First Author: Bernardi B
Year: 2006
Journal: Blood
Title: The small GTPase Rap1b regulates the cross talk between platelet integrin alpha2beta1 and integrin alphaIIbbeta3.
Volume: 107
Issue: 7
Pages: 2728-35
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Publication
21652673 | J:309868
First Author: Stolla M
Year: 2011
Journal: Blood
Title: CalDAG-GEFI deficiency protects mice in a novel model of Fcγ RIIA-mediated thrombosis and thrombocytopenia.
Volume: 118
Issue: 4
Pages: 1113-20
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Publication
27903653 | J:240721
First Author: Battram AM
Year: 2017
Journal: J Biol Chem
Title: The Phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P3) Binder Rasa3 Regulates Phosphoinositide 3-kinase (PI3K)-dependent Integrin αIIbβ3 Outside-in Signaling.
Volume: 292
Issue: 5
Pages: 1691-1704
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Publication
19265824 | J:146753
First Author: Hidalgo A
Year: 2009
Journal: Nat Med
Title: When integrins fail to integrate.
Volume: 15
Issue: 3
Pages: 249-50
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Publication
17492052 | J:122618
First Author: Bergmeier W
Year: 2007
Journal: J Clin Invest
Title: Mice lacking the signaling molecule CalDAG-GEFI represent a model for leukocyte adhesion deficiency type III.
Volume: 117
Issue: 6
Pages: 1699-707
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Publication
21848641 | J:341173
First Author: Ahmad F
Year: 2011
Journal: J Thromb Haemost
Title: Relative contributions of stromal interaction molecule 1 and CalDAG-GEFI to calcium-dependent platelet activation and thrombosis.
Volume: 9
Issue: 10
Pages: 2077-86
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Publication
21700775 | J:176912
First Author: Fuchs TA
Year: 2011
Journal: Blood
Title: Histones induce rapid and profound thrombocytopenia in mice.
Volume: 118
Issue: 13
Pages: 3708-14
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Publication
12817022 | J:84006
First Author: Li L
Year: 2003
Journal: J Immunol
Title: Mast cells in airway hyporesponsive C3H/HeJ mice express a unique isoform of the signaling protein Ras guanine nucleotide releasing protein 4 that is unresponsive to diacylglycerol and phorbol esters.
Volume: 171
Issue: 1
Pages: 390-7
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Publication
20413728 | J:163946
First Author: Carbo C
Year: 2010
Journal: J Leukoc Biol
Title: Integrin-independent role of CalDAG-GEFI in neutrophil chemotaxis.
Volume: 88
Issue: 2
Pages: 313-9
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Publication
18544684 | J:138733
First Author: Cifuni SM
Year: 2008
Journal: Blood
Title: CalDAG-GEFI and protein kinase C represent alternative pathways leading to activation of integrin alphaIIbbeta3 in platelets.
Volume: 112
Issue: 5
Pages: 1696-703
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Publication
26988592 | J:246687
First Author: Boulaftali Y
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: CalDAG-GEFI Deficiency Reduces Atherosclerotic Lesion Development in Mice.
Volume: 36
Issue: 5
Pages: 792-9
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Publication
22075250 | J:195974
First Author: Stefanini L
Year: 2012
Journal: Arterioscler Thromb Vasc Biol
Title: Rap1-Rac1 circuits potentiate platelet activation.
Volume: 32
Issue: 2
Pages: 434-41
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Publication
20971951 | J:168407
First Author: Stolla M
Year: 2011
Journal: Blood
Title: The kinetics of αIIbβ3 activation determines the size and stability of thrombi in mice: implications for antiplatelet therapy.
Volume: 117
Issue: 3
Pages: 1005-13
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Publication
21480213 | J:177314
First Author: Stadtmann A
Year: 2011
Journal: Eur J Immunol
Title: Rap1a activation by CalDAG-GEFI and p38 MAPK is involved in E-selectin-dependent slow leukocyte rolling.
Volume: 41
Issue: 7
Pages: 2074-85
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Publication
24585775 | J:210743
First Author: Stefanini L
Year: 2014
Journal: Blood
Title: A talin mutant that impairs talin-integrin binding in platelets decelerates αIIbβ3 activation without pathological bleeding.
Volume: 123
Issue: 17
Pages: 2722-31
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Publication
18172297 | J:131036
First Author: Ikuta S
Year: 2008
Journal: Cancer Res
Title: Crucial role of phospholipase C epsilon in skin inflammation induced by tumor-promoting phorbol ester.
Volume: 68
Issue: 1
Pages: 64-72
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Publication
25705885 | J:221899
First Author: Stefanini L
Year: 2015
Journal: J Clin Invest
Title: RASA3 is a critical inhibitor of RAP1-dependent platelet activation.
Volume: 125
Issue: 4
Pages: 1419-32
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Publication
29925524 | J:341082
First Author: Casari C
Year: 2018
Journal: Blood Adv
Title: Protein kinase C signaling dysfunction in von Willebrand disease (p.V1316M) type 2B platelets.
Volume: 2
Issue: 12
Pages: 1417-1428
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Publication
18256319 | J:135316
First Author: Goerge T
Year: 2008
Journal: Blood
Title: Inflammation induces hemorrhage in thrombocytopenia.
Volume: 111
Issue: 10
Pages: 4958-64
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Publication
26494785 | J:226616
First Author: Araujo DJ
Year: 2015
Journal: Genes Dev
Title: FoxP1 orchestration of ASD-relevant signaling pathways in the striatum.
Volume: 29
Issue: 20
Pages: 2081-96
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Publication
23359859 | J:198011
 
First Author: Eom T
Year: 2013
Journal: Elife
Title: NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure.
Volume: 2
Pages: e00178
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Publication
15142957 | J:174497
First Author: Funatsu N
Year: 2004
Journal: Cereb Cortex
Title: Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes.
Volume: 14
Issue: 9
Pages: 1031-44
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Publication
32170006 | J:286635
First Author: Chen SY
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Parcellation of the striatal complex into dorsal and ventral districts.
Volume: 117
Issue: 13
Pages: 7418-7429
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Allele
Rasgrp2<em1Smoc> | MGI:7291980
Name: RAS, guanyl releasing protein 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6476145 | C57BL/6-Rasgrp2<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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DO Term
DOID:0111051 | platelet-type bleeding disorder 18
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Publication
26804993 | J:259656
First Author: Nagai T
Year: 2016
Journal: Neuron
Title: Phosphoproteomics of the Dopamine Pathway Enables Discovery of Rap1 Activation as a Reward Signal In Vivo.
Volume: 89
Issue: 3
Pages: 550-65
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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