Type |
Details |
Score |
Publication |
First Author: |
Pan B |
Year: |
2019 |
Journal: |
Front Physiol |
Title: |
Highly Dynamic Changes in the Activity and Regulation of Macroautophagy in Hearts Subjected to Increased Proteotoxic Stress. |
Volume: |
10 |
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Pages: |
758 |
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•
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Publication |
First Author: |
Getz SA |
Year: |
2016 |
Journal: |
Neurobiol Dis |
Title: |
Rapamycin prevents, but does not reverse, aberrant migration in Pten knockout neurons. |
Volume: |
93 |
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Pages: |
12-20 |
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•
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•
•
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Publication |
First Author: |
Barrows CM |
Year: |
2017 |
Journal: |
J Neurosci |
Title: |
PTEN Loss Increases the Connectivity of Fast Synaptic Motifs and Functional Connectivity in a Developing Hippocampal Network. |
Volume: |
37 |
Issue: |
36 |
Pages: |
8595-8611 |
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•
•
•
•
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Publication |
First Author: |
Domènech-Estévez E |
Year: |
2016 |
Journal: |
J Neurosci |
Title: |
Akt Regulates Axon Wrapping and Myelin Sheath Thickness in the PNS. |
Volume: |
36 |
Issue: |
16 |
Pages: |
4506-21 |
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•
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•
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Publication |
First Author: |
Wang S |
Year: |
2019 |
Journal: |
Autophagy |
Title: |
Impaired TFEB-mediated lysosomal biogenesis promotes the development of pancreatitis in mice and is associated with human pancreatitis. |
Volume: |
15 |
Issue: |
11 |
Pages: |
1954-1969 |
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•
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•
•
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Publication |
First Author: |
Megat S |
Year: |
2019 |
Journal: |
J Neurosci |
Title: |
Differences between dorsal root and trigeminal ganglion nociceptors in mice revealed by translational profiling. |
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Publication |
First Author: |
Iwasaki K |
Year: |
2023 |
Journal: |
Front Endocrinol (Lausanne) |
Title: |
Decreased IGF1R attenuates senescence and improves function in pancreatic β-cells. |
Volume: |
14 |
|
Pages: |
1203534 |
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•
•
•
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Publication |
First Author: |
Rhine MA |
Year: |
2019 |
Journal: |
Autism Res |
Title: |
Hypothesis-driven investigations of diverse pharmacological targets in two mouse models of autism. |
Volume: |
12 |
Issue: |
3 |
Pages: |
401-421 |
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Publication |
First Author: |
Wan H |
Year: |
2020 |
Journal: |
Autophagy |
Title: |
WDR45 contributes to neurodegeneration through regulation of ER homeostasis and neuronal death. |
Volume: |
16 |
Issue: |
3 |
Pages: |
531-547 |
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•
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Publication |
First Author: |
Wang L |
Year: |
2022 |
Journal: |
Autophagy |
Title: |
Torin 1 alleviates impairment of TFEB-mediated lysosomal biogenesis and autophagy in TGFBI (p.G623_H626del)-linked Thiel-Behnke corneal dystrophy. |
Volume: |
18 |
Issue: |
4 |
Pages: |
765-782 |
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Publication |
First Author: |
Nordströma U |
Year: |
2015 |
Journal: |
Neurobiol Dis |
Title: |
Progressive nigrostriatal terminal dysfunction and degeneration in the engrailed1 heterozygous mouse model of Parkinson's disease. |
Volume: |
73 |
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Pages: |
70-82 |
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Publication |
First Author: |
Ding J |
Year: |
2018 |
Journal: |
Front Genet |
Title: |
Aberrant Protein Turn-Over Associated With Myofibrillar Disorganization in FHL1 Knockout Mice. |
Volume: |
9 |
|
Pages: |
273 |
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Publication |
First Author: |
Fedeli C |
Year: |
2019 |
Journal: |
Autophagy |
Title: |
PSEN2 (presenilin 2) mutants linked to familial Alzheimer disease impair autophagy by altering Ca2+ homeostasis. |
Volume: |
15 |
Issue: |
12 |
Pages: |
2044-2062 |
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•
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Publication |
First Author: |
Chao X |
Year: |
2021 |
Journal: |
J Hepatol |
Title: |
Hepatocytic p62 suppresses ductular reaction and tumorigenesis in mouse livers with mTORC1 activation and defective autophagy. |
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Publication |
First Author: |
Tao R |
Year: |
2015 |
Journal: |
Diabetes |
Title: |
Sestrin 3 protein enhances hepatic insulin sensitivity by direct activation of the mTORC2-Akt signaling. |
Volume: |
64 |
Issue: |
4 |
Pages: |
1211-23 |
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Publication |
First Author: |
Tan H |
Year: |
2017 |
Journal: |
Immunity |
Title: |
Integrative Proteomics and Phosphoproteomics Profiling Reveals Dynamic Signaling Networks and Bioenergetics Pathways Underlying T Cell Activation. |
Volume: |
46 |
Issue: |
3 |
Pages: |
488-503 |
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Publication |
First Author: |
Newton RH |
Year: |
2018 |
Journal: |
Nat Immunol |
Title: |
Maintenance of CD4 T cell fitness through regulation of Foxo1. |
Volume: |
19 |
Issue: |
8 |
Pages: |
838-848 |
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Publication |
First Author: |
Menk AV |
Year: |
2018 |
Journal: |
Cell Rep |
Title: |
Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions. |
Volume: |
22 |
Issue: |
6 |
Pages: |
1509-1521 |
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Publication |
First Author: |
Xiao M |
Year: |
2017 |
Journal: |
Blood |
Title: |
Osteoblasts support megakaryopoiesis through production of interleukin-9. |
Volume: |
129 |
Issue: |
24 |
Pages: |
3196-3209 |
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Publication |
First Author: |
Canaud G |
Year: |
2019 |
Journal: |
Sci Transl Med |
Title: |
Cyclin G1 and TASCC regulate kidney epithelial cell G2-M arrest and fibrotic maladaptive repair. |
Volume: |
11 |
Issue: |
476 |
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Publication |
First Author: |
Artinian J |
Year: |
2019 |
Journal: |
J Neurosci |
Title: |
Regulation of Hippocampal Memory by mTORC1 in Somatostatin Interneurons. |
Volume: |
39 |
Issue: |
43 |
Pages: |
8439-8456 |
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Publication |
First Author: |
Zhang X |
Year: |
2018 |
Journal: |
Cell Rep |
Title: |
Adipose mTORC1 Suppresses Prostaglandin Signaling and Beige Adipogenesis via the CRTC2-COX-2 Pathway. |
Volume: |
24 |
Issue: |
12 |
Pages: |
3180-3193 |
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Publication |
First Author: |
Iskarpatyoti JA |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
Mast cell regranulation requires a metabolic switch involving mTORC1 and a glucose-6-phosphate transporter. |
Volume: |
40 |
Issue: |
13 |
Pages: |
111346 |
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Publication |
First Author: |
Jiang M |
Year: |
2017 |
Journal: |
J Cell Biochem |
Title: |
mTORC1 Signaling Promotes Limb Bud Cell Growth and Chondrogenesis. |
Volume: |
118 |
Issue: |
4 |
Pages: |
748-753 |
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First Author: |
Wiebe S |
Year: |
2023 |
Journal: |
Mol Brain |
Title: |
Cell-type-specific translational control of spatial working memory by the cap-binding protein 4EHP. |
Volume: |
16 |
Issue: |
1 |
Pages: |
9 |
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First Author: |
Asgarihafshejani A |
Year: |
2022 |
Journal: |
iScience |
Title: |
Long-term potentiation at pyramidal cell to somatostatin interneuron synapses controls hippocampal network plasticity and memory. |
Volume: |
25 |
Issue: |
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104259 |
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First Author: |
Huang B |
Year: |
2016 |
Journal: |
Nat Commun |
Title: |
Osteoblasts secrete Cxcl9 to regulate angiogenesis in bone. |
Volume: |
7 |
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Riahi Y |
Year: |
2023 |
Journal: |
Diabetologia |
Title: |
Hyperglucagonaemia in diabetes: altered amino acid metabolism triggers mTORC1 activation, which drives glucagon production. |
Volume: |
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1925-1942 |
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First Author: |
Wang M |
Year: |
2017 |
Journal: |
Mol Cell Proteomics |
Title: |
The Glial Cell-Derived Neurotrophic Factor (GDNF)-responsive Phosphoprotein Landscape Identifies Raptor Phosphorylation Required for Spermatogonial Progenitor Cell Proliferation. |
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First Author: |
Haller S |
Year: |
2017 |
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Cell Stem Cell |
Title: |
mTORC1 Activation during Repeated Regeneration Impairs Somatic Stem Cell Maintenance. |
Volume: |
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First Author: |
Hu Y |
Year: |
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J Biol Chem |
Title: |
Fructose and glucose can regulate mammalian target of rapamycin complex 1 and lipogenic gene expression via distinct pathways. |
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AKT2 is essential to maintain podocyte viability and function during chronic kidney disease. |
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Year: |
2011 |
Journal: |
Cell Death Differ |
Title: |
The TSC1 and TSC2 tumor suppressors are required for proper ER stress response and protect cells from ER stress-induced apoptosis. |
Volume: |
18 |
Issue: |
1 |
Pages: |
133-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Akgül S |
Year: |
2018 |
Journal: |
Cell Rep |
Title: |
Opposing Tumor-Promoting and -Suppressive Functions of Rictor/mTORC2 Signaling in Adult Glioma and Pediatric SHH Medulloblastoma. |
Volume: |
24 |
Issue: |
2 |
Pages: |
463-478.e5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nobs SP |
Year: |
2015 |
Journal: |
Immunity |
Title: |
PI3-Kinase-γ Has a Distinct and Essential Role in Lung-Specific Dendritic Cell Development. |
Volume: |
43 |
Issue: |
4 |
Pages: |
674-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
Venkatesh A |
Year: |
2015 |
Journal: |
J Clin Invest |
Title: |
Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice. |
Volume: |
125 |
Issue: |
4 |
Pages: |
1446-58 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
525
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
392
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Wolff NC |
Year: |
2011 |
Journal: |
Mol Cell Biol |
Title: |
Cell-type-dependent regulation of mTORC1 by REDD1 and the tumor suppressors TSC1/TSC2 and LKB1 in response to hypoxia. |
Volume: |
31 |
Issue: |
9 |
Pages: |
1870-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ruegsegger C |
Year: |
2016 |
Journal: |
Neuron |
Title: |
Impaired mTORC1-Dependent Expression of Homer-3 Influences SCA1 Pathophysiology. |
Volume: |
89 |
Issue: |
1 |
Pages: |
129-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Charbonnier LM |
Year: |
2015 |
Journal: |
Nat Immunol |
Title: |
Control of peripheral tolerance by regulatory T cell-intrinsic Notch signaling. |
Volume: |
16 |
Issue: |
11 |
Pages: |
1162-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Imanishi T |
Year: |
2019 |
Journal: |
Life Sci Alliance |
Title: |
Reciprocal regulation of STING and TCR signaling by mTORC1 for T-cell activation and function. |
Volume: |
2 |
Issue: |
1 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Rodgers JT |
Year: |
2014 |
Journal: |
Nature |
Title: |
mTORC1 controls the adaptive transition of quiescent stem cells from G0 to G(Alert). |
Volume: |
510 |
Issue: |
7505 |
Pages: |
393-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu C |
Year: |
2021 |
Journal: |
Sci Adv |
Title: |
Glycogen synthase kinase 3 drives thymocyte egress by suppressing β-catenin activation of Akt. |
Volume: |
7 |
Issue: |
41 |
Pages: |
eabg6262 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yi W |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
The mTORC1-4E-BP-eIF4E axis controls de novo Bcl6 protein synthesis in T cells and systemic autoimmunity. |
Volume: |
8 |
Issue: |
1 |
Pages: |
254 |
|
•
•
•
•
•
|
Publication |
First Author: |
Asrani K |
Year: |
2019 |
Journal: |
J Clin Invest |
Title: |
mTORC1 feedback to AKT modulates lysosomal biogenesis through MiT/TFE regulation. |
Volume: |
129 |
Issue: |
12 |
Pages: |
5584-5599 |
|
•
•
•
•
•
|
Publication |
First Author: |
Van Nostrand JL |
Year: |
2020 |
Journal: |
Genes Dev |
Title: |
AMPK regulation of Raptor and TSC2 mediate metformin effects on transcriptional control of anabolism and inflammation. |
Volume: |
34 |
Issue: |
19-20 |
Pages: |
1330-1344 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee PY |
Year: |
2017 |
Journal: |
Sci Immunol |
Title: |
The metabolic regulator mTORC1 controls terminal myeloid differentiation. |
Volume: |
2 |
Issue: |
11 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
McGuire VA |
Year: |
2013 |
Journal: |
Mol Cell Biol |
Title: |
Cross talk between the Akt and p38α pathways in macrophages downstream of Toll-like receptor signaling. |
Volume: |
33 |
Issue: |
21 |
Pages: |
4152-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang T |
Year: |
2016 |
Journal: |
Cell Mol Immunol |
Title: |
TSC1 controls IL-1β expression in macrophages via mTORC1-dependent C/EBPβ pathway. |
Volume: |
13 |
Issue: |
5 |
Pages: |
640-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Feng D |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
mTORC1 Down-Regulates Cyclin-Dependent Kinase 8 (CDK8) and Cyclin C (CycC). |
Volume: |
10 |
Issue: |
6 |
Pages: |
e0126240 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yousefi M |
Year: |
2018 |
Journal: |
Stem Cell Reports |
Title: |
Calorie Restriction Governs Intestinal Epithelial Regeneration through Cell-Autonomous Regulation of mTORC1 in Reserve Stem Cells. |
Volume: |
10 |
Issue: |
3 |
Pages: |
703-711 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang H |
Year: |
2019 |
Journal: |
Cell Death Dis |
Title: |
AKT-dependent and -independent pathways mediate PTEN deletion-induced CNS axon regeneration. |
Volume: |
10 |
Issue: |
3 |
Pages: |
203 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fu X |
Year: |
2018 |
Journal: |
J Clin Invest |
Title: |
Tuberous sclerosis complex-mediated mTORC1 overactivation promotes age-related hearing loss. |
Volume: |
128 |
Issue: |
11 |
Pages: |
4938-4955 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jones I |
Year: |
2019 |
Journal: |
Biol Open |
Title: |
Reduced mTORC1-signalling in retinal progenitor cells leads to visual pathway dysfunction. |
Volume: |
8 |
Issue: |
8 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Huynh H |
Year: |
2018 |
Journal: |
Commun Biol |
Title: |
mTORC1 impedes osteoclast differentiation via calcineurin and NFATc1. |
Volume: |
1 |
|
Pages: |
29 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xiang H |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
Vps33B controls Treg cell suppressive function through inhibiting lysosomal nutrient sensing complex-mediated mTORC1 activation. |
Volume: |
39 |
Issue: |
11 |
Pages: |
110943 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gosis BS |
Year: |
2022 |
Journal: |
Science |
Title: |
Inhibition of nonalcoholic fatty liver disease in mice by selective inhibition of mTORC1. |
Volume: |
376 |
Issue: |
6590 |
Pages: |
eabf8271 |
|
•
•
•
•
•
|
Publication |
First Author: |
Martinez Calejman C |
Year: |
2020 |
Journal: |
Nat Commun |
Title: |
mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis. |
Volume: |
11 |
Issue: |
1 |
Pages: |
575 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shrestha S |
Year: |
2015 |
Journal: |
Nat Immunol |
Title: |
Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses. |
Volume: |
16 |
Issue: |
2 |
Pages: |
178-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Signer RA |
Year: |
2014 |
Journal: |
Nature |
Title: |
Haematopoietic stem cells require a highly regulated protein synthesis rate. |
Volume: |
509 |
Issue: |
7498 |
Pages: |
49-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gu Y |
Year: |
2011 |
Journal: |
Diabetes |
Title: |
Rictor/mTORC2 is essential for maintaining a balance between beta-cell proliferation and cell size. |
Volume: |
60 |
Issue: |
3 |
Pages: |
827-37 |
|
•
•
•
•
•
|