Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
430
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7461634 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-04-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7466102 |
Age: |
postnatal week 6 |
|
|
Specimen Label: |
E2F1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4839153 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2010-11-19 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757727 |
Pattern: |
Single cells |
Stage: |
TS27 |
Assay Id: |
MGI:4839209 |
Age: |
postnatal day 0 |
Image: |
2A - E2f1 |
Note: |
Expression is present in oligodendrocytes and oligoendrocyte progenitors. |
Specimen Label: |
2A - E2f1 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Grouwels G |
Year: |
2010 |
Journal: |
Diabetes |
Title: |
Ectopic expression of E2F1 stimulates beta-cell proliferation and function. |
Volume: |
59 |
Issue: |
6 |
Pages: |
1435-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Russell JL |
Year: |
2002 |
Journal: |
Mol Cell Biol |
Title: |
ARF differentially modulates apoptosis induced by E2F1 and Myc. |
Volume: |
22 |
Issue: |
5 |
Pages: |
1360-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lazzerini Denchi E |
Year: |
2005 |
Journal: |
EMBO Rep |
Title: |
E2F1 is crucial for E2F-dependent apoptosis. |
Volume: |
6 |
Issue: |
7 |
Pages: |
661-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ladu S |
Year: |
2008 |
Journal: |
Gastroenterology |
Title: |
E2F1 inhibits c-Myc-driven apoptosis via PIK3CA/Akt/mTOR and COX-2 in a mouse model of human liver cancer. |
Volume: |
135 |
Issue: |
4 |
Pages: |
1322-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li Y |
Year: |
1994 |
Journal: |
Mol Cell Biol |
Title: |
Cloning, chromosomal location, and characterization of mouse E2F1. |
Volume: |
14 |
Issue: |
3 |
Pages: |
1861-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Russell JL |
Year: |
2006 |
Journal: |
Oncogene |
Title: |
E2F1 suppresses skin carcinogenesis via the ARF-p53 pathway. |
Volume: |
25 |
Issue: |
6 |
Pages: |
867-76 |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
ArrayExpress |
|
•
•
•
•
•
|
Publication |
First Author: |
Raimundo N |
Year: |
2012 |
Journal: |
Cell |
Title: |
Mitochondrial stress engages E2F1 apoptotic signaling to cause deafness. |
Volume: |
148 |
Issue: |
4 |
Pages: |
716-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pierce AM |
Year: |
1999 |
Journal: |
Mol Cell Biol |
Title: |
E2F1 has both oncogenic and tumor-suppressive properties in a transgenic model. |
Volume: |
19 |
Issue: |
9 |
Pages: |
6408-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang D |
Year: |
2000 |
Journal: |
Mol Cell Biol |
Title: |
E2F4 and E2F1 have similar proliferative properties but different apoptotic and oncogenic properties in vivo. |
Volume: |
20 |
Issue: |
10 |
Pages: |
3417-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Holmberg C |
Year: |
1998 |
Journal: |
Oncogene |
Title: |
E2F-1-induced p53-independent apoptosis in transgenic mice. |
Volume: |
17 |
Issue: |
2 |
Pages: |
143-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pierce AM |
Year: |
1998 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Increased E2F1 activity induces skin tumors in mice heterozygous and nullizygous for p53. |
Volume: |
95 |
Issue: |
15 |
Pages: |
8858-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bourouh C |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
The transcription factor E2F1 controls the GLP-1 receptor pathway in pancreatic β cells. |
Volume: |
40 |
Issue: |
6 |
Pages: |
111170 |
|
•
•
•
•
•
|
Publication |
First Author: |
Giralt A |
Year: |
2018 |
Journal: |
Mol Metab |
Title: |
E2F1 promotes hepatic gluconeogenesis and contributes to hyperglycemia during diabetes. |
Volume: |
11 |
|
Pages: |
104-112 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fedele M |
Year: |
2006 |
Journal: |
Cancer Cell |
Title: |
HMGA2 induces pituitary tumorigenesis by enhancing E2F1 activity. |
Volume: |
9 |
Issue: |
6 |
Pages: |
459-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Costa C |
Year: |
2013 |
Journal: |
Oncogene |
Title: |
E2F1 loss induces spontaneous tumour development in Rb-deficient epidermis. |
Volume: |
32 |
Issue: |
24 |
Pages: |
2937-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hou ST |
Year: |
2000 |
Journal: |
J Neurochem |
Title: |
The transcription factor E2F1 modulates apoptosis of neurons. |
Volume: |
75 |
Issue: |
1 |
Pages: |
91-100 |
|
•
•
•
•
•
|
Publication |
First Author: |
Conner EA |
Year: |
2003 |
Journal: |
Biochem Biophys Res Commun |
Title: |
E2F1 blocks and c-Myc accelerates hepatic ploidy in transgenic mouse models. |
Volume: |
302 |
Issue: |
1 |
Pages: |
114-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang B |
Year: |
2015 |
Journal: |
Nat Commun |
Title: |
POH1 deubiquitylates and stabilizes E2F1 to promote tumour formation. |
Volume: |
6 |
|
Pages: |
8704 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bartley SM |
Year: |
1998 |
Journal: |
Gene |
Title: |
Characterization of the 3' untranslated region of mouse E2F1 mRNA. |
Volume: |
223 |
Issue: |
1-2 |
Pages: |
355-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang L |
Year: |
2007 |
Journal: |
J Neurosci |
Title: |
E2F1 works as a cell cycle suppressor in mature neurons. |
Volume: |
27 |
Issue: |
46 |
Pages: |
12555-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dassanayaka S |
Year: |
2019 |
Journal: |
Basic Res Cardiol |
Title: |
E2f1 deletion attenuates infarct-induced ventricular remodeling without affecting O-GlcNAcylation. |
Volume: |
114 |
Issue: |
4 |
Pages: |
28 |
|
•
•
•
•
•
|
Publication |
First Author: |
Denechaud PD |
Year: |
2016 |
Journal: |
J Clin Invest |
Title: |
E2F1 mediates sustained lipogenesis and contributes to hepatic steatosis. |
Volume: |
126 |
Issue: |
1 |
Pages: |
137-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rounbehler RJ |
Year: |
2002 |
Journal: |
Cancer Res |
Title: |
Inactivation of E2f1 enhances tumorigenesis in a Myc transgenic model. |
Volume: |
62 |
Issue: |
11 |
Pages: |
3276-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lu Z |
Year: |
2014 |
Journal: |
Nat Commun |
Title: |
Skp2 suppresses apoptosis in Rb1-deficient tumours by limiting E2F1 activity. |
Volume: |
5 |
|
Pages: |
3463 |
|
•
•
•
•
•
|
Publication |
First Author: |
Berton TR |
Year: |
2005 |
Journal: |
Oncogene |
Title: |
Regulation of epidermal apoptosis and DNA repair by E2F1 in response to ultraviolet B radiation. |
Volume: |
24 |
Issue: |
15 |
Pages: |
2449-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu M |
Year: |
2014 |
Journal: |
Cardiovasc Res |
Title: |
E2F1 suppresses cardiac neovascularization by down-regulating VEGF and PlGF expression. |
Volume: |
104 |
Issue: |
3 |
Pages: |
412-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kent LN |
Year: |
2017 |
Journal: |
J Clin Invest |
Title: |
Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma. |
Volume: |
127 |
Issue: |
3 |
Pages: |
830-842 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wolfram JA |
Year: |
2011 |
Journal: |
Int J Clin Exp Pathol |
Title: |
The role of E2F1 in the development of hypertrophic cardiomyopathy. |
Volume: |
4 |
Issue: |
5 |
Pages: |
521-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen D |
Year: |
2013 |
Journal: |
Cell Death Differ |
Title: |
E2f2 induces cone photoreceptor apoptosis independent of E2f1 and E2f3. |
Volume: |
20 |
Issue: |
7 |
Pages: |
931-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baudino TA |
Year: |
2003 |
Journal: |
Mol Cell |
Title: |
Myc-mediated proliferation and lymphomagenesis, but not apoptosis, are compromised by E2f1 loss. |
Volume: |
11 |
Issue: |
4 |
Pages: |
905-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carnevale J |
Year: |
2012 |
Journal: |
Mol Cell Biol |
Title: |
DNA damage signals through differentially modified E2F1 molecules to induce apoptosis. |
Volume: |
32 |
Issue: |
5 |
Pages: |
900-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pellicano F |
Year: |
2018 |
Journal: |
Blood |
Title: |
hsa-mir183/EGR1-mediated regulation of E2F1 is required for CML stem/progenitor cell survival. |
Volume: |
131 |
Issue: |
14 |
Pages: |
1532-1544 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rotgers E |
Year: |
2015 |
Journal: |
Andrology |
Title: |
E2F1 controls germ cell apoptosis during the first wave of spermatogenesis. |
Volume: |
3 |
Issue: |
5 |
Pages: |
1000-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ting JH |
Year: |
2014 |
Journal: |
J Neurochem |
Title: |
Targeted gene mutation of E2F1 evokes age-dependent synaptic disruption and behavioral deficits. |
Volume: |
129 |
Issue: |
5 |
Pages: |
850-63 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6171655 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689419 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:6190165 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
Table S2 - E11.5 - E2f1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6171655 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:6190165 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Table S2 - E13.5 - E2f1 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6171655 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689424 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6190165 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Table S2 - E15.5 - E2f1 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6171655 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689426 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:6190165 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
Table S2 - E18.5 - E2f1 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6171655 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190165 |
Age: |
postnatal day 4 |
|
|
Specimen Label: |
Table S2 - P4 - E2f1 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6171655 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190165 |
Age: |
postnatal day 14 |
|
|
Specimen Label: |
Table S2 - P14 - E2f1 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6171655 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190165 |
Age: |
postnatal day 28 |
|
|
Specimen Label: |
Table S2 - P28 - E2f1 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miyajima M |
Year: |
1996 |
Journal: |
J Neurosci Res |
Title: |
Overexpression of E2F1 in astrocytes leads to neoplastic transformation and changes in expression of retinoblastoma family members. |
Volume: |
46 |
Issue: |
1 |
Pages: |
108-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zacksenhaus E |
Year: |
1996 |
Journal: |
EMBO J |
Title: |
Dual mechanisms of repression of E2F1 activity by the retinoblastoma gene product. |
Volume: |
15 |
Issue: |
21 |
Pages: |
5917-27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lin SC |
Year: |
2001 |
Journal: |
Oncogene |
Title: |
The proliferative and apoptotic activities of E2F1 in the mouse retina. |
Volume: |
20 |
Issue: |
48 |
Pages: |
7073-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jorgez CJ |
Year: |
2021 |
Journal: |
Development |
Title: |
E2F1 regulates testicular descent and controls spermatogenesis by influencing WNT4 signaling. |
Volume: |
148 |
Issue: |
1 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Lai Q |
Year: |
2017 |
Journal: |
JCI Insight |
Title: |
E2F1 inhibits circulating cholesterol clearance by regulating Pcsk9 expression in the liver. |
Volume: |
2 |
Issue: |
10 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
González-Romero F |
Year: |
2021 |
Journal: |
Cancer Res |
Title: |
E2F1 and E2F2-Mediated Repression of CPT2 Establishes a Lipid-Rich Tumor-Promoting Environment. |
Volume: |
81 |
Issue: |
11 |
Pages: |
2874-2887 |
|
•
•
•
•
•
|
Publication |
First Author: |
Manickavinayaham S |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
E2F1 acetylation directs p300/CBP-mediated histone acetylation at DNA double-strand breaks to facilitate repair. |
Volume: |
10 |
Issue: |
1 |
Pages: |
4951 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tarangelo A |
Year: |
2015 |
Journal: |
Nat Commun |
Title: |
Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression. |
Volume: |
6 |
|
Pages: |
10028 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wikonkal NM |
Year: |
2003 |
Journal: |
Nat Cell Biol |
Title: |
Inactivating E2f1 reverts apoptosis resistance and cancer sensitivity in Trp53-deficient mice. |
Volume: |
5 |
Issue: |
7 |
Pages: |
655-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Biswas AK |
Year: |
2014 |
Journal: |
Cancer Res |
Title: |
E2F1 responds to ultraviolet radiation by directly stimulating DNA repair and suppressing carcinogenesis. |
Volume: |
74 |
Issue: |
12 |
Pages: |
3369-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
GarcÃa I |
Year: |
2000 |
Journal: |
Cell Growth Differ |
Title: |
A role for E2F1 in the induction of apoptosis during thymic negative selection. |
Volume: |
11 |
Issue: |
2 |
Pages: |
91-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xiong M |
Year: |
2021 |
Journal: |
Front Physiol |
Title: |
Transcription Factor E2F1 Knockout Promotes Mice White Adipose Tissue Browning Through Autophagy Inhibition. |
Volume: |
12 |
|
Pages: |
748040 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hsiao KM |
Year: |
1994 |
Journal: |
Genes Dev |
Title: |
Multiple DNA elements are required for the growth regulation of the mouse E2F1 promoter. |
Volume: |
8 |
Issue: |
13 |
Pages: |
1526-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hyde RK |
Year: |
2002 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Unique roles for E2F1 in the mouse lens in the absence of functional pRB proteins. |
Volume: |
43 |
Issue: |
5 |
Pages: |
1509-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Warg LA |
Year: |
2012 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
The role of the E2F1 transcription factor in the innate immune response to systemic LPS. |
Volume: |
303 |
Issue: |
5 |
Pages: |
L391-400 |
|
•
•
•
•
•
|
Publication |
First Author: |
Salam MA |
Year: |
2004 |
Journal: |
J Immunol |
Title: |
E2f1 mutation induces early onset of diabetes and Sjögren's syndrome in nonobese diabetic mice. |
Volume: |
173 |
Issue: |
8 |
Pages: |
4908-18 |
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Publication |
First Author: |
Iglesias-Ara A |
Year: |
2015 |
Journal: |
Cell Death Differ |
Title: |
E2F1 and E2F2 prevent replicative stress and subsequent p53-dependent organ involution. |
Volume: |
22 |
Issue: |
10 |
Pages: |
1577-89 |
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Publication |
First Author: |
Zhu JW |
Year: |
2001 |
Journal: |
Mol Cell Biol |
Title: |
E2F1 and E2F2 determine thresholds for antigen-induced T-cell proliferation and suppress tumorigenesis. |
Volume: |
21 |
Issue: |
24 |
Pages: |
8547-64 |
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Publication |
First Author: |
Pan H |
Year: |
1998 |
Journal: |
Mol Cell |
Title: |
Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors. |
Volume: |
2 |
Issue: |
3 |
Pages: |
283-92 |
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Publication |
First Author: |
Zhu JW |
Year: |
1999 |
Journal: |
Cell Growth Differ |
Title: |
A role for E2F1 in the induction of ARF, p53, and apoptosis during thymic negative selection. |
Volume: |
10 |
Issue: |
12 |
Pages: |
829-38 |
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Publication |
First Author: |
Leng F |
Year: |
2018 |
Journal: |
Nat Commun |
Title: |
Methylated DNMT1 and E2F1 are targeted for proteolysis by L3MBTL3 and CRL4DCAF5 ubiquitin ligase. |
Volume: |
9 |
Issue: |
1 |
Pages: |
1641 |
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Publication |
First Author: |
Qin G |
Year: |
2006 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Cell cycle regulator E2F1 modulates angiogenesis via p53-dependent transcriptional control of VEGF. |
Volume: |
103 |
Issue: |
29 |
Pages: |
11015-20 |
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Publication |
First Author: |
Endorf EB |
Year: |
2017 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Telomerase Reverse Transcriptase Deficiency Prevents Neointima Formation Through Chromatin Silencing of E2F1 Target Genes. |
Volume: |
37 |
Issue: |
2 |
Pages: |
301-311 |
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Publication |
First Author: |
Cloud JE |
Year: |
2002 |
Journal: |
Mol Cell Biol |
Title: |
Mutant mouse models reveal the relative roles of E2F1 and E2F3 in vivo. |
Volume: |
22 |
Issue: |
8 |
Pages: |
2663-72 |
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Publication |
First Author: |
DeRyckere D |
Year: |
2005 |
Journal: |
J Immunol |
Title: |
E2F1 and E2F2 are differentially required for homeostasis-driven and antigen-induced T cell proliferation in vivo. |
Volume: |
175 |
Issue: |
2 |
Pages: |
647-55 |
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Publication |
First Author: |
Hollern DP |
Year: |
2019 |
Journal: |
Sci Rep |
Title: |
E2F1 Drives Breast Cancer Metastasis by Regulating the Target Gene FGF13 and Altering Cell Migration. |
Volume: |
9 |
Issue: |
1 |
Pages: |
10718 |
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Publication |
First Author: |
Chen D |
Year: |
2008 |
Journal: |
J Biol Chem |
Title: |
E2F1 regulates the base excision repair gene XRCC1 and promotes DNA repair. |
Volume: |
283 |
Issue: |
22 |
Pages: |
15381-9 |
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Publication |
First Author: |
Gao X |
Year: |
2004 |
Journal: |
Virology |
Title: |
Role of cell cycle regulator E2F1 in regulating CD8 T cell responses during acute and chronic viral infection. |
Volume: |
324 |
Issue: |
2 |
Pages: |
567-76 |
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Publication |
First Author: |
Agger K |
Year: |
2005 |
Journal: |
Oncogene |
Title: |
Conditional E2F1 activation in transgenic mice causes testicular atrophy and dysplasia mimicking human CIS. |
Volume: |
24 |
Issue: |
5 |
Pages: |
780-9 |
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Publication |
First Author: |
Amasaki H |
Year: |
2003 |
Journal: |
Ann Anat |
Title: |
Distributional changes of BrdU, PCNA, E2F1 and PAL31 molecules in developing murine palatal rugae. |
Volume: |
185 |
Issue: |
6 |
Pages: |
517-23 |
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Publication |
First Author: |
Fajas L |
Year: |
2004 |
Journal: |
J Clin Invest |
Title: |
Impaired pancreatic growth, beta cell mass, and beta cell function in E2F1 (-/- )mice. |
Volume: |
113 |
Issue: |
9 |
Pages: |
1288-95 |
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Publication |
First Author: |
Kuwako K |
Year: |
2004 |
Journal: |
J Biol Chem |
Title: |
Necdin-related MAGE proteins differentially interact with the E2F1 transcription factor and the p75 neurotrophin receptor. |
Volume: |
279 |
Issue: |
3 |
Pages: |
1703-12 |
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Publication |
First Author: |
Hong W |
Year: |
2011 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Epigenetic involvement of Alien/ESET complex in thyroid hormone-mediated repression of E2F1 gene expression and cell proliferation. |
Volume: |
415 |
Issue: |
4 |
Pages: |
650-5 |
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Publication |
First Author: |
Jiang SX |
Year: |
2007 |
Journal: |
Mol Cell Biol |
Title: |
Neuropilin-1 is a direct target of the transcription factor E2F1 during cerebral ischemia-induced neuronal death in vivo. |
Volume: |
27 |
Issue: |
5 |
Pages: |
1696-705 |
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Publication |
First Author: |
Magri L |
Year: |
2014 |
Journal: |
J Neurosci |
Title: |
E2F1 coregulates cell cycle genes and chromatin components during the transition of oligodendrocyte progenitors from proliferation to differentiation. |
Volume: |
34 |
Issue: |
4 |
Pages: |
1481-93 |
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Publication |
First Author: |
Palmero I |
Year: |
2002 |
Journal: |
Oncogene |
Title: |
Activation of ARF by oncogenic stress in mouse fibroblasts is independent of E2F1 and E2F2. |
Volume: |
21 |
Issue: |
19 |
Pages: |
2939-47 |
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Publication |
First Author: |
Wang N |
Year: |
2016 |
Journal: |
PLoS One |
Title: |
E2F1 Hinders Skin Wound Healing by Repressing Vascular Endothelial Growth Factor (VEGF) Expression, Neovascularization, and Macrophage Recruitment. |
Volume: |
11 |
Issue: |
8 |
Pages: |
e0160411 |
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Publication |
First Author: |
Giovanni A |
Year: |
2000 |
Journal: |
J Biol Chem |
Title: |
E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3. |
Volume: |
275 |
Issue: |
16 |
Pages: |
11553-60 |
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Publication |
First Author: |
Jiang Z |
Year: |
2000 |
Journal: |
Dev Biol |
Title: |
E2F1 and p53 are dispensable, whereas p21(Waf1/Cip1) cooperates with Rb to restrict endoreduplication and apoptosis during skeletal myogenesis. |
Volume: |
227 |
Issue: |
1 |
Pages: |
8-41 |
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Publication |
First Author: |
Elena C |
Year: |
2010 |
Journal: |
Biochim Biophys Acta |
Title: |
Specific interaction between E2F1 and Sp1 regulates the expression of murine CTP:phosphocholine cytidylyltransferase alpha during the S phase. |
Volume: |
1801 |
Issue: |
4 |
Pages: |
537-46 |
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Publication |
First Author: |
Tsume M |
Year: |
2012 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Brd2 is required for cell cycle exit and neuronal differentiation through the E2F1 pathway in mouse neuroepithelial cells. |
Volume: |
425 |
Issue: |
4 |
Pages: |
762-8 |
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Publication |
First Author: |
Sangwan M |
Year: |
2012 |
Journal: |
Oncogene |
Title: |
Established and new mouse models reveal E2f1 and Cdk2 dependency of retinoblastoma, and expose effective strategies to block tumor initiation. |
Volume: |
31 |
Issue: |
48 |
Pages: |
5019-28 |
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Publication |
First Author: |
Yi Y |
Year: |
2015 |
Journal: |
J Urol |
Title: |
A Murine Model of K-RAS and β-Catenin Induced Renal Tumors Expresses High Levels of E2F1 and Resembles Human Wilms Tumor. |
Volume: |
194 |
Issue: |
6 |
Pages: |
1762-70 |
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Publication |
First Author: |
Liu Y |
Year: |
2000 |
Journal: |
Oncogene |
Title: |
E2F1 mediates ectopic proliferation and stage-specific p53-dependent apoptosis but not aberrant differentiation in the ocular lens of Rb deficient fetuses. |
Volume: |
19 |
Issue: |
52 |
Pages: |
6065-73 |
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