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Search results 1 to 100 out of 1191 for E2f1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Protein
Organism: Mus musculus/domesticus
Length: 430  
Fragment?: false
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
GXD Expression      
Probe: MGI:7461634
Assay Type: RT-PCR
Annotation Date: 2023-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7466102
Age: postnatal week 6
Specimen Label: E2F1
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:4839153
Assay Type: Immunohistochemistry
Annotation Date: 2010-11-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Pattern: Single cells
Stage: TS27
Assay Id: MGI:4839209
Age: postnatal day 0
Image: 2A - E2f1
Note: Expression is present in oligodendrocytes and oligoendrocyte progenitors.
Specimen Label: 2A - E2f1
Detected: true
Specimen Num: 3
Publication
First Author: Grouwels G
Year: 2010
Journal: Diabetes
Title: Ectopic expression of E2F1 stimulates beta-cell proliferation and function.
Volume: 59
Issue: 6
Pages: 1435-44
Publication
First Author: Russell JL
Year: 2002
Journal: Mol Cell Biol
Title: ARF differentially modulates apoptosis induced by E2F1 and Myc.
Volume: 22
Issue: 5
Pages: 1360-8
Publication
First Author: Lazzerini Denchi E
Year: 2005
Journal: EMBO Rep
Title: E2F1 is crucial for E2F-dependent apoptosis.
Volume: 6
Issue: 7
Pages: 661-8
Publication
First Author: Ladu S
Year: 2008
Journal: Gastroenterology
Title: E2F1 inhibits c-Myc-driven apoptosis via PIK3CA/Akt/mTOR and COX-2 in a mouse model of human liver cancer.
Volume: 135
Issue: 4
Pages: 1322-32
Publication
First Author: Li Y
Year: 1994
Journal: Mol Cell Biol
Title: Cloning, chromosomal location, and characterization of mouse E2F1.
Volume: 14
Issue: 3
Pages: 1861-9
Publication
First Author: Russell JL
Year: 2006
Journal: Oncogene
Title: E2F1 suppresses skin carcinogenesis via the ARF-p53 pathway.
Volume: 25
Issue: 6
Pages: 867-76
HT Experiment  
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Raimundo N
Year: 2012
Journal: Cell
Title: Mitochondrial stress engages E2F1 apoptotic signaling to cause deafness.
Volume: 148
Issue: 4
Pages: 716-26
Publication
First Author: Pierce AM
Year: 1999
Journal: Mol Cell Biol
Title: E2F1 has both oncogenic and tumor-suppressive properties in a transgenic model.
Volume: 19
Issue: 9
Pages: 6408-14
Publication
First Author: Wang D
Year: 2000
Journal: Mol Cell Biol
Title: E2F4 and E2F1 have similar proliferative properties but different apoptotic and oncogenic properties in vivo.
Volume: 20
Issue: 10
Pages: 3417-24
Publication
First Author: Holmberg C
Year: 1998
Journal: Oncogene
Title: E2F-1-induced p53-independent apoptosis in transgenic mice.
Volume: 17
Issue: 2
Pages: 143-55
Publication
First Author: Pierce AM
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Increased E2F1 activity induces skin tumors in mice heterozygous and nullizygous for p53.
Volume: 95
Issue: 15
Pages: 8858-63
Publication
First Author: Bourouh C
Year: 2022
Journal: Cell Rep
Title: The transcription factor E2F1 controls the GLP-1 receptor pathway in pancreatic β cells.
Volume: 40
Issue: 6
Pages: 111170
Publication  
First Author: Giralt A
Year: 2018
Journal: Mol Metab
Title: E2F1 promotes hepatic gluconeogenesis and contributes to hyperglycemia during diabetes.
Volume: 11
Pages: 104-112
Publication
First Author: Fedele M
Year: 2006
Journal: Cancer Cell
Title: HMGA2 induces pituitary tumorigenesis by enhancing E2F1 activity.
Volume: 9
Issue: 6
Pages: 459-71
Publication
First Author: Costa C
Year: 2013
Journal: Oncogene
Title: E2F1 loss induces spontaneous tumour development in Rb-deficient epidermis.
Volume: 32
Issue: 24
Pages: 2937-51
Publication
First Author: Hou ST
Year: 2000
Journal: J Neurochem
Title: The transcription factor E2F1 modulates apoptosis of neurons.
Volume: 75
Issue: 1
Pages: 91-100
Publication
First Author: Conner EA
Year: 2003
Journal: Biochem Biophys Res Commun
Title: E2F1 blocks and c-Myc accelerates hepatic ploidy in transgenic mouse models.
Volume: 302
Issue: 1
Pages: 114-20
Publication  
First Author: Wang B
Year: 2015
Journal: Nat Commun
Title: POH1 deubiquitylates and stabilizes E2F1 to promote tumour formation.
Volume: 6
Pages: 8704
Publication
First Author: Bartley SM
Year: 1998
Journal: Gene
Title: Characterization of the 3' untranslated region of mouse E2F1 mRNA.
Volume: 223
Issue: 1-2
Pages: 355-60
Publication
First Author: Wang L
Year: 2007
Journal: J Neurosci
Title: E2F1 works as a cell cycle suppressor in mature neurons.
Volume: 27
Issue: 46
Pages: 12555-64
Publication
First Author: Dassanayaka S
Year: 2019
Journal: Basic Res Cardiol
Title: E2f1 deletion attenuates infarct-induced ventricular remodeling without affecting O-GlcNAcylation.
Volume: 114
Issue: 4
Pages: 28
Publication
First Author: Denechaud PD
Year: 2016
Journal: J Clin Invest
Title: E2F1 mediates sustained lipogenesis and contributes to hepatic steatosis.
Volume: 126
Issue: 1
Pages: 137-50
Publication
First Author: Rounbehler RJ
Year: 2002
Journal: Cancer Res
Title: Inactivation of E2f1 enhances tumorigenesis in a Myc transgenic model.
Volume: 62
Issue: 11
Pages: 3276-81
Publication  
First Author: Lu Z
Year: 2014
Journal: Nat Commun
Title: Skp2 suppresses apoptosis in Rb1-deficient tumours by limiting E2F1 activity.
Volume: 5
Pages: 3463
Publication
First Author: Berton TR
Year: 2005
Journal: Oncogene
Title: Regulation of epidermal apoptosis and DNA repair by E2F1 in response to ultraviolet B radiation.
Volume: 24
Issue: 15
Pages: 2449-60
Publication
First Author: Wu M
Year: 2014
Journal: Cardiovasc Res
Title: E2F1 suppresses cardiac neovascularization by down-regulating VEGF and PlGF expression.
Volume: 104
Issue: 3
Pages: 412-22
Publication
First Author: Kent LN
Year: 2017
Journal: J Clin Invest
Title: Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma.
Volume: 127
Issue: 3
Pages: 830-842
Publication
First Author: Wolfram JA
Year: 2011
Journal: Int J Clin Exp Pathol
Title: The role of E2F1 in the development of hypertrophic cardiomyopathy.
Volume: 4
Issue: 5
Pages: 521-5
Publication
First Author: Chen D
Year: 2013
Journal: Cell Death Differ
Title: E2f2 induces cone photoreceptor apoptosis independent of E2f1 and E2f3.
Volume: 20
Issue: 7
Pages: 931-40
Publication
First Author: Baudino TA
Year: 2003
Journal: Mol Cell
Title: Myc-mediated proliferation and lymphomagenesis, but not apoptosis, are compromised by E2f1 loss.
Volume: 11
Issue: 4
Pages: 905-14
Publication
First Author: Carnevale J
Year: 2012
Journal: Mol Cell Biol
Title: DNA damage signals through differentially modified E2F1 molecules to induce apoptosis.
Volume: 32
Issue: 5
Pages: 900-12
Publication
First Author: Pellicano F
Year: 2018
Journal: Blood
Title: hsa-mir183/EGR1-mediated regulation of E2F1 is required for CML stem/progenitor cell survival.
Volume: 131
Issue: 14
Pages: 1532-1544
Publication
First Author: Rotgers E
Year: 2015
Journal: Andrology
Title: E2F1 controls germ cell apoptosis during the first wave of spermatogenesis.
Volume: 3
Issue: 5
Pages: 1000-14
Publication
First Author: Ting JH
Year: 2014
Journal: J Neurochem
Title: Targeted gene mutation of E2F1 evokes age-dependent synaptic disruption and behavioral deficits.
Volume: 129
Issue: 5
Pages: 850-63
GXD Expression    
Probe: MGI:6171655
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190165
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - E2f1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6171655
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190165
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - E2f1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6171655
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190165
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - E2f1
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6171655
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190165
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - E2f1
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6171655
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190165
Age: postnatal day 4
Specimen Label: Table S2 - P4 - E2f1
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6171655
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190165
Age: postnatal day 14
Specimen Label: Table S2 - P14 - E2f1
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6171655
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190165
Age: postnatal day 28
Specimen Label: Table S2 - P28 - E2f1
Detected: true
Specimen Num: 7
Publication
First Author: Miyajima M
Year: 1996
Journal: J Neurosci Res
Title: Overexpression of E2F1 in astrocytes leads to neoplastic transformation and changes in expression of retinoblastoma family members.
Volume: 46
Issue: 1
Pages: 108-13
Publication
First Author: Zacksenhaus E
Year: 1996
Journal: EMBO J
Title: Dual mechanisms of repression of E2F1 activity by the retinoblastoma gene product.
Volume: 15
Issue: 21
Pages: 5917-27
Publication
First Author: Lin SC
Year: 2001
Journal: Oncogene
Title: The proliferative and apoptotic activities of E2F1 in the mouse retina.
Volume: 20
Issue: 48
Pages: 7073-84
Publication  
First Author: Jorgez CJ
Year: 2021
Journal: Development
Title: E2F1 regulates testicular descent and controls spermatogenesis by influencing WNT4 signaling.
Volume: 148
Issue: 1
Publication  
First Author: Lai Q
Year: 2017
Journal: JCI Insight
Title: E2F1 inhibits circulating cholesterol clearance by regulating Pcsk9 expression in the liver.
Volume: 2
Issue: 10
Publication
First Author: González-Romero F
Year: 2021
Journal: Cancer Res
Title: E2F1 and E2F2-Mediated Repression of CPT2 Establishes a Lipid-Rich Tumor-Promoting Environment.
Volume: 81
Issue: 11
Pages: 2874-2887
Publication
First Author: Manickavinayaham S
Year: 2019
Journal: Nat Commun
Title: E2F1 acetylation directs p300/CBP-mediated histone acetylation at DNA double-strand breaks to facilitate repair.
Volume: 10
Issue: 1
Pages: 4951
Publication  
First Author: Tarangelo A
Year: 2015
Journal: Nat Commun
Title: Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression.
Volume: 6
Pages: 10028
Publication
First Author: Wikonkal NM
Year: 2003
Journal: Nat Cell Biol
Title: Inactivating E2f1 reverts apoptosis resistance and cancer sensitivity in Trp53-deficient mice.
Volume: 5
Issue: 7
Pages: 655-60
Publication
First Author: Biswas AK
Year: 2014
Journal: Cancer Res
Title: E2F1 responds to ultraviolet radiation by directly stimulating DNA repair and suppressing carcinogenesis.
Volume: 74
Issue: 12
Pages: 3369-77
Publication
First Author: García I
Year: 2000
Journal: Cell Growth Differ
Title: A role for E2F1 in the induction of apoptosis during thymic negative selection.
Volume: 11
Issue: 2
Pages: 91-8
Publication  
First Author: Xiong M
Year: 2021
Journal: Front Physiol
Title: Transcription Factor E2F1 Knockout Promotes Mice White Adipose Tissue Browning Through Autophagy Inhibition.
Volume: 12
Pages: 748040
Publication
First Author: Hsiao KM
Year: 1994
Journal: Genes Dev
Title: Multiple DNA elements are required for the growth regulation of the mouse E2F1 promoter.
Volume: 8
Issue: 13
Pages: 1526-37
Publication
First Author: Hyde RK
Year: 2002
Journal: Invest Ophthalmol Vis Sci
Title: Unique roles for E2F1 in the mouse lens in the absence of functional pRB proteins.
Volume: 43
Issue: 5
Pages: 1509-16
Publication
First Author: Warg LA
Year: 2012
Journal: Am J Physiol Lung Cell Mol Physiol
Title: The role of the E2F1 transcription factor in the innate immune response to systemic LPS.
Volume: 303
Issue: 5
Pages: L391-400
Publication
First Author: Salam MA
Year: 2004
Journal: J Immunol
Title: E2f1 mutation induces early onset of diabetes and Sjögren's syndrome in nonobese diabetic mice.
Volume: 173
Issue: 8
Pages: 4908-18
Publication
First Author: Iglesias-Ara A
Year: 2015
Journal: Cell Death Differ
Title: E2F1 and E2F2 prevent replicative stress and subsequent p53-dependent organ involution.
Volume: 22
Issue: 10
Pages: 1577-89
Publication
First Author: Zhu JW
Year: 2001
Journal: Mol Cell Biol
Title: E2F1 and E2F2 determine thresholds for antigen-induced T-cell proliferation and suppress tumorigenesis.
Volume: 21
Issue: 24
Pages: 8547-64
Publication
First Author: Pan H
Year: 1998
Journal: Mol Cell
Title: Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors.
Volume: 2
Issue: 3
Pages: 283-92
Publication
First Author: Zhu JW
Year: 1999
Journal: Cell Growth Differ
Title: A role for E2F1 in the induction of ARF, p53, and apoptosis during thymic negative selection.
Volume: 10
Issue: 12
Pages: 829-38
Publication
First Author: Leng F
Year: 2018
Journal: Nat Commun
Title: Methylated DNMT1 and E2F1 are targeted for proteolysis by L3MBTL3 and CRL4DCAF5 ubiquitin ligase.
Volume: 9
Issue: 1
Pages: 1641
Publication
First Author: Qin G
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Cell cycle regulator E2F1 modulates angiogenesis via p53-dependent transcriptional control of VEGF.
Volume: 103
Issue: 29
Pages: 11015-20
Publication
First Author: Endorf EB
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: Telomerase Reverse Transcriptase Deficiency Prevents Neointima Formation Through Chromatin Silencing of E2F1 Target Genes.
Volume: 37
Issue: 2
Pages: 301-311
Publication
First Author: Cloud JE
Year: 2002
Journal: Mol Cell Biol
Title: Mutant mouse models reveal the relative roles of E2F1 and E2F3 in vivo.
Volume: 22
Issue: 8
Pages: 2663-72
Publication
First Author: DeRyckere D
Year: 2005
Journal: J Immunol
Title: E2F1 and E2F2 are differentially required for homeostasis-driven and antigen-induced T cell proliferation in vivo.
Volume: 175
Issue: 2
Pages: 647-55
Publication
First Author: Hollern DP
Year: 2019
Journal: Sci Rep
Title: E2F1 Drives Breast Cancer Metastasis by Regulating the Target Gene FGF13 and Altering Cell Migration.
Volume: 9
Issue: 1
Pages: 10718
Publication
First Author: Chen D
Year: 2008
Journal: J Biol Chem
Title: E2F1 regulates the base excision repair gene XRCC1 and promotes DNA repair.
Volume: 283
Issue: 22
Pages: 15381-9
Publication
First Author: Gao X
Year: 2004
Journal: Virology
Title: Role of cell cycle regulator E2F1 in regulating CD8 T cell responses during acute and chronic viral infection.
Volume: 324
Issue: 2
Pages: 567-76
Publication
First Author: Agger K
Year: 2005
Journal: Oncogene
Title: Conditional E2F1 activation in transgenic mice causes testicular atrophy and dysplasia mimicking human CIS.
Volume: 24
Issue: 5
Pages: 780-9
Publication
First Author: Amasaki H
Year: 2003
Journal: Ann Anat
Title: Distributional changes of BrdU, PCNA, E2F1 and PAL31 molecules in developing murine palatal rugae.
Volume: 185
Issue: 6
Pages: 517-23
Publication
First Author: Fajas L
Year: 2004
Journal: J Clin Invest
Title: Impaired pancreatic growth, beta cell mass, and beta cell function in E2F1 (-/- )mice.
Volume: 113
Issue: 9
Pages: 1288-95
Publication
First Author: Kuwako K
Year: 2004
Journal: J Biol Chem
Title: Necdin-related MAGE proteins differentially interact with the E2F1 transcription factor and the p75 neurotrophin receptor.
Volume: 279
Issue: 3
Pages: 1703-12
Publication
First Author: Hong W
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Epigenetic involvement of Alien/ESET complex in thyroid hormone-mediated repression of E2F1 gene expression and cell proliferation.
Volume: 415
Issue: 4
Pages: 650-5
Publication
First Author: Jiang SX
Year: 2007
Journal: Mol Cell Biol
Title: Neuropilin-1 is a direct target of the transcription factor E2F1 during cerebral ischemia-induced neuronal death in vivo.
Volume: 27
Issue: 5
Pages: 1696-705
Publication
First Author: Magri L
Year: 2014
Journal: J Neurosci
Title: E2F1 coregulates cell cycle genes and chromatin components during the transition of oligodendrocyte progenitors from proliferation to differentiation.
Volume: 34
Issue: 4
Pages: 1481-93
Publication
First Author: Palmero I
Year: 2002
Journal: Oncogene
Title: Activation of ARF by oncogenic stress in mouse fibroblasts is independent of E2F1 and E2F2.
Volume: 21
Issue: 19
Pages: 2939-47
Publication
First Author: Wang N
Year: 2016
Journal: PLoS One
Title: E2F1 Hinders Skin Wound Healing by Repressing Vascular Endothelial Growth Factor (VEGF) Expression, Neovascularization, and Macrophage Recruitment.
Volume: 11
Issue: 8
Pages: e0160411
Publication
First Author: Giovanni A
Year: 2000
Journal: J Biol Chem
Title: E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3.
Volume: 275
Issue: 16
Pages: 11553-60
Publication
First Author: Jiang Z
Year: 2000
Journal: Dev Biol
Title: E2F1 and p53 are dispensable, whereas p21(Waf1/Cip1) cooperates with Rb to restrict endoreduplication and apoptosis during skeletal myogenesis.
Volume: 227
Issue: 1
Pages: 8-41
Publication
First Author: Elena C
Year: 2010
Journal: Biochim Biophys Acta
Title: Specific interaction between E2F1 and Sp1 regulates the expression of murine CTP:phosphocholine cytidylyltransferase alpha during the S phase.
Volume: 1801
Issue: 4
Pages: 537-46
Publication
First Author: Tsume M
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Brd2 is required for cell cycle exit and neuronal differentiation through the E2F1 pathway in mouse neuroepithelial cells.
Volume: 425
Issue: 4
Pages: 762-8
Publication
First Author: Sangwan M
Year: 2012
Journal: Oncogene
Title: Established and new mouse models reveal E2f1 and Cdk2 dependency of retinoblastoma, and expose effective strategies to block tumor initiation.
Volume: 31
Issue: 48
Pages: 5019-28
Publication
First Author: Yi Y
Year: 2015
Journal: J Urol
Title: A Murine Model of K-RAS and β-Catenin Induced Renal Tumors Expresses High Levels of E2F1 and Resembles Human Wilms Tumor.
Volume: 194
Issue: 6
Pages: 1762-70
Publication
First Author: Liu Y
Year: 2000
Journal: Oncogene
Title: E2F1 mediates ectopic proliferation and stage-specific p53-dependent apoptosis but not aberrant differentiation in the ocular lens of Rb deficient fetuses.
Volume: 19
Issue: 52
Pages: 6065-73