Type |
Details |
Score |
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1113
|
Fragment?: |
false |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Regulatory Region |
Type: |
enhancer |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Ahituv N |
Year: |
2007 |
Journal: |
PLoS Biol |
Title: |
Deletion of ultraconserved elements yields viable mice. |
Volume: |
5 |
Issue: |
9 |
Pages: |
e234 |
|
•
•
•
•
•
|
Publication |
First Author: |
Andrew Nesbit M |
Year: |
2004 |
Journal: |
Genomics |
Title: |
X-linked hypoparathyroidism region on Xq27 is evolutionarily conserved with regions on 3q26 and 13q34 and contains a novel P-type ATPase. |
Volume: |
84 |
Issue: |
6 |
Pages: |
1060-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu Q |
Year: |
2012 |
Journal: |
FEBS Lett |
Title: |
P4-ATPase ATP8A2 acts in synergy with CDC50A to enhance neurite outgrowth. |
Volume: |
586 |
Issue: |
13 |
Pages: |
1803-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Folmer DE |
Year: |
2012 |
Journal: |
J Histochem Cytochem |
Title: |
Cellular localization and biochemical analysis of mammalian CDC50A, a glycosylated β-subunit for P4 ATPases. |
Volume: |
60 |
Issue: |
3 |
Pages: |
205-18 |
|
•
•
•
•
•
|
Publication |
First Author: |
Muñoz-MartÃnez F |
Year: |
2010 |
Journal: |
Biochem Pharmacol |
Title: |
CDC50A plays a key role in the uptake of the anticancer drug perifosine in human carcinoma cells. |
Volume: |
80 |
Issue: |
6 |
Pages: |
793-800 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Cell cycle control protein 50A (CDC50A, also known as TMEM30A) is an accessory component of the phospholipid-transporting ATPase (P4-ATPase) complex which catalyses the hydrolysis of ATP coupled to the transport of phospholipids across the membrane []. It can interact with several P4-ATPases, such as ATP8A1, ATP8A2, ATP8B1, ATP8B2, ATP11A, ATP11B and ATP11C [, , ]. CDC50A is a terminal-glycosylated glycoprotein and is expressed in hepatocytes and liver sinusoidal endothelial cells. In pancreas and stomach, it localises to secretory vesicles, while in kidney, it localises to the apical region of proximal convoluted tubules of the cortex []. In human carcinoma cells, CDC50A plays a key role in the uptake of the anticancer drug perifosine []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Ochiai Y |
Year: |
2022 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Inefficient development of syncytiotrophoblasts in the Atp11a-deficient mouse placenta. |
Volume: |
119 |
Issue: |
18 |
Pages: |
e2200582119 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu L |
Year: |
2017 |
Journal: |
Am J Pathol |
Title: |
Hepatic Tmem30a Deficiency Causes Intrahepatic Cholestasis by Impairing Expression and Localization of Bile Salt Transporters. |
Volume: |
187 |
Issue: |
12 |
Pages: |
2775-2787 |
|
•
•
•
•
•
|
Publication |
First Author: |
Segawa K |
Year: |
2018 |
Journal: |
J Biol Chem |
Title: |
The CDC50A extracellular domain is required for forming a functional complex with and chaperoning phospholipid flippases to the plasma membrane. |
Volume: |
293 |
Issue: |
6 |
Pages: |
2172-2182 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liou AY |
Year: |
2019 |
Journal: |
J Biol Chem |
Title: |
Identification and functional analyses of disease-associated P4-ATPase phospholipid flippase variants in red blood cells. |
Volume: |
294 |
Issue: |
17 |
Pages: |
6809-6821 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kato U |
Year: |
2013 |
Journal: |
J Biol Chem |
Title: |
Role for phospholipid flippase complex of ATP8A1 and CDC50A proteins in cell migration. |
Volume: |
288 |
Issue: |
7 |
Pages: |
4922-34 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
364
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
328
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
van der Velden LM |
Year: |
2010 |
Journal: |
J Biol Chem |
Title: |
Heteromeric interactions required for abundance and subcellular localization of human CDC50 proteins and class 1 P4-ATPases. |
Volume: |
285 |
Issue: |
51 |
Pages: |
40088-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|