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Search results 101 to 200 out of 569 for Mc4r

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Type Details Score
Publication
30545847 | J:272371
 
First Author: Matharu N
Year: 2019
Journal: Science
Title: CRISPR-mediated activation of a promoter or enhancer rescues obesity caused by haploinsufficiency.
Volume: 363
Issue: 6424
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Publication
16005545 | J:263242
First Author: Shaw AM
Year: 2005
Journal: Peptides
Title: Ghrelin-induced food intake and growth hormone secretion are altered in melanocortin 3 and 4 receptor knockout mice.
Volume: 26
Issue: 10
Pages: 1720-7
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Publication
30756300 | J:295504
First Author: Semple E
Year: 2019
Journal: Mol Neurobiol
Title: Oxytocin Neurons Enable Melanocortin Regulation of Male Sexual Function in Mice.
Volume: 56
Issue: 9
Pages: 6310-6323
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Publication
32976803 | J:314522
First Author: Reinoß P
Year: 2020
Journal: Curr Biol
Title: Hypothalamic Pomc Neurons Innervate the Spinal Cord and Modulate the Excitability of Premotor Circuits.
Volume: 30
Issue: 23
Pages: 4579-4593.e7
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Publication
21969101 | J:225022
First Author: Bolze F
Year: 2013
Journal: Pharmacogenomics J
Title: Characterization of the melanocortin-4-receptor nonsense mutation W16X in vitro and in vivo.
Volume: 13
Issue: 1
Pages: 80-93
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Publication
17143585 | J:116205
First Author: Meehan TP
Year: 2006
Journal: Mamm Genome
Title: Point mutations in the melanocortin-4 receptor cause variable obesity in mice.
Volume: 17
Issue: 12
Pages: 1162-71
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Publication
9916804 | J:110941
First Author: Marsh DJ
Year: 1999
Journal: Nat Genet
Title: Response of melanocortin-4 receptor-deficient mice to anorectic and orexigenic peptides.
Volume: 21
Issue: 1
Pages: 119-22
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Publication
18971258 | J:146017
First Author: Haskell-Luevano C
Year: 2009
Journal: FASEB J
Title: Voluntary exercise prevents the obese and diabetic metabolic syndrome of the melanocortin-4 receptor knockout mouse.
Volume: 23
Issue: 2
Pages: 642-55
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Publication
16027245 | J:114301
First Author: Tallam LS
Year: 2005
Journal: Hypertension
Title: Melanocortin-4 receptor-deficient mice are not hypertensive or salt-sensitive despite obesity, hyperinsulinemia, and hyperleptinemia.
Volume: 46
Issue: 2
Pages: 326-32
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Publication
16754792 | J:135735
First Author: Tallam LS
Year: 2006
Journal: Hypertension
Title: Melanocortin-4 receptor mediates chronic cardiovascular and metabolic actions of leptin.
Volume: 48
Issue: 1
Pages: 58-64
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Publication
14559977 | J:125996
First Author: Arens J
Year: 2003
Journal: Physiol Genomics
Title: Age-dependent hypothalamic expression of neuropeptides in wild-type and melanocortin-4 receptor-deficient mice.
Volume: 16
Issue: 1
Pages: 38-46
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Publication
11027312 | J:65426
First Author: Ste Marie L
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: A metabolic defect promotes obesity in mice lacking melanocortin-4 receptors.
Volume: 97
Issue: 22
Pages: 12339-44
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Publication
12644632 | J:84047
First Author: Weide K
Year: 2003
Journal: Physiol Genomics
Title: Hyperphagia, not hypometabolism, causes early onset obesity in melanocortin-4 receptor knockout mice.
Volume: 13
Issue: 1
Pages: 47-56
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Publication
23569235 | J:196159
First Author: Panaro BL
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Melanocortin-4 receptor mutations paradoxically reduce preference for palatable foods.
Volume: 110
Issue: 17
Pages: 7050-5
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Publication
22848742 | J:189687
First Author: Braun TP
Year: 2012
Journal: PLoS One
Title: Regulation of lean mass, bone mass, and exercise tolerance by the central melanocortin system.
Volume: 7
Issue: 7
Pages: e42183
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Publication
19309531 | J:157144
 
First Author: Sandrock M
Year: 2009
Journal: Reprod Biol Endocrinol
Title: Reduction in corpora lutea number in obese melanocortin-4-receptor-deficient mice.
Volume: 7
Pages: 24
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Publication
24586817 | J:213822
First Author: Ye DW
Year: 2014
Journal: PLoS One
Title: Motor cortex-periaqueductal gray-spinal cord neuronal circuitry may involve in modulation of nociception: a virally mediated transsynaptic tracing study in spinally transected transgenic mouse model.
Volume: 9
Issue: 2
Pages: e89486
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Publication
28093215 | J:243145
 
First Author: Agosti F
Year: 2017
Journal: Neuroscience
Title: Melanocortin 4 receptor constitutive activity inhibits L-type voltage-gated calcium channels in neurons.
Volume: 346
Pages: 102-112
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Publication
28878020 | J:246504
First Author: Cooney KA
Year: 2017
Journal: J Biol Chem
Title: Lipid stress inhibits endocytosis of melanocortin-4 receptor from modified clathrin-enriched sites and impairs receptor desensitization.
Volume: 292
Issue: 43
Pages: 17731-17745
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Publication
33795520 | J:304754
 
First Author: Sweeney P
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Network dynamics of hypothalamic feeding neurons.
Volume: 118
Issue: 14
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Publication
33434184 | J:305726
 
First Author: René P
Year: 2021
Journal: JCI Insight
Title: Pharmacological chaperone action in humanized mouse models of MC4R-linked obesity.
Volume: 6
Issue: 4
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Publication
22592759 | J:315247
First Author: Gautron L
Year: 2012
Journal: J Comp Neurol
Title: Melanocortin-4 receptor expression in different classes of spinal and vagal primary afferent neurons in the mouse.
Volume: 520
Issue: 17
Pages: 3933-48
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Publication
37957201 | J:342628
First Author: Mori K
Year: 2023
Journal: Sci Rep
Title: Melanocortin-4 receptor in macrophages attenuated angiotensin II-induced abdominal aortic aneurysm in mice.
Volume: 13
Issue: 1
Pages: 19768
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Publication
29911992 | J:265438
First Author: Klawonn AM
Year: 2018
Journal: J Clin Invest
Title: Motivational valence is determined by striatal melanocortin 4 receptors.
Volume: 128
Issue: 7
Pages: 3160-3170
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Publication
25453189 | J:218759
First Author: Panaro BL
Year: 2014
Journal: Cell Metab
Title: The melanocortin-4 receptor is expressed in enteroendocrine L cells and regulates the release of peptide YY and glucagon-like peptide 1 in vivo.
Volume: 20
Issue: 6
Pages: 1018-29
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Publication
19036977 | J:142503
First Author: Kawahara Y
Year: 2008
Journal: J Neurosci
Title: Dysregulated editing of serotonin 2C receptor mRNAs results in energy dissipation and loss of fat mass.
Volume: 28
Issue: 48
Pages: 12834-44
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Publication
28003536 | J:238775
First Author: Chen X
Year: 2017
Journal: Reproduction
Title: Deficient melanocortin-4 receptor causes abnormal reproductive neuroendocrine profile in female mice.
Volume: 153
Issue: 3
Pages: 267-276
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Publication
19605765 | J:152189
First Author: do Carmo JM
Year: 2009
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Impact of obesity on renal structure and function in the presence and absence of hypertension: evidence from melanocortin-4 receptor-deficient mice.
Volume: 297
Issue: 3
Pages: R803-12
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Publication
36323255 | J:333430
First Author: Ju SH
Year: 2022
Journal: Cell Rep
Title: Melanocortin-4 receptors activate sympathetic preganglionic neurons and elevate blood pressure via TRPV1.
Volume: 41
Issue: 5
Pages: 111579
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Publication
37681411 | J:342501
 
First Author: Matsukawa T
Year: 2023
Journal: JCI Insight
Title: Hepatic FASN deficiency differentially affects nonalcoholic fatty liver disease and diabetes in mouse obesity models.
Volume: 8
Issue: 17
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Publication
24828650 | J:211263
First Author: Thiebaud N
Year: 2014
Journal: J Neurosci
Title: Hyperlipidemic diet causes loss of olfactory sensory neurons, reduces olfactory discrimination, and disrupts odor-reversal learning.
Volume: 34
Issue: 20
Pages: 6970-84
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Publication
16614075 | J:117473
First Author: Ahn JD
Year: 2006
Journal: Endocrinology
Title: Cart overexpression is the only identifiable cause of high bone mass in melanocortin 4 receptor deficiency.
Volume: 147
Issue: 7
Pages: 3196-202
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Publication
32229422 | J:308997
 
First Author: Xiao C
Year: 2020
Journal: Mol Metab
Title: BRS3 in both MC4R- and SIM1-expressing neurons regulates energy homeostasis in mice.
Volume: 36
Pages: 100969
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Publication
16469808 | J:128237
First Author: Sutton GM
Year: 2006
Journal: Endocrinology
Title: Diet-genotype interactions in the development of the obese, insulin-resistant phenotype of C57BL/6J mice lacking melanocortin-3 or -4 receptors.
Volume: 147
Issue: 5
Pages: 2183-96
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Publication
12796784 | J:84073
First Author: Xu B
Year: 2003
Journal: Nat Neurosci
Title: Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor.
Volume: 6
Issue: 7
Pages: 736-42
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Publication
27869800 | J:303221
First Author: Fenselau H
Year: 2017
Journal: Nat Neurosci
Title: A rapidly acting glutamatergic ARC→PVH satiety circuit postsynaptically regulated by α-MSH.
Volume: 20
Issue: 1
Pages: 42-51
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Publication
20096642 | J:158348
First Author: Guan XM
Year: 2010
Journal: Cell Metab
Title: Regulation of energy homeostasis by bombesin receptor subtype-3: selective receptor agonists for the treatment of obesity.
Volume: 11
Issue: 2
Pages: 101-12
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Publication
25980347 | J:226133
First Author: Ottaway N
Year: 2015
Journal: Cell Metab
Title: Diet-induced obese mice retain endogenous leptin action.
Volume: 21
Issue: 6
Pages: 877-82
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Publication
29794140 | J:267133
First Author: Podyma B
Year: 2018
Journal: J Biol Chem
Title: The stimulatory G protein Gsα is required in melanocortin 4 receptor-expressing cells for normal energy balance, thermogenesis, and glucose metabolism.
Volume: 293
Issue: 28
Pages: 10993-11005
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Publication
17932216 | J:141477
First Author: Trevaskis JL
Year: 2008
Journal: Endocrinology
Title: Counterintuitive effects of double-heterozygous null melanocortin-4 receptor and leptin genes on diet-induced obesity and insulin resistance in C57BL/6J mice.
Volume: 149
Issue: 1
Pages: 174-84
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Publication
14551222 | J:96671
First Author: Albarado DC
Year: 2004
Journal: Endocrinology
Title: Impaired coordination of nutrient intake and substrate oxidation in melanocortin-4 receptor knockout mice.
Volume: 145
Issue: 1
Pages: 243-52
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Publication
15994342 | J:101555
First Author: Trevaskis JL
Year: 2005
Journal: Endocrinology
Title: Double leptin and melanocortin-4 receptor gene mutations have an additive effect on fat mass and are associated with reduced effects of leptin on weight loss and food intake.
Volume: 146
Issue: 10
Pages: 4257-65
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Publication
19648111 | J:156355
First Author: Büch TR
Year: 2009
Journal: J Biol Chem
Title: Pertussis toxin-sensitive signaling of melanocortin-4 receptors in hypothalamic GT1-7 cells defines agouti-related protein as a biased agonist.
Volume: 284
Issue: 39
Pages: 26411-20
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Publication
21664420 | J:183737
First Author: Wankhade UD
Year: 2011
Journal: Mol Cell Endocrinol
Title: Melanocortin 4 receptor is a transcriptional target of nescient helix-loop-helix-2.
Volume: 341
Issue: 1-2
Pages: 39-47
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Publication
30209265 | J:318534
First Author: Yoon YR
Year: 2018
Journal: Exp Mol Med
Title: Glucose-regulated protein 78 binds to and regulates the melanocortin-4 receptor.
Volume: 50
Issue: 9
Pages: 1-14
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Publication
23754400 | J:197974
First Author: Xu P
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Double deletion of melanocortin 4 receptors and SAPAP3 corrects compulsive behavior and obesity in mice.
Volume: 110
Issue: 26
Pages: 10759-64
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Publication
25915476 | J:222852
First Author: Garfield AS
Year: 2015
Journal: Nat Neurosci
Title: A neural basis for melanocortin-4 receptor-regulated appetite.
Volume: 18
Issue: 6
Pages: 863-71
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Publication
18172198 | J:131039
First Author: Czyzyk TA
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Disruption of the RIIbeta subunit of PKA reverses the obesity syndrome of Agouti lethal yellow mice.
Volume: 105
Issue: 1
Pages: 276-81
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Publication
20160073 | J:158580
First Author: Decherf S
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Thyroid hormone exerts negative feedback on hypothalamic type 4 melanocortin receptor expression.
Volume: 107
Issue: 9
Pages: 4471-6
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Publication
21048120 | J:166702
First Author: Xu Y
Year: 2010
Journal: J Neurosci
Title: A serotonin and melanocortin circuit mediates D-fenfluramine anorexia.
Volume: 30
Issue: 44
Pages: 14630-4
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Publication
27408780 | J:247552
First Author: Mavrikaki M
Year: 2016
Journal: Mol Metab
Title: Melanocortin-3 receptors in the limbic system mediate feeding-related motivational responses during weight loss.
Volume: 5
Issue: 7
Pages: 566-79
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Publication
32895383 | J:297247
First Author: Bentsen MA
Year: 2020
Journal: Nat Commun
Title: Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission.
Volume: 11
Issue: 1
Pages: 4458
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Publication
26974347 | J:269717
   
First Author: D'Agostino G
Year: 2016
Journal: Elife
Title: Appetite controlled by a cholecystokinin nucleus of the solitary tract to hypothalamus neurocircuit.
Volume: 5
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Publication
19036988 | J:142498
First Author: Sutton GM
Year: 2008
Journal: J Neurosci
Title: The melanocortin-3 receptor is required for entrainment to meal intake.
Volume: 28
Issue: 48
Pages: 12946-55
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Publication
27991864 | J:239834
First Author: Chen M
Year: 2017
Journal: J Clin Invest
Title: Gsα deficiency in the dorsomedial hypothalamus underlies obesity associated with Gsα mutations.
Volume: 127
Issue: 2
Pages: 500-510
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Publication
16638826 | J:112364
First Author: Phan LK
Year: 2006
Journal: Am J Physiol Endocrinol Metab
Title: The mahoganoid mutation (Mgrn1md) improves insulin sensitivity in mice with mutations in the melanocortin signaling pathway independently of effects on adiposity.
Volume: 291
Issue: 3
Pages: E611-20
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Publication
22761160 | J:189527
First Author: De Jonghe BC
Year: 2012
Journal: Am J Physiol Endocrinol Metab
Title: Food intake reductions and increases in energetic responses by hindbrain leptin and melanotan II are enhanced in mice with POMC-specific PTP1B deficiency.
Volume: 303
Issue: 5
Pages: E644-51
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Publication
30353008 | J:267780
First Author: Clemmensen C
Year: 2018
Journal: Nat Commun
Title: Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes.
Volume: 9
Issue: 1
Pages: 4304
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Publication
24093681 | J:206003
First Author: Krashes MJ
Year: 2013
Journal: Cell Metab
Title: Rapid versus delayed stimulation of feeding by the endogenously released AgRP neuron mediators GABA, NPY, and AgRP.
Volume: 18
Issue: 4
Pages: 588-95
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Publication
30938715 | J:290747
First Author: Bouyakdan K
Year: 2019
Journal: J Clin Invest
Title: The gliotransmitter ACBP controls feeding and energy homeostasis via the melanocortin system.
Volume: 129
Issue: 6
Pages: 2417-2430
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Publication
20164094 | J:162835
First Author: Iqbal J
Year: 2010
Journal: J Lipid Res
Title: An intrinsic gut leptin-melanocortin pathway modulates intestinal microsomal triglyceride transfer protein and lipid absorption.
Volume: 51
Issue: 7
Pages: 1929-42
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Publication
24981835 | J:215467
First Author: Lute B
Year: 2014
Journal: Cell Metab
Title: Biphasic effect of melanocortin agonists on metabolic rate and body temperature.
Volume: 20
Issue: 2
Pages: 333-45
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Publication
27558671 | J:318399
First Author: Tan HY
Year: 2016
Journal: J Physiol
Title: Hyperphagia in male melanocortin 4 receptor deficient mice promotes growth independently of growth hormone.
Volume: 594
Issue: 24
Pages: 7309-7326
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Publication
27708159 | J:236520
First Author: Zhang Z
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Insulin resistance and diabetes caused by genetic or diet-induced KBTBD2 deficiency in mice.
Volume: 113
Issue: 42
Pages: E6418-E6426
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Publication
19570576 | J:156563
First Author: García-Tornadú I
Year: 2009
Journal: Neuropeptides
Title: Hypothalamic orexin, OX1, alphaMSH, NPY and MCRs expression in dopaminergic D2R knockout mice.
Volume: 43
Issue: 4
Pages: 267-74
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Publication
24813890 | J:211797
First Author: Gonçalves GH
Year: 2014
Journal: Cell Rep
Title: Hypothalamic agouti-related peptide neurons and the central melanocortin system are crucial mediators of leptin's antidiabetic actions.
Volume: 7
Issue: 4
Pages: 1093-103
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Publication
29031711 | J:336038
First Author: Burke LK
Year: 2017
Journal: Mol Metab
Title: Lorcaserin improves glycemic control via a melanocortin neurocircuit.
Volume: 6
Issue: 10
Pages: 1092-1102
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Publication
23312282 | J:195073
First Author: Arteaga-Solis E
Year: 2013
Journal: Cell Metab
Title: Inhibition of leptin regulation of parasympathetic signaling as a cause of extreme body weight-associated asthma.
Volume: 17
Issue: 1
Pages: 35-48
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Protein Coding Gene
MGP_CAROLIEiJ_G0022362 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0024518 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0024485 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0024455 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0024484 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0024252 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_99457 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0024931 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0023725 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0024222 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0024352 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0024318 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0024436 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0024347 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0024978 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0023468 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0023789 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0019091 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0023273 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
7854347 | J:21793
First Author: Mountjoy KG
Year: 1994
Journal: Mol Endocrinol
Title: Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain.
Volume: 8
Issue: 10
Pages: 1298-308
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Publication
22785313 | J:186695
First Author: Lim BK
Year: 2012
Journal: Nature
Title: Anhedonia requires MC4R-mediated synaptic adaptations in nucleus accumbens.
Volume: 487
Issue: 7406
Pages: 183-9
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Publication
- | J:225939
     
First Author: Solt R
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for halloween
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Publication
9019399 | J:38224
First Author: Huszar D
Year: 1997
Journal: Cell
Title: Targeted disruption of the melanocortin-4 receptor results in obesity in mice.
Volume: 88
Issue: 1
Pages: 131-41
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Publication
19721009 | J:154190
First Author: Yang H
Year: 2009
Journal: Blood
Title: Obesity accelerates thymic aging.
Volume: 114
Issue: 18
Pages: 3803-12
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Publication
10951699 | J:63775
First Author: Chen AS
Year: 2000
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